IMP
Process View
reciprocal meiotic recombination
The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "reciprocal meiotic recombination"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Brca1 | breast cancer 1 | 0.982 | ||
| Brca2 | breast cancer 2 | 0.917 | ||
| Pten | phosphatase and tensin homolog | 0.664 | ||
| Mcm3 | minichromosome maintenance deficient 3 (S. cerevisiae) | 0.515 | ||
| Cdca5 | cell division cycle associated 5 | 0.499 | ||
| Nde1 | nuclear distribution gene E homolog 1 (A nidulans) | 0.304 | ||
| Kif22 | kinesin family member 22 | 0.191 | ||
| Mcm4 | minichromosome maintenance deficient 4 homolog (S. cerevisiae) | 0.170 | ||
| Exo1 | exonuclease 1 | 0.168 | ||
| Trp53 | transformation related protein 53 | 0.167 | Fly | |
| Nup85 | nucleoporin 85 | 0.153 | ||
| Smc1a | structural maintenance of chromosomes 1A | 0.134 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.128 | ||
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.103 | ||
| Plk1 | polo-like kinase 1 (Drosophila) | 0.097 | Yeast | |
| Mybl2 | myeloblastosis oncogene-like 2 | 0.094 | ||
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.093 | ||
| Prim1 | DNA primase, p49 subunit | 0.090 | ||
| Ndel1 | nuclear distribution gene E-like homolog 1 (A. nidulans) | 0.089 | ||
| Mcm2 | minichromosome maintenance deficient 2 mitotin (S. cerevisiae) | 0.087 | ||
| Hells | helicase, lymphoid specific | 0.081 | ||
| Asf1b | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.079 | ||
| Rrm1 | ribonucleotide reductase M1 | 0.077 | ||
| Lig1 | ligase I, DNA, ATP-dependent | 0.076 | ||
| Wdhd1 | WD repeat and HMG-box DNA binding protein 1 | 0.071 | ||
| Ccne1 | cyclin E1 | 0.070 | ||
| Uhrf1 | ubiquitin-like, containing PHD and RING finger domains, 1 | 0.070 | ||
| Ccnf | cyclin F | 0.065 | ||
| Atm | ataxia telangiectasia mutated homolog (human) | 0.064 | ||
| Tacc3 | transforming, acidic coiled-coil containing protein 3 | 0.058 | ||
| Rfc1 | replication factor C (activator 1) 1 | 0.058 | ||
| Pole2 | polymerase (DNA directed), epsilon 2 (p59 subunit) | 0.057 | ||
| Sgol1 | shugoshin-like 1 (S. pombe) | 0.057 | ||
| Pms2 | postmeiotic segregation increased 2 (S. cerevisiae) | 0.055 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.054 | ||
| Nek2 | NIMA (never in mitosis gene a)-related expressed kinase 2 | 0.054 | ||
| Dlgap5 | discs, large (Drosophila) homolog-associated protein 5 | 0.051 | ||
| Orc1 | origin recognition complex, subunit 1 | 0.050 | ||
| Nbn | nibrin | 0.050 | ||
| Blm | Bloom syndrome, RecQ helicase-like | 0.050 | Worm Fly | |
| Kif23 | kinesin family member 23 | 0.050 | ||
| Aurka | aurora kinase A | 0.048 | ||
| Rad51ap1 | RAD51 associated protein 1 | 0.048 | ||
| Ccna2 | cyclin A2 | 0.048 | ||
| Bard1 | BRCA1 associated RING domain 1 | 0.047 | ||
| Ttk | Ttk protein kinase | 0.047 | ||
| Mcm7 | minichromosome maintenance deficient 7 (S. cerevisiae) | 0.047 | ||
| Fen1 | flap structure specific endonuclease 1 | 0.045 | ||
| Prc1 | protein regulator of cytokinesis 1 | 0.044 | ||
| Kif11 | kinesin family member 11 | 0.044 | ||
| Gtse1 | G two S phase expressed protein 1 | 0.044 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.042 | ||
| Aurkb | aurora kinase B | 0.042 | ||
| Atrx | alpha thalassemia/mental retardation syndrome X-linked homolog (human) | 0.042 | ||
