IMP

Process View

Homo sapiens

3 genes annotated in human

Multi-species View

lactation

GO:0007595

The secretion of milk by the mammary gland.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lactation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "lactation" (in gray)

Name	Description	Probability	Func Analog Organism
EGFR	epidermal growth factor receptor	0.995	Human
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.956	Human
GHR	growth hormone receptor	0.409
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.341	Human
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.313
CCND3	cyclin D3	0.305
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.302
PDZD11	PDZ domain containing 11	0.244
INSR	insulin receptor	0.217
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.190
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.163
RXRA	retinoid X receptor, alpha	0.146
PPARA	peroxisome proliferator-activated receptor alpha	0.138
RUNX1	runt-related transcription factor 1	0.108
NRP1	neuropilin 1	0.108
EPOR	erythropoietin receptor	0.105
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.082
PPP5C	protein phosphatase 5, catalytic subunit	0.074
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.070
DLG2	discs, large homolog 2 (Drosophila)	0.069
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.066
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.052
HR	hairless homolog (mouse)	0.048
MUC1	mucin 1, cell surface associated	0.047
ALDOA	aldolase A, fructose-bisphosphate	0.044
GAB1	GRB2-associated binding protein 1	0.043
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.043
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.042
PGR	progesterone receptor	0.041
CDK6	cyclin-dependent kinase 6	0.041
SP1	Sp1 transcription factor	0.041
ESR1	estrogen receptor 1	0.041
ESR2	estrogen receptor 2 (ER beta)	0.040
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.037
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.035	Mouse
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.035
PGF	placental growth factor	0.034
MTA2	metastasis associated 1 family, member 2	0.032
CAV2	caveolin 2	0.032
IL2RB	interleukin 2 receptor, beta	0.031
EPT1	ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)	0.031
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.031
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.031
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.030
IGF1R	insulin-like growth factor 1 receptor	0.029
USF1	upstream transcription factor 1	0.027
JAK2	Janus kinase 2	0.027
VAV2	vav 2 guanine nucleotide exchange factor	0.024
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.024
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.024
STAP2	signal transducing adaptor family member 2	0.024
BCL6	B-cell CLL/lymphoma 6	0.024
EGLN1	egl nine homolog 1 (C. elegans)	0.023
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.022
NCOA6	nuclear receptor coactivator 6	0.021
STAT5B	signal transducer and activator of transcription 5B	0.021	Mouse
PTPRF	protein tyrosine phosphatase, receptor type, F	0.020
TNS4	tensin 4	0.020
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.020
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.020
RFK	riboflavin kinase	0.020
NCOR2	nuclear receptor corepressor 2	0.019	Rat
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.018
LDLR	low density lipoprotein receptor	0.018
NCOA3	nuclear receptor coactivator 3	0.018
CALCA	calcitonin-related polypeptide alpha	0.018
EGF	epidermal growth factor	0.018
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.017
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.017
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.017
FKBP5	FK506 binding protein 5	0.017
PTK6	PTK6 protein tyrosine kinase 6	0.016
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.016
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.016
RANBP9	RAN binding protein 9	0.016
CCNE1	cyclin E1	0.016
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.016
DNAJC3	DnaJ (Hsp40) homolog, subfamily C, member 3	0.015
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.015
MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	0.015
VHL	von Hippel-Lindau tumor suppressor	0.015
SOCS4	suppressor of cytokine signaling 4	0.015
KAT2B	K(lysine) acetyltransferase 2B	0.015
PRL	prolactin	0.015
FRS2	fibroblast growth factor receptor substrate 2	0.014
NCOA1	nuclear receptor coactivator 1	0.014
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.014
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.014
NCOA2	nuclear receptor coactivator 2	0.014
MED29	mediator complex subunit 29	0.014
DDR2	discoidin domain receptor tyrosine kinase 2	0.014
TRO	trophinin	0.014
UBASH3B	ubiquitin associated and SH3 domain containing B	0.014
TGS1	trimethylguanosine synthase 1	0.014
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.014
BCAR1	breast cancer anti-estrogen resistance 1	0.013
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.013
RB1	retinoblastoma 1	0.013
CCND2	cyclin D2	0.012
STAT5A	signal transducer and activator of transcription 5A	0.012	Mouse Rat
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.012
NRG1	neuregulin 1	0.012
CDK8	cyclin-dependent kinase 8	0.012
MTA1	metastasis associated 1	0.012
AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.011
GAB2	GRB2-associated binding protein 2	0.011
EPAS1	endothelial PAS domain protein 1	0.011
EPRS	glutamyl-prolyl-tRNA synthetase	0.011
HDAC10	histone deacetylase 10	0.011
CDK2	cyclin-dependent kinase 2	0.011
CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1	0.011
MTA3	metastasis associated 1 family, member 3	0.011
SOCS1	suppressor of cytokine signaling 1	0.011
AKAP13	A kinase (PRKA) anchor protein 13	0.011
CISH	cytokine inducible SH2-containing protein	0.011
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.011
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.010
KIAA2026	KIAA2026	0.010
FOXO1	forkhead box O1	0.010
TNS3	tensin 3	0.010
GTF2I	general transcription factor IIi	0.010
EGLN3	egl nine homolog 3 (C. elegans)	0.010
UTP20	UTP20, small subunit (SSU) processome component, homolog (yeast)	0.010
AHR	aryl hydrocarbon receptor	0.010
BRAP	BRCA1 associated protein	0.010
APP	amyloid beta (A4) precursor protein	0.010