Mus musculus

16 known processes

Lat

linker for activation of T cells

Lat biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
t cell receptor signaling pathway GO:0050852 46 1.000
t cell differentiation in thymus GO:0033077 77 0.999
antigen receptor mediated signaling pathway GO:0050851 64 0.999
leukocyte differentiation GO:0002521 342 0.996
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.996
cd4 positive cd25 positive alpha beta regulatory t cell differentiation GO:0002361 4 0.995
regulation of mast cell activation GO:0033003 21 0.994
positive regulation of regulatory t cell differentiation GO:0045591 4 0.992
immune response activating signal transduction GO:0002757 116 0.989
regulation of cell activation GO:0050865 289 0.982
Human
mast cell activation GO:0045576 27 0.977
hematopoietic stem cell migration GO:0035701 1 0.969
t cell differentiation GO:0030217 174 0.968
positive regulation of gamma delta t cell differentiation GO:0045588 6 0.958
t cell selection GO:0045058 34 0.956
thymic t cell selection GO:0045061 22 0.952
positive regulation of exocytosis GO:0045921 20 0.947
regulation of t cell anergy GO:0002667 4 0.944
lymphocyte differentiation GO:0030098 242 0.939
negative regulation of t cell mediated cytotoxicity GO:0001915 3 0.938
t cell activation GO:0042110 289 0.928
Human
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.907
leukocyte proliferation GO:0070661 172 0.902
regulation of alpha beta t cell differentiation GO:0046637 35 0.898
regulation of lymphocyte activation GO:0051249 240 0.897
Human
mast cell activation involved in immune response GO:0002279 20 0.872
positive t cell selection GO:0043368 23 0.853
regulation of t cell mediated cytotoxicity GO:0001914 18 0.850
regulation of mast cell activation involved in immune response GO:0033006 17 0.839
regulation of regulated secretory pathway GO:1903305 20 0.831
serotonin secretion involved in inflammatory response GO:0002442 4 0.818
negative thymic t cell selection GO:0045060 12 0.815
regulation of cellular ketone metabolic process GO:0010565 66 0.808
regulation of lymphocyte anergy GO:0002911 4 0.789
mast cell mediated immunity GO:0002448 20 0.784
cellular amine metabolic process GO:0044106 44 0.781
lymphocyte mediated immunity GO:0002449 139 0.781
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.778
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.766
positive regulation of lymphocyte activation GO:0051251 140 0.757
negative t cell selection GO:0043383 13 0.735
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.735
regulation of mast cell degranulation GO:0043304 16 0.721
leukocyte mediated immunity GO:0002443 174 0.718
b cell differentiation GO:0030183 78 0.706
activation of immune response GO:0002253 138 0.688
positive regulation of type iii hypersensitivity GO:0001805 3 0.681
cellular zinc ion homeostasis GO:0006882 9 0.676
serotonin secretion by platelet GO:0002554 3 0.663
t cell receptor v d j recombination GO:0033153 5 0.652
myeloid cell activation involved in immune response GO:0002275 34 0.650
immune response regulating signaling pathway GO:0002764 125 0.645
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.644
immunoglobulin production GO:0002377 73 0.632
immunoglobulin mediated immune response GO:0016064 69 0.626
alpha beta t cell differentiation GO:0046632 69 0.623
leukocyte homeostasis GO:0001776 79 0.617
myeloid leukocyte activation GO:0002274 83 0.613
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.609
cellular amino acid metabolic process GO:0006520 103 0.603
lymphocyte proliferation GO:0046651 164 0.570
positive regulation of isotype switching to igg isotypes GO:0048304 7 0.564
response to platelet derived growth factor GO:0036119 6 0.542
regulation of leukocyte proliferation GO:0070663 121 0.540
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.529
cytokine production GO:0001816 319 0.526
somatic diversification of immune receptors GO:0002200 53 0.523
regulation of cell killing GO:0031341 40 0.521
t cell mediated cytotoxicity GO:0001913 26 0.513
