|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
1.000
|
|
|
|
cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0002361 |
4 |
0.996
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.996
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.995
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.994
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.991
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.980
|
|
|
|
positive regulation of t cell mediated cytotoxicity
|
GO:0001916 |
15 |
0.980
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.979
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.969
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.958
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.956
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.954
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.951
|
|
|
|
regulation of tolerance induction dependent upon immune response
|
GO:0002652 |
1 |
0.951
|
|
|
|
positive regulation of type ii hypersensitivity
|
GO:0002894 |
4 |
0.947
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.934
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
14 |
0.930
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.926
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.925
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.921
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.909
|
|
|
|
negative regulation of toll like receptor 2 signaling pathway
|
GO:0034136 |
3 |
0.908
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.880
|
|
|
|
regulation of isotype switching to igg isotypes
|
GO:0048302 |
10 |
0.865
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.844
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.843
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.836
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.835
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.833
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.814
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.809
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.807
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.795
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.790
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.787
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.786
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.783
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.779
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.765
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.758
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.751
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.749
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.743
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.722
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.721
|
|
|
|
myeloid leukocyte cytokine production
|
GO:0061082 |
12 |
0.721
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.713
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.702
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.697
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.691
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.688
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.683
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.678
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.663
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.663
|
|
|
|
negative regulation of interleukin 2 biosynthetic process
|
GO:0045085 |
3 |
0.657
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.653
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.644
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.619
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.611
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.609
|
|
|
|
serotonin secretion involved in inflammatory response
|
GO:0002442 |
4 |
0.600
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.598
|
|
|
|
positive regulation of type iii hypersensitivity
|
GO:0001805 |
3 |
0.595
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.587
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.586
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.570
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.570
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.551
|
|
|
|
negative regulation of t cell mediated cytotoxicity
|
GO:0001915 |
3 |
0.551
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.548
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.543
|
|
|
|
learned vocalization behavior or vocal learning
|
GO:0098598 |
1 |
0.536
|
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.530
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.521
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.514
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.484
|
|
|
|
somatic diversification of t cell receptor genes
|
GO:0002568 |
5 |
0.484
|
|
|
|
antigen processing and presentation of exogenous antigen
|
GO:0019884 |
26 |
0.481
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.473
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.462
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.457
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.454
|
|
|
|
fc receptor mediated stimulatory signaling pathway
|
GO:0002431 |
4 |
0.453
|
|
|
|
negative regulation of chronic inflammatory response
|
GO:0002677 |
3 |
0.444
|
|
|
|
v d j recombination
|
GO:0033151 |
14 |
0.440
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.438
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.426
|
|
|
|
regulation of cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0032829 |
2 |
0.414
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.408
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.401
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.396
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.395
|
|
|
|
regulation of type iia hypersensitivity
|
GO:0001796 |
4 |
0.395
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.395
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.387
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.386
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.378
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.375
|
|
|
|
filtration diaphragm assembly
|
GO:0036058 |
1 |
0.375
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.373
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.371
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.366
|
|
|
|
serotonin production involved in inflammatory response
|
GO:0002351 |
4 |
0.357
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.356
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.355
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.350
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.349
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.344
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.344
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.343
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.343
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.342
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.341
|
|
|
|
positive regulation of translational initiation
|
GO:0045948 |
4 |
0.341
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.325
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.323
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.317
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.312
|
|
|
|
fc epsilon receptor signaling pathway
|
GO:0038095 |
3 |
0.311
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.310
|
|
|
|
positive regulation of lymphocyte anergy
|
GO:0002913 |
4 |
0.306
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.306
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.299
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
8 |
0.298
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.297
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.290
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
20 |
0.290
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.288
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.286
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.285
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.280
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.279
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.278
|
|
|
|
negative regulation of t cell mediated immunity
|
GO:0002710 |
9 |
0.277
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.272
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.255
|
|
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.253
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.252
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.251
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.250
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.248
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.246
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.245
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.244
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.244
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.242
|
|
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
7 |
0.237
|
|
|
|
regulation of chronic inflammatory response to antigenic stimulus
|
GO:0002874 |
3 |
0.236
|
|
|
|
interleukin 6 biosynthetic process
|
GO:0042226 |
12 |
0.236
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.232
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.232
|
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.232
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.232
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.231
|
|
|
|
antigen processing and presentation of exogenous peptide antigen
|
GO:0002478 |
21 |
0.229
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
2 |
0.228
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.226
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.224
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.221
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.221
