IMP
Process View
negative regulation of rig i signaling pathway
Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of rig i signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.149 | ||
| IFIH1 | interferon induced with helicase C domain 1 | 0.131 | Human | |
| SAMD9L | sterile alpha motif domain containing 9-like | 0.054 | ||
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 0.028 | ||
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.021 | ||
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.018 | ||
| IFI44 | interferon-induced protein 44 | 0.015 | ||
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.015 | ||
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.014 | ||
| CYLD | cylindromatosis (turban tumor syndrome) | 0.013 | ||
| EIF2C2 | eukaryotic translation initiation factor 2C, 2 | 0.012 | ||
| TARBP2 | TAR (HIV-1) RNA binding protein 2 | 0.012 | ||
| SAMD9 | sterile alpha motif domain containing 9 | 0.012 | ||
| HERC5 | hect domain and RLD 5 | 0.011 |