IMP
Process View
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| HLA-C | major histocompatibility complex, class I, C | 0.998 | ||
| HLA-B | major histocompatibility complex, class I, B | 0.997 | ||
| HLA-A | major histocompatibility complex, class I, A | 0.995 | ||
| B2M | beta-2-microglobulin | 0.992 | ||
| HLA-G | major histocompatibility complex, class I, G | 0.968 | Human | |
| HLA-E | major histocompatibility complex, class I, E | 0.958 | Human | |
| HLA-F | major histocompatibility complex, class I, F | 0.901 | Human | |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.887 | ||
| TAPBP | TAP binding protein (tapasin) | 0.721 | ||
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 0.050 | ||
| IFITM2 | interferon induced transmembrane protein 2 (1-8D) | 0.012 | ||
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.012 | Mouse |