Mus musculus

14 known processes

Sgol1

shugoshin-like 1 (S. pombe)

(Aliases: MGC113769,C81037,3300001M08Rik,Sgo1)

Sgol1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome segregation GO:0007059 48 0.783
Human
mitotic cell cycle GO:0000278 195 0.776
organelle fission GO:0048285 170 0.730
Human
regulation of cell cycle GO:0051726 281 0.702
double strand break repair GO:0006302 48 0.657
nuclear division GO:0000280 158 0.656
Human
dna repair GO:0006281 107 0.647
regulation of chromosome segregation GO:0051983 21 0.622
cellular response to dna damage stimulus GO:0006974 207 0.602
dna metabolic process GO:0006259 303 0.576
mitotic sister chromatid cohesion GO:0007064 1 0.486
regulation of chromosome organization GO:0033044 83 0.475
meiotic nuclear division GO:0007126 115 0.463
Human
mitotic cell cycle process GO:1903047 159 0.456
regulation of nuclear division GO:0051783 56 0.437
regulation of mitosis GO:0007088 29 0.430
regulation of mitotic cell cycle phase transition GO:1901990 73 0.378
microtubule based process GO:0007017 236 0.362
regulation of cell cycle process GO:0010564 160 0.341
meiotic cell cycle GO:0051321 122 0.303
Human
male meiosis GO:0007140 37 0.300
cell division GO:0051301 120 0.287
microtubule cytoskeleton organization GO:0000226 157 0.285
protein catabolic process GO:0030163 221 0.266
ubiquitin dependent protein catabolic process GO:0006511 129 0.250
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.242
regulation of cell division GO:0051302 76 0.236
positive regulation of mitotic cell cycle GO:0045931 41 0.229
dna recombination GO:0006310 92 0.219
meiosis i GO:0007127 60 0.216
negative regulation of cell cycle phase transition GO:1901988 48 0.215
negative regulation of nuclear division GO:0051784 19 0.213
male gamete generation GO:0048232 285 0.206
regulation of organelle organization GO:0033043 289 0.199
regulation of cellular protein catabolic process GO:1903362 61 0.194
negative regulation of cellular component organization GO:0051129 194 0.184
regulation of cellular ketone metabolic process GO:0010565 66 0.178
mitotic nuclear division GO:0007067 48 0.167
meiotic dna repair synthesis GO:0000711 4 0.156
dna endoreduplication GO:0042023 4 0.156
germ cell development GO:0007281 185 0.142
regulation of metaphase anaphase transition of cell cycle GO:1902099 9 0.134
mitotic sister chromatid segregation GO:0000070 14 0.127
sister chromatid segregation GO:0000819 20 0.125
regulation of exit from mitosis GO:0007096 1 0.122
regulation of sister chromatid segregation GO:0033045 13 0.118
regulation of protein kinase activity GO:0045859 232 0.118
cellular amino acid metabolic process GO:0006520 103 0.115
response to radiation GO:0009314 165 0.114
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.114
chromosome separation GO:0051304 14 0.113
regulation of cellular amine metabolic process GO:0033238 20 0.111
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.110
regulation of mitotic sister chromatid segregation GO:0033047 12 0.103
modification dependent macromolecule catabolic process GO:0043632 133 0.100
cellular macromolecule catabolic process GO:0044265 206 0.098
negative regulation of ligase activity GO:0051352 3 0.096
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.096
regulation of mitotic cell cycle GO:0007346 126 0.094
mitotic sister chromatid separation GO:0051306 9 0.091
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.088
dna biosynthetic process GO:0071897 22 0.088
female meiosis chromosome segregation GO:0016321 1 0.087
lateral inhibition GO:0046331 1 0.087
regulation of protein catabolic process GO:0042176 108 0.087
positive regulation of cellular amine metabolic process GO:0033240 5 0.087
regulation of cell cycle phase transition GO:1901987 77 0.085
cellular protein catabolic process GO:0044257 155 0.085
protein maturation GO:0051604 176 0.085
immune effector process GO:0002252 321 0.083
regulation of proteasomal protein catabolic process GO:0061136 46 0.082
regulation of microtubule based process GO:0032886 52 0.080
cytokinesis GO:0000910 17 0.080
positive regulation of chromosome segregation GO:0051984 4 0.080
nucleoside metabolic process GO:0009116 246 0.079
cellular amine metabolic process GO:0044106 44 0.077
meiotic cell cycle process GO:1903046 77 0.077
