Mus musculus

103 known processes

Col1a1

collagen, type I, alpha 1

(Aliases: Col1a-1,Mov13,Cola-1,Cola1,Mov-13)

Col1a1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
extrinsic apoptotic signaling pathway GO:0097191 126 1.000
Mouse
endochondral bone morphogenesis GO:0060350 50 1.000
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 1.000
Mouse
cellular response to amino acid stimulus GO:0071230 29 1.000
connective tissue development GO:0061448 179 1.000
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 1.000
Mouse
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 1.000
bone development GO:0060348 120 0.999
chondrocyte differentiation GO:0002062 72 0.999
Mouse
response to amino acid GO:0043200 37 0.999
skeletal system morphogenesis GO:0048705 203 0.998
cartilage condensation GO:0001502 18 0.998
Mouse
extracellular structure organization GO:0043062 148 0.998
Human Mouse
proteoglycan metabolic process GO:0006029 38 0.997
Mouse
replacement ossification GO:0036075 26 0.997
positive regulation of ras protein signal transduction GO:0046579 13 0.997
Mouse
skeletal system development GO:0001501 356 0.996
bone morphogenesis GO:0060349 78 0.996
smooth muscle tissue development GO:0048745 22 0.995
Mouse
signal transduction in absence of ligand GO:0038034 55 0.995
Mouse
aorta morphogenesis GO:0035909 22 0.995
Mouse
negative regulation of cell motility GO:2000146 61 0.994
Mouse
embryonic skeletal system development GO:0048706 120 0.994
Human Mouse
regulation of cell migration GO:0030334 219 0.994
Human Mouse
lung development GO:0030324 164 0.993
ossification GO:0001503 216 0.992
skin development GO:0043588 220 0.992
face morphogenesis GO:0060325 29 0.992
appendage development GO:0048736 166 0.991
Zebrafish Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.991
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.989
embryonic organ morphogenesis GO:0048562 276 0.989
Mouse
digestive tract development GO:0048565 190 0.988
Mouse
cartilage development GO:0051216 140 0.986
cellular response to growth factor stimulus GO:0071363 197 0.983
Mouse Rat
negative regulation of endothelial cell proliferation GO:0001937 8 0.983
negative regulation of apoptotic signaling pathway GO:2001234 104 0.983
Mouse
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.982
cell aggregation GO:0098743 18 0.982
Mouse
body morphogenesis GO:0010171 45 0.980
protein heterooligomerization GO:0051291 14 0.979
bone trabecula formation GO:0060346 9 0.975
head morphogenesis GO:0060323 34 0.975
hair follicle morphogenesis GO:0031069 29 0.974
extracellular matrix organization GO:0030198 147 0.972
Human Mouse
multicellular organismal homeostasis GO:0048871 164 0.971
Mouse
hair cycle GO:0042633 90 0.971
odontogenesis GO:0042476 78 0.968
Human Rat
regulation of angiogenesis GO:0045765 81 0.967
limb bud formation GO:0060174 10 0.967
Mouse
negative regulation of cell migration GO:0030336 59 0.966
Mouse
growth plate cartilage development GO:0003417 14 0.962
striated muscle tissue development GO:0014706 293 0.958
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.957
response to organonitrogen compound GO:0010243 246 0.951
palate development GO:0060021 76 0.949
Mouse
molting cycle GO:0042303 90 0.947
cell adhesion GO:0007155 329 0.945
protein heterotrimerization GO:0070208 8 0.945
cardiac muscle tissue morphogenesis GO:0055008 44 0.942
Mouse
regulation of smad protein import into nucleus GO:0060390 3 0.938
artery development GO:0060840 53 0.937
Mouse
formation of radial glial scaffolds GO:0021943 4 0.936
cellular response to acid chemical GO:0071229 68 0.935
cellular response to organonitrogen compound GO:0071417 145 0.935
response to organic cyclic compound GO:0014070 198 0.931
Rat
regulation of cell motility GO:2000145 236 0.930
Human Mouse
cardiac muscle cell development GO:0055013 39 0.930
wound healing GO:0042060 157 0.929
Zebrafish Rat
face development GO:0060324 38 0.927
regulation of cellular amine metabolic process GO:0033238 20 0.921
