Mus musculus

26 known processes

Lrp2

low density lipoprotein receptor-related protein 2

(Aliases: Gp330,AI315343,AW536255,Megalin,D230004K18Rik)

Lrp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.917
kidney development GO:0001822 213 0.820
Mouse
neural tube formation GO:0001841 108 0.815
Mouse
stem cell development GO:0048864 219 0.784
Mouse
smoothened signaling pathway GO:0007224 105 0.767
response to fibroblast growth factor GO:0071774 47 0.760
organic anion transport GO:0015711 137 0.756
forebrain development GO:0030900 302 0.742
pallium development GO:0021543 120 0.727
Mouse
axonogenesis GO:0007409 274 0.727
Mouse
appendage development GO:0048736 166 0.718
Mouse
transmembrane transport GO:0055085 412 0.705
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.701
synaptic transmission GO:0007268 329 0.694
skeletal system morphogenesis GO:0048705 203 0.668
Mouse
trachea cartilage morphogenesis GO:0060535 4 0.667
Mouse
endocytosis GO:0006897 168 0.663
cellular response to growth factor stimulus GO:0071363 197 0.646
regulation of establishment of planar polarity GO:0090175 28 0.644
Mouse
stem cell differentiation GO:0048863 268 0.624
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.610
primary neural tube formation GO:0014020 95 0.607
Mouse
embryonic skeletal system development GO:0048706 120 0.606
ameboidal type cell migration GO:0001667 128 0.598
Mouse
lipid transport GO:0006869 98 0.593
Mouse Worm
regulation of organ morphogenesis GO:2000027 144 0.572
Mouse
anion transport GO:0006820 177 0.562
lung development GO:0030324 164 0.552
embryonic appendage morphogenesis GO:0035113 126 0.543
Mouse
stem cell proliferation GO:0072089 117 0.540
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.539
Mouse
forebrain cell migration GO:0021885 58 0.537
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.532
Mouse
digestive tract morphogenesis GO:0048546 147 0.521
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.520
cell migration involved in gastrulation GO:0042074 13 0.517
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.506
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.482
Mouse
neural tube development GO:0021915 160 0.480
Mouse
skeletal system development GO:0001501 356 0.479
Mouse
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.479
Mouse
regionalization GO:0003002 337 0.470
Mouse
gastrulation GO:0007369 116 0.466
Mouse
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.463
spinal cord development GO:0021510 81 0.463
negative regulation of wnt signaling pathway GO:0030178 73 0.463
Mouse
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.456
epithelial tube morphogenesis GO:0060562 303 0.442
Mouse
glial cell differentiation GO:0010001 131 0.417
Mouse
respiratory system development GO:0060541 190 0.409
Mouse
cerebral cortex cell migration GO:0021795 44 0.409
Mouse
embryonic limb morphogenesis GO:0030326 126 0.407
Mouse
cerebral cortex development GO:0021987 86 0.406
Mouse
kidney morphogenesis GO:0060993 83 0.403
tube closure GO:0060606 91 0.396
Mouse
appendage morphogenesis GO:0035107 149 0.395
Mouse
response to growth factor GO:0070848 198 0.394
anion transmembrane transport GO:0098656 71 0.389
muscle tissue development GO:0060537 308 0.387
Mouse
morphogenesis of a polarized epithelium GO:0001738 37 0.384
respiratory tube development GO:0030323 167 0.382
embryonic organ morphogenesis GO:0048562 276 0.379
Mouse
protein targeting GO:0006605 143 0.379
Mouse
lung morphogenesis GO:0060425 50 0.378
renal system development GO:0072001 225 0.376
Mouse
embryonic heart tube morphogenesis GO:0003143 51 0.372
Mouse
digestive system development GO:0055123 200 0.371
Mouse
embryonic camera type eye development GO:0031076 36 0.366
Mouse
endodermal cell fate specification GO:0001714 4 0.366
regulation of bmp signaling pathway GO:0030510 60 0.365
epithelial cell development GO:0002064 159 0.363
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.359