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.219
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.217
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.217
|
|
|
|
antigen processing and presentation of peptide antigen
|
GO:0048002 |
29 |
0.212
|
|
|
|
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii
|
GO:0002504 |
17 |
0.212
|
|
|
|
positive regulation of antibacterial peptide production
|
GO:0002803 |
1 |
0.211
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.210
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.208
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.207
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.207
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.204
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.203
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.199
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.198
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.198
|
|
|
|
positive regulation of t cell mediated immunity
|
GO:0002711 |
24 |
0.195
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.194
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.194
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.193
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.192
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.192
|
|
|
|
imitative learning
|
GO:0098596 |
1 |
0.184
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.184
|
|
|
|
protection from non homologous end joining at telomere
|
GO:0031848 |
4 |
0.183
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.180
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.178
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.177
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.175
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.175
|
|
|
|
regulation of platelet activation
|
GO:0010543 |
17 |
0.174
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.168
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.168
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.167
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.166
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.164
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.163
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.163
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.162
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.160
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.159
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.159
|
|
|
|
chronic inflammatory response
|
GO:0002544 |
9 |
0.158
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.158
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.157
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.155
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:0097296 |
2 |
0.153
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.153
|
|
|
|
negative regulation of cell adhesion involved in substrate bound cell migration
|
GO:0006933 |
3 |
0.151
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.150
|
|
|
|
regulation of transforming growth factor beta1 production
|
GO:0032908 |
3 |
0.149
|
|
|
|
gamma delta t cell activation
|
GO:0046629 |
13 |
0.148
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.145
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
15 |
0.145
|
|
|
|
regulation of type iii hypersensitivity
|
GO:0001803 |
3 |
0.144
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.144
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.144
|
|
|
|
neutrophil activation involved in immune response
|
GO:0002283 |
8 |
0.144
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.143
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.142
|
|
|
|
positive regulation of t cell anergy
|
GO:0002669 |
4 |
0.142
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.141
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.141
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.139
|
|
|
|
positive regulation of cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0032831 |
2 |
0.139
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.139
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.138
|
|
|
|
telomere maintenance in response to dna damage
|
GO:0043247 |
4 |
0.138
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.138
|
|
|
|
transforming growth factor beta1 production
|
GO:0032905 |
3 |
0.137
|
|
|
|
positive regulation of dna recombination
|
GO:0045911 |
17 |
0.137
|
|
|
|
positive regulation of chronic inflammatory response
|
GO:0002678 |
4 |
0.136
|
|
|
|
t cell mediated cytotoxicity
|
GO:0001913 |
26 |
0.136
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.136
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.135
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.134
|
|
|
|
b cell lineage commitment
|
GO:0002326 |
4 |
0.133
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.133
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.133
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.132
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.129
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.126
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.125
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.125
|
|
|
|
lymphocyte anergy
|
GO:0002249 |
4 |
0.124
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.123
|
|
|
|
pre b cell differentiation
|
GO:0002329 |
7 |
0.123
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.123
|
|
|
|
neuroblast fate determination
|
GO:0007400 |
1 |
0.121
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.120
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.120
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.119
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.118
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.116
|
|
|
|
fc receptor signaling pathway
|
GO:0038093 |
6 |
0.115
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.114
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.113
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.113
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.112
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.112
|
|
|
|
t cell receptor v d j recombination
|
GO:0033153 |
5 |
0.110
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.110
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.109
|
|
|
|
regulation of lymphocyte anergy
|
GO:0002911 |
4 |
0.109
|
|
|
|
positive regulation of mast cell activation involved in immune response
|
GO:0033008 |
10 |
0.109
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.109
|
|
|
|
vocal learning
|
GO:0042297 |
1 |
0.109
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.107
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.107
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.106
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.106
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.105
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.104
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.102
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.101
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.100
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.100
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.099
|
|
|
|
antigen processing and presentation of exogenous peptide antigen via mhc class i
|
GO:0042590 |
6 |
0.099
|
|
|
|
regulation of t cell differentiation in thymus
|
GO:0033081 |
24 |
0.098
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.097
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
18 |
0.097
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.097
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.097
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.096
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.095
|
|
|
|
immunoglobulin v d j recombination
|
GO:0033152 |
5 |
0.094
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.094
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.093
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.093
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.093
|
|
|
|
observational learning
|
GO:0098597 |
1 |
0.092
|
|
|
|
immature b cell differentiation
|
GO:0002327 |
10 |
0.092
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.091
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.091
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.090
|
|
|
|
regulation of t cell mediated cytotoxicity
|
GO:0001914 |
18 |
0.089
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.089
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.086
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.086
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.086
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.085
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.085
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.085
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.084
|
|
|
|
neutrophil activation
|
GO:0042119 |
9 |
0.084
|
|
|
|
transmembrane receptor protein tyrosine phosphatase signaling pathway
|
GO:0007185 |
1 |
0.083
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.083
|
|
|
|
regulation of dendritic cell cytokine production
|
GO:0002730 |
2 |
0.083
|
|
|
|
negative regulation of lymphocyte mediated immunity
|
GO:0002707 |
21 |
0.082
|
|
|
|
negative regulation of interleukin 2 production
|
GO:0032703 |
8 |
0.081
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
46 |
0.081
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.080
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.080
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.079
|
|
|
|
telomere capping
|
GO:0016233 |
4 |
0.079
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.079
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.078
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.078
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.078
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.078
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.078
