IMP

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of tumor necrosis factor production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of tumor necrosis factor production" (in gray)

Name	Description	Probability	Func Analog Organism
Ccl7	chemokine (C-C motif) ligand 7	0.848	Rat
Ccl2	chemokine (C-C motif) ligand 2	0.436
Il1b	interleukin 1 beta	0.323
Cd14	CD14 molecule	0.304	Human
Igsf6	immunoglobulin superfamily, member 6	0.278
Timp1	TIMP metallopeptidase inhibitor 1	0.164
Cxcl10	chemokine (C-X-C motif) ligand 10	0.149
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.140
Ltbr	lymphotoxin beta receptor (TNFR superfamily, member 3)	0.140
Icam1	intercellular adhesion molecule 1	0.137
Plscr1	phospholipid scramblase 1	0.128
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.114
Ccl3	chemokine (C-C motif) ligand 3	0.098	Rat
C5ar1	complement component 5a receptor 1	0.092
Stat3	signal transducer and activator of transcription 3	0.092
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.088
Mmp12	matrix metallopeptidase 12	0.081
Ccr2	chemokine (C-C motif) receptor 2	0.077
Cd8a	CD8a molecule	0.071
Ccr5	chemokine (C-C motif) receptor 5	0.061
Ier3	immediate early response 3	0.055
Rgs1	regulator of G-protein signaling 1	0.054
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.054
Plau	plasminogen activator, urokinase	0.053
Il1r2	interleukin 1 receptor, type II	0.043
Nkg7	natural killer cell group 7 sequence	0.042
Ccl4	chemokine (C-C motif) ligand 4	0.042
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.041
Xcl1	chemokine (C motif) ligand 1	0.039	Rat
Tlr2	toll-like receptor 2	0.037
Smad1	SMAD family member 1	0.037
Litaf	lipopolysaccharide-induced TNF factor	0.037
Hmox1	heme oxygenase (decycling) 1	0.036
Acsl1	acyl-CoA synthetase long-chain family member 1	0.035
Ccl20	chemokine (C-C motif) ligand 20	0.035	Rat
Cxcl2	chemokine (C-X-C motif) ligand 2	0.031
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.031
Sell	selectin L	0.029
Cfd	complement factor D (adipsin)	0.029
Itgam	integrin, alpha M	0.029
Hpgds	hematopoietic prostaglandin D synthase	0.029
Reg3b	regenerating islet-derived 3 beta	0.027
Adrb2	adrenergic, beta-2-, receptor, surface	0.027
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.027
Slpi	secretory leukocyte peptidase inhibitor	0.027
Cpxm2	carboxypeptidase X (M14 family), member 2	0.027
Csf1	colony stimulating factor 1 (macrophage)	0.027
Rab32	RAB32, member RAS oncogene family	0.027
Irak3	interleukin-1 receptor-associated kinase 3	0.024
Il2rg	interleukin 2 receptor, gamma	0.023
Ccr1	chemokine (C-C motif) receptor 1	0.023
Casp3	caspase 3	0.023
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.022
Cdh17	cadherin 17	0.021
Fcgr1a	Fc fragment of IgG, high affinity Ia, receptor (CD64)	0.020
Irs3	insulin receptor substrate 3	0.020
Cmtm2a	CKLF-like MARVEL transmembrane domain containing 2A	0.020
Adam7	ADAM metallopeptidase domain 7	0.019
Lpl	lipoprotein lipase	0.019
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.019
F13a1	coagulation factor XIII, A1 polypeptide	0.019
Grpr	gastrin releasing peptide receptor	0.018
Sele	selectin E	0.018
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.018
Cxcl11	chemokine (C-X-C motif) ligand 11	0.017
Runx1	runt-related transcription factor 1	0.017
Nox4	NADPH oxidase 4	0.017
Adamts4	ADAM metallopeptidase with thrombospondin type 1 motif, 4	0.016
Casp1	caspase 1	0.016
Ch25h	cholesterol 25-hydroxylase	0.015
Il4ra	interleukin 4 receptor, alpha	0.015
Tec	tec protein tyrosine kinase	0.015
Il13ra1	interleukin 13 receptor, alpha 1	0.015
Ccl22	chemokine (C-C motif) ligand 22	0.015
Clec9a	C-type lectin domain family 9, member a	0.015
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.014
Bcl3	B-cell CLL/lymphoma 3	0.014
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.014
Cd44	Cd44 molecule	0.014
C1d	C1D nuclear receptor co-repressor	0.014
Arhgap4	Rho GTPase activating protein 4	0.014
Ccl11	chemokine (C-C motif) ligand 11	0.014	Rat
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.013
Ifi204	interferon activated gene 204	0.013
Ccl6	chemokine (C-C motif) ligand 6	0.013	Rat
Olr1496	olfactory receptor 1496	0.013
Cfi	complement factor I	0.012
Myd88	myeloid differentiation primary response gene 88	0.012	Mouse
Ereg	epiregulin	0.012
Ptpn18	protein tyrosine phosphatase, non-receptor type 18	0.012
Stx11	syntaxin 11	0.012
Il8rb	interleukin 8 receptor, beta	0.012	Rat
Cd40	CD40 molecule, TNF receptor superfamily member 5	0.012
Clec2d	C-type lectin domain family 2, member d	0.012
Ghr	growth hormone receptor	0.012
P2ry14	purinergic receptor P2Y, G-protein coupled, 14	0.012
Ciita	class II, major histocompatibility complex, transactivator	0.011
Adora2a	adenosine A2a receptor	0.011
Fas	Fas (TNF receptor superfamily, member 6)	0.011	Rat
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.011
Ogfrl1	opioid growth factor receptor-like 1	0.011
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.011
Faslg	Fas ligand (TNF superfamily, member 6)	0.010
Ms4a11	membrane-spanning 4-domains, subfamily A, member 11	0.010
Hck	hemopoietic cell kinase	0.010
Tifa	TRAF-interacting protein with forkhead-associated domain	0.010
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.010