IMP
Process View
adenylate cyclase inhibiting serotonin receptor signaling pathway
The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).
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Click on a gene's description to view its network relationships with genes known to be involved in "adenylate cyclase inhibiting serotonin receptor signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Olfr70 | olfactory receptor 70 | 0.145 | ||
| Kcnj6 | potassium inwardly-rectifying channel, subfamily J, member 6 | 0.112 | ||
| Sspo | SCO-spondin | 0.100 | ||
| Pou2f3 | POU domain, class 2, transcription factor 3 | 0.097 | ||
| Kcnq2 | potassium voltage-gated channel, subfamily Q, member 2 | 0.094 | ||
| Pax1 | paired box gene 1 | 0.090 | ||
| Ghrhr | growth hormone releasing hormone receptor | 0.084 | ||
| Tacr1 | tachykinin receptor 1 | 0.074 | ||
| Hoxb1 | homeobox B1 | 0.064 | ||
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.062 | ||
| Wnt1 | wingless-related MMTV integration site 1 | 0.058 | ||
| Pitx3 | paired-like homeodomain transcription factor 3 | 0.055 | ||
| Foxl1 | forkhead box L1 | 0.050 | ||
| Lhb | luteinizing hormone beta | 0.048 | ||
| Fshr | follicle stimulating hormone receptor | 0.048 | ||
| Chrm1 | cholinergic receptor, muscarinic 1, CNS | 0.047 | ||
| Foxn1 | forkhead box N1 | 0.046 | ||
| Tacr2 | tachykinin receptor 2 | 0.046 | ||
| Shbg | sex hormone binding globulin | 0.045 | ||
| Foxh1 | forkhead box H1 | 0.045 | ||
| Nkx1-2 | NK1 transcription factor related, locus 2 (Drosophila) | 0.042 | ||
| Drd2 | dopamine receptor D2 | 0.042 | ||
| Klf17 | Kruppel-like factor 17 | 0.040 | ||
| Htr1b | 5-hydroxytryptamine (serotonin) receptor 1B | 0.038 | Human | |
| C78513 | EST C78513 | 0.038 | ||
| Lalba | lactalbumin, alpha | 0.036 | ||
| Klk4 | kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) | 0.036 | ||
| Dnajb8 | DnaJ (Hsp40) homolog, subfamily B, member 8 | 0.035 | ||
| Tlx2 | T-cell leukemia, homeobox 2 | 0.031 | ||
| Cox8c | cytochrome c oxidase, subunit VIIIc | 0.030 | ||
| Odf1 | outer dense fiber of sperm tails 1 | 0.030 | ||
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.030 | ||
| Olfr71 | olfactory receptor 71 | 0.030 | ||
| A930012N16Rik | RIKEN cDNA A930012N16 gene | 0.028 | ||
| Vax1 | ventral anterior homeobox containing gene 1 | 0.027 | ||
| Prop1 | paired like homeodomain factor 1 | 0.027 | ||
| Neurod2 | neurogenic differentiation 2 | 0.026 | ||
| Krtap14 | keratin associated protein 14 | 0.026 | ||
| Prss29 | protease, serine, 29 | 0.026 | ||
| Oprm1 | opioid receptor, mu 1 | 0.026 | ||
| Hils1 | histone H1-like protein in spermatids 1 | 0.026 | ||
| Tcl1b1 | T-cell leukemia/lymphoma 1B, 1 | 0.025 | ||
| Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.024 | ||
| Itgb2l | integrin beta 2-like | 0.024 | ||
| Pspn | persephin | 0.024 | ||
| Evx2 | even skipped homeotic gene 2 homolog | 0.024 | ||
| Chrnb2 | cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) | 0.024 | ||
| Adra2c | adrenergic receptor, alpha 2c | 0.023 | ||
| Sox14 | SRY-box containing gene 14 | 0.023 | ||
| Gsx1 | GS homeobox 1 | 0.023 | ||
| AA511254 | expressed sequence AA511254 | 0.023 | ||
| Foxb1 | forkhead box B1 | 0.023 | ||
