IMP
Process View
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves.
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Click on a gene's description to view its network relationships with genes known to be involved in "nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| SMAD3 | SMAD family member 3 | 1.000 | Human | |
| SMAD1 | SMAD family member 1 | 1.000 | Human | |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.966 | ||
| SMAD4 | SMAD family member 4 | 0.902 | Human | |
| SMAD2 | SMAD family member 2 | 0.858 | ||
| SMAD7 | SMAD family member 7 | 0.613 | Human | |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.452 | ||
| SMAD5 | SMAD family member 5 | 0.307 | Human | |
| SKIL | SKI-like oncogene | 0.307 | ||
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.217 | ||
| CXXC5 | CXXC finger protein 5 | 0.118 | ||
| DCP1A | DCP1 decapping enzyme homolog A (S. cerevisiae) | 0.089 | ||
| SP1 | Sp1 transcription factor | 0.046 | ||
| RNF11 | ring finger protein 11 | 0.029 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.024 | ||
| ZMYM2 | zinc finger, MYM-type 2 | 0.022 | ||
| ATF7IP | activating transcription factor 7 interacting protein | 0.022 | ||
| TRAF4 | TNF receptor-associated factor 4 | 0.022 | ||
| SMAD6 | SMAD family member 6 | 0.019 | Human | |
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.018 | ||
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.014 | ||
| EP300 | E1A binding protein p300 | 0.013 | ||
| SOX7 | SRY (sex determining region Y)-box 7 | 0.011 | ||
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.010 |