cellular response to bmp stimulus GO:0071773 14 0.920
Mouse
cellular response to external stimulus GO:0071496 88 0.919
respiratory tube development GO:0030323 167 0.917
apoptotic signaling pathway GO:0097190 306 0.914
Mouse
prostate gland morphogenesis GO:0060512 32 0.913
protein catabolic process GO:0030163 221 0.908
mitotic cell cycle arrest GO:0071850 4 0.905
bone resorption GO:0045453 38 0.903
regulation of vitamin d biosynthetic process GO:0060556 1 0.898
small gtpase mediated signal transduction GO:0007264 97 0.898
Mouse
protein localization to nucleus GO:0034504 121 0.895
Human
negative regulation of interferon gamma mediated signaling pathway GO:0060336 1 0.894
activation of mapk activity GO:0000187 59 0.893
hair follicle development GO:0001942 85 0.892
regulation of apoptotic signaling pathway GO:2001233 197 0.890
Mouse
metanephric glomerular mesangium development GO:0072223 3 0.887
regulation of cell substrate adhesion GO:0010810 73 0.883
notochord development GO:0030903 20 0.882
Mouse
aorta development GO:0035904 23 0.879
Mouse
epidermis development GO:0008544 187 0.878
regulation of cellular ketone metabolic process GO:0010565 66 0.870
response to bmp GO:0071772 14 0.860
Mouse
positive regulation of glial cell proliferation GO:0060252 4 0.859
regulation of chondrocyte differentiation GO:0032330 33 0.856
limb morphogenesis GO:0035108 149 0.855
Mouse
limb development GO:0060173 166 0.847
Mouse
regulation of cell division GO:0051302 76 0.839
sensory organ morphogenesis GO:0090596 242 0.839
Mouse
biomineral tissue development GO:0031214 64 0.829
Human
erk1 and erk2 cascade GO:0070371 77 0.825
regulation of cell adhesion GO:0030155 154 0.825
positive regulation of mitosis GO:0045840 14 0.823
appendage morphogenesis GO:0035107 149 0.820
Zebrafish Mouse
negative regulation of cell proliferation GO:0008285 296 0.816
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.811
Human
positive regulation of cell migration GO:0030335 109 0.810
Human
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.809
aorta smooth muscle tissue morphogenesis GO:0060414 2 0.803
Mouse
antibacterial peptide secretion GO:0002779 1 0.803
prostate epithelial cord elongation GO:0060523 3 0.788
regionalization GO:0003002 337 0.786
regulation of mesenchymal cell proliferation GO:0010464 37 0.785
cardiac ventricle morphogenesis GO:0003208 50 0.782
Mouse
jak stat cascade GO:0007259 42 0.780
nuclear division GO:0000280 158 0.777
peptidyl amino acid modification GO:0018193 336 0.774
negative regulation of cell substrate adhesion GO:0010812 16 0.772
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.766
tissue homeostasis GO:0001894 115 0.765
Mouse
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.764
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.764
Mouse
muscle tissue morphogenesis GO:0060415 53 0.758
Mouse
epidermis morphogenesis GO:0048730 33 0.753
cell migration involved in coronary angiogenesis GO:0060981 1 0.753
negative regulation of immature t cell proliferation GO:0033087 3 0.749
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.748
response to acid chemical GO:0001101 111 0.746
cardiac muscle tissue development GO:0048738 130 0.743
Mouse
positive regulation of odontogenesis GO:0042482 4 0.741
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.741
direct ossification GO:0036072 5 0.739
reactive oxygen species metabolic process GO:0072593 84 0.735
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.731
Rat
negative regulation of release of cytochrome c from mitochondria GO:0090201 6 0.730
cardiocyte differentiation GO:0035051 87 0.726
ear development GO:0043583 200 0.725
Mouse
regulation of cell cycle process GO:0010564 160 0.719
cellular response to abiotic stimulus GO:0071214 56 0.715
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.713
angiogenesis GO:0001525 201 0.711
fibril organization GO:0097435 2 0.711
cellular response to x ray GO:0071481 2 0.709
lung alveolus development GO:0048286 45 0.705
