Mus musculus

40 known processes

Mks1

Meckel syndrome, type 1

(Aliases: B8d3,AK190930)

Mks1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium morphogenesis GO:0060271 102 1.000
cilium assembly GO:0042384 81 1.000
smoothened signaling pathway GO:0007224 105 1.000
cellular component assembly involved in morphogenesis GO:0010927 139 1.000
nonmotile primary cilium assembly GO:0035058 8 0.999
regionalization GO:0003002 337 0.997
organelle assembly GO:0070925 177 0.991
neural tube development GO:0021915 160 0.989
embryonic organ morphogenesis GO:0048562 276 0.989
regulation of cilium assembly GO:1902017 7 0.988
kidney development GO:0001822 213 0.984
epithelial tube morphogenesis GO:0060562 303 0.984
renal system development GO:0072001 225 0.983
embryonic heart tube development GO:0035050 65 0.963
determination of heart left right asymmetry GO:0061371 48 0.962
floor plate morphogenesis GO:0033505 3 0.949
appendage morphogenesis GO:0035107 149 0.930
epithelial tube formation GO:0072175 130 0.927
embryonic digit morphogenesis GO:0042733 56 0.917
determination of left right symmetry GO:0007368 80 0.906
limb morphogenesis GO:0035108 149 0.903
nephron development GO:0072006 109 0.893
neural tube formation GO:0001841 108 0.886
embryonic heart tube morphogenesis GO:0003143 51 0.881
kidney morphogenesis GO:0060993 83 0.881
spinal cord development GO:0021510 81 0.875
heart morphogenesis GO:0003007 178 0.870
embryonic limb morphogenesis GO:0030326 126 0.863
neural tube closure GO:0001843 90 0.862
embryonic appendage morphogenesis GO:0035113 126 0.848
dorsal ventral neural tube patterning GO:0021904 28 0.841
regulation of smoothened signaling pathway GO:0008589 58 0.836
axial mesodermal cell fate commitment GO:0048322 1 0.813
morphogenesis of embryonic epithelium GO:0016331 159 0.800
urogenital system development GO:0001655 261 0.789
left right pattern formation GO:0060972 23 0.754
morphogenesis of a polarized epithelium GO:0001738 37 0.744
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 12 0.728
digestive tract morphogenesis GO:0048546 147 0.718
forebrain development GO:0030900 302 0.691
planar dichotomous subdivision of terminal units involved in lung branching morphogenesis GO:0060489 2 0.682
camera type eye development GO:0043010 266 0.662
kidney epithelium development GO:0072073 121 0.659
limb development GO:0060173 166 0.650
telencephalon development GO:0021537 186 0.616
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.605
spinal cord motor neuron differentiation GO:0021522 35 0.597
appendage development GO:0048736 166 0.597
protein localization to organelle GO:0033365 185 0.581
dna metabolic process GO:0006259 303 0.576
lung development GO:0030324 164 0.555
planar cell polarity pathway involved in axis elongation GO:0003402 4 0.552
liver development GO:0001889 66 0.547
nephron epithelium development GO:0072009 92 0.544
neural tube patterning GO:0021532 43 0.532
primary neural tube formation GO:0014020 95 0.488
epidermis development GO:0008544 187 0.471
floor plate formation GO:0021508 2 0.471
digestive system development GO:0055123 200 0.461
pronephric nephron development GO:0039019 1 0.436
axial mesodermal cell fate specification GO:0048327 1 0.436
embryonic epithelial tube formation GO:0001838 130 0.407
renal tubule development GO:0061326 87 0.387
skin development GO:0043588 220 0.379
digestive tract development GO:0048565 190 0.361
nephron tubule morphogenesis GO:0072078 68 0.360
pronephros morphogenesis GO:0072114 1 0.329
regulation of organ morphogenesis GO:2000027 144 0.327
central nervous system neuron axonogenesis GO:0021955 28 0.325
embryonic heart tube left right pattern formation GO:0060971 5 0.320
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.317
inner ear receptor stereocilium organization GO:0060122 23 0.314
gastrulation GO:0007369 116 0.297
epidermal stem cell homeostasis GO:0036334 2 0.296
regulation of intracellular transport GO:0032386 159 0.293
microtubule based process GO:0007017 236 0.274
negative regulation of calcium ion transmembrane transporter activity GO:1901020 1 0.274
sensory perception of sour taste GO:0050915 2 0.263
detection of nodal flow GO:0003127 2 0.255
regulation of protein localization GO:0032880 231 0.251
epithelial cilium movement GO:0003351 12 0.248
tube formation GO:0035148 140 0.241
hepaticobiliary system development GO:0061008 67 0.240
pronephros development GO:0048793 5 0.238
establishment or maintenance of cell polarity GO:0007163 86 0.225
