The network for 'cellular protein localization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular protein localization

Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.

Rattus norvegicus
Name Description Probability Func Analog Organism
Pfn1 profilin 1 0.791
Mapk1 mitogen activated protein kinase 1 0.771
Gria2 glutamate receptor, ionotropic, AMPA 2 0.761
Myadm myeloid-associated differentiation marker 0.643
Zranb2 zinc finger, RAN-binding domain containing 2 0.498
Dlg1 discs, large homolog 1 (Drosophila) 0.492
Rhoa ras homolog gene family, member A 0.467
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.463
Cav1 caveolin 1, caveolae protein 0.454
Hsph1 heat shock 105/110 protein 1 0.449
Dnm1l dynamin 1-like 0.407
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.394
S100a10 S100 calcium binding protein A10 0.349
Ppp2ca protein phosphatase 2, catalytic subunit, alpha isoform 0.347
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.334
Kif1b kinesin family member 1B 0.334
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.326
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.306
Anxa2 annexin A2 0.304
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.301
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.292
Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.290
Smad7 SMAD family member 7 0.272
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform 0.272
Anxa5 annexin A5 0.269
Sdcbp syndecan binding protein 0.269
Nlgn3 neuroligin 3 0.268
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.268
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.267
Grm7 glutamate receptor, metabotropic 7 0.265
Dlgap3 discs, large (Drosophila) homolog-associated protein 3 0.264
LOC100362824 caveolin 2-like 0.256
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.253
Rraga Ras-related GTP binding A 0.252
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform 0.243
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.233
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.231
Gabarapl2 GABA(A) receptor-associated protein like 2 0.228
Dlg4 discs, large homolog 4 (Drosophila) 0.226
Apba1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.226
Nckap1 NCK-associated protein 1 0.224
Lmna lamin A 0.223
Eif4a2 eukaryotic translation initiation factor 4A, isoform 2 0.221
Vim vimentin 0.218
Otub1 OTU domain, ubiquitin aldehyde binding 1 0.217
Pou2f2 POU class 2 homeobox 2 0.215
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.207
Pkia protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.207
Rap1b RAP1B, member of RAS oncogene family 0.204
Rab7a RAB7A, member RAS oncogene family 0.203
Hspb1 heat shock protein 1 0.201
Sumo1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.197
Gria4 glutamate receptor, ionotrophic, AMPA 4 0.192
Taf6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor 0.182
Vegfa vascular endothelial growth factor A 0.179
Hsp90b1 heat shock protein 90, beta, member 1 0.175
Tcof1 Treacher Collins-Franceschetti syndrome 1 homolog (human) 0.175
Mylk2 myosin light chain kinase 2 0.172
RGD1562618 similar to RIKEN cDNA 6030419C18 gene 0.170
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.168
Taok1 TAO kinase 1 0.167
Kalrn kalirin, RhoGEF kinase 0.167
Ap2s1 adaptor-related protein complex 2, sigma 1 subunit 0.166
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.165
Tle4 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) 0.162
Pdcl phosducin-like 0.158
Accn1 amiloride-sensitive cation channel 1, neuronal 0.157
Ptafr platelet-activating factor receptor 0.154
Pdc phosducin 0.153
Tpm3 tropomyosin 3, gamma 0.153
Kcna3 potassium voltage-gated channel, shaker-related subfamily, member 3 0.153
Jak2 Janus kinase 2 0.151
Rnf4 ring finger protein 4 0.149
Tmed2 transmembrane emp24 domain trafficking protein 2 0.146
Homer1 homer homolog 1 (Drosophila) 0.145
Cltc clathrin, heavy chain (Hc) 0.144