axon guidance GO:0007411 141 0.700
regulation of protein targeting GO:1903533 61 0.698
protein trimerization GO:0070206 13 0.696
negative regulation of neuron migration GO:2001223 6 0.695
Mouse
digestive tract morphogenesis GO:0048546 147 0.691
epithelial cell proliferation GO:0050673 174 0.689
intestinal epithelial structure maintenance GO:0060729 4 0.688
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.680
positive regulation of growth GO:0045927 104 0.673
regulation of reactive oxygen species metabolic process GO:2000377 40 0.673
cellular amide metabolic process GO:0043603 58 0.671
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.664
stem cell development GO:0048864 219 0.661
Human
branching morphogenesis of an epithelial tube GO:0048754 159 0.651
tyrosine phosphorylation of stat protein GO:0007260 23 0.647
striated muscle cell development GO:0055002 125 0.643
development of primary sexual characteristics GO:0045137 143 0.643
response to hyperoxia GO:0055093 2 0.641
Rat
cellular protein catabolic process GO:0044257 155 0.640
regulation of neuron migration GO:2001222 22 0.639
Mouse
regulation of cell cycle GO:0051726 281 0.639
response to low density lipoprotein particle GO:0055098 2 0.630
signal transduction involved in mitotic cell cycle checkpoint GO:0072413 3 0.624
endoderm development GO:0007492 45 0.622
prostate gland epithelium morphogenesis GO:0060740 31 0.617
anatomical structure homeostasis GO:0060249 145 0.616
Mouse
epithelial to mesenchymal transition GO:0001837 47 0.616
Human
positive regulation of cell proliferation involved in heart valve morphogenesis GO:0003251 1 0.612
negative regulation of anoikis GO:2000811 2 0.612
positive regulation of cell development GO:0010720 237 0.611
Human
positive regulation of apoptotic signaling pathway GO:2001235 95 0.611
gland development GO:0048732 330 0.606
regulation of cellular response to growth factor stimulus GO:0090287 82 0.605
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.603
skeletal muscle organ development GO:0060538 163 0.601
muscle tissue development GO:0060537 308 0.590
Mouse
smooth muscle cell migration GO:0014909 10 0.587
regulation of jak stat cascade GO:0046425 34 0.583
positive regulation of leukocyte proliferation GO:0070665 73 0.583
positive regulation of cell cycle GO:0045787 92 0.582
negative regulation of cell adhesion GO:0007162 45 0.579
cell matrix adhesion GO:0007160 68 0.576
Mouse
trabecula formation GO:0060343 24 0.575
regulation of histone acetylation GO:0035065 19 0.572
negative regulation of smooth muscle cell apoptotic process GO:0034392 1 0.572
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.565
multicellular organismal macromolecule metabolic process GO:0044259 19 0.558
Human
response to corticosteroid GO:0031960 20 0.557
Rat
positive regulation of cell aging GO:0090343 1 0.555
cellular response to mechanical stimulus GO:0071260 7 0.553
cerebral cortex development GO:0021987 86 0.551
Mouse
bone trabecula morphogenesis GO:0061430 12 0.547
regulation of mitosis GO:0007088 29 0.546
erythropoietin mediated signaling pathway GO:0038162 1 0.543
cellular response to inorganic substance GO:0071241 37 0.539
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.533
regulation of mapk cascade GO:0043408 248 0.532
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.525
negative regulation of phosphatidylinositol 3 kinase activity GO:0043553 1 0.524
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.524
positive regulation of neuron projection regeneration GO:0070572 2 0.521
chondrocyte development GO:0002063 24 0.516
Mouse
positive regulation of tyrosine phosphorylation of stat1 protein GO:0042511 1 0.516
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.514
frontal suture morphogenesis GO:0060364 2 0.511
negative regulation of angiogenesis GO:0016525 25 0.511
odontogenesis of dentin containing tooth GO:0042475 66 0.508
mitotic g1 dna damage checkpoint GO:0031571 4 0.505
