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Process View

Homo sapiens

1 genes annotated in human

melanin biosynthetic process

The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.

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In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "melanin biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "melanin biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.927
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.578
DSG2	desmoglein 2	0.576
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.484
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.431
CTNND1	catenin (cadherin-associated protein), delta 1	0.354
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.270
JUP	junction plakoglobin	0.261
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.156	Human
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.120
PSEN1	presenilin 1	0.110
RAP1A	RAP1A, member of RAS oncogene family	0.086
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.069
DSP	desmoplakin	0.034
RAB27A	RAB27A, member RAS oncogene family	0.029
FGFR1	fibroblast growth factor receptor 1	0.026
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.022
GLIS2	GLIS family zinc finger 2	0.022
APC	adenomatous polyposis coli	0.020
TCF4	transcription factor 4	0.018
ATP8	ATP synthase F0 subunit 8	0.018
EGFR	epidermal growth factor receptor	0.017
CTNNBIP1	catenin, beta interacting protein 1	0.015
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.011
ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome	0.011
EMD	emerin	0.011
PKP3	plakophilin 3	0.011
PVR	poliovirus receptor	0.011
G6PC	glucose-6-phosphatase, catalytic subunit	0.011
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.010