Homo sapiens

182 known processes

PPARA

peroxisome proliferator-activated receptor alpha

(Aliases: PPARalpha,NR1C1,PPAR,MGC2452,hPPAR,MGC2237)

PPARA biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter GO:0072367 4 0.999
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 3 0.999
regulation of glycolytic process by regulation of transcription from rna polymerase ii promoter GO:0072361 2 0.998
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.983
negative regulation of transcription initiation from rna polymerase ii promoter GO:0060633 3 0.965
cranial nerve development GO:0021545 4 0.959
memory GO:0007613 3 0.947
lung epithelial cell differentiation GO:0060487 1 0.934
monocarboxylic acid metabolic process GO:0032787 185 0.891
organ morphogenesis GO:0009887 147 0.864
Mouse
cell proliferation in forebrain GO:0021846 1 0.863
chromatin modification GO:0016568 298 0.843
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.840
leukocyte differentiation GO:0002521 98 0.838
Human
positive regulation of interleukin 5 production GO:0032754 3 0.801
positive regulation of developmental process GO:0051094 314 0.792
Human
response to oxygen containing compound GO:1901700 369 0.791
Human Rat
lipid metabolic process GO:0006629 381 0.761
Human Mouse Rat
positive regulation of organ growth GO:0046622 2 0.761
cellular ketone metabolic process GO:0042180 80 0.744
nerve development GO:0021675 4 0.738
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.730
cell activation GO:0001775 213 0.706
negative regulation of multicellular organismal process GO:0051241 317 0.686
lipid transport GO:0006869 90 0.668
t cell activation GO:0042110 99 0.663
leukocyte activation GO:0045321 164 0.650
purine nucleoside monophosphate catabolic process GO:0009128 158 0.649
intracellular bile acid receptor signaling pathway GO:0038185 1 0.648
Human
segmentation GO:0035282 4 0.640
cell development GO:0048468 328 0.639
Human
response to organonitrogen compound GO:0010243 156 0.638
Human Rat
hemopoiesis GO:0030097 180 0.632
Human
skeletal system development GO:0001501 79 0.630
cellular response to hormone stimulus GO:0032870 125 0.616
thalamus development GO:0021794 2 0.600
neurogenesis GO:0022008 169 0.599
pyruvate metabolic process GO:0006090 26 0.582
protein deacetylation GO:0006476 38 0.579
nervous system development GO:0007399 293 0.578
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.571
nucleoside phosphate catabolic process GO:1901292 412 0.570
histone deacetylation GO:0016575 32 0.557
glycolytic process GO:0006096 17 0.557
chemical homeostasis GO:0048878 306 0.554
Human
purine ribonucleotide catabolic process GO:0009154 404 0.539
hematopoietic or lymphoid organ development GO:0048534 186 0.537
Human
vitamin d receptor signaling pathway GO:0070561 4 0.536
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.533
carbohydrate metabolic process GO:0005975 207 0.530
response to cytokine GO:0034097 232 0.528
Human
behavior GO:0007610 112 0.525
Rat
regulation of lipid metabolic process GO:0019216 96 0.521
Human Mouse
nucleoside catabolic process GO:0009164 408 0.517
neuron differentiation GO:0030182 138 0.510
response to other organism GO:0051707 261 0.508
regulation of cellular ketone metabolic process GO:0010565 50 0.498
immune system development GO:0002520 195 0.495
Human
t helper 2 cell differentiation GO:0045064 1 0.494
cellular response to organic cyclic compound GO:0071407 127 0.492
response to hormone GO:0009725 175 0.492
system process GO:0003008 349 0.490
Human Rat
cellular response to oxidative stress GO:0034599 85 0.484
single organism carbohydrate metabolic process GO:0044723 193 0.478
epithelium development GO:0060429 227 0.471
Human Mouse
glycosyl compound catabolic process GO:1901658 413 0.465
covalent chromatin modification GO:0016569 254 0.460
regulation of carbohydrate metabolic process GO:0006109 54 0.450
regulation of peptide hormone secretion GO:0090276 41 0.439