cellular response to thyroid hormone stimulus GO:0097067 1 0.501
cellular response to estradiol stimulus GO:0071392 6 0.500
positive regulation of nervous system development GO:0051962 221 0.499
glycoprotein metabolic process GO:0009100 116 0.499
Mouse
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.494
negative regulation of vasoconstriction GO:0045906 2 0.490
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.489
regulation of odontogenesis GO:0042481 18 0.485
response to thyroid hormone GO:0097066 2 0.484
cellular ketone metabolic process GO:0042180 84 0.482
negative regulation of growth GO:0045926 99 0.478
amine metabolic process GO:0009308 45 0.478
regulation of tissue remodeling GO:0034103 38 0.476
response to transforming growth factor beta GO:0071559 88 0.470
Rat
regulation of rho protein signal transduction GO:0035023 71 0.468
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.467
Human
protein targeting GO:0006605 143 0.463
cellular response to vitamin GO:0071295 2 0.463
Rat
positive regulation of ossification GO:0045778 47 0.462
regulation of protein import into nucleus translocation GO:0033158 2 0.462
oocyte axis specification GO:0007309 2 0.460
regulation of cellular amino acid metabolic process GO:0006521 5 0.459
blood vessel morphogenesis GO:0048514 285 0.456
Mouse
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.455
regulation of serotonin uptake GO:0051611 2 0.450
cardiac endothelial cell differentiation GO:0003348 4 0.445
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.439
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 3 0.436
prostate glandular acinus morphogenesis GO:0060526 7 0.435
positive regulation of bone remodeling GO:0046852 13 0.432
response to retinoic acid GO:0032526 56 0.425
Rat
response to vitamin a GO:0033189 1 0.417
fat cell differentiation GO:0045444 160 0.416
muscle cell development GO:0055001 133 0.416
epithelial cell proliferation involved in prostate gland development GO:0060767 11 0.415
tissue remodeling GO:0048771 102 0.415
maternal placenta development GO:0001893 20 0.412
apoptotic process involved in mammary gland involution GO:0060057 4 0.412
trophectodermal cellular morphogenesis GO:0001831 3 0.410
cytokine mediated signaling pathway GO:0019221 115 0.409
positive regulation of mitotic cell cycle GO:0045931 41 0.409
cell migration involved in vasculogenesis GO:0035441 2 0.406
forebrain development GO:0030900 302 0.405
Mouse
positive regulation of stem cell differentiation GO:2000738 23 0.405
Human
mitotic nuclear division GO:0007067 48 0.402
regulation of cartilage development GO:0061035 44 0.401
regulation of kinase activity GO:0043549 249 0.400
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 15 0.399
membrane organization GO:0061024 245 0.397
digestive system development GO:0055123 200 0.397
Mouse
osteoblast development GO:0002076 17 0.396
protein oligomerization GO:0051259 67 0.394
stem cell differentiation GO:0048863 268 0.391
Human
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.391
response to increased oxygen levels GO:0036296 2 0.384
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.384
positive regulation of smooth muscle cell migration GO:0014911 4 0.383
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.378
Mouse
alpha amino acid metabolic process GO:1901605 59 0.378
positive regulation of mapk cascade GO:0043410 170 0.376
regulation of odontogenesis of dentin containing tooth GO:0042487 11 0.374
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis GO:0060527 7 0.370
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.367
Mouse
regulation of lipid kinase activity GO:0043550 14 0.364
metanephric mesenchymal cell migration GO:0035789 2 0.363
positive regulation of axon extension GO:0045773 20 0.362
nuclear import GO:0051170 95 0.356
aminoglycan metabolic process GO:0006022 34 0.356
acylglycerol metabolic process GO:0006639 55 0.356
regulation of protein serine threonine kinase activity GO:0071900 157 0.348
