IMP

Process View

Mus musculus

10 genes annotated in mouse

regulation of epithelial cell proliferation involved in prostate gland development

Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of epithelial cell proliferation involved in prostate gland development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of epithelial cell proliferation involved in prostate gland development" (in gray)

Name	Description	Probability	Func Analog Organism
Ctnnb1	catenin (cadherin associated protein), beta 1	0.999
Fgfr2	fibroblast growth factor receptor 2	0.986
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.941
Pten	phosphatase and tensin homolog	0.890
Notch1	Notch gene homolog 1 (Drosophila)	0.807
Trp53	transformation related protein 53	0.776
Sox9	SRY-box containing gene 9	0.737
Psen1	presenilin 1	0.712
Shh	sonic hedgehog	0.644
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.619
Fgfr1	fibroblast growth factor receptor 1	0.568
Rxra	retinoid X receptor alpha	0.539
Msx1	homeobox, msh-like 1	0.531
Gli3	GLI-Kruppel family member GLI3	0.472
Ar	androgen receptor	0.455
Rb1	retinoblastoma 1	0.412
Foxc1	forkhead box C1	0.349
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.331
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.277
Bmp4	bone morphogenetic protein 4	0.275
Esr1	estrogen receptor 1 (alpha)	0.269
Notch2	Notch gene homolog 2 (Drosophila)	0.241	Mouse
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.231
Dll1	delta-like 1 (Drosophila)	0.197
Jag1	jagged 1	0.177
Pax3	paired box gene 3	0.168
Trp63	transformation related protein 63	0.163
Gata4	GATA binding protein 4	0.158
Col1a1	collagen, type I, alpha 1	0.154
Smad3	MAD homolog 3 (Drosophila)	0.142
Pitx2	paired-like homeodomain transcription factor 2	0.132
Apc	adenomatosis polyposis coli	0.130
Nos3	nitric oxide synthase 3, endothelial cell	0.123
Nf1	neurofibromatosis 1	0.116
Dlx2	distal-less homeobox 2	0.113
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.112
Vhl	von Hippel-Lindau tumor suppressor	0.108
Chd7	chromodomain helicase DNA binding protein 7	0.108
Braf	Braf transforming gene	0.094
Lepr	leptin receptor	0.090
Hes1	hairy and enhancer of split 1 (Drosophila)	0.087
Hand2	heart and neural crest derivatives expressed transcript 2	0.084
Stat3	signal transducer and activator of transcription 3	0.079
Fgfr3	fibroblast growth factor receptor 3	0.074
Vegfa	vascular endothelial growth factor A	0.072
Efnb2	ephrin B2	0.071
Ptch1	patched homolog 1	0.071
Foxa2	forkhead box A2	0.064
Smo	smoothened homolog (Drosophila)	0.061
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.060
Gli2	GLI-Kruppel family member GLI2	0.058
Esr2	estrogen receptor 2 (beta)	0.057
Pgr	progesterone receptor	0.055
Hif1a	hypoxia inducible factor 1, alpha subunit	0.052
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.051	Mouse
Smad4	MAD homolog 4 (Drosophila)	0.050
Ahr	aryl-hydrocarbon receptor	0.050
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.049
Egfr	epidermal growth factor receptor	0.045
Col2a1	collagen, type II, alpha 1	0.045
Pax8	paired box gene 8	0.044
Meox2	mesenchyme homeobox 2	0.042
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.042
Fgf10	fibroblast growth factor 10	0.041
Ccnd1	cyclin D1	0.041
Amhr2	anti-Mullerian hormone type 2 receptor	0.039
Dlx5	distal-less homeobox 5	0.039
Kit	kit oncogene	0.039
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.035
Apoe	apolipoprotein E	0.035
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.034
Pax2	paired box gene 2	0.031
Nog	noggin	0.031
Foxc2	forkhead box C2	0.031
Eya1	eyes absent 1 homolog (Drosophila)	0.031
Drd2	dopamine receptor D2	0.029
Otx2	orthodenticle homolog 2 (Drosophila)	0.029
Pbx1	pre B-cell leukemia transcription factor 1	0.029
Vangl2	vang-like 2 (van gogh, Drosophila)	0.029
Tbx1	T-box 1	0.029
Psen2	presenilin 2	0.028
Msh2	mutS homolog 2 (E. coli)	0.028
Hoxa10	homeobox A10	0.028
Zeb1	zinc finger E-box binding homeobox 1	0.027
Hoxa2	homeobox A2	0.025
Fgf8	fibroblast growth factor 8	0.025
Ptgs2	prostaglandin-endoperoxide synthase 2	0.024
Isl1	ISL1 transcription factor, LIM/homeodomain	0.024
Hoxa13	homeobox A13	0.023
Prlr	prolactin receptor	0.023
Gata3	GATA binding protein 3	0.021
Tgfb2	transforming growth factor, beta 2	0.020
Bcl2	B-cell leukemia/lymphoma 2	0.020
Hoxd13	homeobox D13	0.019
Gsk3b	glycogen synthase kinase 3 beta	0.019
Vdr	vitamin D receptor	0.018
Bmp7	bone morphogenetic protein 7	0.017
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.017
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.017
Rarb	retinoic acid receptor, beta	0.017
Egfl7	EGF-like domain 7	0.017
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.016
Lrp6	low density lipoprotein receptor-related protein 6	0.016
Mdm2	transformed mouse 3T3 cell double minute 2	0.016
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.016
Hr	hairless	0.016
Thbs1	thrombospondin 1	0.015
Wnt3a	wingless-related MMTV integration site 3A	0.015
Pparg	peroxisome proliferator activated receptor gamma	0.015
Kl	klotho	0.015
Emx2	empty spiracles homolog 2 (Drosophila)	0.015
Fgf9	fibroblast growth factor 9	0.015
Satb2	special AT-rich sequence binding protein 2	0.014
Sox2	SRY-box containing gene 2	0.014
Lep	leptin	0.014
Tbx3	T-box 3	0.014
Fshr	follicle stimulating hormone receptor	0.014
Rarg	retinoic acid receptor, gamma	0.014
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.013
Thrb	thyroid hormone receptor beta	0.013
Efna2	ephrin A2	0.013
Tcfap2a	transcription factor AP-2, alpha	0.012
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.012
Smad2	MAD homolog 2 (Drosophila)	0.012
Tenc1	tensin like C1 domain-containing phosphatase	0.012
Psap	prosaposin	0.012
Itga3	integrin alpha 3	0.012
Hand1	heart and neural crest derivatives expressed transcript 1	0.011
Pla2g2c	phospholipase A2, group IIC	0.011
Npc1	Niemann Pick type C1	0.011
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.011
Ghr	growth hormone receptor	0.011
Il6st	interleukin 6 signal transducer	0.011
Npr2	natriuretic peptide receptor 2	0.011
Foxg1	forkhead box G1	0.011
Alx4	aristaless-like homeobox 4	0.011
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.011
Gsc	goosecoid homeobox	0.010
Nf2	neurofibromatosis 2	0.010
Pthlh	parathyroid hormone-like peptide	0.010