peptidyl amino acid modification GO:0018193 336 0.506
regulation of exocytosis GO:0017157 61 0.505
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.499
positive regulation of phospholipase c activity GO:0010863 2 0.491
positive regulation of secretion GO:0051047 130 0.489
amine metabolic process GO:0009308 45 0.486
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.483
neutrophil activation GO:0042119 9 0.475
dna recombination GO:0006310 92 0.468
alpha beta t cell activation GO:0046631 91 0.465
positive regulation of cellular amine metabolic process GO:0033240 5 0.461
regulation of alpha beta t cell activation GO:0046634 53 0.460
regulation of platelet activation GO:0010543 17 0.444
regulation of b cell differentiation GO:0045577 23 0.438
adaptive immune response GO:0002250 155 0.434
apoptotic signaling pathway GO:0097190 306 0.431
exocytosis GO:0006887 121 0.423
interleukin 4 production GO:0032633 24 0.423
regulation of leukocyte mediated immunity GO:0002703 104 0.412
granulocyte activation GO:0036230 10 0.412
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.409
regulation of lymphocyte differentiation GO:0045619 107 0.404
positive regulation of t cell activation GO:0050870 101 0.400
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.398
positive regulation of lymphocyte differentiation GO:0045621 61 0.397
positive thymic t cell selection GO:0045059 13 0.397
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.396
metal ion homeostasis GO:0055065 189 0.392
actin cytoskeleton organization GO:0030036 220 0.389
peptidyl tyrosine phosphorylation GO:0018108 143 0.384
v d j recombination GO:0033151 14 0.370
response to oxidative stress GO:0006979 123 0.366
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.366
lymphocyte anergy GO:0002249 4 0.363
platelet degranulation GO:0002576 6 0.359
muscle contraction GO:0006936 101 0.352
b cell mediated immunity GO:0019724 71 0.350
regulation of adaptive immune response GO:0002819 90 0.350
cytokine mediated signaling pathway GO:0019221 115 0.350
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 17 0.344
regulation of immunoglobulin production GO:0002637 42 0.344
interferon gamma production GO:0032609 67 0.328
lymphocyte homeostasis GO:0002260 64 0.328
calcium ion transport into cytosol GO:0060402 48 0.325
negative regulation of cell activation GO:0050866 111 0.323
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.319
neutrophil activation involved in immune response GO:0002283 8 0.316
peptidyl tyrosine modification GO:0018212 145 0.315
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.315
fc epsilon receptor signaling pathway GO:0038095 3 0.313
regulation of cellular amine metabolic process GO:0033238 20 0.310
positive regulation of b cell activation GO:0050871 49 0.309
fc receptor mediated stimulatory signaling pathway GO:0002431 4 0.307
somatic recombination of t cell receptor gene segments GO:0002681 5 0.307
hemostasis GO:0007599 78 0.302
gamma delta t cell differentiation GO:0042492 11 0.302
b cell receptor signaling pathway GO:0050853 20 0.301
regulation of homotypic cell cell adhesion GO:0034110 13 0.299
t cell anergy GO:0002870 4 0.298
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.297
regulation of cytokine production GO:0001817 266 0.294
regulation of leukocyte differentiation GO:1902105 159 0.292
positive regulation of t cell differentiation GO:0045582 52 0.290
cell activation involved in immune response GO:0002263 126 0.282
response to molecule of bacterial origin GO:0002237 143 0.281
somatic cell dna recombination GO:0016444 51 0.281
production of molecular mediator of immune response GO:0002440 103 0.279
regulation of t cell differentiation GO:0045580 83 0.275
organelle localization GO:0051640 179 0.273
regulation of ion transport GO:0043269 215 0.269
regulation of map kinase activity GO:0043405 120 0.267
cellular lipid metabolic process GO:0044255 323 0.265
cytokine secretion GO:0050663 72 0.264
cell killing GO:0001906 67 0.262
lymphocyte apoptotic process GO:0070227 54 0.260