Human
modification dependent protein catabolic process GO:0019941 133 0.076
macromolecule catabolic process GO:0009057 281 0.076
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.076
positive regulation of cell cycle GO:0045787 92 0.075
regulation of protein processing GO:0070613 96 0.075
regulation of cellular amino acid metabolic process GO:0006521 5 0.074
negative regulation of cell cycle GO:0045786 123 0.074
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.073
negative regulation of organelle organization GO:0010639 90 0.072
adaptive immune response GO:0002250 155 0.071
cell fate commitment GO:0045165 210 0.069
centriole assembly GO:0098534 6 0.066
proteasomal protein catabolic process GO:0010498 98 0.064
intrinsic apoptotic signaling pathway GO:0097193 132 0.064
negative regulation of proteolysis GO:0045861 74 0.060
organelle assembly GO:0070925 177 0.060
regulation of microtubule cytoskeleton organization GO:0070507 37 0.059
negative regulation of protein processing GO:0010955 79 0.059
negative regulation of protein catabolic process GO:0042177 36 0.058
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.058
reciprocal meiotic recombination GO:0007131 16 0.057
cellular ketone metabolic process GO:0042180 84 0.056
negative regulation of mitotic cell cycle GO:0045930 58 0.056
regulation of mitotic sister chromatid separation GO:0010965 12 0.055
centrosome organization GO:0051297 26 0.055
amine metabolic process GO:0009308 45 0.054
peptidyl lysine modification GO:0018205 77 0.054
organonitrogen compound catabolic process GO:1901565 264 0.053
negative regulation of protein metabolic process GO:0051248 282 0.052
nucleoside phosphate catabolic process GO:1901292 222 0.052
metaphase plate congression GO:0051310 2 0.051
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.049
multicellular organism growth GO:0035264 161 0.048
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.048
negative regulation of cell cycle process GO:0010948 69 0.048
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.047
purine containing compound catabolic process GO:0072523 213 0.047
regulation of proteolysis GO:0030162 164 0.046
glycosyl compound metabolic process GO:1901657 246 0.046
positive regulation of protein modification process GO:0031401 299 0.046
stem cell development GO:0048864 219 0.046
macromolecule methylation GO:0043414 120 0.046
purine nucleoside catabolic process GO:0006152 205 0.046
microtubule organizing center organization GO:0031023 28 0.045
lymphocyte mediated immunity GO:0002449 139 0.043
glycosyl compound catabolic process GO:1901658 206 0.042
maintenance of location GO:0051235 89 0.041
Human
chromatin modification GO:0016568 187 0.041
protein modification by small protein conjugation or removal GO:0070647 207 0.041
centrosome cycle GO:0007098 23 0.041
regulation of protein localization GO:0032880 231 0.041
purine nucleotide metabolic process GO:0006163 302 0.041
chromatin organization GO:0006325 206 0.041
sister chromatid cohesion GO:0007062 12 0.040
oogenesis GO:0048477 56 0.040
nucleobase containing small molecule metabolic process GO:0055086 352 0.039
positive regulation of cell cycle phase transition GO:1901989 17 0.039
regulation of dendritic cell cytokine production GO:0002730 2 0.039
positive regulation of mitotic metaphase anaphase transition GO:0045842 2 0.039
regulation of protein maturation GO:1903317 96 0.038
leukocyte differentiation GO:0002521 342 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.038
regulation of adaptive immune response GO:0002819 90 0.038
nucleoside triphosphate metabolic process GO:0009141 230 0.038
production of molecular mediator of immune response GO:0002440 103 0.037
isotype switching GO:0045190 36 0.036
female gamete generation GO:0007292 74 0.036
histone h3 k9 dimethylation GO:0036123 4 0.035
positive regulation of chromosome organization GO:2001252 33 0.035
regulation of cell size GO:0008361 72 0.035
stem cell maintenance GO:0019827 130 0.035
spermatogenesis GO:0007283 284 0.035
protein localization to organelle GO:0033365 185 0.034
nucleotide metabolic process GO:0009117 332 0.034
establishment of spindle localization GO:0051293 19 0.034
response to light stimulus GO:0009416 135 0.034
negative regulation of cell division GO:0051782 24 0.033