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.077
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.077
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
28 |
0.076
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.076
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.076
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.075
|
|
|
|
positive regulation of b cell differentiation
|
GO:0045579 |
13 |
0.075
|
|
|
|
positive regulation of transforming growth factor beta1 production
|
GO:0032914 |
2 |
0.075
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.073
|
|
|
|
negative regulation of histone deacetylation
|
GO:0031064 |
2 |
0.073
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.073
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.073
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.072
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.072
|
|
|
|
positive regulation of interleukin 10 production
|
GO:0032733 |
12 |
0.072
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.071
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.070
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.070
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.069
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.069
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.069
|
|
|
|
nk t cell differentiation
|
GO:0001865 |
8 |
0.069
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.068
|
|
|
|
negative regulation of myeloid dendritic cell activation
|
GO:0030886 |
3 |
0.068
|
|
|
|
telomere maintenance
|
GO:0000723 |
19 |
0.068
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.067
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.067
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.067
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.066
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.066
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.065
|
|
|
|
type ii hypersensitivity
|
GO:0002445 |
4 |
0.065
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.064
|
|
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
10 |
0.064
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.063
|
|
|
|
neutrophil differentiation
|
GO:0030223 |
3 |
0.062
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.062
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.062
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.062
|
|
|
|
negative regulation of mast cell activation
|
GO:0033004 |
6 |
0.062
|
|
|
|
negative regulation of toll like receptor 4 signaling pathway
|
GO:0034144 |
3 |
0.061
|
|
|
|
endoderm formation
|
GO:0001706 |
20 |
0.061
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.060
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.060
|
|
|
|
negative regulation of creb transcription factor activity
|
GO:0032792 |
2 |
0.060
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.060
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.059
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
10 |
0.059
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.059
|
|
|
|
regulation of type ii hypersensitivity
|
GO:0002892 |
4 |
0.059
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.058
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.058
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.058
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.057
|
|
|
|
spinal cord development
|
GO:0021510 |
81 |
0.055
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.055
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.055
|
|
|
|
positive regulation of interleukin 1 secretion
|
GO:0050716 |
14 |
0.054
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.054
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.054
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.053
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.053
|
|
|
|
cellular zinc ion homeostasis
|
GO:0006882 |
9 |
0.053
|
|
|
|
stem cell fate determination
|
GO:0048867 |
2 |
0.053
|
|
|
|
regulation of translational initiation
|
GO:0006446 |
15 |
0.053
|
|
|
|
t cell homeostatic proliferation
|
GO:0001777 |
4 |
0.053
|
|
|
|
positive regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002925 |
6 |
0.053
|
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
19 |
0.053
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.053
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
6 |
0.053
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.053
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.052
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.052
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.052
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.052
|
|
|
|
neutrophil apoptotic process
|
GO:0001781 |
3 |
0.051
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.051
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.051
|
|
|
|
regulation of hypersensitivity
|
GO:0002883 |
10 |
0.051
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.050
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.050
|
|
|
|
positive regulation of tolerance induction dependent upon immune response
|
GO:0002654 |
1 |
0.050
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.050
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.050
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.049
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.049
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.049
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.049
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.048
|
|
|
|
negative regulation of mast cell apoptotic process
|
GO:0033026 |
4 |
0.047
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.047
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.047
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.047
|
|
|
|
natural killer cell differentiation
|
GO:0001779 |
21 |
0.047
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.047
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.046
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.046
|
|
|
|
fibroblast migration
|
GO:0010761 |
21 |
0.046
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.046
|
|
|
|
t cell anergy
|
GO:0002870 |
4 |
0.046
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.046
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.046
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.046
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.045
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.045
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.045
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.045
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.045
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.045
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.044
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.044
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.044
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.044
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.043
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
15 |
0.043
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.042
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.042
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.042
|
|
|
|
neuroblast differentiation
|
GO:0014016 |
2 |
0.042
|
|
|
|
negative regulation of interferon gamma production
|
GO:0032689 |
18 |
0.041
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.041
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.041
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.041
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.041
|
|
|
|
ripoptosome assembly involved in necroptotic process
|
GO:1901026 |
6 |
0.041
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.041
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.041
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.040
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.040
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.040
|
|
|
|
regulation of podosome assembly
|
GO:0071801 |
3 |
0.040
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.040
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.039
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.039
|
|
|
|
regulation of peripheral t cell tolerance induction
|
GO:0002849 |
1 |
0.039
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.039
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.038
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.038
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.037
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.037
|
|
|
|
antigen processing and presentation of peptide antigen via mhc class ii
|
GO:0002495 |
17 |
0.037
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.037
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.037
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.036
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
2 |
0.036
|
|
|
|
transition metal ion homeostasis
|
GO:0055076 |
54 |
0.036
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.036
|
|
|
|
positive regulation of type i hypersensitivity
|
GO:0001812 |
3 |
0.035
|
|
|
|
regulation of gamma delta t cell activation
|
GO:0046643 |
9 |
0.035
|
|
|
|
positive regulation of myeloid leukocyte cytokine production involved in immune response
|
GO:0061081 |
9 |
0.035
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.035
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
3 |
0.035
|
|
|
|
non recombinational repair
|
GO:0000726 |
10 |
0.035
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.035
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
9 |
0.034
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
36 |
0.034
|
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.034
|
|
|
|
transformed cell apoptotic process
|
GO:0006927 |
3 |
0.033
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.033
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.032
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.032
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.032
|
|