positive regulation of skeletal muscle cell proliferation GO:0014858 2 0.346
response to monosaccharide GO:0034284 67 0.345
detection of molecule of bacterial origin GO:0032490 2 0.342
muscle cell proliferation GO:0033002 52 0.341
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.340
Mouse
extracellular fibril organization GO:0043206 2 0.340
protein localization to organelle GO:0033365 185 0.337
Human
fused antrum stage GO:0048165 1 0.336
positive regulation of programmed cell death GO:0043068 218 0.335
regulation of macrophage chemotaxis GO:0010758 8 0.334
embryonic placenta development GO:0001892 98 0.334
multicellular organismal catabolic process GO:0044243 7 0.334
developmental maturation GO:0021700 193 0.331
negative regulation of blood vessel morphogenesis GO:2000181 25 0.330
response to extracellular stimulus GO:0009991 127 0.330
Rat
regulation of leukocyte differentiation GO:1902105 159 0.329
response to oxygen levels GO:0070482 62 0.328
Rat
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.327
cardiac chamber development GO:0003205 108 0.326
Mouse
chronic inflammatory response GO:0002544 9 0.324
regulation of endodermal cell differentiation GO:1903224 2 0.323
liver development GO:0001889 66 0.321
inner cell mass cellular morphogenesis GO:0001828 1 0.321
reactive nitrogen species metabolic process GO:2001057 0 0.318
endoderm formation GO:0001706 20 0.316
eye photoreceptor cell differentiation GO:0001754 41 0.314
kit signaling pathway GO:0038109 3 0.312
prostate gland development GO:0030850 48 0.311
regulation of tooth mineralization GO:0070170 2 0.310
negative regulation of endodermal cell differentiation GO:1903225 1 0.309
response to nicotine GO:0035094 6 0.306
phospholipid metabolic process GO:0006644 87 0.306
positive regulation of histone modification GO:0031058 28 0.304
intracellular signal transduction involved in g1 dna damage checkpoint GO:1902400 3 0.303
collagen catabolic process GO:0030574 6 0.302
positive regulation of map kinase activity GO:0043406 84 0.302
oocyte construction GO:0007308 2 0.302
response to estrogen GO:0043627 24 0.298
Rat
positive regulation of smad protein import into nucleus GO:0060391 2 0.298
organ growth GO:0035265 117 0.295
female gamete generation GO:0007292 74 0.295
macromolecule catabolic process GO:0009057 281 0.292
positive regulation of peptidyl lysine acetylation GO:2000758 9 0.291
regulation of receptor activity GO:0010469 41 0.291
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.289
cellular response to peptide GO:1901653 92 0.288
cellular response to erythropoietin GO:0036018 1 0.286
negative regulation of reactive oxygen species metabolic process GO:2000378 10 0.285
ventricular cardiac muscle tissue development GO:0003229 38 0.285
Mouse
negative regulation of fibroblast proliferation GO:0048147 14 0.284
regulation of hair follicle cell proliferation GO:0071336 2 0.283
nuclear transport GO:0051169 139 0.278
regulation of nucleocytoplasmic transport GO:0046822 73 0.276
positive regulation of protein acetylation GO:1901985 9 0.276
cardiac cell development GO:0055006 41 0.274
superoxide metabolic process GO:0006801 27 0.272
negative regulation of dna replication GO:0008156 4 0.269
monocyte differentiation GO:0030224 9 0.268
dna replication GO:0006260 52 0.266
response to estradiol GO:0032355 12 0.265
Rat
response to growth factor GO:0070848 198 0.265
Mouse Rat
oxidation reduction process GO:0055114 342 0.264
tendon development GO:0035989 6 0.264
Mouse
positive regulation of activated t cell proliferation GO:0042104 8 0.263
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 1 0.262
regulation of tyrosine phosphorylation of stat1 protein GO:0042510 2 0.260
g protein coupled receptor signaling pathway involved in heart process GO:0086103 4 0.260
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.260
positive regulation of cartilage development GO:0061036 18 0.259
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.258
angiogenesis involved in coronary vascular morphogenesis GO:0060978 2 0.257