nephron development GO:0072006 109 0.355
regulation of phospholipase a2 activity GO:0032429 3 0.354
Mouse
muscle cell differentiation GO:0042692 261 0.344
organic hydroxy compound transport GO:0015850 93 0.333
Mouse Worm
cardiac chamber morphogenesis GO:0003206 93 0.329
Mouse
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.318
Mouse
blood vessel morphogenesis GO:0048514 285 0.312
Mouse
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.307
Mouse
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.304
regulation of clathrin mediated endocytosis GO:2000369 4 0.304
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.303
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.301
limb morphogenesis GO:0035108 149 0.297
Mouse
positive regulation of growth GO:0045927 104 0.296
Worm
negative regulation of growth GO:0045926 99 0.295
chondrocyte differentiation GO:0002062 72 0.294
regulation of apoptotic signaling pathway GO:2001233 197 0.292
wnt signaling pathway GO:0016055 188 0.292
Mouse
embryonic epithelial tube formation GO:0001838 130 0.292
Mouse
negative regulation of sterol transport GO:0032372 4 0.290
Mouse
tube formation GO:0035148 140 0.285
Mouse
regulation of ion transport GO:0043269 215 0.285
midbrain development GO:0030901 35 0.282
Mouse
blastocyst development GO:0001824 80 0.281
fat cell differentiation GO:0045444 160 0.281
Mouse
striated muscle tissue development GO:0014706 293 0.277
Mouse
regulation of ion transmembrane transporter activity GO:0032412 54 0.276
ureteric bud morphogenesis GO:0060675 62 0.275
multicellular organismal homeostasis GO:0048871 164 0.272
Mouse
regulation of neuron projection development GO:0010975 169 0.270
Mouse
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.270
Mouse
amino acid transmembrane transport GO:0003333 37 0.269
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.265
epithelial tube formation GO:0072175 130 0.263
Mouse
regulation of mesenchymal cell proliferation GO:0010464 37 0.256
Mouse
lipid localization GO:0010876 126 0.254
Mouse Worm
negative regulation of cell development GO:0010721 169 0.252
Mouse
c21 steroid hormone biosynthetic process GO:0006700 3 0.251
positive regulation of ossification GO:0045778 47 0.250
Mouse
synapse organization GO:0050808 125 0.245
Mouse
cardiac septum development GO:0003279 59 0.243
Mouse
ossification GO:0001503 216 0.237
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.237
mapk cascade GO:0000165 281 0.236
Mouse
regulation of neuron death GO:1901214 134 0.234
telencephalon development GO:0021537 186 0.234
Mouse
angiogenesis GO:0001525 201 0.234
Mouse
outflow tract morphogenesis GO:0003151 53 0.231
Mouse
membrane organization GO:0061024 245 0.231
Mouse
negative regulation of cell fate specification GO:0009996 4 0.231
mesoderm formation GO:0001707 62 0.231
intrinsic apoptotic signaling pathway GO:0097193 132 0.231
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.228
Mouse
establishment of organelle localization GO:0051656 122 0.227
renal tubule development GO:0061326 87 0.227
locomotory behavior GO:0007626 195 0.227
nitrogen compound transport GO:0071705 271 0.226
Mouse
axon guidance GO:0007411 141 0.226
sensory perception GO:0007600 245 0.225
positive regulation of wnt signaling pathway GO:0030177 45 0.225
cerebellum morphogenesis GO:0021587 42 0.224
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.224
Mouse
cardiac chamber development GO:0003205 108 0.222
Mouse
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.222
Mouse
endoderm development GO:0007492 45 0.218
mesenchyme development GO:0060485 152 0.218
Mouse
axis elongation GO:0003401 30 0.216
Mouse
urogenital system development GO:0001655 261 0.215
Mouse
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 10 0.213
Mouse
cardiac atrium morphogenesis GO:0003209 23 0.212
Mouse
renal vesicle induction GO:0072034 3 0.212
positive regulation of cell migration GO:0030335 109 0.209
