IMP

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of inflammatory response to antigenic stimulus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of inflammatory response to antigenic stimulus" (in gray)

Name	Description	Probability	Func Analog Organism
Tnf	tumor necrosis factor	1.000
Ifng	interferon gamma	1.000
Lyz2	lysozyme 2	1.000
Cd19	CD19 antigen	0.999
Igh	immunoglobulin heavy chain complex	0.996
Il10	interleukin 10	0.991
Il4	interleukin 4	0.990
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.990
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.971
Ccr2	chemokine (C-C motif) receptor 2	0.968	Mouse
Cd44	CD44 antigen	0.967
Fas	Fas (TNF receptor superfamily member 6)	0.949
Tlr4	toll-like receptor 4	0.947
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.945
Ccr1	chemokine (C-C motif) receptor 1	0.939	Mouse
Lta	lymphotoxin A	0.937
Cd40	CD40 antigen	0.932
Foxp3	forkhead box P3	0.921
Icos	inducible T-cell co-stimulator	0.921	Mouse
Ikzf1	IKAROS family zinc finger 1	0.908
Cxcr5	chemokine (C-X-C motif) receptor 5	0.904	Mouse
Ptprc	protein tyrosine phosphatase, receptor type, C	0.868
Ccl2	chemokine (C-C motif) ligand 2	0.858
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.776
Prf1	perforin 1 (pore forming protein)	0.775
Cxcl13	chemokine (C-X-C motif) ligand 13	0.744
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.723
Ccr6	chemokine (C-C motif) receptor 6	0.694	Mouse
Ifngr1	interferon gamma receptor 1	0.666
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.655
Pdcd1	programmed cell death 1	0.647
Apoe	apolipoprotein E	0.616
Fasl	Fas ligand (TNF superfamily, member 6)	0.596	Mouse
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.541
Myd88	myeloid differentiation primary response gene 88	0.502
Tlr2	toll-like receptor 2	0.500
Nos2	nitric oxide synthase 2, inducible	0.491
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.475
Il2rg	interleukin 2 receptor, gamma chain	0.473
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.464
Inpp5d	inositol polyphosphate-5-phosphatase D	0.427
Il27ra	interleukin 27 receptor, alpha	0.421
Mmp9	matrix metallopeptidase 9	0.417
Cd28	CD28 antigen	0.405
Il1r1	interleukin 1 receptor, type I	0.396
Il1b	interleukin 1 beta	0.384
Blk	B lymphoid kinase	0.384
Ccr5	chemokine (C-C motif) receptor 5	0.381	Mouse
Xcr1	chemokine (C motif) receptor 1	0.375	Mouse
Gzmk	granzyme K	0.362
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.353
Prdm1	PR domain containing 1, with ZNF domain	0.350
Batf	basic leucine zipper transcription factor, ATF-like	0.344
Il2rb	interleukin 2 receptor, beta chain	0.331
Casp1	caspase 1	0.330
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.326
Il22	interleukin 22	0.308	Mouse
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.307
Il6	interleukin 6	0.307
Ciita	class II transactivator	0.292
C3	complement component 3	0.276
Il15	interleukin 15	0.263
Ccl4	chemokine (C-C motif) ligand 4	0.258
Btk	Bruton agammaglobulinemia tyrosine kinase	0.238
Il2	interleukin 2	0.232
Itk	IL2-inducible T-cell kinase	0.226
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.219
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.215	Mouse
Ltb	lymphotoxin B	0.175
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.175
C3ar1	complement component 3a receptor 1	0.163
C1qb	complement component 1, q subcomponent, beta polypeptide	0.155
