IMP

Process View

Mus musculus

2 genes annotated in mouse

cloacal septation

The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cloacal septation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cloacal septation" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	0.999
Fgfr2	fibroblast growth factor receptor 2	0.999
Sox9	SRY-box containing gene 9	0.981
Gli3	GLI-Kruppel family member GLI3	0.968
Foxc1	forkhead box C1	0.897
Ctnnb1	catenin (cadherin associated protein), beta 1	0.890
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.884
Pten	phosphatase and tensin homolog	0.879
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.773
Pax3	paired box gene 3	0.752
Tgfb2	transforming growth factor, beta 2	0.682
Prrx1	paired related homeobox 1	0.680
Apc	adenomatosis polyposis coli	0.651
Trp63	transformation related protein 63	0.648
Bmp7	bone morphogenetic protein 7	0.558
Smo	smoothened homolog (Drosophila)	0.522
Dlx5	distal-less homeobox 5	0.502
Fgfr1	fibroblast growth factor receptor 1	0.502
Msx1	homeobox, msh-like 1	0.451
Foxc2	forkhead box C2	0.400
Gli2	GLI-Kruppel family member GLI2	0.336
Rara	retinoic acid receptor, alpha	0.317
Fgfr3	fibroblast growth factor receptor 3	0.308
Bmp4	bone morphogenetic protein 4	0.308
Tcfap2a	transcription factor AP-2, alpha	0.305
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.294
Chrd	chordin	0.279
Ptch1	patched homolog 1	0.257
Tbx1	T-box 1	0.253
Nodal	nodal	0.233
Rarb	retinoic acid receptor, beta	0.224
Col1a1	collagen, type I, alpha 1	0.224
Fgf8	fibroblast growth factor 8	0.181
Rxra	retinoid X receptor alpha	0.180
Eya1	eyes absent 1 homolog (Drosophila)	0.132
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.130
Otx2	orthodenticle homolog 2 (Drosophila)	0.126
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.120
Prrx2	paired related homeobox 2	0.117
Hand2	heart and neural crest derivatives expressed transcript 2	0.115
Hand1	heart and neural crest derivatives expressed transcript 1	0.109
Zeb1	zinc finger E-box binding homeobox 1	0.108
Meox2	mesenchyme homeobox 2	0.104
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.098
Pax6	paired box gene 6	0.095
Msx2	homeobox, msh-like 2	0.092
Fgf10	fibroblast growth factor 10	0.092
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.083
Vegfa	vascular endothelial growth factor A	0.081
Wnt3a	wingless-related MMTV integration site 3A	0.058
Mdm2	transformed mouse 3T3 cell double minute 2	0.052
Alx4	aristaless-like homeobox 4	0.050
Pitx2	paired-like homeodomain transcription factor 2	0.048
Tgfbr2	transforming growth factor, beta receptor II	0.048
Nog	noggin	0.046
Trp73	transformation related protein 73	0.045	Mouse
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.042
Rarg	retinoic acid receptor, gamma	0.042
Runx2	runt related transcription factor 2	0.040
Acvr1	activin A receptor, type 1	0.040
Lrp6	low density lipoprotein receptor-related protein 6	0.038
Rb1	retinoblastoma 1	0.038
Ednra	endothelin receptor type A	0.035
Sfn	stratifin	0.034
Psen1	presenilin 1	0.034
Esr1	estrogen receptor 1 (alpha)	0.034
Nf1	neurofibromatosis 1	0.033
Trp53	transformation related protein 53	0.032	Mouse
Gja1	gap junction protein, alpha 1	0.032
Mdm4	transformed mouse 3T3 cell double minute 4	0.031
Alx1	ALX homeobox 1	0.030
Zic3	zinc finger protein of the cerebellum 3	0.028
Tcof1	Treacher Collins Franceschetti syndrome 1, homolog	0.027
Vangl2	vang-like 2 (van gogh, Drosophila)	0.025
Egfr	epidermal growth factor receptor	0.025
Yap1	yes-associated protein 1	0.024
Ece1	endothelin converting enzyme 1	0.024
Gsc	goosecoid homeobox	0.023
Pbx1	pre B-cell leukemia transcription factor 1	0.022
Cdx2	caudal type homeobox 2	0.021
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.019
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.019
Smad3	MAD homolog 3 (Drosophila)	0.019
Bmper	BMP-binding endothelial regulator	0.019
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.019
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.019
Pax9	paired box gene 9	0.018
Lef1	lymphoid enhancer binding factor 1	0.018
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.015
Sox4	SRY-box containing gene 4	0.015
Braf	Braf transforming gene	0.014
Hr	hairless	0.014
Foxh1	forkhead box H1	0.013
Pthlh	parathyroid hormone-like peptide	0.013
Dlx6	distal-less homeobox 6	0.013
Sox2	SRY-box containing gene 2	0.013
Kit	kit oncogene	0.013
Emx2	empty spiracles homolog 2 (Drosophila)	0.012
Emx1	empty spiracles homolog 1 (Drosophila)	0.012
Smn1	survival motor neuron 1	0.011
Kif3a	kinesin family member 3A	0.011
Hhat	hedgehog acyltransferase	0.011
Hoxd13	homeobox D13	0.011
Pax2	paired box gene 2	0.011
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.011
En1	engrailed 1	0.010
Gbx2	gastrulation brain homeobox 2	0.010
Jag1	jagged 1	0.010
Mks1	Meckel syndrome, type 1	0.010
Ccnd1	cyclin D1	0.010