IMP
Process View
amyloid precursor protein catabolic process
The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of beta-amyloid, a glycoprotein associated with Alzheimer's disease.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "amyloid precursor protein catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| NCSTN | nicastrin | 0.968 | ||
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.905 | ||
| PKP4 | plakophilin 4 | 0.609 | ||
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 | 0.403 | ||
| ACVR1B | activin A receptor, type IB | 0.310 | ||
| APH1A | anterior pharynx defective 1 homolog A (C. elegans) | 0.292 | ||
| PSEN1 | presenilin 1 | 0.236 | Zebrafish Mouse | |
| HP | haptoglobin | 0.230 | ||
| BCL2L1 | BCL2-like 1 | 0.155 | ||
| SYNRG | synergin, gamma | 0.150 | ||
| FLNB | filamin B, beta | 0.115 | ||
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.112 | ||
| PSENEN | presenilin enhancer 2 homolog (C. elegans) | 0.093 | ||
| APOC1 | apolipoprotein C-I | 0.090 | ||
| IGF2R | insulin-like growth factor 2 receptor | 0.088 | ||
| SORT1 | sortilin 1 | 0.059 | Human | |
| LCAT | lecithin-cholesterol acyltransferase | 0.057 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.052 | ||
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.049 | ||
| ALB | albumin | 0.043 | ||
| VAMP3 | vesicle-associated membrane protein 3 (cellubrevin) | 0.042 | ||
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.039 | ||
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.035 | ||
| APP | amyloid beta (A4) precursor protein | 0.030 | ||
| DHCR7 | 7-dehydrocholesterol reductase | 0.029 | ||
| CFL1 | cofilin 1 (non-muscle) | 0.029 | ||
| ARF3 | ADP-ribosylation factor 3 | 0.024 | ||
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.024 | ||
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) | 0.021 | ||
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.019 | ||
| COPA | coatomer protein complex, subunit alpha | 0.017 | ||
| APOC3 | apolipoprotein C-III | 0.015 | ||
| APOA2 | apolipoprotein A-II | 0.015 | ||
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.015 | ||
| ZFYVE1 | zinc finger, FYVE domain containing 1 | 0.014 | ||
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 0.014 | ||
| A2M | alpha-2-macroglobulin | 0.013 | ||
| BAD | BCL2-associated agonist of cell death | 0.013 | ||
| TAGLN2 | transgelin 2 | 0.012 | ||
| CLTC | clathrin, heavy chain (Hc) | 0.012 | ||
| RAB5A | RAB5A, member RAS oncogene family | 0.012 | ||
| RAB5C | RAB5C, member RAS oncogene family | 0.011 | ||
| RHOA | ras homolog gene family, member A | 0.011 | ||
| TTR | transthyretin | 0.011 | ||
| ECSIT | ECSIT homolog (Drosophila) | 0.011 |