Cd22	CD22 antigen	0.149
Ccl3	chemokine (C-C motif) ligand 3	0.147
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.147	Mouse
Gzmb	granzyme B	0.147
Il7	interleukin 7	0.144
Cxcr3	chemokine (C-X-C motif) receptor 3	0.138	Mouse
Selp	selectin, platelet	0.137
Cd96	CD96 antigen	0.126
Cxcr2	chemokine (C-X-C motif) receptor 2	0.122	Mouse
Crtam	cytotoxic and regulatory T cell molecule	0.120
Zap70	zeta-chain (TCR) associated protein kinase	0.116
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.115
Folr2	folate receptor 2 (fetal)	0.114
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.113
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.109
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.107
Cd40lg	CD40 ligand	0.107	Mouse
Pycard	PYD and CARD domain containing	0.104
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.102
Pou2af1	POU domain, class 2, associating factor 1	0.102
Mefv	Mediterranean fever	0.101
Gpr132	G protein-coupled receptor 132	0.101
Nlrp3	NLR family, pyrin domain containing 3	0.101	Mouse
Spp1	secreted phosphoprotein 1	0.100
Ubd	ubiquitin D	0.098
Sele	selectin, endothelial cell	0.097
Cd4	CD4 antigen	0.096
Il12rb2	interleukin 12 receptor, beta 2	0.096
Tcra	T-cell receptor alpha chain	0.095
Psma3	proteasome (prosome, macropain) subunit, alpha type 3	0.094
Cd7	CD7 antigen	0.093
Ncr1	natural cytotoxicity triggering receptor 1	0.090
Ccr7	chemokine (C-C motif) receptor 7	0.090
Cd3e	CD3 antigen, epsilon polypeptide	0.089
C1qc	complement component 1, q subcomponent, C chain	0.088
Iqcb1	IQ calmodulin-binding motif containing 1	0.082
Sh2d2a	SH2 domain protein 2A	0.081
Cd6	CD6 antigen	0.081
Itgb2	integrin beta 2	0.081
Il2ra	interleukin 2 receptor, alpha chain	0.079
Vpreb3	pre-B lymphocyte gene 3	0.078
Tox	thymocyte selection-associated high mobility group box	0.077
Tyrobp	TYRO protein tyrosine kinase binding protein	0.077
Ccr3	chemokine (C-C motif) receptor 3	0.076	Mouse
Pax5	paired box gene 5	0.075
Il6st	interleukin 6 signal transducer	0.074
Pabpc2	poly(A) binding protein, cytoplasmic 2	0.074
Art2a-ps	ADP-ribosyltransferase 2a, pseudogene	0.073
Il15ra	interleukin 15 receptor, alpha chain	0.072
Cd5	CD5 antigen	0.072
Socs1	suppressor of cytokine signaling 1	0.072
Itgal	integrin alpha L	0.072
Gbp1	guanylate binding protein 1	0.072
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.071	Mouse
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.069
Lyz1	lysozyme 1	0.067
Ccl8	chemokine (C-C motif) ligand 8	0.067
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.066
Cd86	CD86 antigen	0.064
Ooep	oocyte expressed protein homolog (dog)	0.063
Psma6	proteasome (prosome, macropain) subunit, alpha type 6	0.057
Cr2	complement receptor 2	0.055
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.052
Tbx21	T-box 21	0.051
Ccr9	chemokine (C-C motif) receptor 9	0.051	Mouse
Pdcd1lg2	programmed cell death 1 ligand 2	0.051
Id2	inhibitor of DNA binding 2	0.050
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.050
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.049
Ticam1	toll-like receptor adaptor molecule 1	0.049
Il18rap	interleukin 18 receptor accessory protein	0.048
Clec4n	C-type lectin domain family 4, member n	0.048
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.048
Il10ra	interleukin 10 receptor, alpha	0.048
Cxcl9	chemokine (C-X-C motif) ligand 9	0.048
Irf1	interferon regulatory factor 1	0.047
Cd180	CD180 antigen	0.047
Zp2	zona pellucida glycoprotein 2	0.046
Aicda	activation-induced cytidine deaminase	0.045
Folr4	folate receptor 4 (delta)	0.045
Flt3	FMS-like tyrosine kinase 3	0.044
AF251705	cDNA sequence AF251705	0.044
Fcgr3	Fc receptor, IgG, low affinity III	0.044
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.044
S1pr4	sphingosine-1-phosphate receptor 4	0.044
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.042
Lcn4	lipocalin 4	0.042
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.041
Aif1	allograft inflammatory factor 1	0.040
Rel	reticuloendotheliosis oncogene	0.040
Csf1	colony stimulating factor 1 (macrophage)	0.039
Ccr8	chemokine (C-C motif) receptor 8	0.039	Mouse
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.039
Cd160	CD160 antigen	0.038
Il23a	interleukin 23, alpha subunit p19	0.037
Psmb7	proteasome (prosome, macropain) subunit, beta type 7	0.037
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.037
Wisp2	WNT1 inducible signaling pathway protein 2	0.037
Igk	immunoglobulin kappa chain complex	0.036
Xcl1	chemokine (C motif) ligand 1	0.036
Rag1	recombination activating gene 1	0.036
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.036
Oosp1	oocyte secreted protein 1	0.035
2410004A20Rik	RIKEN cDNA 2410004A20 gene	0.035
Gcet2	germinal center expressed transcript 2	0.035
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.034
Ccl12	chemokine (C-C motif) ligand 12	0.034
Itgae	integrin alpha E, epithelial-associated	0.034
Fcgr1	Fc receptor, IgG, high affinity I	0.033
Card11	caspase recruitment domain family, member 11	0.033
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.032
Psma5	proteasome (prosome, macropain) subunit, alpha type 5	0.032
Hrh2	histamine receptor H2	0.031
Prss2	protease, serine, 2	0.031
Ctsw	cathepsin W	0.031
Tspo2	translocator protein 2	0.031
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.031
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.030
LOC100502924	hypothetical protein LOC100502924	0.030
Lat	linker for activation of T cells	0.030
Mcpt8	mast cell protease 8	0.030
Il17a	interleukin 17A	0.030
Txk	TXK tyrosine kinase	0.029
Psma7	proteasome (prosome, macropain) subunit, alpha type 7	0.028
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.028
Fcna	ficolin A	0.028
Adora2a	adenosine A2a receptor	0.028
Efna1	ephrin A1	0.028
Ptgs2	prostaglandin-endoperoxide synthase 2	0.027
Hmox1	heme oxygenase (decycling) 1	0.027
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.027
Sfpi1	SFFV proviral integration 1	0.027
Gpr33	G protein-coupled receptor 33	0.026
Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	0.026
H2-Ob	histocompatibility 2, O region beta locus	0.026
Krt84	keratin 84	0.026
Tm4sf5	transmembrane 4 superfamily member 5	0.025
Il18r1	interleukin 18 receptor 1	0.025
Il1a	interleukin 1 alpha	0.025
Igj	immunoglobulin joining chain	0.025
Cd2	CD2 antigen	0.025
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.025
Tcstv3	2-cell-stage, variable group, member 3	0.025
Cd3g	CD3 antigen, gamma polypeptide	0.024
Gdf3	growth differentiation factor 3	0.024
Pramel7	preferentially expressed antigen in melanoma like 7	0.024
Tex19.1	testis expressed gene 19.1	0.023
Psmc4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.023
Dmbt1	deleted in malignant brain tumors 1	0.023
Jak3	Janus kinase 3	0.023
Cd274	CD274 antigen	0.023
