IMP

Process View

Mus musculus

1 genes annotated in mouse

positive regulation of nephron tubule epithelial cell differentiation

GO:2000768

Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of nephron tubule epithelial cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of nephron tubule epithelial cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Otx2	orthodenticle homolog 2 (Drosophila)	1.000
Pax6	paired box gene 6	1.000
Pax2	paired box gene 2	1.000
Emx2	empty spiracles homolog 2 (Drosophila)	1.000
Pitx2	paired-like homeodomain transcription factor 2	1.000
Emx1	empty spiracles homolog 1 (Drosophila)	0.999
Shh	sonic hedgehog	0.999
Lhx1	LIM homeobox protein 1	0.998
Lhx3	LIM homeobox protein 3	0.996	Mouse
Fgf8	fibroblast growth factor 8	0.991
Gbx2	gastrulation brain homeobox 2	0.980
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.972
Lhx9	LIM homeobox protein 9	0.920	Mouse
Otx1	orthodenticle homolog 1 (Drosophila)	0.911
Pou4f2	POU domain, class 4, transcription factor 2	0.889
Hes5	hairy and enhancer of split 5 (Drosophila)	0.880
Pax3	paired box gene 3	0.879
Sox2	SRY-box containing gene 2	0.795
Gli3	GLI-Kruppel family member GLI3	0.783
Wt1	Wilms tumor 1 homolog	0.730
Lhx4	LIM homeobox protein 4	0.665	Mouse
Tcfap2a	transcription factor AP-2, alpha	0.664
En1	engrailed 1	0.654
Neurod1	neurogenic differentiation 1	0.606
Sox11	SRY-box containing gene 11	0.588
Hoxa1	homeobox A1	0.514
Kiss1r	KISS1 receptor	0.513
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.501
Foxc1	forkhead box C1	0.487
Insm1	insulinoma-associated 1	0.434
Phox2b	paired-like homeobox 2b	0.418
Neurog2	neurogenin 2	0.407
Nodal	nodal	0.403
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.371
Chd7	chromodomain helicase DNA binding protein 7	0.341
Lmx1b	LIM homeobox transcription factor 1 beta	0.314	Mouse
Eya1	eyes absent 1 homolog (Drosophila)	0.293
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.285
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.272
Zic3	zinc finger protein of the cerebellum 3	0.260
Tbx1	T-box 1	0.254
Atoh7	atonal homolog 7 (Drosophila)	0.252
Lhx5	LIM homeobox protein 5	0.246	Mouse
Foxg1	forkhead box G1	0.242
Hmx3	H6 homeobox 3	0.232
Wnt9b	wingless-type MMTV integration site 9B	0.216
Pax7	paired box gene 7	0.216
Isl1	ISL1 transcription factor, LIM/homeodomain	0.211	Mouse
Hand2	heart and neural crest derivatives expressed transcript 2	0.204
En2	engrailed 2	0.184
Gata4	GATA binding protein 4	0.175
Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.168
BC024139	cDNA sequence BC024139	0.167
Nog	noggin	0.157
Sox3	SRY-box containing gene 3	0.149
Vgf	VGF nerve growth factor inducible	0.136
Pax8	paired box gene 8	0.132
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.122
Foxc2	forkhead box C2	0.108
Hand1	heart and neural crest derivatives expressed transcript 1	0.107
Ret	ret proto-oncogene	0.107
Kiss1	KiSS-1 metastasis-suppressor	0.103
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.100
Emid2	EMI domain containing 2	0.098
Fgf3	fibroblast growth factor 3	0.093
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.088
Onecut1	one cut domain, family member 1	0.086
Isl2	insulin related protein 2 (islet 2)	0.081	Mouse
Lmx1a	LIM homeobox transcription factor 1 alpha	0.079	Mouse
Arx	aristaless related homeobox	0.077
Mab21l2	mab-21-like 2 (C. elegans)	0.073
Drd2	dopamine receptor D2	0.069
Ptf1a	pancreas specific transcription factor, 1a	0.069
