The network for 'sulfur amino acid metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

sulfur amino acid metabolic process

The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine.

Homo sapiens
Name Description Probability Func Analog Organism
GCLC glutamate-cysteine ligase, catalytic subunit 0.436
GCLM glutamate-cysteine ligase, modifier subunit 0.276
RAB10 RAB10, member RAS oncogene family 0.238
LPHN1 latrophilin 1 0.080
ARHGAP22 Rho GTPase activating protein 22 0.070
TUBB2B tubulin, beta 2B 0.053
LTBP4 latent transforming growth factor beta binding protein 4 0.049
MEGF8 multiple EGF-like-domains 8 0.038
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 0.036
LNX1 ligand of numb-protein X 1 0.035
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) 0.030
BZRAP1 benzodiazapine receptor (peripheral) associated protein 1 0.028
PDHX pyruvate dehydrogenase complex, component X 0.028
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.026
AUH AU RNA binding protein/enoyl-CoA hydratase 0.021
EIF3J eukaryotic translation initiation factor 3, subunit J 0.021
PGRMC2 progesterone receptor membrane component 2 0.020
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 0.017
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 0.017
GFI1B growth factor independent 1B transcription repressor 0.017
SRSF5 serine/arginine-rich splicing factor 5 0.016
NARS asparaginyl-tRNA synthetase 0.016
SNF8 SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) 0.016
ANAPC10 anaphase promoting complex subunit 10 0.016
ISOC1 isochorismatase domain containing 1 0.015
TMEM106B transmembrane protein 106B 0.015
PHKB phosphorylase kinase, beta 0.015
SRSF4 serine/arginine-rich splicing factor 4 0.015
SYNJ2BP synaptojanin 2 binding protein 0.014
FAM8A1 family with sequence similarity 8, member A1 0.014
PHYH phytanoyl-CoA 2-hydroxylase 0.014
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.013
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type 0.013
PRPS2 phosphoribosyl pyrophosphate synthetase 2 0.013
TMEM184C transmembrane protein 184C 0.013
LACTB2 lactamase, beta 2 0.013
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.013
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.013
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 0.013
SRRM4 serine/arginine repetitive matrix 4 0.012
MRPL19 mitochondrial ribosomal protein L19 0.012
MEGF6 multiple EGF-like-domains 6 0.011
EIF4E eukaryotic translation initiation factor 4E 0.011
KLHDC2 kelch domain containing 2 0.011
TIFA TRAF-interacting protein with forkhead-associated domain 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
mthf-1 Protein MTHF-1 0.032
mtrr-1 Protein MTRR-1 0.032
metr-1 Protein METR-1 0.017
ldh-1 Protein LDH-1 0.017
hsp-4 Protein HSP-4 0.014
sams-4 Protein SAMS-4 0.012
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Gclm glutamate-cysteine ligase, modifier subunit 0.665
Gclc glutamate-cysteine ligase, catalytic subunit 0.637
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.253
Cacnb2 calcium channel, voltage-dependent, beta 2 subunit 0.169
Slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 0.099
Ryr1 ryanodine receptor 1, skeletal muscle 0.088
Bsn bassoon 0.081
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.059
Cacnb4 calcium channel, voltage-dependent, beta 4 subunit 0.053
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.047
Thrb thyroid hormone receptor beta 0.041
Kifc2 kinesin family member C2 0.036
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.033
Sfxn1 sideroflexin 1 0.021
Stx1a syntaxin 1A (brain) 0.018
Ivd isovaleryl coenzyme A dehydrogenase 0.018
Adam23 a disintegrin and metallopeptidase domain 23 0.018