negative regulation of mitotic sister chromatid segregation GO:0033048 7 0.033
establishment of organelle localization GO:0051656 122 0.033
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.032
g1 s transition of mitotic cell cycle GO:0000082 57 0.032
cell activation involved in immune response GO:0002263 126 0.032
regulation of cellular component size GO:0032535 121 0.032
organelle localization GO:0051640 179 0.032
response to ionizing radiation GO:0010212 42 0.032
nucleoside catabolic process GO:0009164 206 0.032
negative regulation of mitosis GO:0045839 10 0.032
regulation of histone methylation GO:0031060 30 0.032
spindle assembly involved in mitosis GO:0090307 4 0.032
gland development GO:0048732 330 0.032
negative regulation of cellular protein catabolic process GO:1903363 22 0.031
organophosphate catabolic process GO:0046434 232 0.031
positive regulation of protein catabolic process GO:0045732 60 0.030
centrosome duplication GO:0051298 16 0.030
protein modification by small protein conjugation GO:0032446 187 0.030
organic cyclic compound catabolic process GO:1901361 295 0.030
lymphocyte differentiation GO:0030098 242 0.030
mitotic cytokinesis GO:0000281 4 0.030
purine containing compound metabolic process GO:0072521 311 0.030
negative regulation of cell size GO:0045792 3 0.029
b cell activation GO:0042113 161 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
stem cell differentiation GO:0048863 268 0.029
histone modification GO:0016570 159 0.028
negative regulation of sister chromatid segregation GO:0033046 7 0.028
negative regulation of mitotic sister chromatid separation GO:2000816 7 0.028
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 9 0.028
methylation GO:0032259 134 0.028
t cell activation GO:0042110 289 0.028
positive regulation of apoptotic process GO:0043065 217 0.027
positive regulation of lymphocyte activation GO:0051251 140 0.027
somatic stem cell maintenance GO:0035019 47 0.027
negative regulation of protein maturation GO:1903318 79 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
placenta development GO:0001890 140 0.026
purine nucleoside triphosphate catabolic process GO:0009146 203 0.026
positive regulation of cell development GO:0010720 237 0.026
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
endomembrane system organization GO:0010256 147 0.026
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
spindle localization GO:0051653 22 0.025
apoptotic signaling pathway GO:0097190 306 0.025
meiosis ii GO:0007135 7 0.025
cell cycle checkpoint GO:0000075 47 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.025
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 1 0.025
dna replication GO:0006260 52 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
translesion synthesis GO:0019985 1 0.025
spindle assembly involved in meiosis GO:0090306 4 0.025
blood vessel morphogenesis GO:0048514 285 0.024
mitotic spindle checkpoint GO:0071174 9 0.024
regulation of chromatin organization GO:1902275 57 0.024
epithelial tube morphogenesis GO:0060562 303 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.024
leukocyte mediated immunity GO:0002443 174 0.024
regulation of cellular response to stress GO:0080135 159 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.023
negative regulation of cellular catabolic process GO:0031330 47 0.023
establishment of spindle orientation GO:0051294 15 0.023
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.023
regulation of cell activation GO:0050865 289 0.023
immunoglobulin mediated immune response GO:0016064 69 0.023
somatic cell dna recombination GO:0016444 51 0.023
protein ubiquitination GO:0016567 171 0.023
cell adhesion GO:0007155 329 0.023
regulation of cytoskeleton organization GO:0051493 122 0.023
mitotic chromosome condensation GO:0007076 1 0.022
wnt signaling pathway GO:0016055 188 0.022
alpha beta t cell activation GO:0046631 91 0.022
membrane organization GO:0061024 245 0.021
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.021
neuroblast fate commitment GO:0014017 1 0.021
protein methylation GO:0006479 81 0.021
folic acid containing compound metabolic process GO:0006760 3 0.021
regulation of mitotic metaphase anaphase transition GO:0030071 8 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
