Mus musculus

314 known processes

Lhx1

LIM homeobox protein 1

(Aliases: Lim1)

Lhx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mesonephric tubule development GO:0072164 94 1.000
nephron epithelium morphogenesis GO:0072088 68 1.000
regionalization GO:0003002 337 1.000
ureteric bud development GO:0001657 94 1.000
retinal ganglion cell axon guidance GO:0031290 18 1.000
Mouse
mesonephric tubule morphogenesis GO:0072171 63 1.000
nephron morphogenesis GO:0072028 69 1.000
kidney epithelium development GO:0072073 121 1.000
renal tubule development GO:0061326 87 1.000
ureteric bud morphogenesis GO:0060675 62 1.000
kidney development GO:0001822 213 1.000
nephron tubule development GO:0072080 84 1.000
nephron tubule morphogenesis GO:0072078 68 0.999
neural tube closure GO:0001843 90 0.999
Mouse
urogenital system development GO:0001655 261 0.999
mesonephric duct morphogenesis GO:0072180 4 0.999
nephron development GO:0072006 109 0.999
paraxial mesodermal cell differentiation GO:0048342 2 0.999
paraxial mesodermal cell fate commitment GO:0048343 2 0.999
renal system development GO:0072001 225 0.999
primary neural tube formation GO:0014020 95 0.999
Mouse
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.999
digestive tract morphogenesis GO:0048546 147 0.999
endoderm development GO:0007492 45 0.999
mesenchyme morphogenesis GO:0072132 32 0.999
Mouse
metanephric tubule development GO:0072170 18 0.999
cell differentiation in hindbrain GO:0021533 24 0.998
forebrain regionalization GO:0021871 25 0.998
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.998
metanephros morphogenesis GO:0003338 24 0.998
motor neuron migration GO:0097475 4 0.998
pituitary gland development GO:0021983 38 0.998
Mouse
olfactory lobe development GO:0021988 32 0.998
Mouse
renal vesicle development GO:0072087 17 0.998
branching involved in ureteric bud morphogenesis GO:0001658 56 0.998
kidney morphogenesis GO:0060993 83 0.998
midbrain hindbrain boundary development GO:0030917 9 0.998
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.998
nephron epithelium development GO:0072009 92 0.998
positive regulation of nephron tubule epithelial cell differentiation GO:2000768 1 0.998
lateral motor column neuron migration GO:0097477 3 0.998
cerebellum formation GO:0021588 1 0.998
sensory organ morphogenesis GO:0090596 242 0.998
embryonic skeletal system morphogenesis GO:0048704 91 0.998
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.997
negative regulation of prostatic bud formation GO:0060686 4 0.997
digestive tract development GO:0048565 190 0.997
morphogenesis of a branching structure GO:0001763 203 0.997
lung induction GO:0060492 3 0.997
cell proliferation in forebrain GO:0021846 30 0.997
Mouse
metanephric renal vesicle morphogenesis GO:0072283 12 0.997
skeletal system morphogenesis GO:0048705 203 0.996
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.996
mesonephric epithelium development GO:0072163 94 0.996
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.996
brain segmentation GO:0035284 3 0.996
metanephric epithelium development GO:0072207 21 0.996
hindbrain formation GO:0021576 1 0.996
neural tube development GO:0021915 160 0.996
Mouse
forebrain development GO:0030900 302 0.996
spemann organizer formation GO:0060061 2 0.995
morphogenesis of embryonic epithelium GO:0016331 159 0.995
Mouse
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.995
mesendoderm development GO:0048382 3 0.995
nephric duct morphogenesis GO:0072178 7 0.995
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.995
hypophysis morphogenesis GO:0048850 3 0.995
spinal cord association neuron differentiation GO:0021527 14 0.995
mesonephric tubule formation GO:0072172 11 0.995
metanephric loop of henle development GO:0072236 4 0.995
epithelial cell differentiation involved in kidney development GO:0035850 23 0.995
appendage morphogenesis GO:0035107 149 0.995
Mouse Fly
metanephric nephron development GO:0072210 34 0.994
