IMP

Process View

Mus musculus

13 genes annotated in mouse

metanephric glomerulus development

The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "metanephric glomerulus development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "metanephric glomerulus development" (in gray)

Name	Description	Probability	Func Analog Organism
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.994
Ar	androgen receptor	0.987
Pax2	paired box gene 2	0.982
Pax8	paired box gene 8	0.980	Mouse
Nos3	nitric oxide synthase 3, endothelial cell	0.971
Lhx1	LIM homeobox protein 1	0.951	Rat
Flt4	FMS-like tyrosine kinase 4	0.946	Mouse
Lamc1	laminin, gamma 1	0.934	Mouse
Wt1	Wilms tumor 1 homolog	0.930
Emx2	empty spiracles homolog 2 (Drosophila)	0.922
Kdr	kinase insert domain protein receptor	0.906	Mouse
Esr1	estrogen receptor 1 (alpha)	0.904
Kiss1	KiSS-1 metastasis-suppressor	0.870
Foxc2	forkhead box C2	0.825
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.817
Tgfbr2	transforming growth factor, beta receptor II	0.796
Fgfr2	fibroblast growth factor receptor 2	0.685
Ret	ret proto-oncogene	0.637
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.613
Ren1	renin 1 structural	0.545
Amhr2	anti-Mullerian hormone type 2 receptor	0.536
Cga	glycoprotein hormones, alpha subunit	0.530
Shh	sonic hedgehog	0.522
Agtr2	angiotensin II receptor, type 2	0.522
Bmp4	bone morphogenetic protein 4	0.482
Lhx9	LIM homeobox protein 9	0.445
Tbx1	T-box 1	0.421
Fshr	follicle stimulating hormone receptor	0.373	Mouse
Wnt9b	wingless-type MMTV integration site 9B	0.366
Eln	elastin	0.346
Rarg	retinoic acid receptor, gamma	0.338
Vegfa	vascular endothelial growth factor A	0.324	Mouse
Rara	retinoic acid receptor, alpha	0.323
Agtr1a	angiotensin II receptor, type 1a	0.296	Mouse
Foxc1	forkhead box C1	0.267
Hoxa1	homeobox A1	0.266
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.257
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.255
Cdh5	cadherin 5	0.248
Lepr	leptin receptor	0.245
Gdnf	glial cell line derived neurotrophic factor	0.235
Fgf8	fibroblast growth factor 8	0.232
Ghr	growth hormone receptor	0.213
Nid1	nidogen 1	0.207
Hoxa11	homeobox A11	0.204
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.202
Rxra	retinoid X receptor alpha	0.199
Rarb	retinoic acid receptor, beta	0.187
Nab2	Ngfi-A binding protein 2	0.177
Duox2	dual oxidase 2	0.166
Fgf10	fibroblast growth factor 10	0.166
Ptprb	protein tyrosine phosphatase, receptor type, B	0.165
Bcl2	B-cell leukemia/lymphoma 2	0.164
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.164
Lama5	laminin, alpha 5	0.163
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.160
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.160	Mouse
Lep	leptin	0.154
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.148
Fbn1	fibrillin 1	0.136
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.135
Bdkrb2	bradykinin receptor, beta 2	0.130	Mouse
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.123
She	src homology 2 domain-containing transforming protein E	0.121
Hoxa3	homeobox A3	0.120
Csf1	colony stimulating factor 1 (macrophage)	0.098
Gnrh1	gonadotropin releasing hormone 1	0.096
Fbln1	fibulin 1	0.096
Gucy2e	guanylate cyclase 2e	0.094
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.092
Sox18	SRY-box containing gene 18	0.092
Pax3	paired box gene 3	0.091
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.087
Krt15	keratin 15	0.083
Eya1	eyes absent 1 homolog (Drosophila)	0.080
Egr1	early growth response 1	0.078	Mouse Rat
Kiss1r	KISS1 receptor	0.078
Hoxb3	homeobox B3	0.077
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.075
Trp63	transformation related protein 63	0.075
Sox7	SRY-box containing gene 7	0.074
Tbx2	T-box 2	0.069
Wnt4	wingless-related MMTV integration site 4	0.069
Ltbp4	latent transforming growth factor beta binding protein 4	0.066
Tgfb2	transforming growth factor, beta 2	0.062
Smad6	MAD homolog 6 (Drosophila)	0.061
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.060
Plxnd1	plexin D1	0.058