positive regulation of nervous system development GO:0051962 221 0.209
Mouse
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.208
male germ line sex determination GO:0019100 2 0.207
organic hydroxy compound metabolic process GO:1901615 203 0.207
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.207
potassium ion homeostasis GO:0055075 4 0.207
apoptotic signaling pathway GO:0097190 306 0.206
positive regulation of smoothened signaling pathway GO:0045880 23 0.205
bone development GO:0060348 120 0.203
Mouse
limb development GO:0060173 166 0.203
Mouse
neural tube patterning GO:0021532 43 0.203
Mouse
neural tube closure GO:0001843 90 0.202
Mouse
dendrite development GO:0016358 115 0.201
male sex differentiation GO:0046661 109 0.199
epithelial tube branching involved in lung morphogenesis GO:0060441 28 0.198
primary prostatic bud elongation GO:0060516 2 0.197
inorganic cation transmembrane transport GO:0098662 207 0.196
regulation of ion transmembrane transport GO:0034765 119 0.196
blastocyst formation GO:0001825 33 0.194
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.193
organelle localization GO:0051640 179 0.193
positive regulation of striated muscle tissue development GO:0045844 31 0.191
hair follicle development GO:0001942 85 0.190
Mouse
mesonephric tubule development GO:0072164 94 0.189
skeletal muscle tissue regeneration GO:0043403 20 0.188
retina morphogenesis in camera type eye GO:0060042 45 0.185
Mouse
positive regulation of mapk cascade GO:0043410 170 0.185
Mouse
epithelial cell proliferation GO:0050673 174 0.184
Mouse
establishment of tissue polarity GO:0007164 28 0.183
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.182
Mouse
endothelium development GO:0003158 45 0.180
regulation of cardiac muscle tissue development GO:0055024 31 0.180
Mouse
regulation of body fluid levels GO:0050878 162 0.179
regulation of muscle tissue development GO:1901861 97 0.179
Mouse
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.179
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.178
epithelial mesenchymal signaling involved in prostate gland development GO:0060738 2 0.174
peptide transport GO:0015833 133 0.173
Mouse
glutamate receptor signaling pathway GO:0007215 35 0.173
non canonical wnt signaling pathway GO:0035567 33 0.172
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.171
Mouse
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.171
bmp signaling pathway GO:0030509 93 0.171
epithelium migration GO:0090132 63 0.171
renal system process GO:0003014 48 0.171
regulation of endocytosis GO:0030100 69 0.170
response to organic cyclic compound GO:0014070 198 0.170
Mouse
regulation of embryonic development GO:0045995 71 0.169
Mouse
neuron projection guidance GO:0097485 141 0.168
negative regulation of nervous system development GO:0051961 156 0.168
Mouse
establishment of planar polarity GO:0001736 28 0.167
cerebral cortex radially oriented cell migration GO:0021799 31 0.166
glycerolipid metabolic process GO:0046486 122 0.165
sensory organ morphogenesis GO:0090596 242 0.164
Mouse
ear morphogenesis GO:0042471 118 0.163
regulation of stem cell differentiation GO:2000736 50 0.163
metencephalon development GO:0022037 89 0.162
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.160
Mouse
regulation of smoothened signaling pathway GO:0008589 58 0.159
nephron morphogenesis GO:0072028 69 0.159
nephron epithelium morphogenesis GO:0072088 68 0.158
regulation of cardiac cell fate specification GO:2000043 1 0.158
metanephros development GO:0001656 79 0.155
septum primum development GO:0003284 4 0.155
left lung development GO:0060459 4 0.154
negative regulation of molecular function GO:0044092 258 0.153
neuron projection extension GO:1990138 64 0.153
response to transforming growth factor beta GO:0071559 88 0.152
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.152
Mouse
regulation of epithelial to mesenchymal transition GO:0010717 22 0.151