platelet aggregation GO:0070527 20 0.244
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 9 0.243
blood coagulation GO:0007596 76 0.243
positive regulation of podosome assembly GO:0071803 3 0.239
regulation of lymphocyte proliferation GO:0050670 117 0.239
kit signaling pathway GO:0038109 3 0.237
regulation of ion homeostasis GO:2000021 64 0.237
cell fate commitment GO:0045165 210 0.235
positive regulation of cytokine production GO:0001819 174 0.234
regulation of t cell receptor signaling pathway GO:0050856 21 0.231
gland development GO:0048732 330 0.228
cellular glucan metabolic process GO:0006073 32 0.225
negative regulation of cell adhesion involved in substrate bound cell migration GO:0006933 3 0.225
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.222
serotonin production involved in inflammatory response GO:0002351 4 0.221
negative regulation of protein autophosphorylation GO:0031953 2 0.218
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.218
somatic diversification of t cell receptor genes GO:0002568 5 0.218
positive regulation of adaptive immune response GO:0002821 61 0.216
negative regulation of t cell mediated immunity GO:0002710 9 0.214
t cell proliferation GO:0042098 120 0.213
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045425 2 0.209
defense response to bacterium GO:0042742 119 0.208
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.206
positive regulation of leukocyte degranulation GO:0043302 10 0.206
b cell activation involved in immune response GO:0002312 50 0.205
regulation of regulatory t cell differentiation GO:0045589 7 0.205
lymphocyte activation involved in immune response GO:0002285 93 0.204
granulocyte differentiation GO:0030851 17 0.202
endodermal cell fate specification GO:0001714 4 0.199
organic acid biosynthetic process GO:0016053 86 0.198
negative regulation of lymphocyte activation GO:0051250 91 0.196
positive regulation of intracellular transport GO:0032388 70 0.196
myeloid cell homeostasis GO:0002262 114 0.196
cellular ketone metabolic process GO:0042180 84 0.195
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.194
regulation of b cell activation GO:0050864 81 0.194
isotype switching to igg isotypes GO:0048291 10 0.189
regulation of cd24 biosynthetic process GO:2000559 1 0.188
negative regulation of homeostatic process GO:0032845 71 0.186
single organismal cell cell adhesion GO:0016337 131 0.186
antigen processing and presentation of peptide antigen GO:0048002 29 0.178
positive regulation of mast cell degranulation GO:0043306 10 0.177
regulation of t cell activation GO:0050863 170 0.177
Human
protein autophosphorylation GO:0046777 61 0.177
positive regulation of regulated secretory pathway GO:1903307 10 0.175
interleukin 2 mediated signaling pathway GO:0038110 2 0.173
dna metabolic process GO:0006259 303 0.172
positive regulation of lymphocyte anergy GO:0002913 4 0.172
gamma delta t cell activation GO:0046629 13 0.169
myeloid leukocyte mediated immunity GO:0002444 42 0.166
modulation by virus of host process GO:0019054 2 0.164
response to peptide hormone GO:0043434 127 0.163
coagulation GO:0050817 78 0.163
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.162
fc receptor signaling pathway GO:0038093 6 0.160
positive regulation of mast cell activation involved in immune response GO:0033008 10 0.158
neuroblast fate determination GO:0007400 1 0.158
cation transport GO:0006812 399 0.157
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.154
cellular response to interleukin 15 GO:0071350 2 0.150
negative regulation of synapse assembly GO:0051964 3 0.149
negative regulation of immune effector process GO:0002698 55 0.148
response to lipopolysaccharide GO:0032496 128 0.148
regulation of intracellular transport GO:0032386 159 0.148
regulation of cytokine biosynthetic process GO:0042035 59 0.148
fatty acid biosynthetic process GO:0006633 41 0.147
positive regulation of b cell differentiation GO:0045579 13 0.147
negative regulation of b cell activation GO:0050869 27 0.147