cellular response to endogenous stimulus GO:0071495 336 0.438
atp dependent chromatin remodeling GO:0043044 25 0.438
peroxisome organization GO:0007031 28 0.433
ribonucleoside triphosphate metabolic process GO:0009199 412 0.433
atp catabolic process GO:0006200 157 0.418
cholesterol homeostasis GO:0042632 28 0.408
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.407
Human
t cell differentiation GO:0030217 29 0.407
blastoderm segmentation GO:0007350 2 0.406
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.401
cellular carbohydrate metabolic process GO:0044262 84 0.396
central nervous system development GO:0007417 123 0.392
inner ear morphogenesis GO:0042472 4 0.381
mating GO:0007618 1 0.380
peptide secretion GO:0002790 51 0.375
immune response GO:0006955 307 0.372
Human
lung cell differentiation GO:0060479 1 0.369
transcription from rna polymerase iii promoter GO:0006383 19 0.356
purine ribonucleoside catabolic process GO:0046130 398 0.355
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 5 0.352
single organism carbohydrate catabolic process GO:0044724 33 0.352
cardiovascular system development GO:0072358 262 0.351
Rat
nucleoside monophosphate catabolic process GO:0009125 159 0.350
negative regulation of cell proliferation GO:0008285 228 0.350
Human
purine nucleoside triphosphate catabolic process GO:0009146 392 0.346
response to lipid GO:0033993 206 0.336
lymphocyte differentiation GO:0030098 35 0.333
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.326
regulation of hormone levels GO:0010817 125 0.324
ribonucleoside triphosphate catabolic process GO:0009203 391 0.320
sensory organ development GO:0007423 52 0.312
lung epithelium development GO:0060428 7 0.307
cell morphogenesis GO:0000902 296 0.304
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.299
positive regulation of t helper cell differentiation GO:0045624 2 0.296
cellular response to steroid hormone stimulus GO:0071383 37 0.296
heart morphogenesis GO:0003007 48 0.296
nucleoside triphosphate catabolic process GO:0009143 394 0.293
purine ribonucleoside metabolic process GO:0046128 437 0.288
negative regulation of locomotion GO:0040013 118 0.287
ribonucleotide catabolic process GO:0009261 405 0.287
regulation of mapk cascade GO:0043408 262 0.276
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.273
Human
canonical wnt signaling pathway GO:0060070 116 0.272
cellular response to organonitrogen compound GO:0071417 124 0.264
Human
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.264
response to alcohol GO:0097305 64 0.263
Human
cellular response to oxygen containing compound GO:1901701 276 0.259
Human
regulation of cell differentiation GO:0045595 393 0.258
regulation of hormone secretion GO:0046883 57 0.247
myeloid cell differentiation GO:0030099 117 0.245
Human
nitrogen compound transport GO:0071705 191 0.245
regulation of cell migration GO:0030334 289 0.242
neuron remodeling GO:0016322 2 0.239
ribonucleoside monophosphate metabolic process GO:0009161 187 0.235
purine nucleoside triphosphate metabolic process GO:0009144 412 0.234
positive regulation of interleukin 13 production GO:0032736 4 0.234
cellular carbohydrate catabolic process GO:0044275 17 0.233
carbohydrate catabolic process GO:0016052 36 0.231
negative regulation of cholesterol storage GO:0010887 4 0.225
nose development GO:0043584 2 0.225
ribonucleoside catabolic process GO:0042454 406 0.222
triglyceride metabolic process GO:0006641 23 0.221
regulation of receptor biosynthetic process GO:0010869 15 0.220
negative regulation of cell differentiation GO:0045596 171 0.218
positive regulation of programmed cell death GO:0043068 249 0.214
Human
ribonucleoside monophosphate catabolic process GO:0009158 158 0.213
cell morphogenesis involved in differentiation GO:0000904 144 0.213
nucleotide catabolic process GO:0009166 408 0.212
generation of neurons GO:0048699 152 0.212
