IMP

Process View

Mus musculus

11 genes annotated in mouse

nephron tubule epithelial cell differentiation

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nephron tubule epithelial cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "nephron tubule epithelial cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Emx2	empty spiracles homolog 2 (Drosophila)	0.995
Pax2	paired box gene 2	0.993
Gata4	GATA binding protein 4	0.991	Mouse
Shh	sonic hedgehog	0.989
Pitx2	paired-like homeodomain transcription factor 2	0.988
Pax3	paired box gene 3	0.976
Lhx1	LIM homeobox protein 1	0.976
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.963
Otx2	orthodenticle homolog 2 (Drosophila)	0.942
Fgfr2	fibroblast growth factor receptor 2	0.934
Lhx9	LIM homeobox protein 9	0.894	Mouse
Wt1	Wilms tumor 1 homolog	0.893
Gli3	GLI-Kruppel family member GLI3	0.877
Rarg	retinoic acid receptor, gamma	0.788
Foxc1	forkhead box C1	0.747
Tbx1	T-box 1	0.730
Fgf8	fibroblast growth factor 8	0.724
Emx1	empty spiracles homolog 1 (Drosophila)	0.702
Lhx3	LIM homeobox protein 3	0.691	Mouse
Tbx3	T-box 3	0.637
Gata6	GATA binding protein 6	0.618	Mouse
Rxra	retinoid X receptor alpha	0.618
Hand1	heart and neural crest derivatives expressed transcript 1	0.602
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.579
Vegfa	vascular endothelial growth factor A	0.561
Bmp4	bone morphogenetic protein 4	0.505
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.483
Otx1	orthodenticle homolog 1 (Drosophila)	0.442
Jag1	jagged 1	0.428
Hoxa1	homeobox A1	0.419
Pax6	paired box gene 6	0.393
Wnt9b	wingless-type MMTV integration site 9B	0.360
Lef1	lymphoid enhancer binding factor 1	0.348
Ctnnb1	catenin (cadherin associated protein), beta 1	0.342
Foxc2	forkhead box C2	0.340
Eya1	eyes absent 1 homolog (Drosophila)	0.292
Hdac4	histone deacetylase 4	0.291
Rara	retinoic acid receptor, alpha	0.270
Gbx2	gastrulation brain homeobox 2	0.269
Rarb	retinoic acid receptor, beta	0.259
Hand2	heart and neural crest derivatives expressed transcript 2	0.256
Hoxa11	homeobox A11	0.252
Sox2	SRY-box containing gene 2	0.248
Pax8	paired box gene 8	0.242
Yap1	yes-associated protein 1	0.227
Gdnf	glial cell line derived neurotrophic factor	0.224
Wwtr1	WW domain containing transcription regulator 1	0.220
Msx1	homeobox, msh-like 1	0.216
Fgf10	fibroblast growth factor 10	0.199
Chd7	chromodomain helicase DNA binding protein 7	0.186
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.162
Bnc1	basonuclin 1	0.132
Foxf1a	forkhead box F1a	0.126
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.123
Pou4f2	POU domain, class 4, transcription factor 2	0.118
Fgfr1	fibroblast growth factor receptor 1	0.117
Pou4f3	POU domain, class 4, transcription factor 3	0.114
Hdac7	histone deacetylase 7	0.114
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.096
Isl1	ISL1 transcription factor, LIM/homeodomain	0.094	Mouse
Tead1	TEA domain family member 1	0.094
Efnb2	ephrin B2	0.088
Hes5	hairy and enhancer of split 5 (Drosophila)	0.087
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.084
Trp63	transformation related protein 63	0.083
Wnt3a	wingless-related MMTV integration site 3A	0.081
Qk	quaking	0.080
Tead3	TEA domain family member 3	0.073
Smad6	MAD homolog 6 (Drosophila)	0.072
Hoxd11	homeobox D11	0.072
Tal1	T-cell acute lymphocytic leukemia 1	0.070
Bcl2	B-cell leukemia/lymphoma 2	0.069
Sox11	SRY-box containing gene 11	0.069
Lmx1a	LIM homeobox transcription factor 1 alpha	0.065	Mouse
Pitx1	paired-like homeodomain transcription factor 1	0.065
Tgfb2	transforming growth factor, beta 2	0.063
Runx1	runt related transcription factor 1	0.062
Zfpm2	zinc finger protein, multitype 2	0.060
Foxg1	forkhead box G1	0.058
Sox7	SRY-box containing gene 7	0.056
Tbx20	T-box 20	0.053
Sox4	SRY-box containing gene 4	0.053
Pten	phosphatase and tensin homolog	0.052