response to erythropoietin GO:0036017 1 0.256
common partner smad protein phosphorylation GO:0007182 2 0.255
sensory perception of mechanical stimulus GO:0050954 107 0.252
Human Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.251
regulation of dna replication GO:0006275 17 0.248
regulation of lens epithelial cell proliferation GO:2001109 1 0.247
pancreas development GO:0031016 57 0.247
response to decreased oxygen levels GO:0036293 59 0.246
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.245
cardiac muscle cell differentiation GO:0055007 69 0.245
regulation of vasculogenesis GO:2001212 9 0.243
muscle system process GO:0003012 141 0.242
cell division GO:0051301 120 0.241
heart valve development GO:0003170 23 0.240
regulation of glutamine family amino acid metabolic process GO:0000820 1 0.238
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 2 0.238
reactive oxygen species biosynthetic process GO:1903409 8 0.238
ovarian follicle development GO:0001541 40 0.237
regulation of endothelial cell proliferation GO:0001936 23 0.236
dna metabolic process GO:0006259 303 0.236
establishment of protein localization to organelle GO:0072594 118 0.236
protein import into nucleus GO:0006606 95 0.236
sequestering of bmp in extracellular matrix GO:0035582 3 0.235
organelle fission GO:0048285 170 0.231
cell proliferation in hindbrain GO:0021534 10 0.228
ras protein signal transduction GO:0007265 77 0.226
Mouse
nitrogen compound transport GO:0071705 271 0.226
cloacal septation GO:0060197 2 0.224
positive regulation of nitric oxide synthase activity GO:0051000 2 0.224
neuron projection guidance GO:0097485 141 0.222
negative regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000160 1 0.221
response to fibroblast growth factor GO:0071774 47 0.221
Rat
positive regulation of dephosphorylation GO:0035306 6 0.220
otic vesicle development GO:0071599 14 0.219
Mouse
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.217
myeloid progenitor cell differentiation GO:0002318 8 0.211
respiratory system development GO:0060541 190 0.211
response to vitamin GO:0033273 6 0.210
Rat
phosphatidylinositol metabolic process GO:0046488 45 0.210
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.209
somatic stem cell maintenance GO:0035019 47 0.208
protein kinase b signaling GO:0043491 74 0.208
regulation of fat cell differentiation GO:0045598 81 0.207
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.206
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.205
multi multicellular organism process GO:0044706 109 0.204
neutral lipid metabolic process GO:0006638 57 0.204
negative regulation of embryonic development GO:0045992 22 0.203
sulfur compound metabolic process GO:0006790 100 0.203
skin morphogenesis GO:0043589 38 0.202
Human
regulation of androgen receptor signaling pathway GO:0060765 3 0.201
exocrine system development GO:0035272 45 0.201
positive regulation of t cell proliferation GO:0042102 52 0.198
modulation by virus of host morphology or physiology GO:0019048 3 0.196
stem cell maintenance GO:0019827 130 0.195
macrophage colony stimulating factor signaling pathway GO:0038145 2 0.194
regulation of growth of symbiont in host GO:0044126 19 0.194
organic hydroxy compound catabolic process GO:1901616 25 0.192
epithelial tube morphogenesis GO:0060562 303 0.189
positive regulation of cell substrate adhesion GO:0010811 47 0.189
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.188
regulation of osteoclast differentiation GO:0045670 36 0.188
axonogenesis GO:0007409 274 0.187
signal transduction involved in mitotic g1 dna damage checkpoint GO:0072431 3 0.186
positive regulation of cardioblast differentiation GO:0051891 3 0.183
positive regulation of leukocyte differentiation GO:1902107 86 0.181
negative regulation of mapk cascade GO:0043409 65 0.181
myofibril assembly GO:0030239 34 0.181
posttranscriptional regulation of gene expression GO:0010608 155 0.180
gastrulation GO:0007369 116 0.180