epithelial tube formation GO:0072175 130 0.994
Mouse
embryonic organ morphogenesis GO:0048562 276 0.994
stem cell development GO:0048864 219 0.994
Mouse
neuron fate specification GO:0048665 30 0.994
Mouse
positive regulation of interleukin 8 secretion GO:2000484 1 0.993
midbrain hindbrain boundary maturation GO:0021732 1 0.993
regulation of neuron projection development GO:0010975 169 0.993
muscle tissue morphogenesis GO:0060415 53 0.993
Mouse
cerebellar cortex morphogenesis GO:0021696 32 0.993
cardiac septum development GO:0003279 59 0.993
Mouse
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.992
nephron tubule formation GO:0072079 20 0.992
olfactory bulb development GO:0021772 30 0.992
Mouse
mesenchyme development GO:0060485 152 0.992
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.992
Mouse
peripheral nervous system neuron axonogenesis GO:0048936 3 0.992
Mouse
spinal cord motor neuron cell fate specification GO:0021520 13 0.992
Mouse
limb development GO:0060173 166 0.992
Mouse
metanephric dct cell differentiation GO:0072240 3 0.992
oviduct development GO:0060066 3 0.992
mesonephros development GO:0001823 97 0.992
embryonic epithelial tube formation GO:0001838 130 0.991
Mouse
mesonephric duct formation GO:0072181 2 0.991
axis elongation involved in somitogenesis GO:0090245 4 0.991
maintenance of cell number GO:0098727 3 0.991
bmp signaling pathway GO:0030509 93 0.991
primitive streak formation GO:0090009 10 0.991
metanephric nephron morphogenesis GO:0072273 19 0.991
metanephric collecting duct development GO:0072205 7 0.991
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.991
metanephros development GO:0001656 79 0.990
mesenchymal cell development GO:0014031 93 0.990
Mouse
regulation of kidney development GO:0090183 40 0.990
digestive system development GO:0055123 200 0.990
kidney rudiment formation GO:0072003 3 0.990
telencephalon development GO:0021537 186 0.990
hindbrain morphogenesis GO:0021575 46 0.989
mesenchymal cell differentiation GO:0048762 107 0.989
Mouse
gastrulation GO:0007369 116 0.989
metanephric nephron tubule development GO:0072234 16 0.989
metanephric nephron epithelium development GO:0072243 19 0.989
dopaminergic neuron differentiation GO:0071542 14 0.989
Mouse
somitogenesis GO:0001756 69 0.988
forelimb morphogenesis GO:0035136 40 0.988
limb morphogenesis GO:0035108 149 0.988
Mouse
hindbrain development GO:0030902 128 0.987
rostrocaudal neural tube patterning GO:0021903 12 0.986
cerebellar cortex formation GO:0021697 22 0.986
regulation of neuron differentiation GO:0045664 281 0.986
Mouse
cerebellum morphogenesis GO:0021587 42 0.986
forebrain generation of neurons GO:0021872 63 0.986
Mouse
neural tube formation GO:0001841 108 0.986
Mouse
cerebellar granule cell precursor proliferation GO:0021930 10 0.986
negative regulation of neuron differentiation GO:0045665 101 0.985
Mouse
spinal cord motor neuron migration GO:0097476 4 0.985
renal tubule morphogenesis GO:0061333 72 0.985
pattern specification involved in metanephros development GO:0072268 4 0.984
central nervous system segmentation GO:0035283 3 0.984
neural tube patterning GO:0021532 43 0.984
regulation of axon diameter GO:0031133 6 0.984
limbic system development GO:0021761 72 0.983
Mouse
cell proliferation in hindbrain GO:0021534 10 0.983
visceral motor neuron differentiation GO:0021524 3 0.982
Mouse
regulation of organ formation GO:0003156 34 0.982
Mouse
neuron projection guidance GO:0097485 141 0.982
paraxial mesoderm morphogenesis GO:0048340 10 0.981
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.981
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.981
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.981
somatotropin secreting cell differentiation GO:0060126 4 0.980
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.979
forebrain neuron development GO:0021884 30 0.979
Mouse
nephric duct formation GO:0072179 4 0.979
cardiac right atrium morphogenesis GO:0003213 3 0.978
