The network for 'regulation of transcription regulatory region dna binding' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of transcription regulatory region dna binding

Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding.

Drosophila melanogaster
Name Description Probability Func Analog Organism
tim timeless 0.447
per period 0.257
babo baboon 0.073
cry cryptochrome 0.069
Rdl Resistant to dieldrin 0.055
cwo clockwork orange 0.033
fas faint sausage 0.033
Clk Clock 0.030
Plc21C Phospholipase C at 21C 0.029
byn brachyenteron 0.026
slo slowpoke 0.026
pdm2 POU domain protein 2 0.025
blot bloated tubules 0.024
CG12424 CG12424 gene product from transcript CG12424-RC 0.022
ems empty spiracles 0.021
myoglianin CG1838 gene product from transcript CG1838-RD 0.019
Elongin-C Elongin C 0.019
tin tinman 0.019
htl heartless 0.019
CG3776 CG3776 gene product from transcript CG3776-RA 0.018
Rpn2 CG11888 gene product from transcript CG11888-RA 0.017
Pdf Pigment-dispersing factor 0.017
Dat Dopamine N acetyltransferase 0.017
iav inactive 0.017
qvr quiver 0.016
Pdp1 PAR-domain protein 1 0.016
l(1)G0045 lethal (1) G0045 0.016
repo reversed polarity 0.015
EndoGI Endonuclease G inhibitor 0.015
Bre1 CG10542 gene product from transcript CG10542-RA 0.014
Ilp5 Insulin-like peptide 5 0.014
Adgf-A Adenosine deaminase-related growth factor A 0.013
HLH54F CG5005 gene product from transcript CG5005-RA 0.013
prd paired 0.012
klg klingon 0.012
CG4857 CG4857 gene product from transcript CG4857-RD 0.012
Hand CG18144 gene product from transcript CG18144-RA 0.011
RagA CG11968 gene product from transcript CG11968-RA 0.010
l(2)k14505 lethal (2) k14505 0.010
lab labial 0.010
Jarid2 CG3654 gene product from transcript CG3654-RD 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
ruvb-1 Protein RUVB-1 0.019
F21D5.2 Protein F21D5.2 0.019
ruvb-2 Protein RUVB-2 0.014
ran-1 Protein RAN-1 0.013
T02G5.12 Protein T02G5.12 0.012
ZC155.4 Protein ZC155.4 0.011
eif-3.I Protein EIF-3.I 0.011
hke-4.1 Protein HKE-4.1 0.011
tac-1 Protein TAC-1 0.010
pri-2 Protein PRI-2 0.010
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Danio rerio
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
ZNF43 zinc finger protein 43 0.970
TAL1 T-cell acute lymphocytic leukemia 1 0.856
ZNF273 zinc finger protein 273 0.809
ZNF253 zinc finger protein 253 0.771
ZNF675 zinc finger protein 675 0.660
TRAF2 TNF receptor-associated factor 2 0.495
SKIL SKI-like oncogene 0.415
SMAD3 SMAD family member 3 0.341
ZNF85 zinc finger protein 85 0.267
ZNF708 zinc finger protein 708 0.255
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.245
RIPK2 receptor-interacting serine-threonine kinase 2 0.217
ZNF680 zinc finger protein 680 0.180
ZNF117 zinc finger protein 117 0.173
SETD8 SET domain containing (lysine methyltransferase) 8 0.159
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.136
ZNF430 zinc finger protein 430 0.134
SMAD9 SMAD family member 9 0.134
ZNF93 zinc finger protein 93 0.124
ZNF254 zinc finger protein 254 0.123
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.119
HIST2H3C histone cluster 2, H3c 0.117
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) 0.095
NCOR2 nuclear receptor corepressor 2 0.093
ZMYND11 zinc finger, MYND-type containing 11 0.088
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.087
MAFA v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) 0.083
TRAF3 TNF receptor-associated factor 3 0.082