morphogenesis of a branching epithelium GO:0061138 193 0.151
Mouse
negative regulation of cell proliferation GO:0008285 296 0.149
Mouse
telencephalon cell migration GO:0022029 55 0.149
Mouse
regulation of angiogenesis GO:0045765 81 0.149
regulation of protein localization GO:0032880 231 0.148
tendon cell differentiation GO:0035990 4 0.147
renal tubule morphogenesis GO:0061333 72 0.147
somatic stem cell maintenance GO:0035019 47 0.146
Mouse
negative regulation of cholesterol transport GO:0032375 4 0.144
Mouse
kidney epithelium development GO:0072073 121 0.144
motor neuron migration GO:0097475 4 0.143
response to reactive oxygen species GO:0000302 56 0.143
regulation of sterol transport GO:0032371 17 0.143
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.142
wound healing GO:0042060 157 0.142
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.141
nephron tubule development GO:0072080 84 0.139
insulin secretion GO:0030073 89 0.139
Mouse
mesonephric duct morphogenesis GO:0072180 4 0.139
steroid metabolic process GO:0008202 119 0.137
Mouse
adult behavior GO:0030534 135 0.137
cardiac septum morphogenesis GO:0060411 46 0.137
Mouse
extracellular matrix organization GO:0030198 147 0.137
receptor mediated endocytosis GO:0006898 51 0.136
axis elongation involved in somitogenesis GO:0090245 4 0.136
Mouse
regulation of hippo signaling GO:0035330 1 0.136
canonical wnt signaling pathway GO:0060070 130 0.136
Mouse
cell proliferation in hindbrain GO:0021534 10 0.136
Mouse
regulation of non canonical wnt signaling pathway GO:2000050 12 0.134
Mouse
skeletal muscle fiber development GO:0048741 58 0.134
metanephric mesenchymal cell proliferation involved in metanephros development GO:0072136 2 0.133
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.132
myotube cell development GO:0014904 60 0.131
heart morphogenesis GO:0003007 178 0.129
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 82 0.129
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.129
negative regulation of intracellular signal transduction GO:1902532 167 0.128
retina development in camera type eye GO:0060041 119 0.127
Mouse
regulation of transporter activity GO:0032409 57 0.127
positive regulation of stem cell proliferation GO:2000648 59 0.126
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.126
branching involved in ureteric bud morphogenesis GO:0001658 56 0.125
positive regulation of cell cycle GO:0045787 92 0.124
endocrine system development GO:0035270 98 0.124
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.124
Mouse
positive regulation of endocytosis GO:0045807 42 0.124
myeloid cell differentiation GO:0030099 233 0.123
development of primary male sexual characteristics GO:0046546 88 0.123
peptide hormone secretion GO:0030072 109 0.122
Mouse
positive regulation of angiogenesis GO:0045766 46 0.122
response to extracellular stimulus GO:0009991 127 0.122
Mouse
astrocyte fate commitment GO:0060018 4 0.121
nephron tubule morphogenesis GO:0072078 68 0.121
regulation of cell projection organization GO:0031344 206 0.121
Mouse
vesicle localization GO:0051648 86 0.120
ureter morphogenesis GO:0072197 4 0.120
cellular amino acid metabolic process GO:0006520 103 0.119
regulation of cell motility GO:2000145 236 0.119
Mouse Worm
positive regulation of bmp signaling pathway GO:0030513 23 0.119
hindbrain morphogenesis GO:0021575 46 0.118
Mouse
establishment of vesicle localization GO:0051650 81 0.118
oviduct development GO:0060066 3 0.117
bronchiole development GO:0060435 3 0.117
hair cycle GO:0042633 90 0.116
Mouse
anatomical structure homeostasis GO:0060249 145 0.116
Mouse
central nervous system neuron differentiation GO:0021953 162 0.116
diencephalon development GO:0021536 63 0.114
Mouse
myotube differentiation GO:0014902 105 0.114
mesendoderm development GO:0048382 3 0.114
regulation of transmembrane transport GO:0034762 128 0.114
mesodermal cell migration GO:0008078 4 0.113