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.224
nephron tubule development GO:0072080 84 0.223
positive regulation of receptor internalization GO:0002092 4 0.221
negative regulation of ryanodine sensitive calcium release channel activity GO:0060315 1 0.219
gland development GO:0048732 330 0.216
renal tubule morphogenesis GO:0061333 72 0.216
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.211
regulation of microtubule based process GO:0032886 52 0.207
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.205
protein targeting GO:0006605 143 0.202
lateral sprouting involved in lung morphogenesis GO:0060490 2 0.201
regulation of autophagic vacuole assembly GO:2000785 4 0.199
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.198
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity GO:0031585 2 0.197
axial mesoderm development GO:0048318 8 0.187
mesonephric epithelium development GO:0072163 94 0.187
regulation of spindle organization GO:0090224 2 0.185
nephron morphogenesis GO:0072028 69 0.183
determination of digestive tract left right asymmetry GO:0071907 1 0.182
metanephric ascending thin limb development GO:0072218 2 0.177
establishment of protein localization to organelle GO:0072594 118 0.176
sensory organ morphogenesis GO:0090596 242 0.174
axial mesoderm formation GO:0048320 3 0.174
ear development GO:0043583 200 0.174
regulation of protein transport GO:0051223 163 0.173
regulation of cytoplasmic transport GO:1903649 112 0.170
nuclear transport GO:0051169 139 0.170
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.170
photoreceptor cell differentiation GO:0046530 52 0.163
formation of radial glial scaffolds GO:0021943 4 0.161
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000162 1 0.160
negative regulation of cation channel activity GO:2001258 1 0.159
metanephros morphogenesis GO:0003338 24 0.156
somite specification GO:0001757 4 0.153
proximal convoluted tubule development GO:0072019 1 0.145
respiratory tube development GO:0030323 167 0.143
intraciliary retrograde transport GO:0035721 3 0.139
neuroepithelial cell differentiation GO:0060563 37 0.137
cellular response to acidic ph GO:0071468 4 0.130
gonad development GO:0008406 141 0.129
microtubule cytoskeleton organization GO:0000226 157 0.128
left lung morphogenesis GO:0060460 3 0.126
protein import into nucleus GO:0006606 95 0.125
canonical wnt signaling pathway GO:0060070 130 0.120
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.119
retina homeostasis GO:0001895 23 0.119
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.116
respiratory system development GO:0060541 190 0.115
axoneme assembly GO:0035082 15 0.115
central nervous system neuron differentiation GO:0021953 162 0.114
embryonic skeletal system development GO:0048706 120 0.114
retina morphogenesis in camera type eye GO:0060042 45 0.113
inner ear receptor cell development GO:0060119 39 0.109
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.108
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.107
inorganic cation transmembrane transport GO:0098662 207 0.107
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.107
cardiac septum morphogenesis GO:0060411 46 0.106
morphogenesis of a branching structure GO:0001763 203 0.103
branching morphogenesis of an epithelial tube GO:0048754 159 0.102
mitochondrion organization GO:0007005 134 0.102
vesicle localization GO:0051648 86 0.099
reactive nitrogen species metabolic process GO:2001057 0 0.098
cellular protein catabolic process GO:0044257 155 0.097
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.096
regulation of kinase activity GO:0043549 249 0.096
regulation of protein targeting GO:1903533 61 0.095
muscular septum morphogenesis GO:0003150 4 0.094
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.094
hindbrain development GO:0030902 128 0.092
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.092
mechanoreceptor differentiation GO:0042490 67 0.091
fertilization GO:0009566 127 0.091
regulation of protein import into nucleus GO:0042306 52 0.090
positive regulation of transferase activity GO:0051347 167 0.090
purine nucleotide metabolic process GO:0006163 302 0.088
membranous septum morphogenesis GO:0003149 6 0.088
regulation of wnt signaling pathway GO:0030111 123 0.086
autophagic vacuole assembly GO:0000045 13 0.084
inner ear receptor cell differentiation GO:0060113 61 0.083
negative regulation of cellular component organization GO:0051129 194 0.083
lateral ventricle development GO:0021670 11 0.080
