The network for 'gene looping' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

gene looping

The formation and maintenance of DNA loops that juxtapose sequentially separated regions of RNA polymerase II-transcribed genes.

Homo sapiens
Name Description Probability Func Analog Organism
MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) 0.062
UBC ubiquitin C 0.030
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.029
SRSF1 serine/arginine-rich splicing factor 1 0.029
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.028
MCM7 minichromosome maintenance complex component 7 0.028
TOPBP1 topoisomerase (DNA) II binding protein 1 0.027
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.026
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0.022
MRPL3 mitochondrial ribosomal protein L3 0.017
SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.017
BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) 0.016
CAND1 cullin-associated and neddylation-dissociated 1 0.016
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 0.015
SERBP1 SERPINE1 mRNA binding protein 1 0.015
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.014
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.014
HAT1 histone acetyltransferase 1 0.013
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 0.013
RUVBL2 RuvB-like 2 (E. coli) 0.012
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.011
SEH1L SEH1-like (S. cerevisiae) 0.010
VBP1 von Hippel-Lindau binding protein 1 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
N Notch 0.032
Dl Delta 0.029
exd extradenticle 0.015
Aos1 CG12276 gene product from transcript CG12276-RA 0.011
arm armadillo 0.011
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Mus musculus
Name Description Probability Func Analog Organism
Gata4 GATA binding protein 4 1.000
Gata6 GATA binding protein 6 0.984
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.983
Rxra retinoid X receptor alpha 0.980
Jag1 jagged 1 0.917
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.643
Zfpm2 zinc finger protein, multitype 2 0.619
Gata5 GATA binding protein 5 0.600
Pitx2 paired-like homeodomain transcription factor 2 0.567
Hoxa1 homeobox A1 0.554
Klf3 Kruppel-like factor 3 (basic) 0.442
Tal1 T-cell acute lymphocytic leukemia 1 0.289
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.249
Tgfb2 transforming growth factor, beta 2 0.201
Ppara peroxisome proliferator activated receptor alpha 0.200
Vegfa vascular endothelial growth factor A 0.109
Tbx3 T-box 3 0.102
Smad6 MAD homolog 6 (Drosophila) 0.096
Hand2 heart and neural crest derivatives expressed transcript 2 0.090
Notch1 Notch gene homolog 1 (Drosophila) 0.087
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.080
Fgf8 fibroblast growth factor 8 0.079
Mesp1 mesoderm posterior 1 0.070
P2rx1 purinergic receptor P2X, ligand-gated ion channel, 1 0.065
Ntf3 neurotrophin 3 0.061
Nos3 nitric oxide synthase 3, endothelial cell 0.059
Tead3 TEA domain family member 3 0.055
Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.053
Pax2 paired box gene 2 0.045
Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) 0.044
Lat linker for activation of T cells 0.039
Foxf1a forkhead box F1a 0.039
Gata1 GATA binding protein 1 0.037
Rarg retinoic acid receptor, gamma 0.035
Ptpn14 protein tyrosine phosphatase, non-receptor type 14 0.031
Gfi1b growth factor independent 1B 0.029
Egfr epidermal growth factor receptor 0.029
S1pr2 sphingosine-1-phosphate receptor 2 0.022
Tbx2 T-box 2 0.021
Slc38a5 solute carrier family 38, member 5 0.020
Efnb2 ephrin B2 0.019
Zfpm1 zinc finger protein, multitype 1 0.019
Pold2 polymerase (DNA directed), delta 2, regulatory subunit 0.019
Wt1 Wilms tumor 1 homolog 0.019
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.019
Hey1 hairy/enhancer-of-split related with YRPW motif 1 0.018
Sox7 SRY-box containing gene 7 0.017
Epha1 Eph receptor A1 0.017
Bnc1 basonuclin 1 0.017
Gja1 gap junction protein, alpha 1 0.016
Ruvbl1 RuvB-like protein 1 0.016
Myl7 myosin, light polypeptide 7, regulatory 0.016
Six5 sine oculis-related homeobox 5 homolog (Drosophila) 0.016
Efnb1 ephrin B1 0.015
Myb myeloblastosis oncogene 0.015
Chd7 chromodomain helicase DNA binding protein 7 0.015
Carm1 coactivator-associated arginine methyltransferase 1 0.015
Dll1 delta-like 1 (Drosophila) 0.015
Ush1g Usher syndrome 1G homolog (human) 0.014
Snai1 snail homolog 1 (Drosophila) 0.014
Hoxc8 homeobox C8 0.014
Epor erythropoietin receptor 0.014
Slc34a2 solute carrier family 34 (sodium phosphate), member 2 0.013
Slc4a1 solute carrier family 4 (anion exchanger), member 1 0.012
Klf1 Kruppel-like factor 1 (erythroid) 0.012
Ar androgen receptor 0.012
Gpr97 G protein-coupled receptor 97 0.012
Axin2 axin2 0.011
Tbxa2r thromboxane A2 receptor 0.011
Foxa3 forkhead box A3 0.011
Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 0.011
Nynrin NYN domain and retroviral integrase containing 0.011
Idua iduronidase, alpha-L- 0.010
Hoxb4 homeobox B4 0.010
Bmp4 bone morphogenetic protein 4 0.010
Gypa glycophorin A 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism