IMP
Process View
negative regulation of endothelial cell proliferation
Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of endothelial cell proliferation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Tgfbr2 | transforming growth factor, beta receptor II | 0.998 | Mouse | |
| Col1a1 | collagen, type I, alpha 1 | 0.983 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.824 | ||
| Apc | adenomatosis polyposis coli | 0.804 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.753 | ||
| Vegfa | vascular endothelial growth factor A | 0.743 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.646 | ||
| Acvr1 | activin A receptor, type 1 | 0.590 | Mouse | |
| Lepr | leptin receptor | 0.426 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.419 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.408 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.369 | ||
| Esr1 | estrogen receptor 1 (alpha) | 0.349 | ||
| Pten | phosphatase and tensin homolog | 0.329 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.308 | ||
| Tgfbr1 | transforming growth factor, beta receptor I | 0.305 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.288 | ||
| Cav1 | caveolin 1, caveolae protein | 0.287 | ||
| Ghr | growth hormone receptor | 0.279 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.271 | ||
| Foxc1 | forkhead box C1 | 0.248 | ||
| Acvrl1 | activin A receptor, type II-like 1 | 0.235 | ||
| Egfr | epidermal growth factor receptor | 0.174 | ||
| Atp5b | ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit | 0.158 | ||
| Prrx1 | paired related homeobox 1 | 0.144 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.118 | Mouse | |
| Sox9 | SRY-box containing gene 9 | 0.115 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.105 | ||
| Ece1 | endothelin converting enzyme 1 | 0.104 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.103 | ||
| Cdh5 | cadherin 5 | 0.102 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.091 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.088 | ||
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.088 | ||
| Shh | sonic hedgehog | 0.084 | ||
| Ptrf | polymerase I and transcript release factor | 0.074 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.073 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.072 | ||
| Jag1 | jagged 1 | 0.071 | ||
| Braf | Braf transforming gene | 0.069 | ||
| Dmd | dystrophin, muscular dystrophy | 0.067 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.067 | ||
| Eng | endoglin | 0.065 | Human | |
| Rxra | retinoid X receptor alpha | 0.063 | ||
| Amhr2 | anti-Mullerian hormone type 2 receptor | 0.060 | Mouse | |
| Rara | retinoic acid receptor, alpha | 0.055 | ||
| Ednra | endothelin receptor type A | 0.054 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.052 | ||
| Nos1 | nitric oxide synthase 1, neuronal | 0.048 | ||
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.048 | ||
| Lox | lysyl oxidase | 0.045 | ||
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.043 | ||
| Smo | smoothened homolog (Drosophila) | 0.041 | ||
| Tbx1 | T-box 1 | 0.039 | ||
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.038 | ||
| Lyz2 | lysozyme 2 | 0.037 | ||
| Ptch1 | patched homolog 1 | 0.037 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.037 | ||
| Apoc4 | apolipoprotein C-IV | 0.036 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.036 | ||
| Mgp | matrix Gla protein | 0.034 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.034 | ||
| Foxc2 | forkhead box C2 | 0.033 | ||
| Kiss1 | KiSS-1 metastasis-suppressor | 0.032 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.031 | ||
| Fermt2 | fermitin family homolog 2 (Drosophila) | 0.031 | ||
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.030 | ||
| Fbn1 | fibrillin 1 | 0.030 | ||
| Trp53 | transformation related protein 53 | 0.030 | ||
| Bmp2 | bone morphogenetic protein 2 | 0.028 | ||
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.028 | ||
| Prrx2 | paired related homeobox 2 | 0.027 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.027 | ||
