IMP

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Mus musculus

24 genes annotated in mouse

Multi-species View

regulation of t cell differentiation in thymus

GO:0033081

Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of t cell differentiation in thymus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of t cell differentiation in thymus" (in gray)

Name	Description	Probability	Func Analog Organism
Gli2	GLI-Kruppel family member GLI2	0.986
Rybp	RING1 and YY1 binding protein	0.977
Gli3	GLI-Kruppel family member GLI3	0.954	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.903
Shh	sonic hedgehog	0.864
Rnf2	ring finger protein 2	0.806
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.702
Tgfb2	transforming growth factor, beta 2	0.641
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.641	Mouse
Sox9	SRY-box containing gene 9	0.531
Foxc1	forkhead box C1	0.494
Apc	adenomatosis polyposis coli	0.433
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.365
Grb2	growth factor receptor bound protein 2	0.355
Cd247	CD247 antigen	0.334
Egr2	early growth response 2	0.263	Mouse
Ptch1	patched homolog 1	0.247
Adam12	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	0.236	Mouse
Meox2	mesenchyme homeobox 2	0.234
Ren1	renin 1 structural	0.209
Fgf10	fibroblast growth factor 10	0.203
Ntf3	neurotrophin 3	0.196
Egfr	epidermal growth factor receptor	0.191	Mouse
Foxc2	forkhead box C2	0.182
Smad4	MAD homolog 4 (Drosophila)	0.158
Prrx1	paired related homeobox 1	0.157
Ptgs2	prostaglandin-endoperoxide synthase 2	0.138
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.121
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.119	Mouse
Rarg	retinoic acid receptor, gamma	0.118
Pthlh	parathyroid hormone-like peptide	0.113
Gata4	GATA binding protein 4	0.113
Phc2	polyhomeotic-like 2 (Drosophila)	0.108
Egr1	early growth response 1	0.105	Mouse
Pax6	paired box gene 6	0.105
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.101
Ctnnb1	catenin (cadherin associated protein), beta 1	0.101
Tcra	T-cell receptor alpha chain	0.098
Smo	smoothened homolog (Drosophila)	0.095
Nrg1	neuregulin 1	0.093
Nf1	neurofibromatosis 1	0.091
Trp53	transformation related protein 53	0.087
Jak2	Janus kinase 2	0.083
Socs3	suppressor of cytokine signaling 3	0.082
Trp63	transformation related protein 63	0.081
Pitx2	paired-like homeodomain transcription factor 2	0.081
Ar	androgen receptor	0.079
Twist2	twist homolog 2 (Drosophila)	0.079
Nab2	Ngfi-A binding protein 2	0.078
Kif19a	kinesin family member 19A	0.072
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.070
Col2a1	collagen, type II, alpha 1	0.069
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.069
Chrd	chordin	0.068
Lepr	leptin receptor	0.068
Ikzf1	IKAROS family zinc finger 1	0.064
Bmp4	bone morphogenetic protein 4	0.063	Human
Zeb1	zinc finger E-box binding homeobox 1	0.062
Sos1	son of sevenless homolog 1 (Drosophila)	0.062
Bmi1	Bmi1 polycomb ring finger oncogene	0.060
Lat	linker for activation of T cells	0.058
Msx2	homeobox, msh-like 2	0.058
Pax3	paired box gene 3	0.055
Klf3	Kruppel-like factor 3 (basic)	0.054
Amhr2	anti-Mullerian hormone type 2 receptor	0.054
Isl1	ISL1 transcription factor, LIM/homeodomain	0.053
Hoxa1	homeobox A1	0.052
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.051
Ret	ret proto-oncogene	0.051
Ank1	ankyrin 1, erythroid	0.049
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.048
Vangl2	vang-like 2 (van gogh, Drosophila)	0.048
Runx2	runt related transcription factor 2	0.048
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.047
Fgf9	fibroblast growth factor 9	0.045
Adam15	a disintegrin and metallopeptidase domain 15 (metargidin)	0.045	Mouse
Kiss1	KiSS-1 metastasis-suppressor	0.044
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.043
Stat3	signal transducer and activator of transcription 3	0.043
Il2rg	interleukin 2 receptor, gamma chain	0.041
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.041
