IMP
Process View
proximal tubule development
The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "proximal tubule development"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| JAG1 | jagged 1 | 0.925 | ||
| NOTCH1 | notch 1 | 0.836 | ||
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.676 | ||
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.376 | ||
| NOTCH3 | notch 3 | 0.301 | ||
| NOTCH2NL | notch 2 N-terminal like | 0.241 | ||
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.197 | ||
| RBPMS | RNA binding protein with multiple splicing | 0.147 | ||
| NPHP1 | nephronophthisis 1 (juvenile) | 0.121 | ||
| PAM | peptidylglycine alpha-amidating monooxygenase | 0.098 | ||
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.055 | ||
| HEY1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.053 | ||
| ZNF512B | zinc finger protein 512B | 0.052 | ||
| SKIL | SKI-like oncogene | 0.047 | ||
| C3orf64 | chromosome 3 open reading frame 64 | 0.046 | ||
| DIAPH1 | diaphanous homolog 1 (Drosophila) | 0.043 | ||
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.037 | ||
| NOTCH2 | notch 2 | 0.036 | Mouse | |
| DLL1 | delta-like 1 (Drosophila) | 0.036 | Mouse | |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 0.034 | ||
| SMAD9 | SMAD family member 9 | 0.030 | ||
| JAG2 | jagged 2 | 0.027 | ||
| CXXC5 | CXXC finger protein 5 | 0.026 | ||
| DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial | 0.026 | ||
| SMAD1 | SMAD family member 1 | 0.025 | ||
| ATP10D | ATPase, class V, type 10D | 0.021 | ||
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.019 | ||
| PDGFC | platelet derived growth factor C | 0.017 | ||
| ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.016 | ||
| ACVR1 | activin A receptor, type I | 0.014 | ||
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.014 | ||
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.013 | ||
| NCOR2 | nuclear receptor corepressor 2 | 0.012 | ||
| CHPF | chondroitin polymerizing factor | 0.011 | ||
| HEG1 | HEG homolog 1 (zebrafish) | 0.011 | ||
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.011 | ||
| PLSCR4 | phospholipid scramblase 4 | 0.010 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.010 |