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.055
Uncx	UNC homeobox	0.054
Pou4f3	POU domain, class 4, transcription factor 3	0.053
Foxe3	forkhead box E3	0.052
Olig2	oligodendrocyte transcription factor 2	0.051
Dlx1	distal-less homeobox 1	0.050
Zic2	zinc finger protein of the cerebellum 2	0.050
Sall3	sal-like 3 (Drosophila)	0.048
Hoxd13	homeobox D13	0.046
Rarb	retinoic acid receptor, beta	0.045
Esr1	estrogen receptor 1 (alpha)	0.043
Pou3f4	POU domain, class 3, transcription factor 4	0.043
Sim1	single-minded homolog 1 (Drosophila)	0.041
Slc6a1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.041
Sox9	SRY-box containing gene 9	0.040
Gdnf	glial cell line derived neurotrophic factor	0.040
Osr1	odd-skipped related 1 (Drosophila)	0.039
Cacng4	calcium channel, voltage-dependent, gamma subunit 4	0.039
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.039
Cer1	cerberus 1 homolog (Xenopus laevis)	0.038
Foxh1	forkhead box H1	0.037
Prop1	paired like homeodomain factor 1	0.035
Tcfap2c	transcription factor AP-2, gamma	0.035
Cntn2	contactin 2	0.035
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.034
Nkx6-1	NK6 homeobox 1	0.032
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.032
Dmbx1	diencephalon/mesencephalon homeobox 1	0.032
Vsx2	visual system homeobox 2	0.031
Fgf10	fibroblast growth factor 10	0.031
Smo	smoothened homolog (Drosophila)	0.031
Neurod4	neurogenic differentiation 4	0.031
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.029
Igfbpl1	insulin-like growth factor binding protein-like 1	0.029
Sez6l	seizure related 6 homolog like	0.029
Pou3f2	POU domain, class 3, transcription factor 2	0.029
Pitx1	paired-like homeodomain transcription factor 1	0.028
Barhl2	BarH-like 2 (Drosophila)	0.028
Prokr2	prokineticin receptor 2	0.028
Fgfr2	fibroblast growth factor receptor 2	0.028
Hoxa11	homeobox A11	0.028
T	brachyury	0.027
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.027
Nhlh1	nescient helix loop helix 1	0.026
Msx2	homeobox, msh-like 2	0.026
Srrm4	serine/arginine repetitive matrix 4	0.025
Hoxd11	homeobox D11	0.025
Glra1	glycine receptor, alpha 1 subunit	0.025
Foxi1	forkhead box I1	0.025
Foxl2	forkhead box L2	0.025
Cga	glycoprotein hormones, alpha subunit	0.024
Zic1	zinc finger protein of the cerebellum 1	0.023
Il11	interleukin 11	0.023
Tnnc2	troponin C2, fast	0.022
Pou3f1	POU domain, class 3, transcription factor 1	0.022
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.022
Dlx5	distal-less homeobox 5	0.022
Ncan	neurocan	0.022
Lhx6	LIM homeobox protein 6	0.021	Mouse
Magel2	melanoma antigen, family L, 2	0.021
Fgf22	fibroblast growth factor 22	0.021
Sorcs3	sortilin-related VPS10 domain containing receptor 3	0.020
Hoxd3	homeobox D3	0.020
Fzd10	frizzled homolog 10 (Drosophila)	0.020
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.020
Cbln1	cerebellin 1 precursor protein	0.020
Vgll2	vestigial like 2 homolog (Drosophila)	0.019
Wnt1	wingless-related MMTV integration site 1	0.019
Nhlh2	nescient helix loop helix 2	0.019
Cdh8	cadherin 8	0.019
2610109H07Rik	RIKEN cDNA 2610109H07 gene	0.019
Sall4	sal-like 4 (Drosophila)	0.019
Sox21	SRY-box containing gene 21	0.019
Dcc	deleted in colorectal carcinoma	0.018
Syt2	synaptotagmin II	0.018
Scrt2	scratch homolog 2, zinc finger protein (Drosophila)	0.018
Tlx3	T-cell leukemia, homeobox 3	0.017
Sox10	SRY-box containing gene 10	0.017
Ribc2	RIB43A domain with coiled-coils 2	0.016
1700106J16Rik	RIKEN cDNA 1700106J16 gene	0.016
