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Mus musculus

15 genes annotated in mouse

cell proliferation involved in heart morphogenesis

The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell proliferation involved in heart morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cell proliferation involved in heart morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Pitx2	paired-like homeodomain transcription factor 2	0.999
Otx2	orthodenticle homolog 2 (Drosophila)	0.998
Gli3	GLI-Kruppel family member GLI3	0.995
Fgfr2	fibroblast growth factor receptor 2	0.990
Pax2	paired box gene 2	0.975
Eya1	eyes absent 1 homolog (Drosophila)	0.971
Sox2	SRY-box containing gene 2	0.964	Mouse
Fgf8	fibroblast growth factor 8	0.962
Hes1	hairy and enhancer of split 1 (Drosophila)	0.941
Tbx3	T-box 3	0.922	Mouse
Pax3	paired box gene 3	0.921
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.918
Pax6	paired box gene 6	0.915
Prrx1	paired related homeobox 1	0.907
Bmp4	bone morphogenetic protein 4	0.903	Human
Fgfr1	fibroblast growth factor receptor 1	0.879
Hand2	heart and neural crest derivatives expressed transcript 2	0.878
Hand1	heart and neural crest derivatives expressed transcript 1	0.873	Mouse
Tbx1	T-box 1	0.800
Jag1	jagged 1	0.771
Nodal	nodal	0.752	Mouse
Hoxa1	homeobox A1	0.743
Pitx1	paired-like homeodomain transcription factor 1	0.742	Mouse
Foxg1	forkhead box G1	0.729
Rarg	retinoic acid receptor, gamma	0.720
Ctnnb1	catenin (cadherin associated protein), beta 1	0.712
Smad6	MAD homolog 6 (Drosophila)	0.709	Mouse
Notch1	Notch gene homolog 1 (Drosophila)	0.688	Rat
Gata4	GATA binding protein 4	0.659
Foxc2	forkhead box C2	0.634
Isl1	ISL1 transcription factor, LIM/homeodomain	0.624
En1	engrailed 1	0.620
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.618
Hoxa13	homeobox A13	0.612
Emx2	empty spiracles homolog 2 (Drosophila)	0.573
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.567
Gbx2	gastrulation brain homeobox 2	0.554
Foxc1	forkhead box C1	0.541
Chd7	chromodomain helicase DNA binding protein 7	0.536
Snai1	snail homolog 1 (Drosophila)	0.516
Tcfap2a	transcription factor AP-2, alpha	0.463
Smo	smoothened homolog (Drosophila)	0.431
Hoxd13	homeobox D13	0.418
Gata3	GATA binding protein 3	0.353
Bmp7	bone morphogenetic protein 7	0.351	Mouse
Smad3	MAD homolog 3 (Drosophila)	0.316	Mouse
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.306
Lmx1a	LIM homeobox transcription factor 1 alpha	0.302	Mouse
Zic3	zinc finger protein of the cerebellum 3	0.276
Lhx1	LIM homeobox protein 1	0.271	Mouse
Nog	noggin	0.257
Msx2	homeobox, msh-like 2	0.250
Msx1	homeobox, msh-like 1	0.243
Tbx2	T-box 2	0.240	Mouse
Hoxa11	homeobox A11	0.236
Gsc	goosecoid homeobox	0.232
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.225
Vegfa	vascular endothelial growth factor A	0.223
Neurog2	neurogenin 2	0.218	Mouse
Fgfr3	fibroblast growth factor receptor 3	0.203
Zeb1	zinc finger E-box binding homeobox 1	0.202
Wt1	Wilms tumor 1 homolog	0.195
Emx1	empty spiracles homolog 1 (Drosophila)	0.194
Pbx1	pre B-cell leukemia transcription factor 1	0.194
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.186	Mouse
Gli2	GLI-Kruppel family member GLI2	0.180
Hesx1	homeobox gene expressed in ES cells	0.175