Fos	FBJ osteosarcoma oncogene	0.039
Gja1	gap junction protein, alpha 1	0.039
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.039
Foxn1	forkhead box N1	0.038
Cd44	CD44 antigen	0.038
Setdb1	SET domain, bifurcated 1	0.038
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.037
Foxf2	forkhead box F2	0.036
Il6st	interleukin 6 signal transducer	0.036
Junb	Jun-B oncogene	0.035
Mdm2	transformed mouse 3T3 cell double minute 2	0.035
Bmp7	bone morphogenetic protein 7	0.034
Fgfr3	fibroblast growth factor receptor 3	0.034
Kdm2b	lysine (K)-specific demethylase 2B	0.034
Rxra	retinoid X receptor alpha	0.034
Rara	retinoic acid receptor, alpha	0.033
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.033
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.033
Gli1	GLI-Kruppel family member GLI1	0.033	Mouse
Zfpm2	zinc finger protein, multitype 2	0.032
Bdnf	brain derived neurotrophic factor	0.032
Ptprc	protein tyrosine phosphatase, receptor type, C	0.032
Phox2b	paired-like homeobox 2b	0.030
Cbl	Casitas B-lineage lymphoma	0.030
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.029
Vhl	von Hippel-Lindau tumor suppressor	0.029
Tbk1	TANK-binding kinase 1	0.028
Fyn	Fyn proto-oncogene	0.028
Foxa2	forkhead box A2	0.026
Pten	phosphatase and tensin homolog	0.026
Tgfa	transforming growth factor alpha	0.026
Rag2	recombination activating gene 2	0.026
Sox4	SRY-box containing gene 4	0.026
Adam9	a disintegrin and metallopeptidase domain 9 (meltrin gamma)	0.025	Mouse
Lck	lymphocyte protein tyrosine kinase	0.025
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.025
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.024
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.024
Cbx8	chromobox homolog 8 (Drosophila Pc class)	0.024
Pax2	paired box gene 2	0.023
Phc1	polyhomeotic-like 1 (Drosophila)	0.023
Adam17	a disintegrin and metallopeptidase domain 17	0.023	Mouse
Bmper	BMP-binding endothelial regulator	0.023
Runx1	runt related transcription factor 1	0.023
Nab1	Ngfi-A binding protein 1	0.022
Hif1a	hypoxia inducible factor 1, alpha subunit	0.022
Gata6	GATA binding protein 6	0.022
Nos3	nitric oxide synthase 3, endothelial cell	0.022
Shc1	src homology 2 domain-containing transforming protein C1	0.022
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.021
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.021
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.021
Vegfa	vascular endothelial growth factor A	0.021
Bmp2	bone morphogenetic protein 2	0.021
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.021
Insm1	insulinoma-associated 1	0.021
Tgfbr2	transforming growth factor, beta receptor II	0.021
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.021
Jag1	jagged 1	0.021
Gata5	GATA binding protein 5	0.020
Rbms1	RNA binding motif, single stranded interacting protein 1	0.020
Fgfr1	fibroblast growth factor receptor 1	0.020
Kiss1r	KISS1 receptor	0.020
Jak3	Janus kinase 3	0.019
Scn5a	sodium channel, voltage-gated, type V, alpha	0.019
Smad1	MAD homolog 1 (Drosophila)	0.019
Ptch2	patched homolog 2	0.019
Rarb	retinoic acid receptor, beta	0.018
Csnk2a2	casein kinase 2, alpha prime polypeptide	0.018
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.018
Bcor	BCL6 interacting corepressor	0.018
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.018
Ddx54	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54	0.018
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.017
Abi1	abl-interactor 1	0.017
Col4a3	collagen, type IV, alpha 3	0.017
Pkd1	polycystic kidney disease 1 homolog	0.016
Emx2	empty spiracles homolog 2 (Drosophila)	0.016
Cyp11b2	cytochrome P450, family 11, subfamily b, polypeptide 2	0.016
Jak1	Janus kinase 1	0.016
Stxbp3a	syntaxin binding protein 3A	0.015
Kcnab3	potassium voltage-gated channel, shaker-related subfamily, beta member 3	0.015
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.015
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.015