response to organic cyclic compound GO:0014070 204 0.211
glucose homeostasis GO:0042593 31 0.211
Human
secretion by cell GO:0032940 226 0.210
regulation of t helper cell differentiation GO:0045622 3 0.210
regulation of secretion by cell GO:1903530 177 0.209
cytokine production GO:0001816 247 0.206
hormone secretion GO:0046879 65 0.204
negative regulation of cytokine production GO:0001818 82 0.203
humoral immune response GO:0006959 49 0.200
glycerolipid metabolic process GO:0046486 107 0.199
dna duplex unwinding GO:0032508 30 0.199
lipid localization GO:0010876 106 0.196
negative regulation of wnt signaling pathway GO:0030178 69 0.194
secretion GO:0046903 254 0.193
regulation of jnk cascade GO:0046328 73 0.193
regulation of body fluid levels GO:0050878 99 0.192
apoptotic signaling pathway GO:0097190 268 0.192
Human
determination of adult lifespan GO:0008340 2 0.191
alpha beta t cell differentiation GO:0046632 7 0.188
purine nucleotide catabolic process GO:0006195 405 0.187
cellular response to lipid GO:0071396 127 0.185
purine nucleoside catabolic process GO:0006152 398 0.185
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.185
negative regulation of jnk cascade GO:0046329 16 0.184
chromatin remodeling GO:0006338 55 0.180
peptide transport GO:0015833 74 0.179
cellular response to insulin stimulus GO:0032869 41 0.178
Human
negative regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0017055 2 0.176
positive regulation of cell proliferation GO:0008284 301 0.170
respiratory system development GO:0060541 22 0.170
dna geometric change GO:0032392 32 0.169
long term memory GO:0007616 2 0.167
cellular lipid metabolic process GO:0044255 303 0.165
Mouse Rat
hormone transport GO:0009914 68 0.162
nucleoside triphosphate metabolic process GO:0009141 422 0.162
regulation of defense response GO:0031347 154 0.161
Human
multicellular organismal aging GO:0010259 3 0.161
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.158
circulatory system development GO:0072359 262 0.157
Rat
lymphocyte activation GO:0046649 133 0.155
palate development GO:0060021 13 0.154
short term memory GO:0007614 1 0.153
chordate embryonic development GO:0043009 34 0.152
negative regulation of stress activated mapk cascade GO:0032873 19 0.151
growth hormone secretion GO:0030252 4 0.146
organophosphate catabolic process GO:0046434 430 0.144
purine containing compound catabolic process GO:0072523 411 0.144
regulation of dna templated transcription in response to stress GO:0043620 18 0.138
lactation GO:0007595 3 0.138
carboxylic acid biosynthetic process GO:0046394 97 0.136
Human
mapk cascade GO:0000165 288 0.136
chromatin organization GO:0006325 351 0.135
positive regulation of cellular component movement GO:0051272 181 0.132
regulation of cellular carbohydrate catabolic process GO:0043471 11 0.131
neutral lipid metabolic process GO:0006638 27 0.131
regulation of epithelial cell migration GO:0010632 93 0.130
intracellular estrogen receptor signaling pathway GO:0030520 23 0.129
neuron projection development GO:0031175 106 0.128
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.127
negative regulation of bile acid biosynthetic process GO:0070858 3 0.125
Human
camera type eye development GO:0043010 25 0.124
negative regulation of cell death GO:0060548 345 0.123
Rat
jnk cascade GO:0007254 80 0.122
definitive erythrocyte differentiation GO:0060318 2 0.122
regulation of t cell activation GO:0050863 77 0.122
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.121
acylglycerol metabolic process GO:0006639 27 0.121
epithelial cell differentiation GO:0030855 141 0.121
Human
blood circulation GO:0008015 113 0.120
Human Rat
regulation of stress activated mapk cascade GO:0032872 84 0.120
embryonic camera type eye development GO:0031076 2 0.118
eye development GO:0001654 42 0.118
purine nucleoside monophosphate metabolic process GO:0009126 186 0.118
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.117