regulation of hormone levels GO:0010817 211 0.177
pro b cell differentiation GO:0002328 10 0.176
sensory perception GO:0007600 245 0.174
Human Mouse
protein autoprocessing GO:0016540 2 0.173
positive regulation of epithelial to mesenchymal transition GO:0010718 13 0.172
Human
tooth mineralization GO:0034505 9 0.172
Human
t cell receptor v d j recombination GO:0033153 5 0.170
positive regulation of rho protein signal transduction GO:0035025 7 0.169
Mouse
cell growth involved in cardiac muscle cell development GO:0061049 3 0.168
regulation of erk1 and erk2 cascade GO:0070372 71 0.168
fatty acid metabolic process GO:0006631 121 0.167
digestion GO:0007586 40 0.166
negative regulation of molecular function GO:0044092 258 0.165
bmp signaling pathway GO:0030509 93 0.165
positive regulation of histone acetylation GO:0035066 8 0.165
positive regulation of cellular amine metabolic process GO:0033240 5 0.164
myeloid leukocyte migration GO:0097529 57 0.164
positive regulation of interleukin 17 production GO:0032740 3 0.164
pallium development GO:0021543 120 0.163
Mouse
response to glucocorticoid GO:0051384 20 0.162
endothelial cell proliferation GO:0001935 27 0.161
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.161
establishment or maintenance of cell polarity GO:0007163 86 0.161
coronary vasculature development GO:0060976 12 0.160
regulation of protein kinase b signaling GO:0051896 56 0.160
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 2 0.160
response to inorganic substance GO:0010035 96 0.158
Rat
regulation of bone resorption GO:0045124 24 0.158
negative regulation of fat cell differentiation GO:0045599 36 0.157
retinal blood vessel morphogenesis GO:0061304 3 0.157
regulation of nuclear division GO:0051783 56 0.157
cellular component assembly involved in morphogenesis GO:0010927 139 0.157
regulation of stress activated mapk cascade GO:0032872 69 0.157
negative regulation of macrophage cytokine production GO:0010936 1 0.157
negative regulation of gastrulation GO:2000542 3 0.156
mammary gland branching involved in pregnancy GO:0060745 6 0.155
regulation of epithelial cell proliferation involved in prostate gland development GO:0060768 10 0.154
genitalia development GO:0048806 37 0.153
positive regulation of dna replication GO:0045740 9 0.153
anatomical structure maturation GO:0071695 49 0.152
integrin mediated signaling pathway GO:0007229 27 0.152
regulation of muscle cell apoptotic process GO:0010660 17 0.152
hindbrain radial glia guided cell migration GO:0021932 12 0.151
positive regulation of chromosome organization GO:2001252 33 0.150
positive regulation of chromatin modification GO:1903310 28 0.149
positive regulation of smooth muscle cell differentiation GO:0051152 2 0.148
positive regulation of stem cell proliferation GO:2000648 59 0.148
mapk cascade GO:0000165 281 0.148
regulation of neuron projection regeneration GO:0070570 7 0.147
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.147
multicellular organismal metabolic process GO:0044236 28 0.147
Human
tyrosine phosphorylation of stat3 protein GO:0042503 12 0.145

Col1a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 1.000
Human
musculoskeletal system disease DOID:17 0 1.000
Human
connective tissue disease DOID:65 0 1.000
Human
bone remodeling disease DOID:0080005 0 0.988
Human
bone disease DOID:0080001 0 0.988
Human
myopathy DOID:423 0 0.970
congenital muscular dystrophy DOID:0050557 0 0.970
muscular disease DOID:0080000 0 0.970
muscular dystrophy DOID:9884 0 0.970
muscle tissue disease DOID:66 0 0.970
osteoporosis DOID:11476 0 0.897
Human
bone resorption disease DOID:0080011 0 0.897
Human
collagen disease DOID:854 0 0.825
Human
bone development disease DOID:0080006 0 0.822
Human
disease of cellular proliferation DOID:14566 0 0.352
cancer DOID:162 0 0.334
organ system cancer DOID:0050686 0 0.334
ehlers danlos syndrome DOID:13359 0 0.250
Human
osteochondrodysplasia DOID:2256 0 0.215
Human
osteogenesis imperfecta DOID:12347 0 0.176
Human