Otx1	orthodenticle homolog 1 (Drosophila)	0.015
Dlx5	distal-less homeobox 5	0.015
Smad3	MAD homolog 3 (Drosophila)	0.015
Tcf21	transcription factor 21	0.015
Klf1	Kruppel-like factor 1 (erythroid)	0.015
Ltbp2	latent transforming growth factor beta binding protein 2	0.015
Lhx3	LIM homeobox protein 3	0.014
Mpl	myeloproliferative leukemia virus oncogene	0.014	Mouse
Psmd3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.014
Disp1	dispatched homolog 1 (Drosophila)	0.014
Otx2	orthodenticle homolog 2 (Drosophila)	0.014
Odf2	outer dense fiber of sperm tails 2	0.014
Kit	kit oncogene	0.014
Itga3	integrin alpha 3	0.014
Ttc7	tetratricopeptide repeat domain 7	0.014
Hoxa5	homeobox A5	0.014
Ctgf	connective tissue growth factor	0.014
Lhx1	LIM homeobox protein 1	0.014
Allc	allantoicase	0.014
Tgfb1	transforming growth factor, beta 1	0.014
Zbtb7c	zinc finger and BTB domain containing 7C	0.014
Kif3a	kinesin family member 3A	0.014
Bcl3	B-cell leukemia/lymphoma 3	0.014
Hbb-b1	hemoglobin, beta adult major chain	0.013
Fosb	FBJ osteosarcoma oncogene B	0.013
Col1a1	collagen, type I, alpha 1	0.013
Nf2	neurofibromatosis 2	0.013
Hoxa11	homeobox A11	0.013
Mdm4	transformed mouse 3T3 cell double minute 4	0.013
Lmx1a	LIM homeobox transcription factor 1 alpha	0.013
Ahr	aryl-hydrocarbon receptor	0.013
Hr	hairless	0.013
Noto	notochord homolog (Xenopus laevis)	0.013
Lmna	lamin A	0.013
Irf6	interferon regulatory factor 6	0.012
Lhx9	LIM homeobox protein 9	0.012
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.012
Zbtb33	zinc finger and BTB domain containing 33	0.012
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.012
Rad17	RAD17 homolog (S. pombe)	0.012
Arrb2	arrestin, beta 2	0.012
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.012
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.012
En1	engrailed 1	0.012
Bnc1	basonuclin 1	0.012
Thbs1	thrombospondin 1	0.012
Frs2	fibroblast growth factor receptor substrate 2	0.012
Sfn	stratifin	0.012
Hoxc9	homeobox C9	0.012
Aqp2	aquaporin 2	0.012
Braf	Braf transforming gene	0.012
Fcrla	Fc receptor-like A	0.012
Gdnf	glial cell line derived neurotrophic factor	0.012
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.012
Nog	noggin	0.012
Bmp8a	bone morphogenetic protein 8a	0.012
Wt1	Wilms tumor 1 homolog	0.012	Mouse
Efnb2	ephrin B2	0.012
Plaur	plasminogen activator, urokinase receptor	0.011
Bdkrb2	bradykinin receptor, beta 2	0.011
Treml1	triggering receptor expressed on myeloid cells-like 1	0.011
Nsf	N-ethylmaleimide sensitive fusion protein	0.011
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.011
Gtse1	G two S phase expressed protein 1	0.011
Stat5a	signal transducer and activator of transcription 5A	0.011
Errfi1	ERBB receptor feedback inhibitor 1	0.011
Mtl5	metallothionein-like 5, testis-specific (tesmin)	0.011
Hhex	hematopoietically expressed homeobox	0.011
Dad1	defender against cell death 1	0.011
Alx1	ALX homeobox 1	0.011
Kl	klotho	0.011
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.011
Hoxd13	homeobox D13	0.011
Vav2	vav 2 oncogene	0.011
Jup	junction plakoglobin	0.011
Tsc1	tuberous sclerosis 1	0.011
Efna4	ephrin A4	0.011
Il7r	interleukin 7 receptor	0.011
Stk11	serine/threonine kinase 11	0.011
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.011
Vdr	vitamin D receptor	0.010
Fstl1	follistatin-like 1	0.010
Hdac7	histone deacetylase 7	0.010
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.010
Lef1	lymphoid enhancer binding factor 1	0.010
Spna1	spectrin alpha 1	0.010
Slc35b1	solute carrier family 35, member B1	0.010
Hivep1	human immunodeficiency virus type I enhancer binding protein 1	0.010
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.010
Syt7	synaptotagmin VII	0.010
Wnt5a	wingless-related MMTV integration site 5A	0.010
Zic2	zinc finger protein of the cerebellum 2	0.010
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.010
Mark4	MAP/microtubule affinity-regulating kinase 4	0.010
Stat5b	signal transducer and activator of transcription 5B	0.010