regulation of lymphocyte activation GO:0051249 103 0.117
anion transport GO:0006820 161 0.116
response to extracellular stimulus GO:0009991 85 0.116
Human Mouse
regulation of peptidase activity GO:0052547 180 0.116
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.115
response to nitrogen compound GO:1901698 184 0.115
Human Rat
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 3 0.114
reproductive process GO:0022414 106 0.113
Human
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.113
cell cell signaling GO:0007267 155 0.113
stress activated protein kinase signaling cascade GO:0031098 94 0.112
generation of precursor metabolites and energy GO:0006091 68 0.111
lipid catabolic process GO:0016042 84 0.111
histone modification GO:0016570 251 0.111
morphogenesis of an epithelium GO:0002009 60 0.110
response to steroid hormone GO:0048545 80 0.110
lipid homeostasis GO:0055088 39 0.110
single organism reproductive process GO:0044702 98 0.110
Human
dna templated transcription initiation GO:0006352 35 0.109
regulation of generation of precursor metabolites and energy GO:0043467 27 0.108
cellular response to peptide hormone stimulus GO:0071375 56 0.108
Human
response to insulin GO:0032868 45 0.108
Human Rat
signal transduction by phosphorylation GO:0023014 297 0.107
regulation of smooth muscle cell proliferation GO:0048660 28 0.107
Human
morphogenesis of embryonic epithelium GO:0016331 4 0.106
regulation of peptide secretion GO:0002791 42 0.106
negative regulation of myotube differentiation GO:0010832 4 0.104
circulatory system process GO:0003013 113 0.102
Human Rat
positive regulation of cell migration GO:0030335 172 0.102
ovulation cycle GO:0042698 9 0.101
bile acid metabolic process GO:0008206 14 0.101
Human
reproductive system development GO:0061458 56 0.100
Human
regulation of growth GO:0040008 165 0.100
cellular response to peptide GO:1901653 59 0.100
Human
defense response GO:0006952 315 0.098
Human
regulation of alpha beta t cell differentiation GO:0046637 5 0.097
negative regulation of cellular component organization GO:0051129 235 0.097
response to peptide GO:1901652 65 0.096
Human Rat
regulation of proteolysis GO:0030162 293 0.096
Human
sprouting angiogenesis GO:0002040 29 0.096
wnt signaling pathway GO:0016055 156 0.096
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.096
cellular response to nutrient GO:0031670 12 0.096
Human
epithelium migration GO:0090132 119 0.096
regulation of leukocyte activation GO:0002694 115 0.095
steroid metabolic process GO:0008202 94 0.095
Human
negative regulation of developmental process GO:0051093 247 0.094
response to low density lipoprotein particle GO:0055098 4 0.093
Human
epithelial cell migration GO:0010631 119 0.093
positive regulation of endothelial cell migration GO:0010595 39 0.092
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.092
hexose metabolic process GO:0019318 55 0.092
Mouse
cellular homeostasis GO:0019725 196 0.091
cellular protein catabolic process GO:0044257 261 0.090
response to nutrient GO:0007584 20 0.090
Human
positive regulation of lymphocyte activation GO:0051251 73 0.089
protein dna complex subunit organization GO:0071824 80 0.088
negative regulation of intracellular signal transduction GO:1902532 183 0.088
monosaccharide metabolic process GO:0005996 74 0.088
Mouse
positive regulation of transcription from rna polymerase iii promoter GO:0045945 10 0.088
response to estradiol GO:0032355 23 0.087
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003256 3 0.086
regulation of cell motility GO:2000145 299 0.085
definitive hemopoiesis GO:0060216 2 0.083
chemotaxis GO:0006935 157 0.083
regulation of t helper 2 cell differentiation GO:0045628 1 0.082
regulation of neurogenesis GO:0050767 82 0.081
fatty acid metabolic process GO:0006631 115 0.080
Mouse Rat
t helper cell differentiation GO:0042093 4 0.079
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.078
Human