microtubule based transport GO:0010970 50 0.079
regulation of protein kinase activity GO:0045859 232 0.079
vacuole organization GO:0007033 38 0.079
left lung development GO:0060459 4 0.079
forebrain radial glial cell differentiation GO:0021861 4 0.078
axial mesodermal cell differentiation GO:0048321 1 0.078
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.077
axis elongation involved in somitogenesis GO:0090245 4 0.077
ascending thin limb development GO:0072021 2 0.076
nephron epithelium morphogenesis GO:0072088 68 0.076
regulation of cellular catabolic process GO:0031329 242 0.076
intracellular protein transport GO:0006886 204 0.074
negative regulation of cell proliferation GO:0008285 296 0.074
cardiac septum development GO:0003279 59 0.074
positive regulation of intracellular protein transport GO:0090316 42 0.073
response to sterol GO:0036314 4 0.073
ventral spinal cord development GO:0021517 48 0.072
cellular response to cholesterol GO:0071397 2 0.072
regulation of establishment of protein localization GO:0070201 181 0.072
determination of left right asymmetry in nervous system GO:0035545 1 0.071
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.071
ventral midline development GO:0007418 4 0.071
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.071
negative regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000160 1 0.070
hair follicle development GO:0001942 85 0.070
spermatogenesis GO:0007283 284 0.070
left right axis specification GO:0070986 13 0.069
somatic motor neuron differentiation GO:0021523 6 0.069
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.069
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.069
metanephric part of ureteric bud development GO:0035502 2 0.068
positive regulation of kinase activity GO:0033674 155 0.068
notochord formation GO:0014028 5 0.068
inorganic ion transmembrane transport GO:0098660 234 0.068
mesonephric tubule development GO:0072164 94 0.067
regulation of cell cycle process GO:0010564 160 0.067
metencephalon development GO:0022037 89 0.067
protein localization to nucleus GO:0034504 121 0.067
positive regulation of protein localization to nucleus GO:1900182 30 0.067
negative regulation of calcium ion transmembrane transport GO:1903170 1 0.066
regulation of mapk cascade GO:0043408 248 0.066
photoreceptor cell outer segment organization GO:0035845 5 0.066
protein refolding GO:0042026 1 0.066
nucleoside phosphate metabolic process GO:0006753 338 0.066
establishment of organelle localization GO:0051656 122 0.065
dendrite self avoidance GO:0070593 2 0.065
single organism nuclear import GO:1902593 95 0.065
single fertilization GO:0007338 82 0.065
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.064
skeletal system development GO:0001501 356 0.063
regulation of epithelial cell proliferation GO:0050678 141 0.063
dichotomous subdivision of terminal units involved in lung branching GO:0060448 3 0.063
photoreceptor cell development GO:0042461 40 0.062
regulation of fat cell differentiation GO:0045598 81 0.060
epithelial tube branching involved in lung morphogenesis GO:0060441 28 0.060
actin cytoskeleton organization GO:0030036 220 0.060
cardiac muscle cell differentiation GO:0055007 69 0.060
transmembrane transport GO:0055085 412 0.059
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000149 1 0.059
negative regulation of lymphocyte activation GO:0051250 91 0.057
cellular response to fluid shear stress GO:0071498 4 0.057
intraciliary transport GO:0042073 9 0.057
cardiac muscle tissue development GO:0048738 130 0.056
cerebellum development GO:0021549 77 0.055
dna repair GO:0006281 107 0.055
cellular response to dna damage stimulus GO:0006974 207 0.055
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.055
negative regulation of mitotic cell cycle GO:0045930 58 0.054
cardiac chamber morphogenesis GO:0003206 93 0.054
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.054
regulation of canonical wnt signaling pathway GO:0060828 82 0.053
regulation of transferase activity GO:0051338 263 0.053
regulation of nucleocytoplasmic transport GO:0046822 73 0.053
glomerulus development GO:0032835 40 0.052
small gtpase mediated signal transduction GO:0007264 97 0.052
skeletal muscle organ development GO:0060538 163 0.052
molting cycle GO:0042303 90 0.052
neural plate development GO:0001840 12 0.051
cilium movement GO:0003341 28 0.051
positive regulation of nervous system development GO:0051962 221 0.051
midgut development GO:0007494 4 0.051
reactive oxygen species metabolic process GO:0072593 84 0.051