Nos2 nitric oxide synthase 2, inducible 0.144
Kctd13 potassium channel tetramerisation domain containing 13 0.143
Gja1 gap junction protein, alpha 1 0.143
Htr4 5-hydroxytryptamine (serotonin) receptor 4 0.142
Cd9 CD9 molecule 0.141
Arpc2 actin related protein 2/3 complex, subunit 2 0.141
Stxbp1 syntaxin binding protein 1 0.137
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.136
Rc3h2 ring finger and CCCH-type zinc finger domains 2 0.136
Grm5 glutamate receptor, metabotropic 5 0.134
Anxa4 annexin A4 0.133
Ppp2r2c protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform 0.133
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.132
Clic1 chloride intracellular channel 1 0.130
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.130
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.129
Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform 0.128
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.127
Gria3 glutamate receptor, ionotrophic, AMPA 3 0.126
Rab6a RAB6A, member RAS oncogene family 0.124
Accn2 amiloride-sensitive cation channel 2, neuronal 0.123
Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.122
Csrnp2 cysteine-serine-rich nuclear protein 2 0.122
Notch3 Notch homolog 3 (Drosophila) 0.122
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
mpk-1 Protein MPK-1 0.748
goa-1 Protein GOA-1 0.544
atn-1 Protein ATN-1 0.522
lin-36 Protein LIN-36 0.314
osm-5 Protein OSM-5 0.291
ajm-1 Protein AJM-1 0.289
D1081.8 Protein D1081.8 0.285
daf-3 Protein DAF-3 0.265
sem-5 Protein SEM-5 0.222
egl-8 Protein EGL-8 0.209
imb-2 Protein IMB-2 0.208
npp-7 Protein NPP-7 0.203
che-13 Protein CHE-13 0.201
egl-18 Protein EGL-18 0.188
zyg-8 Protein ZYG-8 0.187
pha-4 Protein PHA-4 0.186
zyg-9 Protein ZYG-9 0.183
egl-44 Protein EGL-44 0.182
syx-5 Protein SYX-5 0.181
let-60 Protein LET-60 0.173
dcr-1 Protein DCR-1 0.165
akt-1 Protein AKT-1 0.159
stam-1 Protein STAM-1 0.159
knl-1 Protein KNL-1 0.158
nphp-4 Protein NPHP-4 0.154
csnk-1 Protein CSNK-1 0.149
F09E5.7 Protein F09E5.7 0.144
hcp-4 Protein HCP-4 0.137
vps-53 Protein VPS-53 0.133
unc-9 Protein UNC-9 0.132
chaf-1 Protein CHAF-1 0.131
flh-1 Protein FLH-1 0.126
hsp-1 Protein HSP-1 0.126
pry-1 Protein PRY-1 0.124
fem-1 Protein FEM-1 0.122
sop-3 Protein SOP-3 0.122
pdl-1 Protein PDL-1 0.122
mat-3 Protein MAT-3 0.118
clic-1 Protein CLIC-1 0.117
mig-15 Protein MIG-15 0.115
sas-5 Protein SAS-5 0.113
cmd-1 Protein CMD-1 0.113
soc-2 Protein SOC-2 0.112
tram-1 Protein TRAM-1 0.112
rho-1 Protein RHO-1 0.111
mbk-2 Protein MBK-2 0.108
tbb-2 Protein TBB-2 0.108
inx-13 Protein INX-13 0.106
R90.1 Protein R90.1 0.106
unc-52 Protein UNC-52 0.104
ada-2 Protein ADA-2 0.100
ttm-4 Protein TTM-4 0.099
che-2 Protein CHE-2 0.098
C13F10.4 Protein C13F10.4 0.098
nphp-1 Protein NPHP-1 0.098
arl-8 Protein ARL-8 0.098
CELE_Y60A3A.9 Protein Y60A3A.9 0.098
pmk-1 Protein PMK-1 0.098
unc-73 Protein UNC-73 0.095
unc-10 Protein UNC-10 0.094
npp-19 Protein NPP-19 0.093
unc-112 Protein UNC-112 0.092
lap-2 Protein LAP-2 0.091
R11A8.7 Protein R11A8.7 0.090
sma-6 Protein SMA-6 0.090
ostd-1 Protein OSTD-1 0.089
sax-7 Protein SAX-7 0.087
CELE_T03F6.3 Protein T03F6.3 0.087
yif-1 Protein YIF-1 0.086
C30C11.4 Protein C30C11.4 0.085
sad-1 Protein SAD-1 0.085
pdfr-1 Protein PDFR-1 0.084
ncam-1 Protein NCAM-1 0.083
CELE_C01G6.5 Protein C01G6.5 0.082
T14B1.1 Protein T14B1.1 0.081
egal-1 Protein EGAL-1 0.080
tat-4 Protein TAT-4 0.080
F14B8.6 Protein F14B8.6 0.080
sax-3 Protein SAX-3 0.080
pdi-3 Protein PDI-3 0.080
dpy-30 Protein DPY-30 0.079
bbs-8 Protein BBS-8 0.079
osm-12 Protein OSM-12 0.078
sas-4 Protein SAS-4 0.077
ntl-4 Protein NTL-4 0.077
dcp-66 Protein DCP-66 0.076
vha-9 Protein VHA-9 0.076
pmp-3 Protein PMP-3 0.075
plk-1 Protein PLK-1 0.074
K12H4.4 Protein K12H4.4 0.073
kin-4 Protein KIN-4 0.073
ldb-1 Protein LDB-1 0.073
snap-1 Protein SNAP-1 0.071
mel-28 Protein MEL-28 0.071
jbts-14 Protein JBTS-14 0.071
gdi-1 Protein GDI-1 0.071