Ina	internexin neuronal intermediate filament protein, alpha	0.016
Evx1	even skipped homeotic gene 1 homolog	0.016
Hmx2	H6 homeobox 2	0.016
Foxn4	forkhead box N4	0.016
Scrt1	scratch homolog 1, zinc finger protein (Drosophila)	0.016
Col22a1	collagen, type XXII, alpha 1	0.016
Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	0.016
Dscaml1	Down syndrome cell adhesion molecule-like 1	0.015
Cldn11	claudin 11	0.015
Hoxa4	homeobox A4	0.015
Cntnap2	contactin associated protein-like 2	0.015
Msx1	homeobox, msh-like 1	0.015
Tcerg1l	transcription elongation regulator 1-like	0.015
Dll3	delta-like 3 (Drosophila)	0.015
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.015
Vangl2	vang-like 2 (van gogh, Drosophila)	0.015
Hmx1	H6 homeobox 1	0.014
Vstm2b	V-set and transmembrane domain containing 2B	0.014
Fgf15	fibroblast growth factor 15	0.014
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.014
Bdnf	brain derived neurotrophic factor	0.014
Dusp9	dual specificity phosphatase 9	0.014
Trpm1	transient receptor potential cation channel, subfamily M, member 1	0.014
Chrna4	cholinergic receptor, nicotinic, alpha polypeptide 4	0.014
Fshr	follicle stimulating hormone receptor	0.014
Oprd1	opioid receptor, delta 1	0.014
Dlx6	distal-less homeobox 6	0.013
Gpr45	G protein-coupled receptor 45	0.013
Olfr70	olfactory receptor 70	0.013
Barhl1	BarH-like 1 (Drosophila)	0.013
Grm2	glutamate receptor, metabotropic 2	0.013
Msx3	homeobox, msh-like 3	0.013
Dmrt3	doublesex and mab-3 related transcription factor 3	0.013
Pygo1	pygopus 1	0.013
Neurog1	neurogenin 1	0.013
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.013
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.013
Gad2	glutamic acid decarboxylase 2	0.013
Fev	FEV (ETS oncogene family)	0.013
Irs4	insulin receptor substrate 4	0.013
Gh	growth hormone	0.013
Odz2	odd Oz/ten-m homolog 2 (Drosophila)	0.013
Crtac1	cartilage acidic protein 1	0.013
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.013
Dcx	doublecortin	0.013
Lef1	lymphoid enhancer binding factor 1	0.013
Cldn14	claudin 14	0.012
Onecut2	one cut domain, family member 2	0.012
Adcyap1	adenylate cyclase activating polypeptide 1	0.012
Foxb1	forkhead box B1	0.012
Nobox	NOBOX oogenesis homeobox	0.012
Bhlhe22	basic helix-loop-helix family, member e22	0.012
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.012
Matn3	matrilin 3	0.012
Tacr3	tachykinin receptor 3	0.012
Ebf3	early B-cell factor 3	0.012
Tll2	tolloid-like 2	0.012
Ecel1	endothelin converting enzyme-like 1	0.012
Col25a1	collagen, type XXV, alpha 1	0.012
Irs2	insulin receptor substrate 2	0.011
Gsx2	GS homeobox 2	0.011
Rtbdn	retbindin	0.011
Megf11	multiple EGF-like-domains 11	0.011
Dpf1	D4, zinc and double PHD fingers family 1	0.011
Crabp2	cellular retinoic acid binding protein II	0.011
Neurod2	neurogenic differentiation 2	0.011
Bmp4	bone morphogenetic protein 4	0.011
4922505E12Rik	RIKEN cDNA 4922505E12 gene	0.011
L1td1	LINE-1 type transposase domain containing 1	0.011
Col2a1	collagen, type II, alpha 1	0.011
St8sia3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	0.011
Myt1	myelin transcription factor 1	0.011
Pou3f3	POU domain, class 3, transcription factor 3	0.011
Btn1a1	butyrophilin, subfamily 1, member A1	0.011
Fgf4	fibroblast growth factor 4	0.011
Fgf17	fibroblast growth factor 17	0.010
Shisa9	shisa homolog 9 (Xenopus laevis)	0.010
Ptprt	protein tyrosine phosphatase, receptor type, T	0.010
Lect2	leukocyte cell-derived chemotaxin 2	0.010