positive regulation of cell death GO:0010942 263 0.078
Human
regulation of triglyceride metabolic process GO:0090207 11 0.077
negative regulation of immune system process GO:0002683 136 0.077
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.077
response to growth factor GO:0070848 205 0.077
negative regulation of phosphorylation GO:0042326 174 0.076
regulation of wnt signaling pathway GO:0030111 123 0.076
regulation of ossification GO:0030278 58 0.075
positive regulation of growth GO:0045927 58 0.075
luteinization GO:0001553 2 0.075
cellular macromolecule catabolic process GO:0044265 380 0.073
protein maturation GO:0051604 233 0.072
Human
vesicle mediated transport GO:0016192 371 0.071
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.071
regulation of peptide transport GO:0090087 62 0.071
small molecule biosynthetic process GO:0044283 157 0.070
Human
appendage development GO:0048736 23 0.070
outflow tract septum morphogenesis GO:0003148 4 0.070
regulation of growth hormone secretion GO:0060123 3 0.069
negative regulation of stress activated protein kinase signaling cascade GO:0070303 19 0.068
oogenesis GO:0048477 2 0.067
negative regulation of apoptotic process GO:0043066 316 0.066
photoreceptor cell differentiation GO:0046530 2 0.066
regulation of cell activation GO:0050865 125 0.066
positive regulation of cell activation GO:0050867 81 0.066
positive regulation of leukocyte activation GO:0002696 80 0.065
smooth muscle cell migration GO:0014909 18 0.065
regulation of lipid transport GO:0032368 44 0.065
ear morphogenesis GO:0042471 7 0.065
growth GO:0040007 202 0.065
neurological system process GO:0050877 163 0.064
cell maturation GO:0048469 11 0.064
Human
cellular response to nitrogen compound GO:1901699 144 0.064
Human
branching morphogenesis of an epithelial tube GO:0048754 19 0.063
ossification GO:0001503 121 0.062
stress activated mapk cascade GO:0051403 93 0.062
blastocyst formation GO:0001825 3 0.061
response to estrogen GO:0043627 47 0.060
negative regulation of cellular amine metabolic process GO:0033239 3 0.060
cation transport GO:0006812 331 0.060
response to vitamin d GO:0033280 10 0.060
Human
regulation of cholesterol storage GO:0010885 8 0.060
tissue morphogenesis GO:0048729 96 0.060
protein catabolic process GO:0030163 325 0.059
positive regulation of transport GO:0051050 336 0.059
regulation of carbohydrate catabolic process GO:0043470 11 0.059
activation of innate immune response GO:0002218 55 0.058
head development GO:0060322 108 0.058
positive regulation of alpha beta t cell differentiation GO:0046638 4 0.057
regulation of nucleotide catabolic process GO:0030811 205 0.057
regulation of cell migration involved in sprouting angiogenesis GO:0090049 9 0.057
sterol homeostasis GO:0055092 28 0.056
face development GO:0060324 12 0.056
coagulation GO:0050817 78 0.056
positive regulation of cell development GO:0010720 92 0.056
protein modification by small protein conjugation GO:0032446 342 0.055
muscle cell proliferation GO:0033002 35 0.055
Human
ubiquitin dependent protein catabolic process GO:0006511 206 0.055
receptor metabolic process GO:0043112 81 0.054
regulation of cellular response to stress GO:0080135 244 0.054
response to peptide hormone GO:0043434 61 0.054
Human Rat
lipid modification GO:0030258 84 0.054
Mouse
response to external biotic stimulus GO:0043207 261 0.053
limbic system development GO:0021761 3 0.053
negative regulation of mapk cascade GO:0043409 56 0.052
alpha beta t cell differentiation involved in immune response GO:0002293 5 0.052
organelle assembly GO:0070925 176 0.052
embryonic morphogenesis GO:0048598 85 0.052
regulation of innate immune response GO:0045088 97 0.052
Human
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 9 0.052
response to molecule of bacterial origin GO:0002237 82 0.052
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.051
phosphatidylinositol mediated signaling GO:0048015 55 0.051