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.066
ZNF91 zinc finger protein 91 0.066
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 0.058
PIAS4 protein inhibitor of activated STAT, 4 0.053
GATA2 GATA binding protein 2 0.050
CD40 CD40 molecule, TNF receptor superfamily member 5 0.048
RBBP4 retinoblastoma binding protein 4 0.036
ZNF512B zinc finger protein 512B 0.036
TGFBR1 transforming growth factor, beta receptor 1 0.036
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.034
ZNF107 zinc finger protein 107 0.032
ZNF682 zinc finger protein 682 0.030
TRADD TNFRSF1A-associated via death domain 0.029
ZNF92 zinc finger protein 92 0.028
TBX5 T-box 5 0.027
NUMBL numb homolog (Drosophila)-like 0.025
HTT huntingtin 0.024
KLF13 Kruppel-like factor 13 0.024
ENG endoglin 0.023
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.021
TRAF1 TNF receptor-associated factor 1 0.021
BIRC3 baculoviral IAP repeat containing 3 0.020
PSEN2 presenilin 2 (Alzheimer disease 4) 0.020
MSX1 msh homeobox 1 0.019
HDAC1 histone deacetylase 1 0.018
RUNX1 runt-related transcription factor 1 0.017
MDFI MyoD family inhibitor 0.015
ANXA7 annexin A7 0.015
SOD1 superoxide dismutase 1, soluble 0.014
TRAF6 TNF receptor-associated factor 6 0.014
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.014
HAND2 heart and neural crest derivatives expressed 2 0.013
CXXC5 CXXC finger protein 5 0.013
MSX2 msh homeobox 2 0.013
TRAF5 TNF receptor-associated factor 5 0.013
CIAPIN1 cytokine induced apoptosis inhibitor 1 0.013
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.012
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.012
SMAD7 SMAD family member 7 0.012
ING2 inhibitor of growth family, member 2 0.011
HOXB9 homeobox B9 0.010
UBQLN4 ubiquilin 4 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Gata4 GATA binding protein 4 0.943
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.721
Otx2 orthodenticle homolog 2 (Drosophila) 0.696
Pitx2 paired-like homeodomain transcription factor 2 0.687
Per2 period homolog 2 (Drosophila) 0.622
Hand1 heart and neural crest derivatives expressed transcript 1 0.581
Per1 period homolog 1 (Drosophila) 0.507
Cry2 cryptochrome 2 (photolyase-like) 0.300
Fgf8 fibroblast growth factor 8 0.286
Pax2 paired box gene 2 0.188
Gata6 GATA binding protein 6 0.182
Lhx3 LIM homeobox protein 3 0.172
Hand2 heart and neural crest derivatives expressed transcript 2 0.171
Shh sonic hedgehog 0.169
E2f1 E2F transcription factor 1 0.120
Pax6 paired box gene 6 0.101
Zfpm2 zinc finger protein, multitype 2 0.098
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.090
Emx2 empty spiracles homolog 2 (Drosophila) 0.073
Pou4f2 POU domain, class 4, transcription factor 2 0.065
Hes5 hairy and enhancer of split 5 (Drosophila) 0.057
Lhx9 LIM homeobox protein 9 0.057
Pax3 paired box gene 3 0.056
Hdac1 histone deacetylase 1 0.055
Tal1 T-cell acute lymphocytic leukemia 1 0.055
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.054
Foxc2 forkhead box C2 0.052
Lmx1a LIM homeobox transcription factor 1 alpha 0.049
Isl1 ISL1 transcription factor, LIM/homeodomain 0.048
Ntf3 neurotrophin 3 0.048
En2 engrailed 2 0.048
Wt1 Wilms tumor 1 homolog 0.046
Msx1 homeobox, msh-like 1 0.045
Lef1 lymphoid enhancer binding factor 1 0.039
Tgfb2 transforming growth factor, beta 2 0.036
Snai1 snail homolog 1 (Drosophila) 0.036
Emx1 empty spiracles homolog 1 (Drosophila) 0.036
En1 engrailed 1 0.033
Neurog2 neurogenin 2 0.032
