IMP

Process View

Mus musculus

0 genes annotated in mouse

hypersensitivity reaction disease

DOID:0060056

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "hypersensitivity reaction disease" (in gray)

Name	Description	Probability	Func Analog Organism
Cd19	CD19 antigen	0.882
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.854	Human
Ptprc	protein tyrosine phosphatase, receptor type, C	0.854
Ifng	interferon gamma	0.810
Lyz2	lysozyme 2	0.761
Fas	Fas (TNF receptor superfamily member 6)	0.628	Human
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.292
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.286
Ifngr1	interferon gamma receptor 1	0.254
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.240
Il10	interleukin 10	0.232
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.221
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.214
Tnip1	TNFAIP3 interacting protein 1	0.188
Fasl	Fas ligand (TNF superfamily, member 6)	0.170	Human
Apoe	apolipoprotein E	0.161
Casp8	caspase 8	0.152
Foxp3	forkhead box P3	0.139
Lat	linker for activation of T cells	0.137
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.136
Pdcd1	programmed cell death 1	0.134	Human
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.122
Icos	inducible T-cell co-stimulator	0.116
H2-Eb1	histocompatibility 2, class II antigen E beta	0.115
Itk	IL2-inducible T-cell kinase	0.103
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.094	Human
Traf3ip2	TRAF3 interacting protein 2	0.082
Inpp5d	inositol polyphosphate-5-phosphatase D	0.071
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.069
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.066
Prkcd	protein kinase C, delta	0.064
Csf1r	colony stimulating factor 1 receptor	0.063
Cd274	CD274 antigen	0.052
Chst14	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14	0.048
B2m	beta-2 microglobulin	0.042
Zap70	zeta-chain (TCR) associated protein kinase	0.042
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.042
Gimap7	GTPase, IMAP family member 7	0.041
Cd28	CD28 antigen	0.041
Cd22	CD22 antigen	0.039
Il2rb	interleukin 2 receptor, beta chain	0.038
C3	complement component 3	0.035
Egr2	early growth response 2	0.035
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.032
Ly86	lymphocyte antigen 86	0.031
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.031
Socs1	suppressor of cytokine signaling 1	0.031
Cd96	CD96 antigen	0.031
Rasgrp1	RAS guanyl releasing protein 1	0.030
Ccr1	chemokine (C-C motif) receptor 1	0.029
Cd40	CD40 antigen	0.029
Ikzf3	IKAROS family zinc finger 3	0.029
Cd7	CD7 antigen	0.028
C1qb	complement component 1, q subcomponent, beta polypeptide	0.027
Selp	selectin, platelet	0.027
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.027
Il1r2	interleukin 1 receptor, type II	0.026
Lair1	leukocyte-associated Ig-like receptor 1	0.026
Ccr7	chemokine (C-C motif) receptor 7	0.025
Hmox1	heme oxygenase (decycling) 1	0.024
Ccl5	chemokine (C-C motif) ligand 5	0.023
Cd3g	CD3 antigen, gamma polypeptide	0.022
H2-Eb2	histocompatibility 2, class II antigen E beta2	0.021
Cav1	caveolin 1, caveolae protein	0.021
Dennd5a	DENN/MADD domain containing 5A	0.021
Ciita	class II transactivator	0.021
Il2	interleukin 2	0.020
Sh2d2a	SH2 domain protein 2A	0.020
Cxcl9	chemokine (C-X-C motif) ligand 9	0.020
Slamf1	signaling lymphocytic activation molecule family member 1	0.020
Myl9	myosin, light polypeptide 9, regulatory	0.020
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.019	Human
Cd6	CD6 antigen	0.019
Cd5	CD5 antigen	0.018
Tmbim1	transmembrane BAX inhibitor motif containing 1	0.017
Sykb	spleen tyrosine kinase	0.017
Nab2	Ngfi-A binding protein 2	0.017
Irf8	interferon regulatory factor 8	0.017
Tlr7	toll-like receptor 7	0.016
Lta	lymphotoxin A	0.016
Lag3	lymphocyte-activation gene 3	0.016
Cd3e	CD3 antigen, epsilon polypeptide	0.016
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.015
Il6st	interleukin 6 signal transducer	0.015
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.015
Lyz1	lysozyme 1	0.015
Blk	B lymphoid kinase	0.015
Ccr8	chemokine (C-C motif) receptor 8	0.015
Bach2	BTB and CNC homology 2	0.015
Il27ra	interleukin 27 receptor, alpha	0.015
Mt2	metallothionein 2	0.015
Irf4	interferon regulatory factor 4	0.014
Ctsw	cathepsin W	0.014
Itgb2	integrin beta 2	0.014
Nab1	Ngfi-A binding protein 1	0.014
Il4ra	interleukin 4 receptor, alpha	0.014
Krtap26-1	keratin associated protein 26-1	0.014
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.014
Ccl4	chemokine (C-C motif) ligand 4	0.013
Gabrr1	gamma-aminobutyric acid (GABA) C receptor, subunit rho 1	0.013
Arhgap17	Rho GTPase activating protein 17	0.013
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.013
Il2ra	interleukin 2 receptor, alpha chain	0.013
Cxcr3	chemokine (C-X-C motif) receptor 3	0.013
Ccl17	chemokine (C-C motif) ligand 17	0.013
Id3	inhibitor of DNA binding 3	0.013
Nup62-il4i1	Nup62-Il4i1 protein	0.013
Cd300ld	CD300 molecule-like family member d	0.013
Itgax	integrin alpha X	0.013
Gm614	predicted gene 614	0.013
Gzma	granzyme A	0.013
Ccl9	chemokine (C-C motif) ligand 9	0.013
Il4	interleukin 4	0.012
Cxcr2	chemokine (C-X-C motif) receptor 2	0.012
P2ry12	purinergic receptor P2Y, G-protein coupled 12	0.012
H2-Q7	histocompatibility 2, Q region locus 7	0.012
Rel	reticuloendotheliosis oncogene	0.012
Fcgr4	Fc receptor, IgG, low affinity IV	0.012
Gpr132	G protein-coupled receptor 132	0.012
Fcgr1	Fc receptor, IgG, high affinity I	0.012
Cd86	CD86 antigen	0.012
Itga1	integrin alpha 1	0.012
Gimap3	GTPase, IMAP family member 3	0.012
Cytip	cytohesin 1 interacting protein	0.012
Xcr1	chemokine (C motif) receptor 1	0.011
Tlr4	toll-like receptor 4	0.011
Sparc	secreted acidic cysteine rich glycoprotein	0.011
Plcg2	phospholipase C, gamma 2	0.011
Stat4	signal transducer and activator of transcription 4	0.011
Il1r1	interleukin 1 receptor, type I	0.011
Cst7	cystatin F (leukocystatin)	0.011
C3ar1	complement component 3a receptor 1	0.011
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.011
Cfh	complement component factor h	0.011
Nos2	nitric oxide synthase 2, inducible	0.011
C1qc	complement component 1, q subcomponent, C chain	0.011
Sla	src-like adaptor	0.011
Fyn	Fyn proto-oncogene	0.011
Clec4n	C-type lectin domain family 4, member n	0.011
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.011
Mpeg1	macrophage expressed gene 1	0.011
Derl3	Der1-like domain family, member 3	0.011
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.011
Lax1	lymphocyte transmembrane adaptor 1	0.011
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.010
Txk	TXK tyrosine kinase	0.010
Jak1	Janus kinase 1	0.010
H2-DMa	histocompatibility 2, class II, locus DMa	0.010
Hoxa13	homeobox A13	0.010
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.010
Sh2d1a	SH2 domain protein 1A	0.010