Otx1	orthodenticle homolog 1 (Drosophila)	0.171
Neurod4	neurogenic differentiation 4	0.167	Mouse
Dll4	delta-like 4 (Drosophila)	0.155
Vangl2	vang-like 2 (van gogh, Drosophila)	0.140
Apc	adenomatosis polyposis coli	0.137
Lef1	lymphoid enhancer binding factor 1	0.137
Ntf3	neurotrophin 3	0.133
She	src homology 2 domain-containing transforming protein E	0.132
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.128
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.126
Efna2	ephrin A2	0.126
Tlx3	T-cell leukemia, homeobox 3	0.119
Hes5	hairy and enhancer of split 5 (Drosophila)	0.118	Mouse
Pten	phosphatase and tensin homolog	0.117
Gata6	GATA binding protein 6	0.111
Ptf1a	pancreas specific transcription factor, 1a	0.110	Mouse
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.109	Mouse
Wnt3a	wingless-related MMTV integration site 3A	0.103
Rarb	retinoic acid receptor, beta	0.102
Axin1	axin 1	0.102
Sall4	sal-like 4 (Drosophila)	0.101
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.098	Mouse
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.097
Gdf5	growth differentiation factor 5	0.097	Mouse
Dll1	delta-like 1 (Drosophila)	0.097
Alx3	aristaless-like homeobox 3	0.097
Insm1	insulinoma-associated 1	0.097
Sox11	SRY-box containing gene 11	0.096	Mouse
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.093
Nos3	nitric oxide synthase 3, endothelial cell	0.093
Foxf1a	forkhead box F1a	0.091
Hoxd12	homeobox D12	0.090
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.089
Fgf3	fibroblast growth factor 3	0.088
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.086
Fgf10	fibroblast growth factor 10	0.084
Hoxd3	homeobox D3	0.084
Hoxd11	homeobox D11	0.084
Hoxa2	homeobox A2	0.083
Lhx3	LIM homeobox protein 3	0.082	Mouse
Gas1	growth arrest specific 1	0.081
Meox2	mesenchyme homeobox 2	0.081
Tbx4	T-box 4	0.078	Mouse
Uncx	UNC homeobox	0.076
Lhx9	LIM homeobox protein 9	0.076	Mouse
Tcfap2c	transcription factor AP-2, gamma	0.074
Pou3f3	POU domain, class 3, transcription factor 3	0.071
Hoxa10	homeobox A10	0.071
Tbx15	T-box 15	0.069	Mouse
Pou4f3	POU domain, class 4, transcription factor 3	0.069
Lrp2	low density lipoprotein receptor-related protein 2	0.067	Mouse
Hmx1	H6 homeobox 1	0.067
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.067
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.066
Lrp6	low density lipoprotein receptor-related protein 6	0.063
Bnc1	basonuclin 1	0.062
Smad4	MAD homolog 4 (Drosophila)	0.061
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.061
Fgf15	fibroblast growth factor 15	0.061
Pitx3	paired-like homeodomain transcription factor 3	0.058	Mouse
Hoxb3	homeobox B3	0.056
Dlx1	distal-less homeobox 1	0.055
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.053
Gpc3	glypican 3	0.053
Mecom	MDS1 and EVI1 complex locus	0.052
Acvr1	activin A receptor, type 1	0.050
Col22a1	collagen, type XXII, alpha 1	0.050
Evx1	even skipped homeotic gene 1 homolog	0.049
Pax9	paired box gene 9	0.049
Hoxb1	homeobox B1	0.049
Btbd17	BTB (POZ) domain containing 17	0.048
Sox17	SRY-box containing gene 17	0.047	Mouse
Nf1	neurofibromatosis 1	0.047
Hoxa4	homeobox A4	0.046
Tal2	T-cell acute lymphocytic leukemia 2	0.045	Mouse
Kiss1	KiSS-1 metastasis-suppressor	0.045
Bcl2	B-cell leukemia/lymphoma 2	0.045