lmn-1 Protein LMN-1 0.071
vav-1 Protein VAV-1 0.070
tam-1 Protein TAM-1 0.069
T24G10.2 Protein T24G10.2 0.069
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.201
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.166
per2 period homolog 2 (Drosophila) 0.134
pkd2 polycystic kidney disease 2 0.097
znf703 zinc finger protein 703 0.093
sox9a SRY-box containing gene 9a 0.091
pitx3 paired-like homeodomain transcription factor 3 0.089
aplnra apelin receptor a 0.089
traf4a tnf receptor-associated factor 4a 0.085
bmp4 bone morphogenetic protein 4 0.083
alcamb activated leukocyte cell adhesion molecule b 0.078
cry1a cryptochrome 1a 0.078
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.076
sept2 septin 2 0.066
arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.065
hspd1 heat shock 60kD protein 1 (chaperonin) 0.064
runx2a runt-related transcription factor 2a 0.063
plk1 polo-like kinase 1 (Drosophila) 0.062
ptpra protein tyrosine phosphatase, receptor type, A 0.060
smad1 MAD homolog 1 (Drosophila) 0.056
unc45b unc-45 homolog B (C. elegans) 0.056
sumo2 SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) 0.055
arpc5a actin related protein 2/3 complex, subunit 5A 0.055
nrp2b neuropilin 2b 0.053
egr1 early growth response 1 0.053
nkx2.2a NK2 transcription factor related 2a 0.052
sox9b SRY-box containing gene 9b 0.051
cdh1 cadherin 1, epithelial 0.051
cltca clathrin, heavy polypeptide a (Hc) 0.049
igf1rb insulin-like growth factor 1b receptor 0.048
nadl1.2 neural adhesion molecule L1.2 0.047
bmp2b bone morphogenetic protein 2b 0.047
tomm40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.047
lama4 laminin, alpha 4 0.047
igf1ra insulin-like growth factor 1a receptor 0.045
dlg2 discs, large (Drosophila) homolog 2 0.045
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.045
gnrh2 gonadotropin-releasing hormone 2 0.044
acvr1b activin A receptor, type IB 0.044
eng1b engrailed 1b 0.044
myod1 myogenic differentiation 1 0.044
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.044
dmd dystrophin 0.043
ef1a elongation factor 1-alpha 0.043
ifnphi1 interferon phi 1 0.041
zgc:195154 zgc:195154 0.041
per3 period homolog 3 (Drosophila) 0.040
krt8 keratin 8 0.040
cyfip2 cytoplasmic FMR1 interacting protein 2 0.040
tpt1 tumor protein, translationally-controlled 1 0.040
brd2a bromodomain-containing 2a 0.040
wnt11r wingless-type MMTV integration site family, member 11, related 0.039
rap1b RAS related protein 1b 0.039
jun jun proto-oncogene 0.039
hapln1a hyaluronan and proteoglycan link protein 1a 0.038
lamb2 laminin, beta 2 (laminin S) 0.038
gfra1b gdnf family receptor alpha 1b 0.037
lef1 lymphocyte enhancer binding factor 1 0.036
tomm34 translocase of outer mitochondrial membrane 34 0.035
oprm1 opioid receptor, mu 1 0.035
boc brother of CDO 0.035
ccna2 cyclin A2 0.035
smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.035
dusp6 dual specificity phosphatase 6 0.034
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.034
kif23 kinesin family member 23 0.033
fmr1 fragile X mental retardation 1 0.033
jag1b jagged 1b 0.033
lmna lamin A 0.032
rangap1 Ran GTPase activating protein 1 0.032
atp6v1h ATPase, H+ transporting, lysosomal, V1 subunit H 0.032
snai1a snail homolog 1a (Drosophila) 0.032
plagl2 pleiomorphic adenoma gene-like 2 0.032
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.031
itgb1b.2 integrin, beta 1b.2 0.031
grb10a growth factor receptor-bound protein 10a 0.031
ephb4a eph receptor B4a 0.030
cdc42 cell division cycle 42 0.030
dkk1b dickkopf 1b 0.030
stac3 SH3 and cysteine rich domain 3 0.030
zmynd11 zinc finger, MYND domain containing 11 0.030
atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 0.030
dlg1 discs, large (Drosophila) homolog 1 0.030
cntn1b contactin 1b 0.029
si:ch211-212m21.5 si:ch211-212m21.5 0.029
mapk6 mitogen-activated protein kinase 6 0.029
tbx1 T-box 1 0.029
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.029