cerebellum development GO:0021549 77 0.978
morphogenesis of a branching epithelium GO:0061138 193 0.978
cell differentiation in spinal cord GO:0021515 53 0.978
nephron tubule epithelial cell differentiation GO:0072160 11 0.976
endocrine system development GO:0035270 98 0.976
Mouse
neuron projection extension GO:1990138 64 0.976
Mouse
forebrain neuron differentiation GO:0021879 52 0.975
Mouse
sensory system development GO:0048880 3 0.975
Mouse
organ induction GO:0001759 21 0.975
axonogenesis GO:0007409 274 0.973
hippocampus development GO:0021766 52 0.972
Mouse
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.972
chemotaxis GO:0006935 247 0.972
regulation of organ morphogenesis GO:2000027 144 0.972
renal vesicle morphogenesis GO:0072077 15 0.971
regulation of bmp signaling pathway GO:0030510 60 0.971
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.970
forebrain morphogenesis GO:0048853 17 0.970
embryonic appendage morphogenesis GO:0035113 126 0.970
stem cell differentiation GO:0048863 268 0.970
Mouse
cerebral cortex radially oriented cell migration GO:0021799 31 0.969
Mouse
metanephric s shaped body morphogenesis GO:0072284 2 0.968
central nervous system neuron differentiation GO:0021953 162 0.968
negative regulation of axon extension GO:0030517 19 0.967
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.967
central nervous system morphogenesis GO:0021551 2 0.966
cardiac muscle cell differentiation GO:0055007 69 0.966
negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 4 0.965
mesenchymal stem cell maintenance involved in nephron morphogenesis GO:0072038 7 0.965
cerebellar cortex development GO:0021695 48 0.964
pallium development GO:0021543 120 0.964
Mouse
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.963
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.962
establishment of organ orientation GO:0048561 1 0.962
cerebellar granule cell differentiation GO:0021707 9 0.962
specification of organ identity GO:0010092 30 0.962
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.961
ventral spinal cord interneuron specification GO:0021521 11 0.961
Mouse
pyramidal neuron migration GO:0021852 1 0.961
renal vesicle induction GO:0072034 3 0.961
olfactory bulb interneuron differentiation GO:0021889 12 0.960
embryonic axis specification GO:0000578 30 0.960
trabecular meshwork development GO:0002930 2 0.959
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.959
cerebellar granular layer development GO:0021681 13 0.958
positive regulation of neuron differentiation GO:0045666 141 0.957
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.957
mesoderm development GO:0007498 100 0.957
Mouse
paramesonephric duct development GO:0061205 3 0.956
regulation of chondrocyte differentiation GO:0032330 33 0.955
renal outer medulla development GO:0072054 2 0.955
mesenchymal to epithelial transition GO:0060231 12 0.955
negative regulation of neuron projection development GO:0010977 50 0.955
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.955
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.954
muscle tissue development GO:0060537 308 0.954
Mouse
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.953
developmental cell growth GO:0048588 84 0.952
Mouse
polarity specification of proximal distal axis GO:0010085 2 0.951
metanephric glomerulus development GO:0072224 13 0.951
Rat
medial motor column neuron differentiation GO:0021526 2 0.949
Mouse
pronephric nephron development GO:0039019 1 0.948
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.947
cervix development GO:0060067 2 0.946
ventricular septum morphogenesis GO:0060412 27 0.945
retina development in camera type eye GO:0060041 119 0.945
negative regulation of androgen biosynthetic process GO:2000180 1 0.943
pattern specification involved in kidney development GO:0061004 8 0.942
stem cell proliferation GO:0072089 117 0.942
regulation of angiogenesis GO:0045765 81 0.942
Mouse
chondrocyte differentiation GO:0002062 72 0.942