rho protein signal transduction GO:0007266 32 0.020
heterocycle catabolic process GO:0046700 280 0.020
positive regulation of cell death GO:0010942 224 0.020
leukocyte activation involved in immune response GO:0002366 126 0.020
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.020
mitotic spindle assembly checkpoint GO:0007094 7 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
liver development GO:0001889 66 0.020
nucleotide catabolic process GO:0009166 217 0.020
histone threonine phosphorylation GO:0035405 1 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
cellular response to abiotic stimulus GO:0071214 56 0.019
regulation of anatomical structure size GO:0090066 178 0.019
negative regulation of chromosome organization GO:2001251 30 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
positive regulation of cell cycle process GO:0090068 61 0.018
cell type specific apoptotic process GO:0097285 268 0.018
regulation of t cell activation GO:0050863 170 0.018
covalent chromatin modification GO:0016569 163 0.018
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 8 0.018
regulation of response to wounding GO:1903034 189 0.018
spindle checkpoint GO:0031577 12 0.018
aromatic compound catabolic process GO:0019439 286 0.018
negative regulation of neuron differentiation GO:0045665 101 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
histone methylation GO:0016571 71 0.018
cell cycle arrest GO:0007050 37 0.017
stem cell fate determination GO:0048867 2 0.017
alpha beta t cell differentiation GO:0046632 69 0.017
intracellular mrna localization GO:0008298 4 0.017
response to organonitrogen compound GO:0010243 246 0.017
cell fate specification GO:0001708 72 0.017
regulation of lymphocyte mediated immunity GO:0002706 84 0.017
response to camptothecin GO:1901563 1 0.017
response to uv GO:0009411 44 0.017
regulation of actin filament based process GO:0032970 99 0.017
male meiosis i GO:0007141 16 0.017
ras protein signal transduction GO:0007265 77 0.017
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
response to hydroperoxide GO:0033194 6 0.016
positive regulation of histone h3 k9 methylation GO:0051574 4 0.016
spindle assembly involved in female meiosis GO:0007056 3 0.016
protein processing GO:0016485 163 0.016
histone h3 acetylation GO:0043966 14 0.016
response to gamma radiation GO:0010332 22 0.016
centriole replication GO:0007099 5 0.016
regulation of neuron differentiation GO:0045664 281 0.016
response to alkaloid GO:0043279 34 0.016
peptidyl amino acid modification GO:0018193 336 0.015
rhythmic process GO:0048511 174 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
regulation of histone modification GO:0031056 56 0.015
regulation of homeostatic process GO:0032844 182 0.015
b cell mediated immunity GO:0019724 71 0.015
establishment of mitotic spindle orientation GO:0000132 12 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
cell fate determination GO:0001709 32 0.015
signal transduction by p53 class mediator GO:0072331 51 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
cellular homeostasis GO:0019725 240 0.015
negative regulation of chromosome segregation GO:0051985 9 0.015
regulation of asymmetric cell division GO:0009786 4 0.015
protein polymerization GO:0051258 57 0.014
regulation of cytokine production GO:0001817 266 0.014
neuroblast fate determination GO:0007400 1 0.014
chromatin assembly or disassembly GO:0006333 16 0.014
oxidation reduction process GO:0055114 342 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
positive regulation of organelle organization GO:0010638 128 0.014
regulation of dna recombination GO:0000018 34 0.014
microtubule polymerization or depolymerization GO:0031109 26 0.014
forebrain development GO:0030900 302 0.014
female meiotic division GO:0007143 21 0.014
endocytosis GO:0006897 168 0.014
regulation of leukocyte mediated immunity GO:0002703 104 0.014
mitotic recombination GO:0006312 3 0.013
digestive system development GO:0055123 200 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
regulation of transferase activity GO:0051338 263 0.013
cellularization GO:0007349 1 0.013
positive regulation of immune effector process GO:0002699 107 0.013
cation transport GO:0006812 399 0.013
histone lysine methylation GO:0034968 50 0.013