Tbx3 T-box 3 0.031
Insm1 insulinoma-associated 1 0.031
Usp2 ubiquitin specific peptidase 2 0.030
Jag1 jagged 1 0.030
Bnc1 basonuclin 1 0.029
Gbx2 gastrulation brain homeobox 2 0.026
Ebf3 early B-cell factor 3 0.026
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.025
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.025
Mab21l2 mab-21-like 2 (C. elegans) 0.025
Sox2 SRY-box containing gene 2 0.024
Coro1b coronin, actin binding protein 1B 0.022
Tbx20 T-box 20 0.019
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.018
Prox1 prospero-related homeobox 1 0.018
0610031J06Rik RIKEN cDNA 0610031J06 gene 0.018
Gdnf glial cell line derived neurotrophic factor 0.018
Socs1 suppressor of cytokine signaling 1 0.017
Akr1a4 aldo-keto reductase family 1, member A4 (aldehyde reductase) 0.017
Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 0.016
Tef thyrotroph embryonic factor 0.016
Pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.016
Nr2e1 nuclear receptor subfamily 2, group E, member 1 0.016
Foxn1 forkhead box N1 0.016
Sox4 SRY-box containing gene 4 0.015
Srrm4 serine/arginine repetitive matrix 4 0.015
Ldb2 LIM domain binding 2 0.015
Rxra retinoid X receptor alpha 0.015
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.015
Foxf1a forkhead box F1a 0.015
Nkx1-2 NK1 transcription factor related, locus 2 (Drosophila) 0.014
Ighmbp2 immunoglobulin mu binding protein 2 0.014
Onecut1 one cut domain, family member 1 0.013
Sox7 SRY-box containing gene 7 0.013
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.013
Ufc1 ubiquitin-fold modifier conjugating enzyme 1 0.012
Eya1 eyes absent 1 homolog (Drosophila) 0.012
Hoxa11 homeobox A11 0.012
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.012
Chmp2a chromatin modifying protein 2A 0.012
Nos3 nitric oxide synthase 3, endothelial cell 0.012
Ptf1a pancreas specific transcription factor, 1a 0.012
Epha3 Eph receptor A3 0.011
Slc12a5 solute carrier family 12, member 5 0.011
Hoxc8 homeobox C8 0.011
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.011
Klf3 Kruppel-like factor 3 (basic) 0.011
Rnh1 ribonuclease/angiogenin inhibitor 1 0.010
Nhlh1 nescient helix loop helix 1 0.010
Lhx1 LIM homeobox protein 1 0.010
Dpysl4 dihydropyrimidinase-like 4 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
Sox18 SRY (sex determining region Y)-box 18 0.100
Acot12 acyl-CoA thioesterase 12 0.092
Rpl22l1 ribosomal protein L22 like 1 0.082
Gpr116 G protein-coupled receptor 116 0.076
Cdh5 cadherin 5 0.075
Foxe1 forkhead box E1 (thyroid transcription factor 2) 0.074
Sox7 SRY (sex determining region Y)-box 7 0.073
Ran RAN, member RAS oncogene family 0.053
Epn1 Epsin 1 0.053
Il1r1 interleukin 1 receptor, type I 0.051
Nos3 nitric oxide synthase 3, endothelial cell 0.046
Emcn endomucin 0.046
Edn2 endothelin 2 0.042
Fgf1 fibroblast growth factor 1 0.041
P2ry4 pyrimidinergic receptor P2Y, G-protein coupled, 4 0.035
Mstn myostatin 0.035
Ptprh protein tyrosine phosphatase, receptor type, H 0.033
Dao D-amino-acid oxidase 0.032
Crybb1 crystallin, beta B1 0.031
Gata2 GATA binding protein 2 0.030
Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 0.029
Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 0.029
Tcfe2a transcription factor E2a 0.028
Olr59 olfactory receptor 59 0.028
Psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 0.028
Foxe3 forkhead box E3 0.027
Acox2 acyl-Coenzyme A oxidase 2, branched chain 0.026
Prlr prolactin receptor 0.026