Ahr	aryl-hydrocarbon receptor	0.056
Hoxd11	homeobox D11	0.052
Tyrobp	TYRO protein tyrosine kinase binding protein	0.052
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.051
Col4a3	collagen, type IV, alpha 3	0.048
Prlr	prolactin receptor	0.048
Rem1	rad and gem related GTP binding protein 1	0.047
Wnt6	wingless-related MMTV integration site 6	0.046
Crhr1	corticotropin releasing hormone receptor 1	0.046
Ntn4	netrin 4	0.045	Mouse
Otx1	orthodenticle homolog 1 (Drosophila)	0.044
Itga3	integrin alpha 3	0.044
Apoe	apolipoprotein E	0.043
Nhlh2	nescient helix loop helix 2	0.041
Foxi1	forkhead box I1	0.041
Bglap	bone gamma carboxyglutamate protein	0.040
Phox2b	paired-like homeobox 2b	0.040
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.039
Osr1	odd-skipped related 1 (Drosophila)	0.039
Col4a4	collagen, type IV, alpha 4	0.039
Ptgs1	prostaglandin-endoperoxide synthase 1	0.039
Eng	endoglin	0.038
Bmp6	bone morphogenetic protein 6	0.037
Hoxd10	homeobox D10	0.037
Fos	FBJ osteosarcoma oncogene	0.037
Dhh	desert hedgehog	0.037
Lef1	lymphoid enhancer binding factor 1	0.036
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.036
Ramp2	receptor (calcitonin) activity modifying protein 2	0.035
Efnb2	ephrin B2	0.035
Tmem204	transmembrane protein 204	0.035
Apln	apelin	0.035
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.035
Notch2	Notch gene homolog 2 (Drosophila)	0.033
Npr3	natriuretic peptide receptor 3	0.033
Gja4	gap junction protein, alpha 4	0.032
Fgf3	fibroblast growth factor 3	0.032
Vdr	vitamin D receptor	0.032
Drd2	dopamine receptor D2	0.031
Jag1	jagged 1	0.031
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.031
Adcy4	adenylate cyclase 4	0.030
Cxcl12	chemokine (C-X-C motif) ligand 12	0.029
Foxg1	forkhead box G1	0.029
Lama4	laminin, alpha 4	0.029
Tgfb1	transforming growth factor, beta 1	0.029
Pcdh12	protocadherin 12	0.028
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.028
Sox10	SRY-box containing gene 10	0.028
Lox	lysyl oxidase	0.028
Hoxd13	homeobox D13	0.028
Msx1	homeobox, msh-like 1	0.028
Gbx2	gastrulation brain homeobox 2	0.028
Gnrhr	gonadotropin releasing hormone receptor	0.028
Spry4	sprouty homolog 4 (Drosophila)	0.027
Ptgs2	prostaglandin-endoperoxide synthase 2	0.027
Msln	mesothelin	0.027
Emilin3	elastin microfibril interfacer 3	0.027
Foxf2	forkhead box F2	0.026
Ntf3	neurotrophin 3	0.026
Fgfr1	fibroblast growth factor receptor 1	0.026
Flt1	FMS-like tyrosine kinase 1	0.026	Mouse
Lamb1	laminin B1	0.026	Mouse
Adrb1	adrenergic receptor, beta 1	0.025
Runx3	runt related transcription factor 3	0.025
Ldlr	low density lipoprotein receptor	0.024
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.024
Drap1	Dr1 associated protein 1 (negative cofactor 2 alpha)	0.024
Lama1	laminin, alpha 1	0.023
Nkx2-1	NK2 homeobox 1	0.023
Hand2	heart and neural crest derivatives expressed transcript 2	0.023
Tg	thyroglobulin	0.023
Twist2	twist homolog 2 (Drosophila)	0.023
Ltbp1	latent transforming growth factor beta binding protein 1	0.022
Shbg	sex hormone binding globulin	0.022
Esr2	estrogen receptor 2 (beta)	0.022
Foxf1a	forkhead box F1a	0.022
Lhx3	LIM homeobox protein 3	0.022
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.022
Kcnk3	potassium channel, subfamily K, member 3	0.022
Dpep1	dipeptidase 1 (renal)	0.022
Csf3	colony stimulating factor 3 (granulocyte)	0.022
Ctnnb1	catenin (cadherin associated protein), beta 1	0.021
Nrtn	neurturin	0.021
Vegfc	vascular endothelial growth factor C	0.020	Mouse
Amh	anti-Mullerian hormone	0.020
Hoxd9	homeobox D9	0.020
Aoc3	amine oxidase, copper containing 3	0.019
Cbl	Casitas B-lineage lymphoma	0.019
Acvrl1	activin A receptor, type II-like 1	0.019
Gab2	growth factor receptor bound protein 2-associated protein 2	0.019
Pou4f2	POU domain, class 4, transcription factor 2	0.019
Tnxb	tenascin XB	0.019
Tcf21	transcription factor 21	0.018
Ltbp2	latent transforming growth factor beta binding protein 2	0.018
Vgf	VGF nerve growth factor inducible	0.018
A4galt	alpha 1,4-galactosyltransferase	0.018