positive regulation of protein modification process GO:0031401 299 0.051
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.051
purine containing compound metabolic process GO:0072521 311 0.050
thermosensory behavior GO:0040040 1 0.050
regulation of establishment of planar polarity GO:0090175 28 0.049
cellular macromolecule catabolic process GO:0044265 206 0.049
positive regulation of protein phosphorylation GO:0001934 242 0.049
cardiocyte differentiation GO:0035051 87 0.049
epithelial cell proliferation GO:0050673 174 0.048
metanephric loop of henle development GO:0072236 4 0.048
lung morphogenesis GO:0060425 50 0.048
regulation of cardioblast differentiation GO:0051890 3 0.048
cardiac ventricle development GO:0003231 83 0.048
positive regulation of hydrolase activity GO:0051345 148 0.047
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.047
cloaca development GO:0035844 3 0.047
cell migration involved in gastrulation GO:0042074 13 0.047
ventricular system development GO:0021591 27 0.047
otic vesicle development GO:0071599 14 0.046
cytoplasmic transport GO:0016482 234 0.046
positive regulation of protein kinase activity GO:0045860 144 0.046
protein import GO:0017038 101 0.045
positive regulation of intracellular transport GO:0032388 70 0.045
single organismal cell cell adhesion GO:0016337 131 0.045
pancreas development GO:0031016 57 0.045
central nervous system neuron development GO:0021954 67 0.045
cardiac chamber development GO:0003205 108 0.045
multicellular organismal homeostasis GO:0048871 164 0.045
regulation of cellular component biogenesis GO:0044087 181 0.043
oocyte construction GO:0007308 2 0.043
regulation of epidermal cell differentiation GO:0045604 21 0.043
negative regulation of t cell activation GO:0050868 65 0.043
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.043
positive regulation of immature t cell proliferation GO:0033091 4 0.043
canonical wnt signaling pathway involved in neural crest cell differentiation GO:0044335 1 0.042
notochord cell differentiation GO:0060034 1 0.042
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.042
stem cell development GO:0048864 219 0.041
protein export from nucleus GO:0006611 20 0.041
epithelial cell morphogenesis GO:0003382 41 0.041
heart formation GO:0060914 16 0.041
cell fate commitment GO:0045165 210 0.041
cellular ketone metabolic process GO:0042180 84 0.040
receptor mediated endocytosis GO:0006898 51 0.040
negative regulation of molecular function GO:0044092 258 0.040
regulation of transporter activity GO:0032409 57 0.040
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.039
mitotic cell cycle GO:0000278 195 0.039
negative regulation of mesodermal cell fate specification GO:0042662 3 0.039
retina layer formation GO:0010842 16 0.039
mesenchyme development GO:0060485 152 0.039
cation transmembrane transport GO:0098655 266 0.039
pallium development GO:0021543 120 0.039
nuclear import GO:0051170 95 0.038
regulation of membrane potential GO:0042391 192 0.038
dna replication GO:0006260 52 0.038
ureteric bud development GO:0001657 94 0.038
positive regulation of cytoplasmic transport GO:1903651 40 0.038
endodermal cell fate specification GO:0001714 4 0.038
positive regulation of cell death GO:0010942 224 0.037
cell migration involved in kidney development GO:0035787 3 0.037
spinal cord dorsal ventral patterning GO:0021513 23 0.037
regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000161 1 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
regulation of homeostatic process GO:0032844 182 0.036
regulation of protein localization to nucleus GO:1900180 60 0.036
blood circulation GO:0008015 195 0.036
negative regulation of cell cycle process GO:0010948 69 0.035
reactive oxygen species biosynthetic process GO:1903409 8 0.035
wnt signaling pathway GO:0016055 188 0.035
determination of left right asymmetry in lateral mesoderm GO:0003140 5 0.035
nucleocytoplasmic transport GO:0006913 139 0.035
cell proliferation in hindbrain GO:0021534 10 0.035
spinal cord patterning GO:0021511 25 0.035
retina development in camera type eye GO:0060041 119 0.035
negative regulation of leukocyte proliferation GO:0070664 46 0.035
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.034
negative regulation of organelle organization GO:0010639 90 0.034
canonical wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation GO:0061324 2 0.034
multi multicellular organism process GO:0044706 109 0.034
cardiac muscle cell development GO:0055013 39 0.034