tube formation GO:0035148 140 0.941
Mouse
cell fate determination GO:0001709 32 0.941
Mouse
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.940
cerebral cortex development GO:0021987 86 0.940
Mouse
ventral spinal cord interneuron fate commitment GO:0060579 14 0.940
Mouse
embryonic digit morphogenesis GO:0042733 56 0.940
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.939
loop of henle development GO:0072070 10 0.939
embryonic limb morphogenesis GO:0030326 126 0.939
metanephric distal convoluted tubule development GO:0072221 5 0.938
olfactory bulb interneuron development GO:0021891 7 0.938
cerebellar granular layer morphogenesis GO:0021683 10 0.936
branching morphogenesis of an epithelial tube GO:0048754 159 0.936
diencephalon development GO:0021536 63 0.935
Mouse
embryonic heart tube morphogenesis GO:0003143 51 0.933
foregut regionalization GO:0060423 3 0.933
determination of heart left right asymmetry GO:0061371 48 0.933
cardiac cell fate commitment GO:0060911 10 0.933
Mouse
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.932
glomerulus development GO:0032835 40 0.931
Rat
cardiac ventricle morphogenesis GO:0003208 50 0.931
Mouse
bone morphogenesis GO:0060349 78 0.931
inner medullary collecting duct development GO:0072061 2 0.930
mesoderm morphogenesis GO:0048332 64 0.930
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.929
negative regulation of axon guidance GO:1902668 8 0.928
gonad morphogenesis GO:0035262 1 0.928
Mouse
dorsal ventral neural tube patterning GO:0021904 28 0.927
endoderm formation GO:0001706 20 0.927
regulation of asymmetric cell division GO:0009786 4 0.925
forebrain anterior posterior pattern specification GO:0021797 5 0.924
cardiac chamber development GO:0003205 108 0.924
Mouse
epithelial tube morphogenesis GO:0060562 303 0.922
motor neuron axon guidance GO:0008045 26 0.921
uterus morphogenesis GO:0061038 2 0.921
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.920
axon guidance GO:0007411 141 0.920
regulation of neuron apoptotic process GO:0043523 122 0.917
Mouse
positive regulation of anagen GO:0051885 1 0.917
dct cell differentiation GO:0072069 3 0.917
kidney mesenchyme morphogenesis GO:0072131 4 0.917
regulation of metanephros development GO:0072215 15 0.916
atrial cardiac muscle tissue development GO:0003228 5 0.915
neuroendocrine cell differentiation GO:0061101 7 0.914
cardiac muscle tissue morphogenesis GO:0055008 44 0.914
Mouse
positive regulation of mesonephros development GO:0061213 20 0.914
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.912
negative regulation of stem cell maintenance GO:1902455 4 0.912
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.912
cardiac epithelial to mesenchymal transition GO:0060317 18 0.912
auditory receptor cell fate determination GO:0042668 3 0.911
nephric duct development GO:0072176 7 0.910
cell differentiation involved in kidney development GO:0061005 33 0.909
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.907
mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis GO:0072309 3 0.907
tube closure GO:0060606 91 0.906
Mouse
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003339 5 0.906
anterior head development GO:0097065 2 0.906
gonad development GO:0008406 141 0.906
Mouse
eye photoreceptor cell fate commitment GO:0042706 2 0.904
cardiac ventricle development GO:0003231 83 0.904
Mouse
lung morphogenesis GO:0060425 50 0.901
establishment of endothelial blood brain barrier GO:0014045 3 0.899
cardiocyte differentiation GO:0035051 87 0.899
Mouse
embryonic heart tube development GO:0035050 65 0.899
cell fate specification GO:0001708 72 0.899
Mouse Worm
gland development GO:0048732 330 0.898
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.898
fibroblast growth factor production GO:0090269 4 0.896
trachea cartilage morphogenesis GO:0060535 4 0.895
stem cell maintenance GO:0019827 130 0.893
embryonic viscerocranium morphogenesis GO:0048703 8 0.892
