IMP

Process View

Homo sapiens

10 genes annotated in human

drug catabolic process

The chemical reactions and pathways resulting in the breakdown of a drug, a substance used in the diagnosis, treatment or prevention of a disease.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "drug catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "drug catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	1.000
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	1.000
NCOR2	nuclear receptor corepressor 2	1.000
CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6	1.000
HNF4A	hepatocyte nuclear factor 4, alpha	1.000
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.980	Human
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.966	Human
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.964
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.956
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.926
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.882
VAC14	Vac14 homolog (S. cerevisiae)	0.865
HR	hairless homolog (mouse)	0.756
NCOR1	nuclear receptor corepressor 1	0.738
C6	complement component 6	0.689
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.670
CYP2A7	cytochrome P450, family 2, subfamily A, polypeptide 7	0.635	Human
HRG	histidine-rich glycoprotein	0.589
C8B	complement component 8, beta polypeptide	0.564
GLYAT	glycine-N-acyltransferase	0.518
ACRV1	acrosomal vesicle protein 1	0.510
RXRA	retinoid X receptor, alpha	0.486
DAO	D-amino-acid oxidase	0.453
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.446
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.406
ADH6	alcohol dehydrogenase 6 (class V)	0.390
C8A	complement component 8, alpha polypeptide	0.371
MASP2	mannan-binding lectin serine peptidase 2	0.356
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.317
CHD9	chromodomain helicase DNA binding protein 9	0.278
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.272
KNG1	kininogen 1	0.258
HDAC3	histone deacetylase 3	0.243
MAT1A	methionine adenosyltransferase I, alpha	0.233
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.211	Human
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.170
NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.161
F9	coagulation factor IX	0.160
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.159
OTC	ornithine carbamoyltransferase	0.138
CFHR4	complement factor H-related 4	0.123
PGR	progesterone receptor	0.114
NR1I3	nuclear receptor subfamily 1, group I, member 3	0.097	Human
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.090
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.089
AGXT2	alanine--glyoxylate aminotransferase 2	0.081
A1CF	APOBEC1 complementation factor	0.078
FMO4	flavin containing monooxygenase 4	0.075	Mouse
F11	coagulation factor XI	0.072
AADAC	arylacetamide deacetylase (esterase)	0.068
ALDOB	aldolase B, fructose-bisphosphate	0.064
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.061
HABP2	hyaluronan binding protein 2	0.059
APCS	amyloid P component, serum	0.056
RARA	retinoic acid receptor, alpha	0.051
UGT2B15	UDP glucuronosyltransferase 2 family, polypeptide B15	0.047
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.047
PPARA	peroxisome proliferator-activated receptor alpha	0.043	Human
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.041
C4BPA	complement component 4 binding protein, alpha	0.036
HAO1	hydroxyacid oxidase (glycolate oxidase) 1	0.036
PON1	paraoxonase 1	0.035
MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	0.034
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6	0.033
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.033
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.032
XDH	xanthine dehydrogenase	0.032
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.032
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.031
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.030	Human
CCL16	chemokine (C-C motif) ligand 16	0.029
BHMT	betaine--homocysteine S-methyltransferase	0.028
TAT	tyrosine aminotransferase	0.027
BCL6	B-cell CLL/lymphoma 6	0.027
ITIH4	inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)	0.027
MTTP	microsomal triglyceride transfer protein	0.026
PZP	pregnancy-zone protein	0.026
PPARG	peroxisome proliferator-activated receptor gamma	0.026	Human
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.025
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.021
APOC4	apolipoprotein C-IV	0.021
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.021
GPLD1	glycosylphosphatidylinositol specific phospholipase D1	0.020
F13B	coagulation factor XIII, B polypeptide	0.020
AFM	afamin	0.019
TM4SF4	transmembrane 4 L six family member 4	0.018
FETUB	fetuin B	0.017
GYS2	glycogen synthase 2 (liver)	0.017
TTPA	tocopherol (alpha) transfer protein	0.016
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.016	Human
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.015
MEP1B	meprin A, beta	0.015
ITIH2	inter-alpha (globulin) inhibitor H2	0.014
CNGA1	cyclic nucleotide gated channel alpha 1	0.014
G6PC	glucose-6-phosphatase, catalytic subunit	0.014
HIPK2	homeodomain interacting protein kinase 2	0.014
GCKR	glucokinase (hexokinase 4) regulator	0.014
HPD	4-hydroxyphenylpyruvate dioxygenase	0.014
PLG	plasminogen	0.013
LECT2	leukocyte cell-derived chemotaxin 2	0.013
PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide	0.013
HNF1B	HNF1 homeobox B	0.013
RUNX1	runt-related transcription factor 1	0.013
CRP	C-reactive protein, pentraxin-related	0.012
ANXA10	annexin A10	0.012
TMPRSS6	transmembrane protease, serine 6	0.012
UGT1A1	UDP glucuronosyltransferase 1 family, polypeptide A1	0.012
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.011
TM4SF5	transmembrane 4 L six family member 5	0.011
DNASE1L3	deoxyribonuclease I-like 3	0.011
RORC	RAR-related orphan receptor C	0.011
SGK2	serum/glucocorticoid regulated kinase 2	0.010
ADH1A	alcohol dehydrogenase 1A (class I), alpha polypeptide	0.010
APOB	apolipoprotein B (including Ag(x) antigen)	0.010
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.010
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.010
C4BPB	complement component 4 binding protein, beta	0.010