| Sgca | sarcoglycan, alpha (dystrophin-associated glycoprotein) | 0.027 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.026 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.025 | ||
| Prkg1 | protein kinase, cGMP-dependent, type I | 0.024 | ||
| Tgfbr3 | transforming growth factor, beta receptor III | 0.024 | ||
| Kitl | kit ligand | 0.024 | ||
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.023 | ||
| Serpina3m | serine (or cysteine) peptidase inhibitor, clade A, member 3M | 0.023 | Rat | |
| Rarg | retinoic acid receptor, gamma | 0.023 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.022 | ||
| Nr2f1 | nuclear receptor subfamily 2, group F, member 1 | 0.022 | ||
| Tlr4 | toll-like receptor 4 | 0.022 | ||
| Esr2 | estrogen receptor 2 (beta) | 0.021 | ||
| Ret | ret proto-oncogene | 0.021 | ||
| Lep | leptin | 0.020 | ||
| Ar | androgen receptor | 0.020 | ||
| Lama2 | laminin, alpha 2 | 0.020 | ||
| Rarb | retinoic acid receptor, beta | 0.019 | ||
| Col4a1 | collagen, type IV, alpha 1 | 0.019 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.018 | ||
| Atp7a | ATPase, Cu++ transporting, alpha polypeptide | 0.018 | ||
| Fgf8 | fibroblast growth factor 8 | 0.017 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.017 | ||
| Timp3 | tissue inhibitor of metalloproteinase 3 | 0.017 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.017 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.016 | ||
| Ldlr | low density lipoprotein receptor | 0.016 | ||
| Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 0.015 | ||
| Serpina3k | serine (or cysteine) peptidase inhibitor, clade A, member 3K | 0.015 | Rat | |
| Il6st | interleukin 6 signal transducer | 0.015 | ||
| Rb1 | retinoblastoma 1 | 0.015 | ||
| Lmna | lamin A | 0.015 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.015 | ||
| Agtr2 | angiotensin II receptor, type 2 | 0.015 | ||
| Cyp19a1 | cytochrome P450, family 19, subfamily a, polypeptide 1 | 0.015 | ||
| Bmp5 | bone morphogenetic protein 5 | 0.015 | ||
| Fkbp9 | FK506 binding protein 9 | 0.015 | ||
| Adipoq | adiponectin, C1Q and collagen domain containing | 0.015 | ||
| Pmp22 | peripheral myelin protein 22 | 0.014 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.014 | ||
| Stk3 | serine/threonine kinase 3 (Ste20, yeast homolog) | 0.014 | ||
| Postn | periostin, osteoblast specific factor | 0.014 | ||
| Fstl1 | follistatin-like 1 | 0.014 | ||
| Ptk2 | PTK2 protein tyrosine kinase 2 | 0.014 | ||
| Foxg1 | forkhead box G1 | 0.014 | ||
| Sema3c | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.014 | ||
| Eln | elastin | 0.014 | ||
| Gfpt2 | glutamine fructose-6-phosphate transaminase 2 | 0.014 | ||
| Lama4 | laminin, alpha 4 | 0.013 | ||
| Bmper | BMP-binding endothelial regulator | 0.013 | ||
| Pcolce | procollagen C-endopeptidase enhancer protein | 0.013 | ||
| Emcn | endomucin | 0.013 | ||
| Efnb2 | ephrin B2 | 0.013 | ||
| Prlr | prolactin receptor | 0.013 | ||
| Efemp2 | epidermal growth factor-containing fibulin-like extracellular matrix protein 2 | 0.013 | ||
| Col5a2 | collagen, type V, alpha 2 | 0.013 | ||
| Fgf7 | fibroblast growth factor 7 | 0.012 | ||
| Abcc9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | 0.012 | ||
| Jam2 | junction adhesion molecule 2 | 0.012 | ||
| Trove2 | TROVE domain family, member 2 | 0.012 | ||
| Nf2 | neurofibromatosis 2 | 0.012 | ||
| Mfng | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.012 | ||
| 1500015O10Rik | RIKEN cDNA 1500015O10 gene | 0.011 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.011 | ||
| Serpinh1 | serine (or cysteine) peptidase inhibitor, clade H, member 1 | 0.011 | ||
| Vcl | vinculin | 0.011 | ||
| Col4a2 | collagen, type IV, alpha 2 | 0.011 | ||
| Myh2 | myosin, heavy polypeptide 2, skeletal muscle, adult | 0.011 | ||
| Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.011 | ||
| Rhoj | ras homolog gene family, member J | 0.011 | ||
| Fzd1 | frizzled homolog 1 (Drosophila) | 0.010 | ||
| Cd44 | CD44 antigen | 0.010 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.010 |