Tgfb2	transforming growth factor, beta 2	0.044
Edar	ectodysplasin-A receptor	0.044
Hoxa5	homeobox A5	0.043
Npr3	natriuretic peptide receptor 3	0.042
Hoxb4	homeobox B4	0.040
Cdx2	caudal type homeobox 2	0.040
Pou3f4	POU domain, class 3, transcription factor 4	0.039
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.039
Ptk7	PTK7 protein tyrosine kinase 7	0.039
Neurod1	neurogenic differentiation 1	0.039	Mouse
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.038
Phox2b	paired-like homeobox 2b	0.038
Prrx2	paired related homeobox 2	0.037
Hoxc4	homeobox C4	0.037
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.037
Gdf6	growth differentiation factor 6	0.037	Mouse
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.036
Notch3	Notch gene homolog 3 (Drosophila)	0.036
Wnt1	wingless-related MMTV integration site 1	0.035
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.035
Pax8	paired box gene 8	0.034
Gata2	GATA binding protein 2	0.034
Pou4f2	POU domain, class 4, transcription factor 2	0.034
Sox13	SRY-box containing gene 13	0.033
Gdnf	glial cell line derived neurotrophic factor	0.033
Hoxa3	homeobox A3	0.033
Wnt11	wingless-related MMTV integration site 11	0.032
Efnb2	ephrin B2	0.032
Cer1	cerberus 1 homolog (Xenopus laevis)	0.031
Foxh1	forkhead box H1	0.031
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.030
Hoxd1	homeobox D1	0.030
Lhx4	LIM homeobox protein 4	0.030	Mouse
Rxra	retinoid X receptor alpha	0.030
Lhx5	LIM homeobox protein 5	0.030	Mouse
Gata1	GATA binding protein 1	0.030
Tcf21	transcription factor 21	0.029
Sim1	single-minded homolog 1 (Drosophila)	0.028
Meox1	mesenchyme homeobox 1	0.028
Hoxd4	homeobox D4	0.028
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.028
Hoxb6	homeobox B6	0.028
Trp63	transformation related protein 63	0.028
Fzd2	frizzled homolog 2 (Drosophila)	0.028
Pou5f1	POU domain, class 5, transcription factor 1	0.028
Dlx2	distal-less homeobox 2	0.027
Tead4	TEA domain family member 4	0.027
Cxadr	coxsackie virus and adenovirus receptor	0.027
Ebf3	early B-cell factor 3	0.026
Neurog3	neurogenin 3	0.026	Mouse
Zfp503	zinc finger protein 503	0.026
Bdnf	brain derived neurotrophic factor	0.026
Dlx6	distal-less homeobox 6	0.025
Fzd8	frizzled homolog 8 (Drosophila)	0.024
Srrm4	serine/arginine repetitive matrix 4	0.024
Dlx5	distal-less homeobox 5	0.024
Myf5	myogenic factor 5	0.024
Dmbx1	diencephalon/mesencephalon homeobox 1	0.024
Sox7	SRY-box containing gene 7	0.023	Mouse
En2	engrailed 2	0.023
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.023
Gdf3	growth differentiation factor 3	0.023
Pkd1	polycystic kidney disease 1 homolog	0.023
Vax1	ventral anterior homeobox containing gene 1	0.023
Barx1	BarH-like homeobox 1	0.023
Irx3	Iroquois related homeobox 3 (Drosophila)	0.023
Twist1	twist homolog 1 (Drosophila)	0.023	Mouse
Dab1	disabled homolog 1 (Drosophila)	0.023
Arx	aristaless related homeobox	0.023
Tal1	T-cell acute lymphocytic leukemia 1	0.023	Mouse
Nkx2-1	NK2 homeobox 1	0.023
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.023
Tenc1	tensin like C1 domain-containing phosphatase	0.023
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.022
Foxa2	forkhead box A2	0.022
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.022