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.018
Tenc1	tensin like C1 domain-containing phosphatase	0.017
Pdgfc	platelet-derived growth factor, C polypeptide	0.017
Hoxa2	homeobox A2	0.017
Gata6	GATA binding protein 6	0.017
Tcf23	transcription factor 23	0.017	Mouse
Scnn1g	sodium channel, nonvoltage-gated 1 gamma	0.017
Thbd	thrombomodulin	0.017
Robo3	roundabout homolog 3 (Drosophila)	0.016
Prx	periaxin	0.016
Inha	inhibin alpha	0.016
Cmklr1	chemokine-like receptor 1	0.016
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.016
Mrvi1	MRV integration site 1	0.016
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.016
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.015
Hoxd3	homeobox D3	0.015
Meox1	mesenchyme homeobox 1	0.015
Dusp1	dual specificity phosphatase 1	0.015
Sox17	SRY-box containing gene 17	0.015
Gaa	glucosidase, alpha, acid	0.015
Cldn5	claudin 5	0.015
Tek	endothelial-specific receptor tyrosine kinase	0.014
Ly86	lymphocyte antigen 86	0.014
Podxl	podocalyxin-like	0.014
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.014
Fst	follistatin	0.014
Nos1	nitric oxide synthase 1, neuronal	0.014
Hbegf	heparin-binding EGF-like growth factor	0.014
Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1	0.014
Grap2	GRB2-related adaptor protein 2	0.014
Egr2	early growth response 2	0.014	Mouse
Hoxd8	homeobox D8	0.013
Fxyd2	FXYD domain-containing ion transport regulator 2	0.013
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.013
Fzd4	frizzled homolog 4 (Drosophila)	0.013
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.013
Col4a6	collagen, type IV, alpha 6	0.013
Lmx1b	LIM homeobox transcription factor 1 beta	0.013
Klk1b9	kallikrein 1-related peptidase b9	0.013
Hoxb6	homeobox B6	0.013
Olfr90	olfactory receptor 90	0.013
Otx2	orthodenticle homolog 2 (Drosophila)	0.013
Kl	klotho	0.013
Prss12	protease, serine, 12 neurotrypsin (motopsin)	0.013
Ngf	nerve growth factor	0.013
Capn9	calpain 9	0.013
Gata3	GATA binding protein 3	0.012
Ldb2	LIM domain binding 2	0.012
Hoxa4	homeobox A4	0.012
Gli2	GLI-Kruppel family member GLI2	0.012
Sftpd	surfactant associated protein D	0.012
Ptk7	PTK7 protein tyrosine kinase 7	0.012
Itgb3	integrin beta 3	0.012
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.012
Zeb1	zinc finger E-box binding homeobox 1	0.012
Vangl2	vang-like 2 (van gogh, Drosophila)	0.012
Sphk1	sphingosine kinase 1	0.012
Sct	secretin	0.012
Tgfbr3	transforming growth factor, beta receptor III	0.012
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.012
Thra	thyroid hormone receptor alpha	0.012
Itga8	integrin alpha 8	0.012
Src	Rous sarcoma oncogene	0.012
Robo2	roundabout homolog 2 (Drosophila)	0.012
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.011
Ednra	endothelin receptor type A	0.011
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.011
Gja1	gap junction protein, alpha 1	0.011
Bcl6b	B-cell CLL/lymphoma 6, member B	0.011
Ltc4s	leukotriene C4 synthase	0.011
Mkl2	MKL/myocardin-like 2	0.011
Ednrb	endothelin receptor type B	0.011
Cav1	caveolin 1, caveolae protein	0.011
Pkp1	plakophilin 1	0.011
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.011
Prph	peripherin	0.011
Aebp1	AE binding protein 1	0.011
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.011
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.011
Inhba	inhibin beta-A	0.010
Oprd1	opioid receptor, delta 1	0.010
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.010
Bmp2	bone morphogenetic protein 2	0.010
Mmrn2	multimerin 2	0.010
Ddr2	discoidin domain receptor family, member 2	0.010
Mdfi	MyoD family inhibitor	0.010
Cnga3	cyclic nucleotide gated channel alpha 3	0.010
Pgr	progesterone receptor	0.010
Cpz	carboxypeptidase Z	0.010
Col13a1	collagen, type XIII, alpha 1	0.010
Il9r	interleukin 9 receptor	0.010
Gli3	GLI-Kruppel family member GLI3	0.010
Ccbp2	chemokine binding protein 2	0.010
Zfp503	zinc finger protein 503	0.010
Grid2	glutamate receptor, ionotropic, delta 2	0.010
Lamc3	laminin gamma 3	0.010	Mouse
Fgfrl1	fibroblast growth factor receptor-like 1	0.010