| Gpr44 | G protein-coupled receptor 44 | 0.022 | ||
| Hist1h1t | histone cluster 1, H1t | 0.022 | ||
| Olfr1264 | olfactory receptor 1264 | 0.021 | ||
| Eda | ectodysplasin-A | 0.021 | ||
| Gpr27 | G protein-coupled receptor 27 | 0.021 | ||
| Ppyr1 | pancreatic polypeptide receptor 1 | 0.019 | ||
| Epha8 | Eph receptor A8 | 0.019 | ||
| Ifna9 | interferon alpha 9 | 0.019 | ||
| Hmx1 | H6 homeobox 1 | 0.018 | ||
| Znrf4 | zinc and ring finger 4 | 0.018 | ||
| Brs3 | bombesin-like receptor 3 | 0.017 | ||
| Pmfbp1 | polyamine modulated factor 1 binding protein 1 | 0.017 | ||
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.017 | ||
| Lcn3 | lipocalin 3 | 0.017 | ||
| Htr1d | 5-hydroxytryptamine (serotonin) receptor 1D | 0.017 | ||
| Ifnab | interferon alpha B | 0.017 | ||
| Kcnh3 | potassium voltage-gated channel, subfamily H (eag-related), member 3 | 0.017 | ||
| Sebox | SEBOX homeobox | 0.016 | ||
| Cckbr | cholecystokinin B receptor | 0.016 | ||
| AF067063 | cDNA sequence AF067063 | 0.016 | ||
| Six3 | sine oculis-related homeobox 3 homolog (Drosophila) | 0.016 | ||
| Lhx3 | LIM homeobox protein 3 | 0.015 | ||
| Rbpjl | recombination signal binding protein for immunoglobulin kappa J region-like | 0.015 | ||
| Syt2 | synaptotagmin II | 0.015 | ||
| Foxd2 | forkhead box D2 | 0.015 | ||
| Syngr4 | synaptogyrin 4 | 0.015 | ||
| Srcin1 | SRC kinase signaling inhibitor 1 | 0.015 | ||
| Figla | folliculogenesis specific basic helix-loop-helix | 0.014 | ||
| Btn1a1 | butyrophilin, subfamily 1, member A1 | 0.014 | ||
| Hoxd13 | homeobox D13 | 0.014 | ||
| Galr3 | galanin receptor 3 | 0.013 | ||
| Prss40 | protease, serine, 40 | 0.013 | ||
| Sstr5 | somatostatin receptor 5 | 0.013 | ||
| Mmp24 | matrix metallopeptidase 24 | 0.013 | ||
| Gm2717 | predicted gene 2717 | 0.013 | ||
| Dlx4 | distal-less homeobox 4 | 0.013 | ||
| Amh | anti-Mullerian hormone | 0.012 | ||
| BC089491 | cDNA sequence BC089491 | 0.012 | ||
| Cfc1 | cripto, FRL-1, cryptic family 1 | 0.012 | ||
| Wnt7a | wingless-related MMTV integration site 7A | 0.012 | ||
| Rho | rhodopsin | 0.012 | ||
| Sstr3 | somatostatin receptor 3 | 0.012 | ||
| Slc18a3 | solute carrier family 18 (vesicular monoamine), member 3 | 0.012 | ||
| Nhlh1 | nescient helix loop helix 1 | 0.012 | ||
| Slc22a12 | solute carrier family 22 (organic anion/cation transporter), member 12 | 0.012 | ||
| Sncb | synuclein, beta | 0.011 | ||
| Ear4 | eosinophil-associated, ribonuclease A family, member 4 | 0.011 | ||
| Hoxb7 | homeobox B7 | 0.011 | ||
| Galr1 | galanin receptor 1 | 0.011 | ||
| Tyr | tyrosinase | 0.011 | ||
| Spi15 | serine protease inhibitor 15 | 0.011 | ||
| C79741 | expressed sequence C79741 | 0.011 | ||
| Cacng2 | calcium channel, voltage-dependent, gamma subunit 2 | 0.011 | ||
| Sox10 | SRY-box containing gene 10 | 0.011 | ||
| Zfp92 | zinc finger protein 92 | 0.011 | ||
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.011 | ||
| Wnt3a | wingless-related MMTV integration site 3A | 0.011 | ||
| Wap | whey acidic protein | 0.011 | ||
| Oxt | oxytocin | 0.010 | ||
| Hrk | harakiri, BCL2 interacting protein (contains only BH3 domain) | 0.010 | ||
| C77874 | expressed sequence C77874 | 0.010 | ||
| LOC100502924 | hypothetical protein LOC100502924 | 0.010 |