response to bacterium GO:0009617 144 0.050
oxidation reduction process GO:0055114 396 0.050
Human Mouse
positive regulation of protein sumoylation GO:0033235 7 0.050
developmental growth GO:0048589 48 0.050
lipid oxidation GO:0034440 33 0.050
Mouse
negative regulation of cellular component movement GO:0051271 106 0.050
intracellular receptor signaling pathway GO:0030522 104 0.050
positive regulation of interleukin 4 production GO:0032753 3 0.048
embryo development GO:0009790 123 0.048
cellular macromolecular complex assembly GO:0034622 324 0.048
positive regulation of defense response GO:0031349 87 0.048
regulation of organ growth GO:0046620 7 0.048
regulation of multi organism process GO:0043900 157 0.048
receptor biosynthetic process GO:0032800 18 0.048
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.047
viral life cycle GO:0019058 132 0.047
neuron fate commitment GO:0048663 2 0.047
hormone mediated signaling pathway GO:0009755 22 0.047
hindbrain development GO:0030902 3 0.047
steroid biosynthetic process GO:0006694 46 0.046
Human
response to alkaloid GO:0043279 20 0.046
Rat
organic acid biosynthetic process GO:0016053 97 0.046
Human
morphogenesis of a branching structure GO:0001763 21 0.046
cellular lipid catabolic process GO:0044242 65 0.045
microtubule cytoskeleton organization GO:0000226 176 0.045
post embryonic development GO:0009791 2 0.045
female gamete generation GO:0007292 2 0.045
intracellular protein transport GO:0006886 270 0.045
positive regulation of organelle organization GO:0010638 195 0.045
response to cocaine GO:0042220 1 0.044
regulation of leukocyte differentiation GO:1902105 61 0.044
organic hydroxy compound biosynthetic process GO:1901617 71 0.044
Human
regulation of transcription from rna polymerase iii promoter GO:0006359 13 0.044
positive regulation of apoptotic process GO:0043065 246 0.044
Human
negative regulation of protein metabolic process GO:0051248 391 0.044
transmembrane transport GO:0055085 399 0.043
drug catabolic process GO:0042737 10 0.043
Human
regulation of transcription involved in g2 m transition of mitotic cell cycle GO:0000117 1 0.043
cellular amino acid metabolic process GO:0006520 116 0.043
regulation of purine nucleotide metabolic process GO:1900542 264 0.043
cellular amine metabolic process GO:0044106 41 0.043
regulation of striated muscle cell differentiation GO:0051153 25 0.042
regionalization GO:0003002 29 0.042
regulation of developmental growth GO:0048638 30 0.042
divalent metal ion transport GO:0070838 152 0.042
hippocampus development GO:0021766 1 0.042
positive regulation of immune system process GO:0002684 283 0.042
glial cell migration GO:0008347 4 0.042
ion transmembrane transport GO:0034220 338 0.042
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.042
Human
regulation of locomotion GO:0040012 329 0.042
protein targeting to nucleus GO:0044744 104 0.041
organic anion transport GO:0015711 103 0.041
positive regulation of proteolysis GO:0045862 142 0.041
Human
sensory organ morphogenesis GO:0090596 21 0.041
regulation of protein maturation GO:1903317 150 0.040
nephric duct development GO:0072176 4 0.040
locomotory behavior GO:0007626 1 0.040
cellular response to molecule of bacterial origin GO:0071219 62 0.040
negative regulation of gliogenesis GO:0014014 3 0.040
regulation of intracellular transport GO:0032386 195 0.040
regulation of fat cell differentiation GO:0045598 23 0.040
embryonic placenta development GO:0001892 1 0.040
negative regulation of protein processing GO:0010955 142 0.039
innate immune response GO:0045087 178 0.039
Human
regulation of endopeptidase activity GO:0052548 170 0.039
Human
positive regulation of cytokine production GO:0001819 167 0.039
guanosine containing compound metabolic process GO:1901068 244 0.039
neuroblast proliferation GO:0007405 4 0.039
small molecule catabolic process GO:0044282 92 0.038
negative regulation of chromatin silencing GO:0031936 4 0.038