Lhx4	LIM homeobox protein 4	0.052	Mouse
Twist2	twist homolog 2 (Drosophila)	0.052
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.052
T	brachyury	0.050
Wnt4	wingless-related MMTV integration site 4	0.050
Fgf3	fibroblast growth factor 3	0.050
Osr1	odd-skipped related 1 (Drosophila)	0.048
Nodal	nodal	0.048
Hoxd13	homeobox D13	0.045
Ednra	endothelin receptor type A	0.045
Hoxb3	homeobox B3	0.044
Lamc1	laminin, gamma 1	0.044
Hoxa4	homeobox A4	0.044
Sox9	SRY-box containing gene 9	0.043
Prop1	paired like homeodomain factor 1	0.043
Klf3	Kruppel-like factor 3 (basic)	0.042
Tcfap2a	transcription factor AP-2, alpha	0.041
Hoxa3	homeobox A3	0.040
Hdac5	histone deacetylase 5	0.038
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.038
Gja5	gap junction protein, alpha 5	0.037
Nfib	nuclear factor I/B	0.036
Notch1	Notch gene homolog 1 (Drosophila)	0.036
Hoxc5	homeobox C5	0.036
Tbx2	T-box 2	0.036
En1	engrailed 1	0.035
Foxi1	forkhead box I1	0.034
Hmx1	H6 homeobox 1	0.033
Tcf21	transcription factor 21	0.032
Hoxd3	homeobox D3	0.032
Ptk7	PTK7 protein tyrosine kinase 7	0.031
Esr1	estrogen receptor 1 (alpha)	0.031
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.031
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.030
Insm1	insulinoma-associated 1	0.030
Gli2	GLI-Kruppel family member GLI2	0.030
Gdf11	growth differentiation factor 11	0.030
Ctnnd1	catenin (cadherin associated protein), delta 1	0.029
Pbx1	pre B-cell leukemia transcription factor 1	0.029
Scn5a	sodium channel, voltage-gated, type V, alpha	0.029
Tcf15	transcription factor 15	0.029
Hes1	hairy and enhancer of split 1 (Drosophila)	0.028
Vangl2	vang-like 2 (van gogh, Drosophila)	0.028
Tbx5	T-box 5	0.027
Nkx6-1	NK6 homeobox 1	0.027
Mesp1	mesoderm posterior 1	0.027
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.026
Hoxc8	homeobox C8	0.026
Wnt1	wingless-related MMTV integration site 1	0.026
Efnb1	ephrin B1	0.025
Uncx	UNC homeobox	0.025
Gata3	GATA binding protein 3	0.025
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.025
Fzd4	frizzled homolog 4 (Drosophila)	0.024
Hmx3	H6 homeobox 3	0.024
Sim2	single-minded homolog 2 (Drosophila)	0.024
Adra2b	adrenergic receptor, alpha 2b	0.024
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.024
Ebf3	early B-cell factor 3	0.023
Hoxa13	homeobox A13	0.023
Hoxb1	homeobox B1	0.023
Tcfap2c	transcription factor AP-2, gamma	0.022
Ntf3	neurotrophin 3	0.022
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.022
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.022
Hoxa10	homeobox A10	0.021
Nhlh1	nescient helix loop helix 1	0.021
Neurog2	neurogenin 2	0.021
Npr3	natriuretic peptide receptor 3	0.021
Neurog1	neurogenin 1	0.020
Krt14	keratin 14	0.020
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.020
Sim1	single-minded homolog 1 (Drosophila)	0.020
Tcf4	transcription factor 4	0.020
Hoxc6	homeobox C6	0.019
Gpr50	G-protein-coupled receptor 50	0.019
Dlx5	distal-less homeobox 5	0.019
Snai1	snail homolog 1 (Drosophila)	0.018
Wnt6	wingless-related MMTV integration site 6	0.018
Srrm4	serine/arginine repetitive matrix 4	0.018
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.018
Onecut1	one cut domain, family member 1	0.018
Plac1	placental specific protein 1	0.018
Dchs1	dachsous 1 (Drosophila)	0.017
Hoxd9	homeobox D9	0.017
Dlx1	distal-less homeobox 1	0.017
Psen1	presenilin 1	0.017
Ptf1a	pancreas specific transcription factor, 1a	0.017
Tead4	TEA domain family member 4	0.017
Tbx10	T-box 10	0.017
Vax1	ventral anterior homeobox containing gene 1	0.017
Nog	noggin	0.017
Barx1	BarH-like homeobox 1	0.017
Nkx2-1	NK2 homeobox 1	0.017
Ldb2	LIM domain binding 2	0.017
Tlx1	T-cell leukemia, homeobox 1	0.016
Lmx1b	LIM homeobox transcription factor 1 beta	0.016	Mouse
Smad4	MAD homolog 4 (Drosophila)	0.016
Tbx4	T-box 4	0.016
Meox2	mesenchyme homeobox 2	0.016
Myog	myogenin	0.015
Irx4	Iroquois related homeobox 4 (Drosophila)	0.015