response to epidermal growth factor GO:0070849 4 0.112
regulation of hormone levels GO:0010817 211 0.112
Mouse
nucleoside metabolic process GO:0009116 246 0.112
determination of left right symmetry GO:0007368 80 0.111
Mouse
positive regulation of cell development GO:0010720 237 0.111
cell cell signaling involved in mammary gland development GO:0060764 2 0.111
Mouse
endomembrane system organization GO:0010256 147 0.111
negative regulation of mesodermal cell fate specification GO:0042662 3 0.110
development of primary sexual characteristics GO:0045137 143 0.110
epithelial to mesenchymal transition GO:0001837 47 0.110
nephron epithelium development GO:0072009 92 0.109
digestive tract development GO:0048565 190 0.109
Mouse
positive regulation of cell motility GO:2000147 116 0.109
regulation of action potential GO:0098900 4 0.109
response to radiation GO:0009314 165 0.109
regulation of mapk cascade GO:0043408 248 0.108
Mouse
regulation of heart morphogenesis GO:2000826 22 0.108
Mouse
regulation of synaptic transmission glutamatergic GO:0051966 19 0.108
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.107
Mouse
retina vasculature development in camera type eye GO:0061298 17 0.106
Mouse
segmentation GO:0035282 93 0.106
Mouse
hindlimb morphogenesis GO:0035137 42 0.105
Mouse
establishment of synaptic vesicle localization GO:0097480 57 0.105
response to acid chemical GO:0001101 111 0.105
Mouse
cholesterol transport GO:0030301 38 0.104
Mouse
myoblast proliferation GO:0051450 11 0.103
positive regulation of muscle tissue development GO:1901863 32 0.103
positive regulation of dna templated transcription elongation GO:0032786 2 0.103
negative regulation of cell growth GO:0030308 44 0.101
mesonephric epithelium development GO:0072163 94 0.101
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.101
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.101
Mouse
tissue regeneration GO:0042246 22 0.101
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.100
neural crest cell migration GO:0001755 32 0.100
protein import into nucleus GO:0006606 95 0.100
Mouse
camera type eye development GO:0043010 266 0.100
Mouse
protein localization to membrane GO:0072657 108 0.100
Mouse
cell type specific apoptotic process GO:0097285 268 0.100
gonad development GO:0008406 141 0.099
branching involved in salivary gland morphogenesis GO:0060445 26 0.099
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.099
ubiquitin dependent protein catabolic process GO:0006511 129 0.099
Mouse
skeletal muscle organ development GO:0060538 163 0.099
regulation of stem cell proliferation GO:0072091 78 0.098
Mouse
regulation of osteoblast proliferation GO:0033688 15 0.098
Mouse
cardiac right atrium morphogenesis GO:0003213 3 0.098
Mouse
somite development GO:0061053 81 0.098
Mouse
embryonic eye morphogenesis GO:0048048 29 0.097
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.097
closure of optic fissure GO:0061386 2 0.097
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.096
determination of heart left right asymmetry GO:0061371 48 0.096
Mouse
regulation of cellular catabolic process GO:0031329 242 0.096
Mouse
embryonic heart tube development GO:0035050 65 0.096
Mouse
oxidation reduction process GO:0055114 342 0.095
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.095
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.095
Mouse
brain morphogenesis GO:0048854 32 0.095
regulation of cell adhesion GO:0030155 154 0.095
female sex differentiation GO:0046660 84 0.094
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.093
Mouse
adult locomotory behavior GO:0008344 91 0.093
regulation of organelle organization GO:0033043 289 0.093
Mouse
cellular ketone metabolic process GO:0042180 84 0.093
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.093
neuron apoptotic process GO:0051402 142 0.092
positive regulation of ureteric bud formation GO:0072107 3 0.092
epithelial cell migration GO:0010631 63 0.092