metal ion transport GO:0030001 272 0.038
positive regulation of cell cycle GO:0045787 140 0.038
regulation of cell growth GO:0001558 135 0.038
cd4 positive alpha beta t cell activation GO:0035710 6 0.038
xenobiotic transport GO:0042908 1 0.038
Human
positive regulation of t cell activation GO:0050870 54 0.038
positive regulation of chromatin modification GO:1903310 30 0.037
carbohydrate homeostasis GO:0033500 31 0.037
Human
gland development GO:0048732 48 0.037
protein localization to organelle GO:0033365 280 0.037
regulation of intracellular protein transport GO:0033157 123 0.037
positive regulation of cell differentiation GO:0045597 211 0.037
Human
positive regulation of peptidase activity GO:0010952 88 0.037
Human
connective tissue development GO:0061448 39 0.036
positive regulation of hydrolase activity GO:0051345 331 0.036
Human
cell projection organization GO:0030030 252 0.036
transmission of nerve impulse GO:0019226 11 0.036
divalent inorganic cation transport GO:0072511 158 0.036
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.035
positive regulation of epidermal cell differentiation GO:0045606 8 0.035
Human
regulation of nucleotide metabolic process GO:0006140 269 0.035
rho protein signal transduction GO:0007266 26 0.035
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.035
negative regulation of leukocyte differentiation GO:1902106 24 0.035
regulation of purine nucleotide catabolic process GO:0033121 205 0.035
cartilage condensation GO:0001502 1 0.035
cation transmembrane transport GO:0098655 238 0.035
fat cell differentiation GO:0045444 32 0.034
blastocyst development GO:0001824 3 0.034
peptidyl lysine modification GO:0018205 144 0.034
regulation of lymphocyte differentiation GO:0045619 22 0.034
activation of immune response GO:0002253 114 0.034
monocarboxylic acid biosynthetic process GO:0072330 67 0.034
Human
regulation of cellular component biogenesis GO:0044087 281 0.034
axonogenesis GO:0007409 31 0.034
tumor necrosis factor production GO:0032640 43 0.033
response to decreased oxygen levels GO:0036293 96 0.033
Rat
regulation of immune effector process GO:0002697 91 0.033
thymus development GO:0048538 3 0.033
microtubule based process GO:0007017 210 0.033
neuron projection morphogenesis GO:0048812 50 0.033
bile acid biosynthetic process GO:0006699 10 0.033
Human
positive regulation of leukocyte differentiation GO:1902107 37 0.032
regulation of system process GO:0044057 101 0.032
cation homeostasis GO:0055080 189 0.032
positive regulation of cellular component organization GO:0051130 376 0.032
small gtpase mediated signal transduction GO:0007264 78 0.032
spindle organization GO:0007051 53 0.032
mitotic cell cycle GO:0000278 326 0.032
zymogen activation GO:0031638 70 0.031
Human
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.031
Human
negative regulation of cell motility GO:2000146 104 0.031
peptidyl lysine deacetylation GO:0034983 6 0.031
response to biotic stimulus GO:0009607 276 0.031
positive regulation of lymphocyte differentiation GO:0045621 13 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.031
response to acid chemical GO:0001101 66 0.031
Human
pituitary gland development GO:0021983 2 0.030
negative regulation of alpha beta t cell activation GO:0046636 3 0.030
regulation of t cell differentiation GO:0045580 19 0.030
regulation of oxidoreductase activity GO:0051341 43 0.030
Human
peripheral nervous system development GO:0007422 2 0.030
myeloid leukocyte differentiation GO:0002573 60 0.030
Human
body fluid secretion GO:0007589 9 0.030
prostate gland development GO:0030850 3 0.030
regulation of protein localization GO:0032880 296 0.030
muscle tissue development GO:0060537 62 0.030
regulation of protein processing GO:0070613 150 0.030

PPARA disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.058
Human
musculoskeletal system disease DOID:17 223 0.043
Human
inherited metabolic disorder DOID:655 242 0.031