negative regulation of adaptive immune response GO:0002820 25 0.145
leukocyte apoptotic process GO:0071887 71 0.145
regulation of type iia hypersensitivity GO:0001796 4 0.144
regulation of cellular amino acid metabolic process GO:0006521 5 0.143
positive regulation of t cell proliferation GO:0042102 52 0.143
positive regulation of mast cell activation GO:0033005 12 0.140
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.140
positive regulation of cell activation GO:0050867 158 0.140
positive regulation of cell killing GO:0031343 33 0.139
positive regulation of lymphocyte proliferation GO:0050671 70 0.138
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.138
positive regulation of secretion by cell GO:1903532 114 0.137
jnk cascade GO:0007254 72 0.136
platelet activation GO:0030168 40 0.135
positive regulation of apoptotic signaling pathway GO:2001235 95 0.134
positive regulation of programmed cell death GO:0043068 218 0.134
alpha beta t cell proliferation GO:0046633 21 0.134
positive regulation of jun kinase activity GO:0043507 30 0.132
bone remodeling GO:0046849 53 0.132
negative regulation of immune system process GO:0002683 209 0.128
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.126
calcium mediated signaling GO:0019722 46 0.125
Human
mast cell degranulation GO:0043303 19 0.125
b 1a b cell differentiation GO:0002337 2 0.124
regulation of secretion GO:0051046 274 0.123
protein localization to membrane GO:0072657 108 0.121
intestinal epithelial cell differentiation GO:0060575 14 0.121
positive regulation of stress activated mapk cascade GO:0032874 48 0.121
leukocyte degranulation GO:0043299 27 0.121
leukocyte activation involved in immune response GO:0002366 126 0.118
regulation of secretion by cell GO:1903530 249 0.118
cellular response to cytokine stimulus GO:0071345 189 0.115
regulation of dendritic cell apoptotic process GO:2000668 3 0.114
antigen processing and presentation of exogenous antigen GO:0019884 26 0.114
positive regulation of t cell mediated immunity GO:0002711 24 0.114
immune effector process GO:0002252 321 0.112
nk t cell differentiation GO:0001865 8 0.112
negative regulation of leukocyte differentiation GO:1902106 51 0.110
positive regulation of cytokine secretion GO:0050715 41 0.109
positive regulation of t cell anergy GO:0002669 4 0.109
regulation of phospholipase c activity GO:1900274 3 0.109
positive regulation of type ii hypersensitivity GO:0002894 4 0.109
regulation of response to wounding GO:1903034 189 0.108
protein secretion GO:0009306 111 0.108
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 17 0.107
homeostasis of number of cells GO:0048872 210 0.107
regulation of b cell proliferation GO:0030888 39 0.105
regulation of t cell mediated immunity GO:0002709 34 0.105
positive regulation of alpha beta t cell activation GO:0046635 39 0.104
positive regulation of mapk cascade GO:0043410 170 0.104
t cell mediated immunity GO:0002456 50 0.104
regulation of interleukin 2 production GO:0032663 28 0.104
positive regulation of interleukin 13 production GO:0032736 4 0.103
inflammatory response to antigenic stimulus GO:0002437 30 0.103
intracellular mrna localization GO:0008298 4 0.102
small molecule biosynthetic process GO:0044283 132 0.102
positive regulation of b cell receptor signaling pathway GO:0050861 4 0.101
canonical wnt signaling pathway GO:0060070 130 0.101
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.099
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.099
nucleolus organization GO:0007000 5 0.098
mucosal associated lymphoid tissue development GO:0048537 12 0.098
insulin receptor signaling pathway via phosphatidylinositol 3 kinase GO:0038028 3 0.095
positive regulation of cd4 positive cd25 positive alpha beta regulatory t cell differentiation GO:0032831 2 0.095
b cell proliferation GO:0042100 53 0.095
integrin mediated signaling pathway GO:0007229 27 0.094
Human
positive regulation of kinase activity GO:0033674 155 0.093
regulation of lymphocyte mediated immunity GO:0002706 84 0.092
zinc ion homeostasis GO:0055069 10 0.091
