IMP

Process View

Homo sapiens

4 genes annotated in human

toxin metabolic process

The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "toxin metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "toxin metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.955	Fly
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.720	Fly
C12orf23	chromosome 12 open reading frame 23	0.464
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.409
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.355	Fly
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.354	Fly
TRAM1	translocation associated membrane protein 1	0.298
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.216
C6	complement component 6	0.196
SSR1	signal sequence receptor, alpha	0.181
FMO4	flavin containing monooxygenase 4	0.121	Human
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.076
ERLEC1	endoplasmic reticulum lectin 1	0.066
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.064
F9	coagulation factor IX	0.052
YIPF6	Yip1 domain family, member 6	0.051
SCOC	short coiled-coil protein	0.049
ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	0.046
AADAC	arylacetamide deacetylase (esterase)	0.042
NUCB2	nucleobindin 2	0.039
SLC33A1	solute carrier family 33 (acetyl-CoA transporter), member 1	0.038
CCL16	chemokine (C-C motif) ligand 16	0.037
GOLGA4	golgin A4	0.035
BET1	blocked early in transport 1 homolog (S. cerevisiae)	0.035
PON3	paraoxonase 3	0.034
HOXA1	homeobox A1	0.033
C8A	complement component 8, alpha polypeptide	0.032
OSTC	oligosaccharyltransferase complex subunit	0.030
GCC2	GRIP and coiled-coil domain containing 2	0.030
GOLGA5	golgin A5	0.030
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.028
ADH1A	alcohol dehydrogenase 1A (class I), alpha polypeptide	0.028
ACBD3	acyl-CoA binding domain containing 3	0.027
COG5	component of oligomeric golgi complex 5	0.026
FMO1	flavin containing monooxygenase 1	0.026
SPP2	secreted phosphoprotein 2, 24kDa	0.025
ATOH8	atonal homolog 8 (Drosophila)	0.025
ABCA6	ATP-binding cassette, sub-family A (ABC1), member 6	0.024
XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.024
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.024
GFPT1	glutamine--fructose-6-phosphate transaminase 1	0.024
GIGYF1	GRB10 interacting GYF protein 1	0.024
PON1	paraoxonase 1	0.024
TMEM50B	transmembrane protein 50B	0.024
COPB2	coatomer protein complex, subunit beta 2 (beta prime)	0.024
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.022
PGM3	phosphoglucomutase 3	0.022
PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide	0.022
AOX1	aldehyde oxidase 1	0.022
FMO5	flavin containing monooxygenase 5	0.021	Human
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.021
CRP	C-reactive protein, pentraxin-related	0.021
KNG1	kininogen 1	0.020
FHL5	four and a half LIM domains 5	0.020
USO1	USO1 vesicle docking protein homolog (yeast)	0.020
OMD	osteomodulin	0.019
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.019
TMPRSS2	transmembrane protease, serine 2	0.019
C20orf30	chromosome 20 open reading frame 30	0.019
DAO	D-amino-acid oxidase	0.018
PAH	phenylalanine hydroxylase	0.018
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.018
C4BPB	complement component 4 binding protein, beta	0.018
UGT2B15	UDP glucuronosyltransferase 2 family, polypeptide B15	0.018
F11	coagulation factor XI	0.018
MASP2	mannan-binding lectin serine peptidase 2	0.017
TLR5	toll-like receptor 5	0.017
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.017
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.017
ITIH2	inter-alpha (globulin) inhibitor H2	0.017
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.017
CFHR2	complement factor H-related 2	0.017
PRG4	proteoglycan 4	0.016
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.016
RDH13	retinol dehydrogenase 13 (all-trans/9-cis)	0.016
SLC6A13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	0.016
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.016
RASSF9	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9	0.016
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.016
GSTM5	glutathione S-transferase mu 5	0.016
ASPA	aspartoacylase	0.016
CNGA1	cyclic nucleotide gated channel alpha 1	0.016
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.015
SLC38A6	solute carrier family 38, member 6	0.015
VNN1	vanin 1	0.015
PRKG2	protein kinase, cGMP-dependent, type II	0.015
OTC	ornithine carbamoyltransferase	0.015
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.015
MAOA	monoamine oxidase A	0.015
TM4SF4	transmembrane 4 L six family member 4	0.015
SLC17A3	solute carrier family 17 (sodium phosphate), member 3	0.015
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.015
LMAN1	lectin, mannose-binding, 1	0.015