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.025
Actr10 actin-related protein 10 homolog (S. cerevisiae) 0.024
Ppp1r3b protein phosphatase 1, regulatory (inhibitor) subunit 3B 0.024
Hr hairless 0.023
Acox3 acyl-Coenzyme A oxidase 3, pristanoyl 0.023
Ncaph2 non-SMC condensin II complex, subunit H2 0.022
Acacb acetyl-Coenzyme A carboxylase beta 0.022
Psbpc1 prostatic steroid binding protein C1 0.022
Akp3 alkaline phosphatase 3, intestine, not Mn requiring 0.022
Ralgds ral guanine nucleotide dissociation stimulator 0.022
Aqp2 aquaporin 2 (collecting duct) 0.022
Thrb thyroid hormone receptor beta 0.022
Ppara peroxisome proliferator activated receptor alpha 0.022
Fkbp3 FK506 binding protein 3 0.022
Arhgef15 Rho guanine nucleotide exchange factor (GEF) 15 0.021
Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 0.021
Tp53 tumor protein p53 0.021
Gabrr1 gamma-aminobutyric acid (GABA) receptor, rho 1 0.021
Oaz3 ornithine decarboxylase antizyme 3 0.021
Slc9a4 solute carrier family 9 (sodium/hydrogen exchanger), member 4 0.021
Foxd3 forkhead box D3 0.020
Mef2d myocyte enhancer factor 2D 0.020
Dhdpsl dihydrodipicolinate synthase-like, mitochondrial 0.020
Epas1 endothelial PAS domain protein 1 0.020
Slc26a1 solute carrier family 26 (sulfate transporter), member 1 0.020
Neu3 sialidase 3 (membrane sialidase) 0.019
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.019
Eif1ay eukaryotic translation initiation factor 1A, Y-linked 0.019
Tpo thyroid peroxidase 0.019
Eng endoglin 0.019
Tpcn1 two pore segment channel 1 0.018
Pax6 paired box 6 0.018
Klf9 Kruppel-like factor 9 0.018
Gucy2e guanylate cyclase 2E 0.018
Hipk3 homeodomain interacting protein kinase 3 0.018
Hes5 hairy and enhancer of split 5 (Drosophila) 0.018
Aspg asparaginase homolog (S. cerevisiae) 0.018
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.017
Capn1 calpain 1 0.017
Ppil3 peptidylprolyl isomerase (cyclophilin)-like 3 0.017
Gulo gulonolactone (L-) oxidase 0.017
Slc9a3 solute carrier family 9 (sodium/hydrogen exchanger), member 3 0.017
Wasf2 WAS protein family, member 2 0.016
Safb scaffold attachment factor B 0.016
Pyy peptide YY (mapped) 0.016
Adrb1 adrenergic, beta-1-, receptor 0.016
Hnf4a hepatocyte nuclear factor 4, alpha 0.016
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.016
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.016
Pvrl4 poliovirus receptor-related 4 0.016
Pou3f2 POU class 3 homeobox 2 0.016
Cda cytidine deaminase 0.016
Elavl4 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) 0.016
Cyyr1 cysteine/tyrosine-rich 1 0.016
Prkcg protein kinase C, gamma 0.015
Svs1 seminal vesicle secretory protein 1 0.015
Tceb1 transcription elongation factor B (SIII), polypeptide 1 0.015
Gcgr glucagon receptor 0.015
Trib1 tribbles homolog 1 (Drosophila) 0.015
Apoa5 apolipoprotein A-V 0.015
Sdcbp2 syndecan binding protein (syntenin) 2 0.015
Nlrp6 NLR family, pyrin domain containing 6 0.015
Rtcd1 RNA terminal phosphate cyclase domain 1 0.015
Naaladl1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.015
Fcer2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.015
Gse1 genetic suppressor element 1 0.015
Defb1 defensin beta 1 0.015
Slc23a1 solute carrier family 23 (nucleobase transporters), member 1 0.015
Lrg1 leucine-rich alpha-2-glycoprotein 1 0.015
Psap prosaposin 0.014
Myo10 myosin X 0.014
Lemd2 LEM domain containing 2 0.014
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism