IMP

Process View

Homo sapiens

2 genes annotated in human

leukotriene b4 catabolic process

The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "leukotriene b4 catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "leukotriene b4 catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.951
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.870
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.538	Human
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.517	Human
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.423
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.243
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.192
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.161	Human
FABP1	fatty acid binding protein 1, liver	0.128
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.090
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.081
KNG1	kininogen 1	0.077
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.058
C4BPA	complement component 4 binding protein, alpha	0.057
HAL	histidine ammonia-lyase	0.055
ADH6	alcohol dehydrogenase 6 (class V)	0.053
G6PC	glucose-6-phosphatase, catalytic subunit	0.051
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.050
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.047
ARG1	arginase, liver	0.046
C8A	complement component 8, alpha polypeptide	0.045
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.036
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.035
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.035
F9	coagulation factor IX	0.031
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.031
DAO	D-amino-acid oxidase	0.031
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.029
MAT1A	methionine adenosyltransferase I, alpha	0.029
AADAC	arylacetamide deacetylase (esterase)	0.029
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.028
PLG	plasminogen	0.028
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.028
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.024
RDH16	retinol dehydrogenase 16 (all-trans)	0.023
OTC	ornithine carbamoyltransferase	0.022
HRG	histidine-rich glycoprotein	0.022
BHMT	betaine--homocysteine S-methyltransferase	0.021
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.020
SLC22A7	solute carrier family 22 (organic anion transporter), member 7	0.020
FETUB	fetuin B	0.019
PAH	phenylalanine hydroxylase	0.019
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.018
EPHX2	epoxide hydrolase 2, cytoplasmic	0.018
CDHR5	cadherin-related family member 5	0.018
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.017
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.017
HGD	homogentisate 1,2-dioxygenase	0.017
GSTA3	glutathione S-transferase alpha 3	0.017
APOC3	apolipoprotein C-III	0.017
GLYAT	glycine-N-acyltransferase	0.017
APOF	apolipoprotein F	0.017
CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	0.016
TMPRSS4	transmembrane protease, serine 4	0.016
MASP2	mannan-binding lectin serine peptidase 2	0.016
C8G	complement component 8, gamma polypeptide	0.016
F13B	coagulation factor XIII, B polypeptide	0.016
DEFB1	defensin, beta 1	0.016
IL22RA1	interleukin 22 receptor, alpha 1	0.016
SULT1E1	sulfotransferase family 1E, estrogen-preferring, member 1	0.015
CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	0.015	Human
PIP	prolactin-induced protein	0.015
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.015
CPB2	carboxypeptidase B2 (plasma)	0.015
SEC14L2	SEC14-like 2 (S. cerevisiae)	0.015
HPD	4-hydroxyphenylpyruvate dioxygenase	0.015
CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2	0.015
C8B	complement component 8, beta polypeptide	0.015
HAO1	hydroxyacid oxidase (glycolate oxidase) 1	0.015
NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.014
ORM1	orosomucoid 1	0.014
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.014
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.014
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.014
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.014
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.014
PIPOX	pipecolic acid oxidase	0.014
C9	complement component 9	0.013
APOC4	apolipoprotein C-IV	0.013
KRT13	keratin 13	0.013
FMO4	flavin containing monooxygenase 4	0.013
PRLR	prolactin receptor	0.013
DIO1	deiodinase, iodothyronine, type I	0.012
LIPC	lipase, hepatic	0.012
CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1	0.012
LPA	lipoprotein, Lp(a)	0.012
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.012
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.012
CFHR4	complement factor H-related 4	0.011
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.011
FABP2	fatty acid binding protein 2, intestinal	0.011
SLC25A47	solute carrier family 25, member 47	0.011
F5	coagulation factor V (proaccelerin, labile factor)	0.011
AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)	0.011
LECT2	leukocyte cell-derived chemotaxin 2	0.011
GSTT1	glutathione S-transferase theta 1	0.011
CRISP3	cysteine-rich secretory protein 3	0.011
NAT8	N-acetyltransferase 8 (GCN5-related, putative)	0.010
HPX	hemopexin	0.010
PLEKHG6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	0.010
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.010
CRP	C-reactive protein, pentraxin-related	0.010
GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	0.010
DPYS	dihydropyrimidinase	0.010
HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2	0.010
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.010