neuron migration GO:0001764 122 0.092
negative regulation of cholesterol efflux GO:0090370 4 0.091
Mouse
morphogenesis of an epithelial sheet GO:0002011 27 0.089
Mouse
endocardial cell differentiation GO:0060956 4 0.088
establishment of protein localization to organelle GO:0072594 118 0.088
Mouse
sodium ion transmembrane transport GO:0035725 49 0.088
regulation of cellular response to stress GO:0080135 159 0.087
hematopoietic progenitor cell differentiation GO:0002244 143 0.087
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.086
endodermal cell fate determination GO:0007493 2 0.086
lateral motor column neuron migration GO:0097477 3 0.085
odontogenesis of dentin containing tooth GO:0042475 66 0.085
Mouse
spermatogenesis GO:0007283 284 0.085
mesenchymal cell proliferation GO:0010463 44 0.085
Mouse
regulation of hydrolase activity GO:0051336 246 0.085
Mouse
single organismal cell cell adhesion GO:0016337 131 0.084
cilium morphogenesis GO:0060271 102 0.084
regulation of neuron differentiation GO:0045664 281 0.084
Mouse
nephric duct formation GO:0072179 4 0.084
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.083
Mouse
mesenchymal cell development GO:0014031 93 0.083
anatomical structure arrangement GO:0048532 20 0.083
stem cell division GO:0017145 30 0.082
Mouse
regulation of receptor activity GO:0010469 41 0.082
pyramidal neuron migration GO:0021852 1 0.081
mesoderm development GO:0007498 100 0.081
intracellular protein transport GO:0006886 204 0.081
Mouse
male gonad development GO:0008584 88 0.081
trophectodermal cell differentiation GO:0001829 21 0.081
placenta development GO:0001890 140 0.081
pituitary gland development GO:0021983 38 0.079
morphogenesis of a branching structure GO:0001763 203 0.079
Mouse
acylglycerol metabolic process GO:0006639 55 0.078
cerebellar granule cell precursor proliferation GO:0021930 10 0.078
Mouse
neutral lipid metabolic process GO:0006638 57 0.078
carboxylic acid transport GO:0046942 100 0.078
protein oxidation GO:0018158 2 0.078
organic acid transport GO:0015849 101 0.078
dna metabolic process GO:0006259 303 0.077
tendon formation GO:0035992 4 0.077
neuron death GO:0070997 154 0.077
regulation of cell cycle GO:0051726 281 0.077
renal vesicle morphogenesis GO:0072077 15 0.077
negative regulation of prostatic bud formation GO:0060686 4 0.076
positive regulation of protein kinase b signaling GO:0051897 32 0.076
hormone metabolic process GO:0042445 86 0.075
myeloid leukocyte differentiation GO:0002573 119 0.074
regulation of epithelial cell migration GO:0010632 35 0.074
ventricular septum morphogenesis GO:0060412 27 0.073
Mouse
regulation of systemic arterial blood pressure GO:0003073 61 0.073
regulation of cytoskeleton organization GO:0051493 122 0.073
Mouse
mesoderm morphogenesis GO:0048332 64 0.073
glial cell development GO:0021782 54 0.073
renal capsule morphogenesis GO:0072128 1 0.072
regulation of establishment of protein localization GO:0070201 181 0.072
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.072
Mouse
cellular response to oxidative stress GO:0034599 76 0.072
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.071
cellular lipid metabolic process GO:0044255 323 0.071
peptide metabolic process GO:0006518 46 0.071
cellular transition metal ion homeostasis GO:0046916 32 0.070
inner ear morphogenesis GO:0042472 101 0.070
cation transport GO:0006812 399 0.070
sodium ion transport GO:0006814 73 0.069
negative regulation of kidney development GO:0090185 15 0.069
activation of mapkk activity GO:0000186 15 0.069
Mouse
positive regulation of osteoblast proliferation GO:0033690 9 0.068
Mouse
artery development GO:0060840 53 0.068
Mouse
mesenchymal cell differentiation GO:0048762 107 0.068
Mouse
regulation of chondrocyte differentiation GO:0032330 33 0.068
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.068
microtubule based transport GO:0010970 50 0.068
sensory perception of sound GO:0007605 97 0.067