| Ncaph | non-SMC condensin I complex, subunit H | 0.041 | ||
| Prim2 | DNA primase, p58 subunit | 0.041 | ||
| Fam54a | family with sequence similarity 54, member A | 0.041 | ||
| Trp73 | transformation related protein 73 | 0.040 | Fly | |
| Smc2 | structural maintenance of chromosomes 2 | 0.040 | ||
| Kif2c | kinesin family member 2C | 0.038 | ||
| Apc | adenomatosis polyposis coli | 0.037 | ||
| Kif20a | kinesin family member 20A | 0.036 | ||
| Trp63 | transformation related protein 63 | 0.036 | Fly | |
| Mecp2 | methyl CpG binding protein 2 | 0.035 | ||
| Dtl | denticleless homolog (Drosophila) | 0.035 | ||
| Cdc7 | cell division cycle 7 (S. cerevisiae) | 0.035 | ||
| Ccnb1 | cyclin B1 | 0.035 | ||
| Cdc20 | cell division cycle 20 homolog (S. cerevisiae) | 0.034 | ||
| Cdk1 | cyclin-dependent kinase 1 | 0.034 | ||
| Nxf2 | nuclear RNA export factor 2 | 0.034 | ||
| Cdc45 | cell division cycle 45 homolog (S. cerevisiae) | 0.034 | ||
| Bub1b | budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) | 0.033 | ||
| Gins1 | GINS complex subunit 1 (Psf1 homolog) | 0.033 | ||
| Tcf19 | transcription factor 19 | 0.033 | ||
| Cdc25c | cell division cycle 25 homolog C (S. pombe) | 0.031 | ||
| Dhfr | dihydrofolate reductase | 0.031 | ||
| Rfc4 | replication factor C (activator 1) 4 | 0.030 | ||
| Cenph | centromere protein H | 0.030 | ||
| E2f1 | E2F transcription factor 1 | 0.029 | ||
| Cdc6 | cell division cycle 6 homolog (S. cerevisiae) | 0.029 | ||
| Iqgap3 | IQ motif containing GTPase activating protein 3 | 0.028 | ||
| Bub1 | budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) | 0.028 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.027 | ||
| Psmc3ip | proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein | 0.027 | ||
| Stil | Scl/Tal1 interrupting locus | 0.026 | ||
| Ckap2 | cytoskeleton associated protein 2 | 0.025 | ||
| Spag5 | sperm associated antigen 5 | 0.025 | ||
| Cdkn2a | cyclin-dependent kinase inhibitor 2A | 0.023 | ||
| Incenp | inner centromere protein | 0.023 | ||
| Mis18bp1 | MIS18 binding protein 1 | 0.023 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.023 | ||
| Phf5a | PHD finger protein 5A | 0.022 | ||
| Cenpn | centromere protein N | 0.022 | ||
| Pola1 | polymerase (DNA directed), alpha 1 | 0.022 | ||
| Sass6 | spindle assembly 6 homolog (C. elegans) | 0.021 | ||
| Sfn | stratifin | 0.020 | ||
| Pask | PAS domain containing serine/threonine kinase | 0.020 | ||
| Racgap1 | Rac GTPase-activating protein 1 | 0.020 | ||
| Smc1b | structural maintenance of chromosomes 1B | 0.020 | ||
| Mcm10 | minichromosome maintenance deficient 10 (S. cerevisiae) | 0.019 | ||
| Anln | anillin, actin binding protein | 0.019 | ||
| Mnd1 | meiotic nuclear divisions 1 homolog (S. cerevisiae) | 0.019 | ||
| Cdca8 | cell division cycle associated 8 | 0.019 | ||
| Mcm5 | minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 0.019 | Fly | |
| Cdt1 | chromatin licensing and DNA replication factor 1 | 0.019 | ||
| Nusap1 | nucleolar and spindle associated protein 1 | 0.018 | ||
| Plk4 | polo-like kinase 4 (Drosophila) | 0.018 | ||
| Sae1 | SUMO1 activating enzyme subunit 1 | 0.018 | ||
| Cdca7 | cell division cycle associated 7 | 0.018 | ||
| Rad50 | RAD50 homolog (S. cerevisiae) | 0.018 | ||
| Pole | polymerase (DNA directed), epsilon | 0.018 | ||
