IMP
Process View
The network for 'response to high density lipoprotein particle' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
response to high density lipoprotein particle
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| SNX33 | sorting nexin 33 | 0.463 | |
| ABI2 | abl-interactor 2 | 0.438 | |
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.095 | |
| CCR5 | chemokine (C-C motif) receptor 5 | 0.090 | |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.071 | |
| SH3D19 | SH3 domain containing 19 | 0.028 | |
| SH3PXD2A | SH3 and PX domains 2A | 0.027 | |
| SNX9 | sorting nexin 9 | 0.027 | |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 0.024 | |
| NPHP1 | nephronophthisis 1 (juvenile) | 0.016 | |
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.014 | |
| STC2 | stanniocalcin 2 | 0.013 | |
| LCK | lymphocyte-specific protein tyrosine kinase | 0.013 | |
| WASL | Wiskott-Aldrich syndrome-like | 0.011 | |
| HCK | hemopoietic cell kinase | 0.011 | |
| REV3L | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 0.011 | |
| CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 0.011 |
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Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Il1b | interleukin 1 beta | 0.982 | |
| Cd14 | CD14 molecule | 0.965 | |
| Cxcl1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.868 | |
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.860 | |
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.797 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.772 | |
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.655 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.624 | |
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.583 | |
| Il6 | interleukin 6 | 0.514 | |
| Olr1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.490 | |
| Gzmb | granzyme B | 0.297 | |
| Timp1 | TIMP metallopeptidase inhibitor 1 | 0.210 | |
| Cd44 | Cd44 molecule | 0.207 | |
| Gzmk | granzyme K | 0.207 | |
| Serpine1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.194 | |
| Reg3b | regenerating islet-derived 3 beta | 0.181 | |
| Il1r2 | interleukin 1 receptor, type II | 0.143 | |
| Top2a | topoisomerase (DNA) II alpha | 0.139 | |
| Bcl2a1d | B-cell leukemia/lymphoma 2 related protein A1d | 0.126 | |
| Hmox1 | heme oxygenase (decycling) 1 | 0.118 | |
| Mmp12 | matrix metallopeptidase 12 | 0.109 | |
| Plek | pleckstrin | 0.107 | |
| Rgs1 | regulator of G-protein signaling 1 | 0.106 | |
| Atf3 | activating transcription factor 3 | 0.098 | |
| Ccl7 | chemokine (C-C motif) ligand 7 | 0.087 | |
| Prf1 | perforin 1 (pore forming protein) | 0.084 | |
| Igsf6 | immunoglobulin superfamily, member 6 | 0.082 | |
| Mmp3 | matrix metallopeptidase 3 | 0.080 | |
| Icam1 | intercellular adhesion molecule 1 | 0.079 | |
| Il1a | interleukin 1 alpha | 0.073 | |
| Xcl1 | chemokine (C motif) ligand 1 | 0.067 | |
| Jak2 | Janus kinase 2 | 0.067 | |
| Neurl3 | neuralized homolog 3 (Drosophila) | 0.065 | |
| Tfpi2 | tissue factor pathway inhibitor 2 | 0.063 | |
| Pla2g4a | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.063 | |
| Acap1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 | 0.059 | |
| Stx11 | syntaxin 11 | 0.059 | |
| Ier3 | immediate early response 3 | 0.053 | |
| Runx1 | runt-related transcription factor 1 | 0.053 | |
| Il2rb | interleukin 2 receptor, beta | 0.051 | |
| Plaur | plasminogen activator, urokinase receptor | 0.048 | |
| Litaf | lipopolysaccharide-induced TNF factor | 0.048 | |
| Nkg7 | natural killer cell group 7 sequence | 0.044 | |
| Ch25h | cholesterol 25-hydroxylase | 0.040 | |
| Cmtm6 | CKLF-like MARVEL transmembrane domain containing 6 | 0.039 | |
| Tlr2 | toll-like receptor 2 | 0.038 | |
| Iqgap1 | IQ motif containing GTPase activating protein 1 | 0.037 | |
| Fcn1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.037 | |
| Sele | selectin E | 0.036 | |
| Rhoj | ras homolog gene family, member J | 0.035 | |
| Serpinb2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.030 | |
| Steap1 | six transmembrane epithelial antigen of the prostate 1 | 0.028 | |
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.028 | |
| Tnf | tumor necrosis factor (TNF superfamily, member 2) | 0.028 | |
| Adamts4 | ADAM metallopeptidase with thrombospondin type 1 motif, 4 | 0.027 | |
| Cd86 | CD86 molecule | 0.025 | |
| Plau | plasminogen activator, urokinase | 0.025 | |
| Myc | myelocytomatosis oncogene | 0.024 | |
| Ripk3 | receptor-interacting serine-threonine kinase 3 | 0.024 | |
| Ccl5 | chemokine (C-C motif) ligand 5 | 0.023 | |
| P2ry14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.023 | |
| Mgst2 | microsomal glutathione S-transferase 2 | 0.022 | |
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.022 | |
| LOC685020 | similar to paired immunoglobin-like type 2 receptor alpha | 0.021 | |
| Pla2g2a | phospholipase A2, group IIA (platelets, synovial fluid) | 0.021 | |
| Vcan | versican | 0.021 | |
| Ccl20 | chemokine (C-C motif) ligand 20 | 0.021 | |
| PVR | poliovirus receptor | 0.021 | |
| Egr2 | early growth response 2 | 0.020 | |
| Ripk2 | receptor-interacting serine-threonine kinase 2 | 0.020 | |
| Tnfrsf26 | tumor necrosis factor receptor superfamily, member 26 | 0.019 | |
| Cst7 | cystatin F (leukocystatin) | 0.019 | |
| Tlr7 | toll-like receptor 7 | 0.018 | |
| Hpgds | hematopoietic prostaglandin D synthase | 0.017 | |
| Spp1 | secreted phosphoprotein 1 | 0.017 | |
| Fosl1 | fos-like antigen 1 | 0.016 | |
| Plscr1 | phospholipid scramblase 1 | 0.016 | |
| Mcpt8 | mast cell protease 8 | 0.016 | |
| Rassf9 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 | 0.016 | |
| Cebpd | CCAAT/enhancer binding protein (C/EBP), delta | 0.016 | |
| Cldn4 | claudin 4 | 0.016 | |
| Nox4 | NADPH oxidase 4 | 0.016 | |
| Kdr | kinase insert domain receptor | 0.015 | |
| Cd8a | CD8a molecule | 0.015 | |
| Tnfrsf12a | tumor necrosis factor receptor superfamily, member 12a | 0.015 | |
| Junb | jun B proto-oncogene | 0.015 | |
| Tcrb | T-cell receptor beta chain | 0.014 | |
| Il7r | interleukin 7 receptor | 0.014 | |
| RT1-Bb | RT1 class II, locus Bb | 0.014 | |
| Lilrb4 | leukocyte immunoglobulin-like receptor, subfamily B, member 4 | 0.013 | |
| Bst1 | bone marrow stromal cell antigen 1 | 0.013 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.013 | |
| Mcm2 | minichromosome maintenance complex component 2 | 0.013 | |
| Postn | periostin, osteoblast specific factor | 0.013 | |
| Plod2 | procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.012 | |
| Fst | follistatin | 0.012 | |
| Arl5c | ADP-ribosylation factor-like 5C | 0.012 | |
| Fas | Fas (TNF receptor superfamily, member 6) | 0.011 | |
| Tchh | trichohyalin | 0.011 |