Isl2	insulin related protein 2 (islet 2)	0.015	Mouse
Mef2a	myocyte enhancer factor 2A	0.015	Mouse
Amotl2	angiomotin-like 2	0.015
Nrk	Nik related kinase	0.015
Dlg1	discs, large homolog 1 (Drosophila)	0.015
Foxh1	forkhead box H1	0.015
Zfp503	zinc finger protein 503	0.015
Sspo	SCO-spondin	0.015
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.015
Gas1	growth arrest specific 1	0.015
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.015
She	src homology 2 domain-containing transforming protein E	0.015
Cxadr	coxsackie virus and adenovirus receptor	0.015
Hoxb7	homeobox B7	0.014
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.014
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.014
Fbn2	fibrillin 2	0.014
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.014
Evx1	even skipped homeotic gene 1 homolog	0.014
Ptprb	protein tyrosine phosphatase, receptor type, B	0.014
Dll1	delta-like 1 (Drosophila)	0.014
Fgf18	fibroblast growth factor 18	0.014
Fgf4	fibroblast growth factor 4	0.014
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.014
Hoxa2	homeobox A2	0.014
Hoxb6	homeobox B6	0.014
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.013
Foxd2	forkhead box D2	0.013
Foxe3	forkhead box E3	0.013
Ephb4	Eph receptor B4	0.013
Cacng4	calcium channel, voltage-dependent, gamma subunit 4	0.013
Gpc3	glypican 3	0.013
Trp73	transformation related protein 73	0.013
Gpr27	G protein-coupled receptor 27	0.013
Hoxb4	homeobox B4	0.013
Epha1	Eph receptor A1	0.013
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.013
Foxl2	forkhead box L2	0.012
Col22a1	collagen, type XXII, alpha 1	0.012
Dlx2	distal-less homeobox 2	0.012
Ret	ret proto-oncogene	0.012
Pitx3	paired-like homeodomain transcription factor 3	0.012
Hoxc4	homeobox C4	0.012
Dmbx1	diencephalon/mesencephalon homeobox 1	0.012
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.012
Prdm6	PR domain containing 6	0.012
Sox3	SRY-box containing gene 3	0.012
Runx2	runt related transcription factor 2	0.012
Capn6	calpain 6	0.012
Irx5	Iroquois related homeobox 5 (Drosophila)	0.012
Foxf2	forkhead box F2	0.012
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.012
Emid2	EMI domain containing 2	0.012
Flnc	filamin C, gamma	0.012
Zeb1	zinc finger E-box binding homeobox 1	0.011
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.011
Smad2	MAD homolog 2 (Drosophila)	0.011
Pygo1	pygopus 1	0.011
Wnt9a	wingless-type MMTV integration site 9A	0.011
Pax7	paired box gene 7	0.011
Gsk3b	glycogen synthase kinase 3 beta	0.011
Nos3	nitric oxide synthase 3, endothelial cell	0.011
Tcf12	transcription factor 12	0.011
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.011
Fev	FEV (ETS oncogene family)	0.011
Hoxd10	homeobox D10	0.011
Spnb2	spectrin beta 2	0.011
Wnt11	wingless-related MMTV integration site 11	0.011
Hoxc9	homeobox C9	0.011
Sct	secretin	0.011
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.011
Tbx15	T-box 15	0.011
Kdr	kinase insert domain protein receptor	0.011
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.011
Hmga2	high mobility group AT-hook 2	0.011
2610109H07Rik	RIKEN cDNA 2610109H07 gene	0.011
Klf7	Kruppel-like factor 7 (ubiquitous)	0.010
Sall3	sal-like 3 (Drosophila)	0.010
Notch3	Notch gene homolog 3 (Drosophila)	0.010
Hoxd4	homeobox D4	0.010
Smad7	MAD homolog 7 (Drosophila)	0.010
Msx3	homeobox, msh-like 3	0.010
Tas1r2	taste receptor, type 1, member 2	0.010
Srgap1	SLIT-ROBO Rho GTPase activating protein 1	0.010
Apc	adenomatosis polyposis coli	0.010
Itga3	integrin alpha 3	0.010
Ar	androgen receptor	0.010
Emp2	epithelial membrane protein 2	0.010
Sox17	SRY-box containing gene 17	0.010
Arx	aristaless related homeobox	0.010
Klf6	Kruppel-like factor 6	0.010
Dll4	delta-like 4 (Drosophila)	0.010
Pcdh1	protocadherin 1	0.010
Tlx3	T-cell leukemia, homeobox 3	0.010
Alx3	aristaless-like homeobox 3	0.010