mesodermal cell migration GO:0008078 4 0.013
spindle organization GO:0007051 28 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
spindle assembly GO:0051225 13 0.013
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 2 0.013
development of primary sexual characteristics GO:0045137 143 0.013
negative regulation of protein modification process GO:0031400 163 0.013
leukocyte proliferation GO:0070661 172 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
striated muscle tissue development GO:0014706 293 0.013
actin cytoskeleton organization GO:0030036 220 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
cell maturation GO:0048469 127 0.012
myosin filament assembly GO:0031034 2 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
nucleoside monophosphate catabolic process GO:0009125 59 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
mitotic spindle organization GO:0007052 10 0.012
myeloid cell differentiation GO:0030099 233 0.012
protein acylation GO:0043543 64 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
negative regulation of cell development GO:0010721 169 0.012
regulation of cell shape GO:0008360 39 0.012
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.012
negative regulation of mitotic metaphase anaphase transition GO:0045841 7 0.012
peptidyl lysine methylation GO:0018022 29 0.012
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.012
response to acid chemical GO:0001101 111 0.012
positive regulation of t cell activation GO:0050870 101 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
regulation of kinase activity GO:0043549 249 0.011
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
regulation of histone h3 k4 methylation GO:0051569 12 0.011
circulatory system process GO:0003013 197 0.011
regulation of protein complex assembly GO:0043254 83 0.011
digestive tract development GO:0048565 190 0.011
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.011
response to organic cyclic compound GO:0014070 198 0.011
centrosome separation GO:0051299 4 0.011
protein secretion GO:0009306 111 0.011
cell cycle g2 m phase transition GO:0044839 20 0.011
negative regulation of meiotic cell cycle phase transition GO:1901994 3 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.011
double strand break repair via homologous recombination GO:0000724 21 0.011
cellular protein complex assembly GO:0043623 116 0.011
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 3 0.011
positive regulation of cell activation GO:0050867 158 0.011
heterochromatin organization GO:0070828 4 0.011
regulation of chromatin modification GO:1903308 57 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
protein oligomerization GO:0051259 67 0.010
somatic diversification of immune receptors GO:0002200 53 0.010
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.010
muscle cell differentiation GO:0042692 261 0.010
negative regulation of transferase activity GO:0051348 85 0.010
neural tube formation GO:0001841 108 0.010
positive regulation of nuclear division GO:0051785 27 0.010
telencephalon development GO:0021537 186 0.010
hepaticobiliary system development GO:0061008 67 0.010
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.010
regulation of meiotic cell cycle phase transition GO:1901993 3 0.010
gonad development GO:0008406 141 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
mapk cascade GO:0000165 281 0.010

Sgol1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.228
cancer DOID:162 0 0.189
thoracic cancer DOID:5093 0 0.142
organ system cancer DOID:0050686 0 0.142
breast cancer DOID:1612 0 0.087
immune system disease DOID:2914 0 0.045
disease of anatomical entity DOID:7 0 0.045
disease of metabolism DOID:0014667 0 0.036
inherited metabolic disorder DOID:655 0 0.036
hematopoietic system disease DOID:74 0 0.030
physical disorder DOID:0080015 0 0.019
congenital nervous system abnormality DOID:2490 0 0.019
immune system cancer DOID:0060083 0 0.017
gastrointestinal system cancer DOID:3119 0 0.016
intestinal cancer DOID:10155 0 0.016
congenital hypoplastic anemia DOID:1342 0 0.013
aplastic anemia DOID:12449 0 0.013
fanconi s anemia DOID:13636 0 0.013
bone marrow disease DOID:4961 0 0.013
anemia DOID:2355 0 0.013
reproductive organ cancer DOID:193 0 0.010