forelimb morphogenesis GO:0035136 40 0.067
Mouse
cell proliferation involved in heart morphogenesis GO:0061323 15 0.067
Mouse
protein catabolic process GO:0030163 221 0.067
Mouse
folic acid containing compound metabolic process GO:0006760 3 0.067
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.067
gland development GO:0048732 330 0.066
Mouse
positive regulation of programmed cell death GO:0043068 218 0.066
Mouse
mesonephric tubule morphogenesis GO:0072171 63 0.066
regulation of cholesterol efflux GO:0010874 13 0.066
Mouse
notch signaling pathway GO:0007219 71 0.066
molting cycle GO:0042303 90 0.066
Mouse Worm
gliogenesis GO:0042063 141 0.066
Mouse
apoptotic process involved in morphogenesis GO:0060561 25 0.065
Mouse
lung alveolus development GO:0048286 45 0.065
regulation of cell growth GO:0001558 91 0.065
amino acid transport GO:0006865 61 0.065
peptide secretion GO:0002790 114 0.065
Mouse
formation of radial glial scaffolds GO:0021943 4 0.065
Mouse
cell migration in hindbrain GO:0021535 16 0.065
Mouse
formation of organ boundary GO:0010160 1 0.064
head morphogenesis GO:0060323 34 0.064
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 35 0.063
striated muscle cell development GO:0055002 125 0.063
stem cell fate specification GO:0048866 3 0.063
endothelial cell differentiation GO:0045446 41 0.063
formation of primary germ layer GO:0001704 77 0.063
spinal cord motor neuron migration GO:0097476 4 0.063
cochlea morphogenesis GO:0090103 22 0.062
metanephric nephron tubule formation GO:0072289 4 0.062
odontogenesis GO:0042476 78 0.062
Mouse
regulation of cell migration GO:0030334 219 0.062
Mouse Worm
cell cell adhesion GO:0098609 41 0.061
regulation of protein targeting GO:1903533 61 0.061
regulation of renal sodium excretion GO:0035813 3 0.061
prostate gland morphogenetic growth GO:0060737 4 0.061
male gamete generation GO:0048232 285 0.061
prostate gland development GO:0030850 48 0.060
negative regulation of gastrulation GO:2000542 3 0.060
regulation of kinase activity GO:0043549 249 0.060
Mouse
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.060
mammary placode formation GO:0060596 4 0.060
Mouse
cardiac endothelial cell differentiation GO:0003348 4 0.059
retinal blood vessel morphogenesis GO:0061304 3 0.059
hindbrain radial glia guided cell migration GO:0021932 12 0.059
Mouse
glycosyl compound catabolic process GO:1901658 206 0.059
cellular response to extracellular stimulus GO:0031668 81 0.059
positive regulation of protein kinase activity GO:0045860 144 0.058
Mouse
regulation of cartilage development GO:0061035 44 0.058
protein kinase b signaling GO:0043491 74 0.058
roof plate formation GO:0021509 1 0.058
polarity specification of proximal distal axis GO:0010085 2 0.058
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.057
epidermal growth factor receptor signaling pathway GO:0007173 28 0.057
Mouse
stem cell maintenance GO:0019827 130 0.057
Mouse
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.057
bronchiole morphogenesis GO:0060436 1 0.057
membrane depolarization GO:0051899 64 0.057
lung induction GO:0060492 3 0.056
heart formation GO:0060914 16 0.056
cell fate commitment GO:0045165 210 0.056
intraspecies interaction between organisms GO:0051703 21 0.056
positive regulation of lipid transport GO:0032370 22 0.056
Mouse
embryonic viscerocranium morphogenesis GO:0048703 8 0.056
axon extension involved in axon guidance GO:0048846 14 0.055
synaptic vesicle transport GO:0048489 57 0.055
regulation of mesodermal cell fate specification GO:0042661 5 0.055
positive regulation of neural precursor cell proliferation GO:2000179 42 0.055
Mouse
positive regulation of hh target transcription factor activity GO:0007228 3 0.055
formation of anatomical boundary GO:0048859 6 0.055
negative regulation of binding GO:0051100 39 0.054
trachea development GO:0060438 18 0.054
Mouse

Lrp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.118