Ahsg alpha-2-HS-glycoprotein 0.015
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 0.014
Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 0.014
AI118078 expressed sequence AI118078 0.012
Acadm acyl-Coenzyme A dehydrogenase, medium chain 0.012
Cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.011
Nos1 nitric oxide synthase 1, neuronal 0.011
Tg thyroglobulin 0.011
Chrna9 cholinergic receptor, nicotinic, alpha polypeptide 9 0.011
Dbt dihydrolipoamide branched chain transacylase E2 0.011
Abcb9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 0.011
Rnf112 ring finger protein 112 0.010
Kif5c kinesin family member 5C 0.010
Il16 interleukin 16 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
Freq frequenin homolog (Drosophila) 0.315
Aadat aminoadipate aminotransferase 0.183
Rdh2 retinol dehydrogenase 2 0.155
Sult1a1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.112
Dhfr dihydrofolate reductase 0.103
LOC362855 P55 0.053
Ppif peptidylprolyl isomerase F 0.053
Dlc1 deleted in liver cancer 1 0.050
Dmgdh dimethylglycine dehydrogenase 0.049
Guca2a guanylate cyclase activator 2a (guanylin) 0.048
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.048
Gata4 GATA binding protein 4 0.047
Acmsd aminocarboxymuconate semialdehyde decarboxylase 0.044
Tat tyrosine aminotransferase 0.042
Aqp7 aquaporin 7 0.040
Pah phenylalanine hydroxylase 0.039
Itih3 inter-alpha trypsin inhibitor, heavy chain 3 0.038
Ass1 argininosuccinate synthetase 1 0.038
Ucn2 urocortin 2 0.037
Ddx17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 0.036
Dpp4 dipeptidylpeptidase 4 0.036
Sfxn1 sideroflexin 1 0.035
Fam35a family with sequence similarity 35, member A 0.034
Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) 0.033
LOC259245 alpha-2u globulin PGCL5 0.033
Sardh sarcosine dehydrogenase 0.032
Rpl4 ribosomal protein L4 0.031
Eif4h eukaryotic translation initiation factor 4H 0.030
Gulo gulonolactone (L-) oxidase 0.030
Fmo3 flavin containing monooxygenase 3 0.028
Pex1 peroxisomal biogenesis factor 1 0.028
Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.027
Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 0.026
Ung uracil-DNA glycosylase 0.026
Gls glutaminase 0.026
Fabp1 fatty acid binding protein 1, liver 0.026
Hebp1 heme binding protein 1 0.024
Ugt2b36 UDP glucuronosyltransferase 2 family, polypeptide B36 0.023
Hacl1 2-hydroxyacyl-CoA lyase 1 0.022
Arl8b ADP-ribosylation factor-like 8B 0.022
Cth cystathionase (cystathionine gamma-lyase) 0.022
Epha7 Eph receptor A7 0.021
Clcn2 chloride channel 2 0.021
Fmo1 flavin containing monooxygenase 1 0.021
Hrsp12 heat-responsive protein 12 0.020
Gc group specific component 0.020
Acsm3 acyl-CoA synthetase medium-chain family member 3 0.019
Nf2 neurofibromin 2 (merlin) 0.019
Fas Fas (TNF receptor superfamily, member 6) 0.019
Sema3a sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.019
Gnmt glycine N-methyltransferase 0.018
Aldh9a1 aldehyde dehydrogenase 9 family, member A1 0.018
Mro maestro 0.018
Asl argininosuccinate lyase 0.018
Mat1a methionine adenosyltransferase I, alpha 0.018
Rnf207 ring finger protein 207 0.017
Ube2i ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.017
Car5a carbonic anhydrase 5a, mitochondrial 0.017
Mme membrane metallo-endopeptidase 0.017
Pawr PRKC, apoptosis, WT1, regulator 0.016
Hgf hepatocyte growth factor 0.016
LOC683801 similar to zinc finger protein 740 0.016
Agtr1a angiotensin II receptor, type 1a 0.016
LOC679368 similar to carboxylesterase 5 0.015
Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 0.015
Ftcd formiminotransferase cyclodeaminase 0.015
Tollip toll interacting protein 0.015