Fpr2	formyl peptide receptor 2	0.022
Saa4	serum amyloid A 4	0.022
Lag3	lymphocyte-activation gene 3	0.022
Sell	selectin, lymphocyte	0.022
Oprm1	opioid receptor, mu 1	0.022
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.021
Lck	lymphocyte protein tyrosine kinase	0.021
Mmp8	matrix metallopeptidase 8	0.021
Gzma	granzyme A	0.021
Il18	interleukin 18	0.021
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.021
Nod2	nucleotide-binding oligomerization domain containing 2	0.020
Rc3h1	RING CCCH (C3H) domains 1	0.020
Tnfrsf17	tumor necrosis factor receptor superfamily, member 17	0.020
Trem3	triggering receptor expressed on myeloid cells 3	0.020
Msmb	beta-microseminoprotein	0.020
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.020
Sftpd	surfactant associated protein D	0.019
Tubb2c	tubulin, beta 2C	0.019
Ccl22	chemokine (C-C motif) ligand 22	0.019
Reg1	regenerating islet-derived 1	0.019
Irf4	interferon regulatory factor 4	0.019
Dnase1l3	deoxyribonuclease 1-like 3	0.019
Hc	hemolytic complement	0.019	Mouse
Ido1	indoleamine 2,3-dioxygenase 1	0.018
Cd36	CD36 antigen	0.018
Fcrla	Fc receptor-like A	0.018	Mouse
Irf8	interferon regulatory factor 8	0.018
Akr1c6	aldo-keto reductase family 1, member C6	0.018
Il13ra2	interleukin 13 receptor, alpha 2	0.018
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.018
Lepr	leptin receptor	0.017
Il1rl1	interleukin 1 receptor-like 1	0.017
Gpr182	G protein-coupled receptor 182	0.017
Bcl6	B-cell leukemia/lymphoma 6	0.017
Ly6i	lymphocyte antigen 6 complex, locus I	0.017
Cd8b1	CD8 antigen, beta chain 1	0.017
H2-Q10	histocompatibility 2, Q region locus 10	0.017
Ccrl2	chemokine (C-C motif) receptor-like 2	0.017	Mouse
Gimap7	GTPase, IMAP family member 7	0.016
Sh2d1a	SH2 domain protein 1A	0.016
Eomes	eomesodermin homolog (Xenopus laevis)	0.016
Tlr7	toll-like receptor 7	0.016
Slamf6	SLAM family member 6	0.016
F9	coagulation factor IX	0.016
Uts2r	urotensin 2 receptor	0.016
Agxt	alanine-glyoxylate aminotransferase	0.016
Hrh1	histamine receptor H1	0.016
Hcst	hematopoietic cell signal transducer	0.015
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.015
H2-M9	histocompatibility 2, M region locus 9	0.015
Cxcl10	chemokine (C-X-C motif) ligand 10	0.015
Ikbkg	inhibitor of kappaB kinase gamma	0.015
Itgam	integrin alpha M	0.015
Gpr77	G protein-coupled receptor 77	0.015
Unc93b1	unc-93 homolog B1 (C. elegans)	0.015
Ebi3	Epstein-Barr virus induced gene 3	0.015
Il7r	interleukin 7 receptor	0.015
Art2b	ADP-ribosyltransferase 2b	0.015
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.015
Lbr	lamin B receptor	0.015
Tg	thyroglobulin	0.015
Nos1	nitric oxide synthase 1, neuronal	0.015
Reg2	regenerating islet-derived 2	0.015
Esr1	estrogen receptor 1 (alpha)	0.015
Gfi1	growth factor independent 1	0.015
Cd80	CD80 antigen	0.014
Lipc	lipase, hepatic	0.014
Prg2	proteoglycan 2, bone marrow	0.014
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.014
Ly86	lymphocyte antigen 86	0.014
Cxcr6	chemokine (C-X-C motif) receptor 6	0.014	Mouse
Slurp1	secreted Ly6/Plaur domain containing 1	0.014
Ccl17	chemokine (C-C motif) ligand 17	0.014
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.014
Soat2	sterol O-acyltransferase 2	0.014
H2-Eb2	histocompatibility 2, class II antigen E beta2	0.014
Cst7	cystatin F (leukocystatin)	0.014
Fndc7	fibronectin type III domain containing 7	0.014
Ltf	lactotransferrin	0.014
Lif	leukemia inhibitory factor	0.014