organelle localization GO:0051640 179 0.034
mapk cascade GO:0000165 281 0.033
establishment of vesicle localization GO:0051650 81 0.033
protein targeting to mitochondrion GO:0006626 6 0.033
positive regulation of smoothened signaling pathway GO:0045880 23 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.033
regulation of reactive oxygen species metabolic process GO:2000377 40 0.033
lymphocyte proliferation GO:0046651 164 0.033
mesodermal cell differentiation GO:0048333 22 0.033
negative regulation of planar cell polarity pathway involved in neural tube closure GO:2000168 1 0.033
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.032
response to ph GO:0009268 14 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.032
embryonic skeletal joint morphogenesis GO:0060272 11 0.032
negative regulation of immature t cell proliferation GO:0033087 3 0.032
positive regulation of protein transport GO:0051222 93 0.032
specification of organ identity GO:0010092 30 0.032
regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000159 1 0.032
nucleotide metabolic process GO:0009117 332 0.032
tube closure GO:0060606 91 0.032
regulation of endodermal cell fate specification GO:0042663 2 0.032
vesicle targeting GO:0006903 6 0.032
rho protein signal transduction GO:0007266 32 0.031
hair cycle GO:0042633 90 0.031
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.031
negative regulation of wnt signaling pathway GO:0030178 73 0.031
glomerulus morphogenesis GO:0072102 10 0.031
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.031
establishment of spindle orientation GO:0051294 15 0.031
endocytosis GO:0006897 168 0.031
smoothened signaling pathway involved in ventral spinal cord patterning GO:0021910 7 0.031
cardiac muscle tissue morphogenesis GO:0055008 44 0.030
brain morphogenesis GO:0048854 32 0.030
regulation of planar cell polarity pathway involved in neural tube closure GO:2000167 1 0.030
sensory perception of chemical stimulus GO:0007606 51 0.030
negative regulation of cell cycle phase transition GO:1901988 48 0.030
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 6 0.029
regulation of secretion by cell GO:1903530 249 0.029
ventricular septum morphogenesis GO:0060412 27 0.029
t cell differentiation in thymus GO:0033077 77 0.029
regulation of t cell proliferation GO:0042129 92 0.028
chronological cell aging GO:0001300 1 0.028
establishment of monopolar cell polarity GO:0061162 8 0.028
calcium ion transmembrane transport GO:0070588 85 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
muscle system process GO:0003012 141 0.028
intermediate filament cytoskeleton organization GO:0045104 26 0.028
regulation of organelle organization GO:0033043 289 0.028
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.028
mesoderm structural organization GO:0048338 1 0.028
regulation of nucleotide metabolic process GO:0006140 169 0.028
regulation of mitotic cell cycle GO:0007346 126 0.028
atp metabolic process GO:0046034 75 0.028
autophagy GO:0006914 45 0.028
forelimb morphogenesis GO:0035136 40 0.028
establishment of protein localization to mitochondrion GO:0072655 11 0.027
canonical wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development GO:0061310 1 0.027
metanephros development GO:0001656 79 0.027
trophectodermal cellular morphogenesis GO:0001831 3 0.027
negative regulation of transposition GO:0010529 2 0.027
negative regulation of t cell differentiation GO:0045581 23 0.027
inner ear morphogenesis GO:0042472 101 0.027
embryonic neurocranium morphogenesis GO:0048702 3 0.027
regulation of binding GO:0051098 111 0.026
intracellular sterol transport GO:0032366 3 0.026
prechordal plate formation GO:0021501 1 0.026
camp metabolic process GO:0046058 40 0.026
negative regulation of neuron death GO:1901215 98 0.026
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.026
calcium ion transport GO:0006816 159 0.026
cellular response to sterol GO:0036315 2 0.026
neuronal action potential GO:0019228 54 0.026
carbohydrate metabolic process GO:0005975 230 0.026
mating GO:0007618 27 0.026
placenta development GO:0001890 140 0.026
positive regulation of apoptotic process GO:0043065 217 0.026
embryonic placenta development GO:0001892 98 0.026
cellular response to lipid GO:0071396 145 0.025
regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:2000150 1 0.025
positive regulation of transmembrane transport GO:0034764 29 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
negative regulation of t cell proliferation GO:0042130 38 0.025