Rara	retinoic acid receptor, alpha	0.022
Hmga2	high mobility group AT-hook 2	0.022
Wnt6	wingless-related MMTV integration site 6	0.022
Zic1	zinc finger protein of the cerebellum 1	0.022
Pthlh	parathyroid hormone-like peptide	0.022
Erbb2ip	Erbb2 interacting protein	0.022
Efnb1	ephrin B1	0.022
Axin2	axin2	0.021
Sall3	sal-like 3 (Drosophila)	0.021
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.021
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.021
T	brachyury	0.021	Mouse
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.020
Hmx3	H6 homeobox 3	0.020
Sox3	SRY-box containing gene 3	0.020	Mouse
Fgf17	fibroblast growth factor 17	0.020
Col13a1	collagen, type XIII, alpha 1	0.020
Sox1	SRY-box containing gene 1	0.020
Pofut1	protein O-fucosyltransferase 1	0.020
Eya4	eyes absent 4 homolog (Drosophila)	0.019	Mouse
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.019
Ighmbp2	immunoglobulin mu binding protein 2	0.019
Tead2	TEA domain family member 2	0.018
Art5	ADP-ribosyltransferase 5	0.018
Gja3	gap junction protein, alpha 3	0.018
Notch2	Notch gene homolog 2 (Drosophila)	0.018
Kdr	kinase insert domain protein receptor	0.018
Emid2	EMI domain containing 2	0.018
Alx4	aristaless-like homeobox 4	0.018
Efna4	ephrin A4	0.018
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.018
Onecut1	one cut domain, family member 1	0.018
Ptch1	patched homolog 1	0.017
Padi3	peptidyl arginine deiminase, type III	0.017
Yap1	yes-associated protein 1	0.017
Dach1	dachshund 1 (Drosophila)	0.017
Gli1	GLI-Kruppel family member GLI1	0.017
Mmp24	matrix metallopeptidase 24	0.017
Col2a1	collagen, type II, alpha 1	0.017
Fgf18	fibroblast growth factor 18	0.017
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.017
Pkdcc	protein kinase domain containing, cytoplasmic	0.016
Msi1	Musashi homolog 1(Drosophila)	0.016
Sox21	SRY-box containing gene 21	0.016
Hoxd10	homeobox D10	0.016
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.016
Hoxd9	homeobox D9	0.016
Pcdh12	protocadherin 12	0.016
Ssbp3	single-stranded DNA binding protein 3	0.016
Shox2	short stature homeobox 2	0.015
Dlk1	delta-like 1 homolog (Drosophila)	0.015
Sox18	SRY-box containing gene 18	0.015	Mouse
Gata5	GATA binding protein 5	0.015
Ptprb	protein tyrosine phosphatase, receptor type, B	0.015
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.015
Bmp5	bone morphogenetic protein 5	0.015	Mouse
Tbx5	T-box 5	0.015
Hes3	hairy and enhancer of split 3 (Drosophila)	0.015	Mouse
Fbn2	fibrillin 2	0.015
Tbx6	T-box 6	0.015	Mouse
Hoxb7	homeobox B7	0.015
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.015
Gdf11	growth differentiation factor 11	0.015
Hhex	hematopoietically expressed homeobox	0.015
Cldn6	claudin 6	0.015
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.015
Peg10	paternally expressed 10	0.014
Tgfbr2	transforming growth factor, beta receptor II	0.014
Zbtb46	zinc finger and BTB domain containing 46	0.014
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.014
Hoxb9	homeobox B9	0.014
Lmx1b	LIM homeobox transcription factor 1 beta	0.014	Mouse
Fgd5	FYVE, RhoGEF and PH domain containing 5	0.014
Fhl3	four and a half LIM domains 3	0.014
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.014
Tead3	TEA domain family member 3	0.014
