IMP

Process View

Rattus norvegicus

3 genes annotated in rat

serotonin metabolic process

The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "serotonin metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "serotonin metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Magi2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.102
Dlg4	discs, large homolog 4 (Drosophila)	0.098
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.082
Grin1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.079
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.073
Syt7	synaptotagmin VII	0.071
Abcc2	ATP-binding cassette, subfamily C (CFTR/MRP), member 2	0.069
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.043
Dlgap3	discs, large (Drosophila) homolog-associated protein 3	0.041
Cplx2	complexin 2	0.039
Cyp4f1	cytochrome P450, family 4, subfamily f, polypeptide 1	0.038
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.032
Nlgn3	neuroligin 3	0.031
Ppp1r9a	protein phosphatase 1, regulatory (inhibitor) subunit 9A	0.030
Lin7b	lin-7 homolog b (C. elegans)	0.030
Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	0.027
Ugt2b36	UDP glucuronosyltransferase 2 family, polypeptide B36	0.027
Cpn1	carboxypeptidase N, polypeptide 1	0.026
Grm3	glutamate receptor, metabotropic 3	0.025
Pgcp	plasma glutamate carboxypeptidase	0.025
Slc12a5	solute carrier family 12 (potassium-chloride transporter), member 5	0.025
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.024
Scp2	sterol carrier protein 2	0.023
Chrnb2	cholinergic receptor, nicotinic, beta 2 (neuronal)	0.022
Sult1b1	sulfotransferase family, cytosolic, 1B, member 1	0.022
Haao	3-hydroxyanthranilate 3,4-dioxygenase	0.021
Syt3	synaptotagmin III	0.020
Hpcal4	hippocalcin-like 4	0.019
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.019
Pzp	pregnancy-zone protein	0.018
Camk4	calcium/calmodulin-dependent protein kinase IV	0.017
Prkaa2	protein kinase, AMP-activated, alpha 2 catalytic subunit	0.017
Cpd	carboxypeptidase D	0.017
Bsn	bassoon	0.017
Mgat3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase	0.016
RGD1306474	similar to RIKEN cDNA 9530003J23	0.016
Gfra2	GDNF family receptor alpha 2	0.016
Sbp	spermine binding protein	0.016
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.016
Msmb	microseminoprotein, beta	0.015
Clec4f	C-type lectin domain family 4, member f	0.015
Abp10	annexin V-binding protein ABP-10	0.015
Prlr	prolactin receptor	0.015
Fn3k	fructosamine 3 kinase	0.014
Mpp3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	0.014
Slc9a1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.014
Gstm7	glutathione S-transferase, mu 7	0.014
Slc4a4	solute carrier family 4, sodium bicarbonate cotransporter, member 4	0.014
Wipf3	WAS/WASL interacting protein family, member 3	0.014
Tnni3	troponin I type 3 (cardiac)	0.014
Atp2c1	ATPase, Ca++ transporting, type 2C, member 1	0.014
Chrm3	cholinergic receptor, muscarinic 3	0.014
Slc40a1	solute carrier family 39 (iron-regulated transporter), member 1	0.013
A1bg	alpha-1-B glycoprotein	0.013
Ppp2r2c	protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform	0.013
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.013
Hoxb3	homeo box B3	0.013
Esr1	estrogen receptor 1	0.013
Aldh6a1	aldehyde dehydrogenase 6 family, member A1	0.013
Unc13a	unc-13 homolog A (C. elegans)	0.013
Rxrg	retinoid X receptor gamma	0.013
Cd59	CD59 molecule, complement regulatory protein	0.013
Gria1	glutamate receptor, ionotropic, AMPA 1	0.012
Hcrtr2	hypocretin (orexin) receptor 2	0.012
Nlrp6	NLR family, pyrin domain containing 6	0.012
Klk1c10	T-kininogenase	0.011
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.011
Dhcr7	7-dehydrocholesterol reductase	0.011
Vom2r18	vomeronasal 2 receptor, 18	0.011
Defb24	defensin beta 24	0.011
Lin7a	lin-7 homolog a (C. elegans)	0.011
Spp2	secreted phosphoprotein 2	0.011
Srd5a1	steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)	0.011
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.011
Hrsp12	heat-responsive protein 12	0.011
Matk	megakaryocyte-associated tyrosine kinase	0.011
Gabra1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.011
Syt17	synaptotagmin XVII	0.011
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.010	Mouse
Prl3b1	Prolactin family 3, subfamily b, member 1	0.010
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.010
Ugt2b	UDP glycosyltransferase 2 family, polypeptide B	0.010
Tyr	tyrosinase	0.010
Kcnk10	potassium channel, subfamily K, member 10	0.010
Npy5r	neuropeptide Y receptor Y5	0.010
Dpys	dihydropyrimidinase	0.010
Gjb1	gap junction protein, beta 1	0.010
Cpa4	carboxypeptidase A4	0.010
Sult2al1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1	0.010