regulation of interleukin 8 secretion GO:2000482 2 0.090
regulation of gamma delta t cell activation GO:0046643 9 0.089
interleukin 8 secretion GO:0072606 3 0.089
cellular response to molecule of bacterial origin GO:0071219 83 0.088
regulation of alpha beta t cell proliferation GO:0046640 18 0.088
osteoclast differentiation GO:0030316 62 0.086
endomembrane system organization GO:0010256 147 0.086
regulation of smooth muscle contraction GO:0006940 22 0.086
regulation of interleukin 10 production GO:0032653 21 0.084
cytokine metabolic process GO:0042107 71 0.084
cofactor transport GO:0051181 4 0.082
inflammatory response GO:0006954 244 0.081
microtubule based process GO:0007017 236 0.080
neutrophil differentiation GO:0030223 3 0.078
homotypic cell cell adhesion GO:0034109 28 0.078
regulation of interleukin 8 production GO:0032677 3 0.077
membrane organization GO:0061024 245 0.077
immune response inhibiting signal transduction GO:0002765 4 0.076
positive regulation of protein phosphorylation GO:0001934 242 0.076
negative regulation of t cell activation GO:0050868 65 0.076
regulation of stress activated mapk cascade GO:0032872 69 0.076
regulation of leukocyte apoptotic process GO:2000106 56 0.076
b cell activation GO:0042113 161 0.075
negative regulation of protein metabolic process GO:0051248 282 0.074
response to morphine GO:0043278 9 0.073
organic hydroxy compound transport GO:0015850 93 0.073
striated muscle tissue development GO:0014706 293 0.072
regulation of immunoglobulin mediated immune response GO:0002889 37 0.071
regulation of system process GO:0044057 200 0.070
protein kinase b signaling GO:0043491 74 0.070
cd4 positive alpha beta t cell activation GO:0035710 45 0.070
t cell differentiation involved in immune response GO:0002292 30 0.069
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.069
positive regulation of immune effector process GO:0002699 107 0.067
positive regulation of leukocyte mediated immunity GO:0002705 70 0.066
positive regulation of t cell differentiation in thymus GO:0033089 13 0.064
muscle cell development GO:0055001 133 0.064
regulation of cytokine production involved in immune response GO:0002718 26 0.063
phospholipid metabolic process GO:0006644 87 0.063
actin filament bundle assembly GO:0051017 40 0.063
negative regulation of t cell apoptotic process GO:0070233 18 0.062
fc receptor mediated inhibitory signaling pathway GO:0002774 1 0.062
regulation of jnk cascade GO:0046328 62 0.062
response to stem cell factor GO:0036215 3 0.061
leukocyte migration GO:0050900 124 0.060
positive regulation of leukocyte proliferation GO:0070665 73 0.060
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.059
regulation of type iii hypersensitivity GO:0001803 3 0.059
striated muscle cell development GO:0055002 125 0.059
regulation of tissue remodeling GO:0034103 38 0.059
regulation of lipase activity GO:0060191 15 0.058
regulation of t cell differentiation in thymus GO:0033081 24 0.058
positive regulation of interleukin 8 secretion GO:2000484 1 0.058
regulation of body fluid levels GO:0050878 162 0.058
calcium ion transport GO:0006816 159 0.058
single organism cell adhesion GO:0098602 156 0.057
response to growth factor GO:0070848 198 0.056
calcium ion homeostasis GO:0055074 127 0.056
erk1 and erk2 cascade GO:0070371 77 0.056
regulation of vesicle mediated transport GO:0060627 139 0.055
t cell tolerance induction GO:0002517 6 0.055
positive regulation of protein kinase activity GO:0045860 144 0.055
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.054
interleukin 6 production GO:0032635 58 0.054
cytokine biosynthetic process GO:0042089 68 0.054
response to organonitrogen compound GO:0010243 246 0.054
cellular ion homeostasis GO:0006873 165 0.054
oocyte construction GO:0007308 2 0.054
negative regulation of interleukin 2 biosynthetic process GO:0045085 3 0.053
positive regulation of phagocytosis GO:0050766 26 0.053
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.053
hypersensitivity GO:0002524 10 0.052