Pou3f2	POU domain, class 3, transcription factor 2	0.014
Htt	huntingtin	0.014
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.013	Mouse
Aplnr	apelin receptor	0.013
Sharpin	SHANK-associated RH domain interacting protein	0.013
Fgf9	fibroblast growth factor 9	0.013
Prop1	paired like homeodomain factor 1	0.013
Twist2	twist homolog 2 (Drosophila)	0.013	Mouse
Rnf111	ring finger 111	0.013
Foxb1	forkhead box B1	0.013
Eda	ectodysplasin-A	0.013
Myoz1	myozenin 1	0.013
Hif3a	hypoxia inducible factor 3, alpha subunit	0.013
Rspo1	R-spondin homolog (Xenopus laevis)	0.013
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.013
Gpr50	G-protein-coupled receptor 50	0.013
Esrrb	estrogen related receptor, beta	0.013
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.013
Robo3	roundabout homolog 3 (Drosophila)	0.013
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.012
Myog	myogenin	0.012
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.012
Hoxa9	homeobox A9	0.012
Irs3	insulin receptor substrate 3	0.012
Tulp1	tubby like protein 1	0.012
Cited1	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1	0.012
Tgfa	transforming growth factor alpha	0.012
Hoxb13	homeobox B13	0.012
Dmpk	dystrophia myotonica-protein kinase	0.012
Sim2	single-minded homolog 2 (Drosophila)	0.012
Lama5	laminin, alpha 5	0.012
Ret	ret proto-oncogene	0.012
Foxd3	forkhead box D3	0.012
Cilp2	cartilage intermediate layer protein 2	0.012
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.012
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.012
Tek	endothelial-specific receptor tyrosine kinase	0.012
Tcfap2b	transcription factor AP-2 beta	0.012
Tcf15	transcription factor 15	0.012	Mouse
Foxd1	forkhead box D1	0.012
Homer3	homer homolog 3 (Drosophila)	0.012
Smad2	MAD homolog 2 (Drosophila)	0.012	Mouse
Wnt5a	wingless-related MMTV integration site 5A	0.012
Msx3	homeobox, msh-like 3	0.012
Zfp362	zinc finger protein 362	0.011
Edn3	endothelin 3	0.011
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.011
Hoxc6	homeobox C6	0.011
Smad7	MAD homolog 7 (Drosophila)	0.011	Mouse
Crb2	crumbs homolog 2 (Drosophila)	0.011
Insm2	insulinoma-associated 2	0.011
Osr1	odd-skipped related 1 (Drosophila)	0.011
Neurog1	neurogenin 1	0.011	Mouse
Foxd2	forkhead box D2	0.011
Tcfcp2l1	transcription factor CP2-like 1	0.011
Fgf4	fibroblast growth factor 4	0.011
Wnt2b	wingless related MMTV integration site 2b	0.011
Efs	embryonal Fyn-associated substrate	0.011
Btn1a1	butyrophilin, subfamily 1, member A1	0.011
Sfrp2	secreted frizzled-related protein 2	0.011
Psen1	presenilin 1	0.011
Sox9	SRY-box containing gene 9	0.011
Adcy4	adenylate cyclase 4	0.011
Rasip1	Ras interacting protein 1	0.011
Gast	gastrin	0.010
Wnt4	wingless-related MMTV integration site 4	0.010
Pou3f1	POU domain, class 3, transcription factor 1	0.010
Fzd6	frizzled homolog 6 (Drosophila)	0.010
Grem1	gremlin 1	0.010
Sox4	SRY-box containing gene 4	0.010	Mouse
Atoh7	atonal homolog 7 (Drosophila)	0.010	Mouse
Bmp6	bone morphogenetic protein 6	0.010	Mouse
Hoxb5	homeobox B5	0.010
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.010
Wnt3	wingless-related MMTV integration site 3	0.010
Gsk3b	glycogen synthase kinase 3 beta	0.010
Stc2	stanniocalcin 2	0.010
Hoxc8	homeobox C8	0.010