regulation of intracellular protein transport GO:0033157 82 0.025
cardiac cell fate specification GO:0060912 2 0.025
positive regulation of protein import into nucleus GO:0042307 26 0.025
response to fluid shear stress GO:0034405 7 0.025
roof plate formation GO:0021509 1 0.025
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.025
skeletal muscle thin filament assembly GO:0030240 2 0.024
epithelial cell development GO:0002064 159 0.024
male gamete generation GO:0048232 285 0.024
regulation of ryanodine sensitive calcium release channel activity GO:0060314 10 0.024
regulation of leukocyte mediated immunity GO:0002703 104 0.024
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.024
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.024
negative regulation of stem cell maintenance GO:1902455 4 0.024
diencephalon development GO:0021536 63 0.024
heart contraction GO:0060047 93 0.024
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.024
regulation of protein binding GO:0043393 60 0.024
establishment of planar polarity GO:0001736 28 0.024
exocytosis GO:0006887 121 0.024
regulation of protein serine threonine kinase activity GO:0071900 157 0.023
multicellular organismal reproductive behavior GO:0033057 23 0.023
anatomical structure homeostasis GO:0060249 145 0.023
tissue homeostasis GO:0001894 115 0.023
branching involved in ureteric bud morphogenesis GO:0001658 56 0.023
regulation of cardiac chamber morphogenesis GO:1901219 2 0.023
trachea formation GO:0060440 3 0.023
smooth muscle tissue development GO:0048745 22 0.023
sulfur compound metabolic process GO:0006790 100 0.023
odontogenesis of dentin containing tooth GO:0042475 66 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.022
regulation of cytoskeleton organization GO:0051493 122 0.022
negative regulation of heart looping GO:1901208 1 0.022
negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:2000151 1 0.022
regulation of cell cycle GO:0051726 281 0.022
axonogenesis GO:0007409 274 0.022
keratinocyte development GO:0003334 10 0.022
positive regulation of mapk cascade GO:0043410 170 0.022
tendon formation GO:0035992 4 0.022
transforming growth factor beta receptor signaling pathway involved in primitive streak formation GO:0090010 1 0.022
neural crest formation GO:0014029 2 0.022
endodermal digestive tract morphogenesis GO:0061031 4 0.021
regulation of protein catabolic process GO:0042176 108 0.021
endoderm development GO:0007492 45 0.021
regulation of cation channel activity GO:2001257 22 0.021
fasciculation of sensory neuron axon GO:0097155 3 0.021
muscle cell differentiation GO:0042692 261 0.021
mitotic cell cycle process GO:1903047 159 0.021
kidney smooth muscle tissue development GO:0072194 3 0.021
spermatid differentiation GO:0048515 115 0.021
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000164 1 0.021
negative regulation of epithelial cell proliferation GO:0050680 64 0.021
response to interleukin 4 GO:0070670 23 0.021
cochlea development GO:0090102 35 0.021
nephric duct morphogenesis GO:0072178 7 0.021
cellular response to organic cyclic compound GO:0071407 87 0.021
regulation of vacuole organization GO:0044088 4 0.021
negative regulation of cell cycle GO:0045786 123 0.020
positive regulation of transcription by glucose GO:0046016 3 0.020
mesonephros development GO:0001823 97 0.020
oocyte axis specification GO:0007309 2 0.020
regulation of cell proliferation involved in outflow tract morphogenesis GO:1901963 2 0.020
neuron migration GO:0001764 122 0.020
iris morphogenesis GO:0061072 2 0.020
regulation of lymphocyte differentiation GO:0045619 107 0.020
spindle organization GO:0007051 28 0.020
ureteric bud morphogenesis GO:0060675 62 0.020
regulation of glomerular mesangial cell proliferation GO:0072124 1 0.020
negative regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060829 1 0.020
positive regulation of wnt signaling pathway GO:0030177 45 0.020
endocardium development GO:0003157 10 0.020
non canonical wnt signaling pathway GO:0035567 33 0.019
regulation of myelination GO:0031641 20 0.019

Mks1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
joubert syndrome DOID:0050777 0 0.688
physical disorder DOID:0080015 0 0.077
nephronophthisis DOID:12712 0 0.063
disease of anatomical entity DOID:7 0 0.048
cardiovascular system disease DOID:1287 0 0.048
musculoskeletal system disease DOID:17 0 0.042
connective tissue disease DOID:65 0 0.042
sensory system disease DOID:0050155 0 0.023
nervous system disease DOID:863 0 0.023