regulation of apoptotic signaling pathway GO:2001233 197 0.051
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 3 0.051
positive regulation of protein modification process GO:0031401 299 0.051
olfactory learning GO:0008355 2 0.051
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.050
extrinsic apoptotic signaling pathway GO:0097191 126 0.050
regulation of protein localization GO:0032880 231 0.050
cellular protein complex assembly GO:0043623 116 0.050
fatty acid metabolic process GO:0006631 121 0.050
regulation of interleukin 6 production GO:0032675 55 0.050
regulation of hypersensitivity GO:0002883 10 0.049
positive regulation of transferase activity GO:0051347 167 0.049
substrate adhesion dependent cell spreading GO:0034446 30 0.048
endoderm formation GO:0001706 20 0.048
establishment of organelle localization GO:0051656 122 0.048
cell type specific apoptotic process GO:0097285 268 0.048
transition metal ion homeostasis GO:0055076 54 0.047
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 14 0.047
regulation of jun kinase activity GO:0043506 40 0.047
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.047
divalent metal ion transport GO:0070838 172 0.046
regulation of tumor necrosis factor production GO:0032680 49 0.046
positive regulation of interferon gamma production GO:0032729 39 0.046
icosanoid biosynthetic process GO:0046456 15 0.046
regulation of myeloid cell differentiation GO:0045637 96 0.045
regulation of endocytosis GO:0030100 69 0.045
regulation of anion transport GO:0044070 27 0.044
regulation of b cell mediated immunity GO:0002712 37 0.044
positive regulation of interleukin 6 production GO:0032755 37 0.044
regulation of mast cell proliferation GO:0070666 4 0.044
regulation of cysteine type endopeptidase activity GO:2000116 65 0.043
regulation of production of molecular mediator of immune response GO:0002700 65 0.043
immunoglobulin secretion GO:0048305 17 0.042
positive regulation of translational initiation GO:0045948 4 0.042
cellular response to organonitrogen compound GO:0071417 145 0.042
positive regulation of type i hypersensitivity GO:0001812 3 0.042
mapk cascade GO:0000165 281 0.042
regulated secretory pathway GO:0045055 32 0.041
positive regulation of amino acid transport GO:0051957 4 0.041
carboxylic acid biosynthetic process GO:0046394 86 0.041
positive regulation of phospholipase activity GO:0010518 3 0.041
cytosolic calcium ion homeostasis GO:0051480 70 0.041
regulation of inflammatory response GO:0050727 147 0.041
negative regulation of map kinase activity GO:0043407 34 0.041
positive regulation of hydrolase activity GO:0051345 148 0.040
insulin metabolic process GO:1901142 3 0.040
negative regulation of response to wounding GO:1903035 77 0.040
regulation of protein serine threonine kinase activity GO:0071900 157 0.040
cellular response to biotic stimulus GO:0071216 92 0.040
myeloid leukocyte differentiation GO:0002573 119 0.040
regulation of leukocyte degranulation GO:0043300 20 0.039
regulation of neutrophil differentiation GO:0045658 2 0.039
cellular response to hormone stimulus GO:0032870 150 0.039
monocyte extravasation GO:0035696 2 0.039
gene looping GO:0090202 2 0.039
regulation of isotype switching to igg isotypes GO:0048302 10 0.039
carboxylic acid transport GO:0046942 100 0.039
cellular response to stem cell factor stimulus GO:0036216 3 0.038
regulation of monocyte extravasation GO:2000437 2 0.038
negative regulation of toll like receptor 2 signaling pathway GO:0034136 3 0.037
regulation of binding GO:0051098 111 0.037
cation transmembrane transport GO:0098655 266 0.036
regulation of actin cytoskeleton organization GO:0032956 84 0.036
neuron projection guidance GO:0097485 141 0.036
negative regulation of protein phosphorylation GO:0001933 126 0.036
cellularization GO:0007349 1 0.036
positive regulation of leukocyte apoptotic process GO:2000108 21 0.036
adherens junction organization GO:0034332 28 0.036
positive regulation of map kinase activity GO:0043406 84 0.036
oocyte anterior posterior axis specification GO:0007314 2 0.036