| Fancd2 | Fanconi anemia, complementation group D2 | 0.017 | ||
| Mgea5 | meningioma expressed antigen 5 (hyaluronidase) | 0.017 | ||
| Diap3 | diaphanous homolog 3 (Drosophila) | 0.016 | ||
| Csde1 | cold shock domain containing E1, RNA binding | 0.016 | ||
| Chek1 | checkpoint kinase 1 homolog (S. pombe) | 0.016 | ||
| Cenpm | centromere protein M | 0.016 | ||
| Gsg2 | germ cell-specific gene 2 | 0.016 | ||
| Dnajc9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | 0.016 | ||
| Xrcc6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.015 | ||
| Recql4 | RecQ protein-like 4 | 0.015 | ||
| Ccdc99 | coiled-coil domain containing 99 | 0.015 | ||
| Cdk2 | cyclin-dependent kinase 2 | 0.015 | ||
| Haus5 | HAUS augmin-like complex, subunit 5 | 0.014 | ||
| BC055324 | cDNA sequence BC055324 | 0.014 | ||
| Rcc1 | regulator of chromosome condensation 1 | 0.014 | ||
| Cdca7l | cell division cycle associated 7 like | 0.014 | ||
| Cenpk | centromere protein K | 0.014 | ||
| Rrm2 | ribonucleotide reductase M2 | 0.014 | ||
| C330027C09Rik | RIKEN cDNA C330027C09 gene | 0.014 | ||
| Oip5 | Opa interacting protein 5 | 0.014 | ||
| Foxp3 | forkhead box P3 | 0.014 | ||
| Arid4b | AT rich interactive domain 4B (RBP1-like) | 0.013 | ||
| Mms22l | MMS22-like, DNA repair protein | 0.013 | ||
| Stag3 | stromal antigen 3 | 0.013 | ||
| E130303B06Rik | RIKEN cDNA E130303B06 gene | 0.013 | ||
| Rfc5 | replication factor C (activator 1) 5 | 0.013 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.013 | ||
| Mlh1 | mutL homolog 1 (E. coli) | 0.013 | ||
| Eif4a2 | eukaryotic translation initiation factor 4A2 | 0.013 | ||
| Foxm1 | forkhead box M1 | 0.013 | ||
| Mre11a | meiotic recombination 11 homolog A (S. cerevisiae) | 0.013 | Yeast | |
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.013 | ||
| Rfc2 | replication factor C (activator 1) 2 | 0.013 | ||
| Tk1 | thymidine kinase 1 | 0.013 | ||
| Amhr2 | anti-Mullerian hormone type 2 receptor | 0.012 | ||
| Dna2 | DNA replication helicase 2 homolog (yeast) | 0.012 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.012 | ||
| Tex14 | testis expressed gene 14 | 0.012 | ||
| Ssrp1 | structure specific recognition protein 1 | 0.012 | ||
| Msh2 | mutS homolog 2 (E. coli) | 0.012 | ||
| Parp1 | poly (ADP-ribose) polymerase family, member 1 | 0.012 | ||
| Ezh2 | enhancer of zeste homolog 2 (Drosophila) | 0.012 | ||
| 4930547N16Rik | RIKEN cDNA 4930547N16 gene | 0.012 | ||
| Syce1 | synaptonemal complex central element protein 1 | 0.012 | ||
| Rad18 | RAD18 homolog (S. cerevisiae) | 0.012 | ||
| Zfp42 | zinc finger protein 42 | 0.011 | ||
| Cdx2 | caudal type homeobox 2 | 0.011 | ||
| Mapk8 | mitogen-activated protein kinase 8 | 0.011 | ||
| Ndc80 | NDC80 homolog, kinetochore complex component (S. cerevisiae) | 0.011 | ||
| Atrip | ATR interacting protein | 0.011 | ||
| Tyms | thymidylate synthase | 0.011 | ||
| Lrr1 | leucine rich repeat protein 1 | 0.011 | ||
| Ubr7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.011 | ||
| Slmap | sarcolemma associated protein | 0.011 | ||
| Topbp1 | topoisomerase (DNA) II binding protein 1 | 0.010 | ||
| Tipin | timeless interacting protein | 0.010 | ||
| Mns1 | meiosis-specific nuclear structural protein 1 | 0.010 | ||
| Ckap5 | cytoskeleton associated protein 5 | 0.010 |