IMP

Process View

Rattus norvegicus

6 genes annotated in rat

Multi-species View

regulation of fever generation

GO:0031620

Any process that modulates the rate or extent of fever generation.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of fever generation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of fever generation" (in gray)

Name	Description	Probability	Func Analog Organism
Il1b	interleukin 1 beta	0.999
Ccl2	chemokine (C-C motif) ligand 2	0.981
Ccl3	chemokine (C-C motif) ligand 3	0.980	Rat
Cd14	CD14 molecule	0.941
Il6	interleukin 6	0.889
Ccl4	chemokine (C-C motif) ligand 4	0.873	Rat
Cxcl2	chemokine (C-X-C motif) ligand 2	0.847
Il1a	interleukin 1 alpha	0.833
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.779
Cxcl10	chemokine (C-X-C motif) ligand 10	0.504
Ccl20	chemokine (C-C motif) ligand 20	0.388	Rat
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.386
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.311
Serpine1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.255
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.213	Mouse
Mmp12	matrix metallopeptidase 12	0.209
Gzmb	granzyme B	0.142
Tgm1	transglutaminase 1, K polypeptide	0.132
Neurl3	neuralized homolog 3 (Drosophila)	0.119
Mca32	mast cell antigen 32	0.118
Cd86	CD86 molecule	0.118
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.116
Fosl1	fos-like antigen 1	0.104
Sell	selectin L	0.099
Tfec	transcription factor EC	0.091
Il1r2	interleukin 1 receptor, type II	0.089
Rab20	RAB20, member RAS oncogene family	0.073
Nkg7	natural killer cell group 7 sequence	0.072
Prf1	perforin 1 (pore forming protein)	0.072
Sult2a1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.066
Gzmk	granzyme K	0.053
Ccl7	chemokine (C-C motif) ligand 7	0.052	Rat
Socs3	suppressor of cytokine signaling 3	0.050
Ccl5	chemokine (C-C motif) ligand 5	0.048
Serpinb2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.048
RT1-Bb	RT1 class II, locus Bb	0.047
Xcl1	chemokine (C motif) ligand 1	0.045	Rat
Il2rb	interleukin 2 receptor, beta	0.043
Nr4a3	nuclear receptor subfamily 4, group A, member 3	0.040
Fcn1	ficolin (collagen/fibrinogen domain containing) 1	0.040
Calcrl	calcitonin receptor-like	0.037
Vcan	versican	0.036
Cd44	Cd44 molecule	0.036
Thbd	thrombomodulin	0.035
Il1rn	interleukin 1 receptor antagonist	0.035
Edn1	endothelin 1	0.034
Sele	selectin E	0.034
Adora2a	adenosine A2a receptor	0.033
Ccr1	chemokine (C-C motif) receptor 1	0.033
Ednrb	endothelin receptor type B	0.033
LOC685020	similar to paired immunoglobin-like type 2 receptor alpha	0.033
Hpgds	hematopoietic prostaglandin D synthase	0.032
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.031
Aqp4	aquaporin 4	0.031
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.029
Tlr2	toll-like receptor 2	0.029
Lst1	leukocyte specific transcript 1	0.029
RT1-Ba	RT1 class II, locus Ba	0.028
Reg3b	regenerating islet-derived 3 beta	0.025
Folr2	folate receptor 2 (fetal)	0.025
Mmp3	matrix metallopeptidase 3	0.025
Adamts4	ADAM metallopeptidase with thrombospondin type 1 motif, 4	0.025
Slc15a2	solute carrier family 15 (H+/peptide transporter), member 2	0.024
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, gamma 1	0.023
Ptafr	platelet-activating factor receptor	0.022
Tlr7	toll-like receptor 7	0.021
Rab32	RAB32, member RAS oncogene family	0.021
Tcrb	T-cell receptor beta chain	0.021
Cd247	Cd247 molecule	0.021
Clec9a	C-type lectin domain family 9, member a	0.020
Casp1	caspase 1	0.019
P2ry14	purinergic receptor P2Y, G-protein coupled, 14	0.019
Ptprz1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.019
Ncf4	neutrophil cytosolic factor 4	0.019
Stx11	syntaxin 11	0.018
Cxcl3	chemokine (C-X-C motif) ligand 3	0.017
Egr2	early growth response 2	0.016
Hck	hemopoietic cell kinase	0.016
Ubd	ubiquitin D	0.016
Plscr1	phospholipid scramblase 1	0.015
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.015
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.015
Tfpi2	tissue factor pathway inhibitor 2	0.014
Mgst2	microsomal glutathione S-transferase 2	0.014
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.013
Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	0.013
Plau	plasminogen activator, urokinase	0.013
Mcpt8	mast cell protease 8	0.012
Igsf6	immunoglobulin superfamily, member 6	0.012
C5ar1	complement component 5a receptor 1	0.012
Ripk3	receptor-interacting serine-threonine kinase 3	0.011
Arl5c	ADP-ribosylation factor-like 5C	0.011
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.011
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.011
Fcgr3a	Fc fragment of IgG, low affinity IIIa, receptor	0.011
Tlr4	toll-like receptor 4	0.010
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.010