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.014
Cd5l	CD5 antigen-like	0.013
Casp8	caspase 8	0.013
2210415F13Rik	RIKEN cDNA 2210415F13 gene	0.013
Tle6	transducin-like enhancer of split 6, homolog of Drosophila E(spl)	0.013
Dsg4	desmoglein 4	0.013
Reg3g	regenerating islet-derived 3 gamma	0.013
Irg1	immunoresponsive gene 1	0.013
Pla2g2d	phospholipase A2, group IID	0.013
Aqp9	aquaporin 9	0.013
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.013
Cd72	CD72 antigen	0.013
Gpx1	glutathione peroxidase 1	0.013
Klkb1	kallikrein B, plasma 1	0.013
Prg3	proteoglycan 3	0.012
2210010C04Rik	RIKEN cDNA 2210010C04 gene	0.012
Slpi	secretory leukocyte peptidase inhibitor	0.012
Zp3	zona pellucida glycoprotein 3	0.012
Cybb	cytochrome b-245, beta polypeptide	0.012
Gba	glucosidase, beta, acid	0.012
Gsdma3	gasdermin A3	0.012
Bcl3	B-cell leukemia/lymphoma 3	0.012
Il12a	interleukin 12a	0.012
Tnfaip8l2	tumor necrosis factor, alpha-induced protein 8-like 2	0.012
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.012
Fbxo47	F-box protein 47	0.012
Slamf1	signaling lymphocytic activation molecule family member 1	0.012
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.012
Cyp2c44	cytochrome P450, family 2, subfamily c, polypeptide 44	0.012
Spn	sialophorin	0.012
Plg	plasminogen	0.012
Cuzd1	CUB and zona pellucida-like domains 1	0.012
Cox8c	cytochrome c oxidase, subunit VIIIc	0.012
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.012
Ikzf3	IKAROS family zinc finger 3	0.012
Expi	extracellular proteinase inhibitor	0.012
C5ar1	complement component 5a receptor 1	0.012
Traf1	TNF receptor-associated factor 1	0.012
Clnk	cytokine-dependent hematopoietic cell linker	0.012
Ighg	Immunoglobulin heavy chain (gamma polypeptide)	0.011
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.011
Gast	gastrin	0.011
Hck	hemopoietic cell kinase	0.011
Psmb6	proteasome (prosome, macropain) subunit, beta type 6	0.011
Inhbe	inhibin beta E	0.011
Ctss	cathepsin S	0.011
Fgf7	fibroblast growth factor 7	0.011
LOC100503923	hypothetical protein LOC100503923	0.011
Cx3cr1	chemokine (C-X3-C) receptor 1	0.011	Mouse
Stat6	signal transducer and activator of transcription 6	0.011
Aifm1	apoptosis-inducing factor, mitochondrion-associated 1	0.011
AW112010	expressed sequence AW112010	0.011
Serpinb1a	serine (or cysteine) peptidase inhibitor, clade B, member 1a	0.011
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.011
Cma1	chymase 1, mast cell	0.011
Apoh	apolipoprotein H	0.011
Itgax	integrin alpha X	0.011
Slfn3	schlafen 3	0.011
Cfh	complement component factor h	0.011
Psmb5	proteasome (prosome, macropain) subunit, beta type 5	0.011
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.011
Klrb1a	killer cell lectin-like receptor subfamily B member 1A	0.011
Msc	musculin	0.011
Birc3	baculoviral IAP repeat-containing 3	0.011
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.011
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.010
Psmb1	proteasome (prosome, macropain) subunit, beta type 1	0.010
Sytl3	synaptotagmin-like 3	0.010
C2	complement component 2 (within H-2S)	0.010
Fpr3	formyl peptide receptor 3	0.010
Niacr1	niacin receptor 1	0.010
Ctrb1	chymotrypsinogen B1	0.010
Krtap8-1	keratin associated protein 8-1	0.010
St6galnac1	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	0.010
Pou2f2	POU domain, class 2, transcription factor 2	0.010