Kcnb2 potassium voltage gated channel, Shab-related subfamily, member 2 0.015
Acacb acetyl-Coenzyme A carboxylase beta 0.015
Pgam1 phosphoglycerate mutase 1 (brain) 0.015
Baat bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) 0.015
Cspg5 chondroitin sulfate proteoglycan 5 0.015
Slc22a6 solute carrier family 22 (organic anion transporter), member 6 0.015
LOC680367 similar to Urinary protein 3 precursor (RUP-3) 0.015
Acly ATP citrate lyase 0.015
Ttpa tocopherol (alpha) transfer protein 0.015
Tmem144 transmembrane protein 144 0.014
Hpd 4-hydroxyphenylpyruvate dioxygenase 0.014
St6galnac3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.014
Gata6 GATA binding protein 6 0.014
Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 0.014
Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 0.014
Mertk c-mer proto-oncogene tyrosine kinase 0.014
Il1r1 interleukin 1 receptor, type I 0.014
Hpgd hydroxyprostaglandin dehydrogenase 15 (NAD) 0.014
Srpx sushi-repeat-containing protein, X-linked 0.014
App amyloid beta (A4) precursor protein 0.014
Gpt glutamic-pyruvate transaminase (alanine aminotransferase) 0.013
Aktip AKT interacting protein 0.013
Xpnpep2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 0.013
Bhmt betaine-homocysteine methyltransferase 0.013
Adrb1 adrenergic, beta-1-, receptor 0.013
Klks3 kallikrein, submaxillary gland S3 0.013
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.013
Apoc4 apolipoprotein C-IV 0.013
Figf c-fos induced growth factor 0.013
Reep6 receptor accessory protein 6 0.013
Thrsp thyroid hormone responsive 0.013
Rnf19a ring finger protein 19A 0.012
Dpyd dihydropyrimidine dehydrogenase 0.012
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
MET14 Met14p 0.991
MET6 Met6p 0.966
MET3 Met3p 0.944
MET10 Met10p 0.908
MET28 Met28p 0.853
MET5 Met5p 0.833
SER33 Ser33p 0.829
MET17 Met17p 0.722
MET13 Met13p 0.709
MET16 Met16p 0.695
MET1 Met1p 0.663
THR4 Thr4p 0.647
MET30 Met30p 0.619
SUL2 Sul2p 0.571
MET4 Met4p 0.558
STR3 Str3p 0.536
ARO9 Aro9p 0.475
SAM2 Sam2p 0.374
MET2 Met2p 0.331
MET32 Met32p 0.233
MDE1 Mde1p 0.221
MET12 Met12p 0.186
YHR112C hypothetical protein 0.161
BNA3 Bna3p 0.134
ARO1 Aro1p 0.133
ORT1 Ort1p 0.131
REE1 Ree1p 0.128
MET8 Met8p 0.114
TRP3 Trp3p 0.107
ALD5 Ald5p 0.107
MUP3 Mup3p 0.103
RMD6 Rmd6p 0.098
YOR302W hypothetical protein 0.092
GRX8 Grx8p 0.092
GUS1 Gus1p 0.086
UTR1 Utr1p 0.083
NCE103 Nce103p 0.082
DUG1 Dug1p 0.080
KAP104 Kap104p 0.079
SER3 Ser3p 0.077
PHO11 Pho11p 0.066
ARG8 Arg8p 0.063
SPE3 Spe3p 0.062
ARG5,6 Arg5,6p 0.062
BIT61 Bit61p 0.059
YHB1 Yhb1p 0.057
YMC1 Ymc1p 0.056
SER1 Ser1p 0.056
ERV46 Erv46p 0.055
PRS2 Prs2p 0.053
ARG3 Arg3p 0.052
OPT1 Opt1p 0.052
CPA1 Cpa1p 0.052
PCL5 Pcl5p 0.051
MHT1 Mht1p 0.048
YMR130W hypothetical protein 0.048
TSC3 Tsc3p 0.045
AMD2 Amd2p 0.044
ILV2 Ilv2p 0.044
YOR021C hypothetical protein 0.042
YPL199C hypothetical protein 0.040
ACC1 Acc1p 0.039
YLR264C-A hypothetical protein 0.039
SEO1 Seo1p 0.038
GGC1 Ggc1p 0.038
ASN1 Asn1p 0.037
ICY2 Icy2p 0.037
YLR162W hypothetical protein 0.037
SRD1 Srd1p 0.037
PTR2 Ptr2p 0.037
ARP10 Arp10p 0.037
DLD3 Dld3p 0.037
LEU2 Leu2p 0.035
SUL1 Sul1p 0.035
YOL014W hypothetical protein 0.035
AIM27 Aim27p 0.035
URA1 Ura1p 0.035
FUI1 Fui1p 0.034
ENA5 Ena5p 0.034
NTG1 Ntg1p 0.033
SFH5 Sfh5p 0.033
MXR1 Mxr1p 0.033
SAM3 Sam3p 0.033
YMR321C hypothetical protein 0.033
MER1 Mer1p 0.032
BNA1 Bna1p 0.032
YOL038C-A hypothetical protein 0.032
YJR111C hypothetical protein 0.032
MET22 Met22p 0.032
URA3 Ura3p 0.031
FIT2 Fit2p 0.031
HOR2 Hor2p 0.030
YLR179C hypothetical protein 0.030
MMP1 Mmp1p 0.030
NUT2 Nut2p 0.030
HOM3 Hom3p 0.029
ADH6 Adh6p 0.029
ASN2 Asn2p 0.029
GSH1 Gsh1p 0.029
ADH2 Adh2p 0.029