midgut development GO:0007494 4 0.891
metanephric tubule morphogenesis GO:0072173 9 0.891
uterus development GO:0060065 16 0.890
regulation of axon extension GO:0030516 43 0.890
endocardial cushion morphogenesis GO:0003203 18 0.890
Mouse
embryonic eye morphogenesis GO:0048048 29 0.889
central nervous system neuron development GO:0021954 67 0.889
Mouse
negative regulation of bmp signaling pathway GO:0030514 35 0.889
formation of primary germ layer GO:0001704 77 0.886
canonical wnt signaling pathway GO:0060070 130 0.886
Mouse
metanephric mesenchymal cell differentiation GO:0072162 3 0.885
diencephalon morphogenesis GO:0048852 6 0.885
odontogenesis of dentin containing tooth GO:0042475 66 0.884
Mouse
positive regulation of heart growth GO:0060421 18 0.883
respiratory system development GO:0060541 190 0.883
spinal cord dorsal ventral patterning GO:0021513 23 0.882
Mouse
renal inner medulla development GO:0072053 3 0.880
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.880
developmental induction GO:0031128 34 0.879
photoreceptor cell fate commitment GO:0046552 2 0.879
regulation of heart growth GO:0060420 31 0.878
metanephric comma shaped body morphogenesis GO:0072278 1 0.877
Rat
embryonic retina morphogenesis in camera type eye GO:0060059 7 0.877
mesodermal cell differentiation GO:0048333 22 0.875
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation GO:0044343 1 0.875
odontogenesis GO:0042476 78 0.874
Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.874
hindlimb morphogenesis GO:0035137 42 0.872
androgen biosynthetic process GO:0006702 4 0.872
lung field specification GO:0060424 3 0.871
regulation of metanephric glomerulus development GO:0072298 5 0.868
striated muscle tissue development GO:0014706 293 0.867
Mouse
brain morphogenesis GO:0048854 32 0.864
anterior posterior axis specification embryo GO:0008595 9 0.863
ear morphogenesis GO:0042471 118 0.863
mesangial cell differentiation GO:0072007 4 0.862
metanephric mesenchyme morphogenesis GO:0072133 4 0.862
epithelial cell morphogenesis GO:0003382 41 0.859
cellular ketone metabolic process GO:0042180 84 0.858
cartilage morphogenesis GO:0060536 11 0.858
cellular amino acid metabolic process GO:0006520 103 0.858
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.856
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.855
renal system pattern specification GO:0072048 9 0.855
neuron fate determination GO:0048664 9 0.855
positive regulation of interleukin 6 production GO:0032755 37 0.854
Mouse
regulation of anagen GO:0051884 1 0.851
adenohypophysis development GO:0021984 14 0.850
positive regulation of interleukin 1 beta production GO:0032731 16 0.850
Mouse
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.850
mesoderm formation GO:0001707 62 0.849
gas homeostasis GO:0033483 3 0.849
gastrulation with mouth forming second GO:0001702 29 0.848
negative regulation of synapse assembly GO:0051964 3 0.848
horizontal cell localization GO:0035852 1 0.847
response to acid chemical GO:0001101 111 0.846
eye photoreceptor cell differentiation GO:0001754 41 0.845
regulation of apoptotic signaling pathway GO:2001233 197 0.843
anterior commissure morphogenesis GO:0021960 6 0.842
mesonephric duct development GO:0072177 5 0.839
Rat
innervation GO:0060384 22 0.839
Mouse
epithalamus development GO:0021538 2 0.835
positive regulation of transcription by glucose GO:0046016 3 0.835
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.833
extracellular matrix organization GO:0030198 147 0.832
Mouse
cardiac muscle tissue development GO:0048738 130 0.831
Mouse
cochlea morphogenesis GO:0090103 22 0.831
response to molecule of bacterial origin GO:0002237 143 0.830
skeletal muscle organ development GO:0060538 163 0.829
response to fibroblast growth factor GO:0071774 47 0.828
Rat
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.825
midbrain development GO:0030901 35 0.824
Mouse
cardiac cell fate determination GO:0060913 2 0.823
Mouse
heart formation GO:0060914 16 0.823
Mouse
cerebellar granular layer formation GO:0021684 9 0.823
mammary gland duct morphogenesis GO:0060603 38 0.821
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.819
outflow tract morphogenesis GO:0003151 53 0.819
Mouse
negative regulation of wnt signaling pathway GO:0030178 73 0.817
Mouse
respiratory tube development GO:0030323 167 0.817
maternal process involved in female pregnancy GO:0060135 32 0.816
positive regulation of cartilage development GO:0061036 18 0.816
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.816
positive regulation of metanephric glomerulus development GO:0072300 4 0.815
central nervous system vasculogenesis GO:0022009 3 0.815
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.810
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.810
heart morphogenesis GO:0003007 178 0.810
Mouse
mammary gland epithelium development GO:0061180 65 0.809
metanephric nephron tubule epithelial cell differentiation GO:0072257 5 0.809
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.809
establishment of anatomical structure orientation GO:0048560 1 0.808
positive regulation of kidney development GO:0090184 28 0.808
cell cell signaling involved in cell fate commitment GO:0045168 35 0.806
positive regulation of nervous system development GO:0051962 221 0.805
glial cell differentiation GO:0010001 131 0.804
organic hydroxy compound metabolic process GO:1901615 203 0.804
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.804
epithelial cell development GO:0002064 159 0.803
regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900211 4 0.803
glomerular epithelial cell differentiation GO:0072311 10 0.802
hypothalamus development GO:0021854 16 0.801
metanephric nephron tubule formation GO:0072289 4 0.801
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.800
oxygen homeostasis GO:0032364 2 0.800
positive regulation of synapse assembly GO:0051965 18 0.799
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.798
trophectodermal cell differentiation GO:0001829 21 0.797
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.796
camera type eye development GO:0043010 266 0.795
cerebellar purkinje cell layer formation GO:0021694 13 0.794
type b pancreatic cell differentiation GO:0003309 13 0.794
determination of left right symmetry GO:0007368 80 0.792
positive regulation of cellular amine metabolic process GO:0033240 5 0.791
tendon formation GO:0035992 4 0.787
negative regulation of kidney development GO:0090185 15 0.787
cell fate commitment GO:0045165 210 0.783
Mouse Worm
regulation of glomerulus development GO:0090192 6 0.783
cardiac septum morphogenesis GO:0060411 46 0.782
Mouse
collecting duct development GO:0072044 11 0.779
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.779
Mouse
forebrain neuron fate commitment GO:0021877 13 0.779
Mouse
cardiac muscle cell proliferation GO:0060038 31 0.778
tripartite regional subdivision GO:0007351 9 0.775
smoothened signaling pathway GO:0007224 105 0.774
positive regulation of cardiac muscle tissue development GO:0055025 19 0.773
positive regulation of cerebellar granule cell precursor proliferation GO:0021940 10 0.771
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.771
endodermal cell fate commitment GO:0001711 12 0.769
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.766
cerebellar purkinje cell layer development GO:0021680 26 0.765
skeletal muscle cell differentiation GO:0035914 66 0.765
regulation of testosterone biosynthetic process GO:2000224 2 0.763
rhombomere morphogenesis GO:0021593 2 0.762
outer medullary collecting duct development GO:0072060 1 0.760
tendon cell differentiation GO:0035990 4 0.760
connective tissue development GO:0061448 179 0.757
cardiac atrium morphogenesis GO:0003209 23 0.757
Mouse
wnt signaling pathway GO:0016055 188 0.756
Mouse
extracellular structure organization GO:0043062 148 0.755
Mouse
regulation of interleukin 1 alpha production GO:0032650 4 0.752
Mouse
synaptic transmission GO:0007268 329 0.752
endochondral bone morphogenesis GO:0060350 50 0.749
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.748
positive regulation of jun kinase activity GO:0043507 30 0.745
positive regulation of rhodopsin gene expression GO:0045872 2 0.742
enteroendocrine cell differentiation GO:0035883 16 0.741
neural retina development GO:0003407 41 0.737
ventral spinal cord interneuron differentiation GO:0021514 16 0.737
Mouse
ensheathment of neurons GO:0007272 76 0.735
renal capsule specification GO:0072130 1 0.734
somite rostral caudal axis specification GO:0032525 13 0.727
cellular response to molecule of bacterial origin GO:0071219 83 0.726
specification of nephron tubule identity GO:0072081 5 0.724
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.724
striated muscle cell proliferation GO:0014855 39 0.722
nerve development GO:0021675 67 0.721
Mouse
ectoderm formation GO:0001705 3 0.721
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.721
cell type specific apoptotic process GO:0097285 268 0.720
Mouse
development of primary male sexual characteristics GO:0046546 88 0.719
Mouse
cellular response to parathyroid hormone stimulus GO:0071374 2 0.717
prostatic bud formation GO:0060513 10 0.716
pharyngeal system development GO:0060037 17 0.715
Mouse
endomembrane system organization GO:0010256 147 0.714
sclerotome development GO:0061056 4 0.714
vagina development GO:0060068 11 0.713
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.712
apoptotic process involved in patterning of blood vessels GO:1902262 6 0.709
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.709
labyrinthine layer blood vessel development GO:0060716 21 0.707
regulation of epithelial cell proliferation GO:0050678 141 0.706
neurohypophysis development GO:0021985 2 0.704
morphogenesis of an epithelial fold GO:0060571 28 0.704
male sex differentiation GO:0046661 109 0.704
Mouse
optic nerve structural organization GO:0021633 2 0.703
cranial nerve development GO:0021545 41 0.703
Mouse
negative regulation of molecular function GO:0044092 258 0.697
Mouse
somatic stem cell maintenance GO:0035019 47 0.697
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.697
regulation of mesonephros development GO:0061217 24 0.695
regulation of stem cell proliferation GO:0072091 78 0.693
sensory perception GO:0007600 245 0.689
positive regulation of protein modification process GO:0031401 299 0.688
Mouse
cerebral cortex radial glia guided migration GO:0021801 17 0.686
cop9 signalosome assembly GO:0010387 2 0.686
embryonic skeletal joint morphogenesis GO:0060272 11 0.686
mesodermal cell fate commitment GO:0001710 17 0.685
regulation of mesenchymal cell proliferation GO:0010464 37 0.680
interleukin 8 production GO:0032637 4 0.677
regulation of morphogenesis of a branching structure GO:0060688 53 0.676
cellular response to biotic stimulus GO:0071216 92 0.675
positive regulation of bone mineralization GO:0030501 12 0.673
positive regulation of protein phosphorylation GO:0001934 242 0.672
Mouse
regulation of interleukin 1 production GO:0032652 26 0.671
Mouse
trigeminal nerve development GO:0021559 10 0.668
Mouse
granulocyte colony stimulating factor production GO:0071611 1 0.666
Mouse
pericardium development GO:0060039 16 0.666
negative regulation of hormone metabolic process GO:0032351 4 0.666
embryonic camera type eye development GO:0031076 36 0.665
embryonic hindlimb morphogenesis GO:0035116 32 0.665
epithelial to mesenchymal transition GO:0001837 47 0.665
type b pancreatic cell proliferation GO:0044342 10 0.665
cerebellar purkinje cell granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation GO:0021937 6 0.665
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.663
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.661

Lhx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
kidney disease DOID:557 0 0.869
disease of anatomical entity DOID:7 0 0.869
urinary system disease DOID:18 0 0.869