apical constriction GO:0003383 4 0.035
transmembrane transport GO:0055085 412 0.035
serotonin secretion GO:0001820 8 0.035
regulation of calcium mediated signaling GO:0050848 19 0.035
negative regulation of apoptotic signaling pathway GO:2001234 104 0.035
protein localization to plasma membrane GO:0072659 57 0.035
regulation of protein binding GO:0043393 60 0.035
tumor necrosis factor production GO:0032640 50 0.035
monoamine transport GO:0015844 33 0.034
regulation of cd4 positive cd25 positive alpha beta regulatory t cell differentiation GO:0032829 2 0.034
reactive oxygen species metabolic process GO:0072593 84 0.034
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.034
b 1 b cell differentiation GO:0001923 3 0.034
sensory perception GO:0007600 245 0.033
filtration diaphragm assembly GO:0036058 1 0.033
positive regulation of cd24 biosynthetic process GO:2000560 1 0.033
somatic diversification of immunoglobulins GO:0016445 43 0.033
regulation of bone resorption GO:0045124 24 0.033
regulation of muscle system process GO:0090257 80 0.033
cell adhesion GO:0007155 329 0.033
microtubule cytoskeleton organization GO:0000226 157 0.033
defense response to other organism GO:0098542 197 0.032
positive regulation of cytokine biosynthetic process GO:0042108 40 0.032
eosinophil differentiation GO:0030222 1 0.032
regulation of interferon gamma production GO:0032649 57 0.032
erythrocyte differentiation GO:0030218 88 0.032
regulation of hydrolase activity GO:0051336 246 0.032
regulation of endopeptidase activity GO:0052548 89 0.032
regulation of dna recombination GO:0000018 34 0.032
plasma membrane organization GO:0007009 90 0.032
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.032
regulation of hemostasis GO:1900046 28 0.032
activation of phospholipase c activity GO:0007202 2 0.032
regulation of blood coagulation GO:0030193 28 0.031
negative regulation of b cell mediated immunity GO:0002713 7 0.031
peptidyl serine phosphorylation GO:0018105 74 0.031
production of molecular mediator involved in inflammatory response GO:0002532 21 0.031
regulation of hematopoietic stem cell migration GO:2000471 1 0.031
nitrogen compound transport GO:0071705 271 0.031
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.030
negative regulation of mast cell apoptotic process GO:0033026 4 0.030
negative regulation of toll like receptor 4 signaling pathway GO:0034144 3 0.030
exocrine system development GO:0035272 45 0.030
organelle assembly GO:0070925 177 0.030
regulation of platelet aggregation GO:0090330 10 0.030
regulation of kinase activity GO:0043549 249 0.030
regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000702 1 0.030
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.030
regulation of lymphocyte apoptotic process GO:0070228 41 0.030
regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045423 2 0.030
tissue homeostasis GO:0001894 115 0.030
negative regulation of t helper 1 cell differentiation GO:0045626 3 0.030
cellular metal ion homeostasis GO:0006875 151 0.029
granulocyte macrophage colony stimulating factor biosynthetic process GO:0042253 2 0.029

Lat disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.825
disease of anatomical entity DOID:7 0 0.825
primary immunodeficiency disease DOID:612 0 0.805
severe combined immunodeficiency DOID:627 0 0.805
combined t cell and b cell immunodeficiency DOID:628 0 0.805
disease of metabolism DOID:0014667 0 0.288
acquired metabolic disease DOID:0060158 0 0.288
hypersensitivity reaction disease DOID:0060056 0 0.137
bone inflammation disease DOID:3342 0 0.120
bone disease DOID:0080001 0 0.120
rheumatoid arthritis DOID:7148 0 0.120
musculoskeletal system disease DOID:17 0 0.120
connective tissue disease DOID:65 0 0.120
arthritis DOID:848 0 0.120
nervous system disease DOID:863 0 0.032
hypersensitivity reaction type ii disease DOID:417 0 0.031
retinal disease DOID:5679 0 0.030
retinal degeneration DOID:8466 0 0.030
sensory system disease DOID:0050155 0 0.030
eye and adnexa disease DOID:1492 0 0.030
eye disease DOID:5614 0 0.030