IER3IP1	immediate early response 3 interacting protein 1	0.015
CYP7B1	cytochrome P450, family 7, subfamily B, polypeptide 1	0.015
GSTA1	glutathione S-transferase alpha 1	0.014
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.014
GFI1B	growth factor independent 1B transcription repressor	0.014
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.014
GYS2	glycogen synthase 2 (liver)	0.014
ENPP3	ectonucleotide pyrophosphatase/phosphodiesterase 3	0.014
FMO3	flavin containing monooxygenase 3	0.014	Human
GK	glycerol kinase	0.014
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.014
VIL1	villin 1	0.014
MBL2	mannose-binding lectin (protein C) 2, soluble	0.014
APOB	apolipoprotein B (including Ag(x) antigen)	0.014
UGT2B28	UDP glucuronosyltransferase 2 family, polypeptide B28	0.014
C7	complement component 7	0.014
PRRC1	proline-rich coiled-coil 1	0.013
CLDN8	claudin 8	0.013
AFM	afamin	0.013
UGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17	0.013
TXNDC15	thioredoxin domain containing 15	0.013
CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1	0.013
C8B	complement component 8, beta polypeptide	0.013
ADH6	alcohol dehydrogenase 6 (class V)	0.013
RAD54L2	RAD54-like 2 (S. cerevisiae)	0.013
GSTA3	glutathione S-transferase alpha 3	0.013
ENPEP	glutamyl aminopeptidase (aminopeptidase A)	0.013
LGALS4	lectin, galactoside-binding, soluble, 4	0.013
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.013
SLC19A3	solute carrier family 19, member 3	0.012
CDO1	cysteine dioxygenase, type I	0.012
ERN1	endoplasmic reticulum to nucleus signaling 1	0.012
SLC7A9	solute carrier family 7 (cationic amino acid transporter, y+ system), member 9	0.012
HRG	histidine-rich glycoprotein	0.012
ADIPOQ	adiponectin, C1Q and collagen domain containing	0.012
PLIN1	perilipin 1	0.012
APCS	amyloid P component, serum	0.012
ASB4	ankyrin repeat and SOCS box containing 4	0.012
CLEC1A	C-type lectin domain family 1, member A	0.012
PDZK1	PDZ domain containing 1	0.012
CYP11A1	cytochrome P450, family 11, subfamily A, polypeptide 1	0.012
LECT2	leukocyte cell-derived chemotaxin 2	0.012
CPA3	carboxypeptidase A3 (mast cell)	0.012
IGFBP1	insulin-like growth factor binding protein 1	0.012
CMPK1	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	0.012
YIPF5	Yip1 domain family, member 5	0.012
SULT1E1	sulfotransferase family 1E, estrogen-preferring, member 1	0.011
ACSL5	acyl-CoA synthetase long-chain family member 5	0.011
CILP	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase	0.011
LRP2	low density lipoprotein receptor-related protein 2	0.011
ALDH1L1	aldehyde dehydrogenase 1 family, member L1	0.011
WDR5B	WD repeat domain 5B	0.011
HPGDS	hematopoietic prostaglandin D synthase	0.011
OLFML1	olfactomedin-like 1	0.011
GREM2	gremlin 2	0.011
PGRMC1	progesterone receptor membrane component 1	0.011
LYVE1	lymphatic vessel endothelial hyaluronan receptor 1	0.011
MTTP	microsomal triglyceride transfer protein	0.011
RPAIN	RPA interacting protein	0.011
GSTT1	glutathione S-transferase theta 1	0.011
GDPD4	glycerophosphodiester phosphodiesterase domain containing 4	0.011
AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)	0.011
FABP4	fatty acid binding protein 4, adipocyte	0.011
ITGA8	integrin, alpha 8	0.011
SEC22B	SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)	0.011
NTS	neurotensin	0.011
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.011
ANXA10	annexin A10	0.011
TMBIM4	transmembrane BAX inhibitor motif containing 4	0.011
DNASE1L3	deoxyribonuclease I-like 3	0.011
GLYAT	glycine-N-acyltransferase	0.011
WASF2	WAS protein family, member 2	0.011
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.011
DPYS	dihydropyrimidinase	0.011
GPX2	glutathione peroxidase 2 (gastrointestinal)	0.011
ZNF132	zinc finger protein 132	0.011
NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.011
C4BPA	complement component 4 binding protein, alpha	0.011
GC	group-specific component (vitamin D binding protein)	0.011
CFI	complement factor I	0.011
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.011
RNF170	ring finger protein 170	0.011
DEFB1	defensin, beta 1	0.011
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.010
CLCA4	chloride channel accessory 4	0.010
C5orf4	chromosome 5 open reading frame 4	0.010
LRRC31	leucine rich repeat containing 31	0.010
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.010
PGRMC2	progesterone receptor membrane component 2	0.010
CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2	0.010
TSPAN8	tetraspanin 8	0.010
TMEM30A	transmembrane protein 30A	0.010
SPINK1	serine peptidase inhibitor, Kazal type 1	0.010
RGL1	ral guanine nucleotide dissociation stimulator-like 1	0.010
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.010
SCN7A	sodium channel, voltage-gated, type VII, alpha	0.010