ssrp1a structure specific recognition protein 1a 0.028
plcg1 phospholipase C, gamma 1 0.028
sec61al1 Sec61 alpha like 1 0.028
rab1a RAB1A, member RAS oncogene family 0.028
copa coatomer protein complex, subunit alpha 0.028
mtp microsomal triglyceride transfer protein 0.028
nup107 nucleoporin 107 0.028
ednra endothelin receptor type A 0.028
smad9 MAD homolog 9 (Drosophila) 0.027
cxcr4a chemokine (C-X-C motif) receptor 4a 0.027
plcb3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.027
lsr lipolysis stimulated lipoprotein receptor 0.027
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Rab11 Rab-protein 11 0.955
Ras85D Ras oncogene at 85D 0.914
chic chickadee 0.909
Mad Mothers against dpp 0.898
Rab5 Rab-protein 5 0.849
Moe Moesin 0.838
eIF-4E Eukaryotic initiation factor 4E 0.810
zip zipper 0.803
Gug Grunge 0.790
Rheb CG1081 gene product from transcript CG1081-RA 0.790
aPKC atypical protein kinase C 0.768
raps rapsynoid 0.756
l(2)gl lethal (2) giant larvae 0.743
pav pavarotti 0.739
Act5C Actin 5C 0.725
Uba1 Ubiquitin activating enzyme 1 0.719
eya eyes absent 0.712
Rac1 CG2248 gene product from transcript CG2248-RA 0.673
Sec61alpha CG9539 gene product from transcript CG9539-RA 0.666
Syx1A Syntaxin 1A 0.642
ttv tout-velu 0.630
cpa capping protein alpha 0.601
yki yorkie 0.542
cpb capping protein beta 0.542
baz bazooka 0.531
dally division abnormally delayed 0.529
Snap Soluble NSF attachment protein 0.527
Pp2A-29B Protein phosphatase 2A at 29B 0.525
CG11164 CG11164 gene product from transcript CG11164-RA 0.508
ci cubitus interruptus 0.499
aop anterior open 0.495
smt3 CG4494 gene product from transcript CG4494-RA 0.486
Akt1 CG4006 gene product from transcript CG4006-RA 0.476
aux auxillin 0.475
POSH Plenty of SH3s 0.470
gig gigas 0.441
didum dilute class unconventional myosin 0.440
Lis-1 Lissencephaly-1 0.432
pnt pointed 0.432
tws twins 0.427
CaMKII Calcium/calmodulin-dependent protein kinase II 0.419
phl pole hole 0.411
Sir2 CG5216 gene product from transcript CG5216-RA 0.406
Taf1 TBP-associated factor 1 0.403
puc puckered 0.399
key kenny 0.397
rhea CG6831 gene product from transcript CG6831-RA 0.396
rst roughest 0.391
Src64B Src oncogene at 64B 0.383
Tsc1 CG6147 gene product from transcript CG6147-RA 0.374
p120ctn Adherens junction protein p120 0.373
hyd hyperplastic discs 0.353
bs blistered 0.353
Dsor1 Downstream of raf1 0.353
shot short stop 0.353
Syx7 Syntaxin 7 0.342
egl egalitarian 0.334
Nrx-IV Neurexin IV 0.327
tum tumbleweed 0.324
neuroligin CG13772 gene product from transcript CG13772-RA 0.323
Pp2B-14D Protein phosphatase 2B at 14D 0.316
alpha-Adaptin CG4260 gene product from transcript CG4260-RA 0.311
Pp1-87B Protein phosphatase 1 at 87B 0.306
ft fat 0.302
N Notch 0.300
Patj CG12021 gene product from transcript CG12021-RC 0.299
Tip60 CG6121 gene product from transcript CG6121-RA 0.296
ctp cut up 0.292
asp abnormal spindle 0.289
thr three rows 0.284
RhoGEF2 CG9635 gene product from transcript CG9635-RF 0.284
Fs(2)Ket Female sterile (2) Ketel 0.280
mbt mushroom bodies tiny 0.279
pex2 peroxin 2 0.278
eff effete 0.276
Dlic Dynein light intermediate chain 0.272
rok Rho-kinase 0.269
frc fringe connection 0.266
trc tricornered 0.264
Sas-4 CG10061 gene product from transcript CG10061-RA 0.263
CG9053 CG9053 gene product from transcript CG9053-RA 0.261
per period 0.259
Pp4-19C Protein phosphatase 19C 0.257
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.255
egr eiger 0.253
lqf liquid facets 0.249
Bap60 Brahma associated protein 60kD 0.247
flw flapwing 0.246
Cdc42 CG12530 gene product from transcript CG12530-RA 0.244
crb crumbs 0.241
Arp14D Actin-related protein 14D 0.240
so sine oculis 0.239
Aly CG1101 gene product from transcript CG1101-RA 0.237
pex10 peroxin 10 0.237
car carnation 0.236
dsh dishevelled 0.234
ben bendless 0.232
Dcr-2 Dicer-2 0.226
spd-2 spindle defective 2 0.225
wdb widerborst 0.225
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism