The network for 'hormone catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

hormone catabolic process

The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.

Rattus norvegicus
Name Description Probability Func Analog Organism
LOC100361547 Cytochrome P450, family 2, subfamily c, polypeptide 7-like 0.680
Gsta5 glutathione S-transferase Yc2 subunit 0.669
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 0.560
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.427
Sult2al1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1 0.401
Mgst2 microsomal glutathione S-transferase 2 0.334
Ugt2b37 UDP-glucuronosyltransferase 2 family, member 37 0.249
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.219
Akap14 A kinase (PRKA) anchor protein 14 0.190
Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 0.150
Anpep alanyl (membrane) aminopeptidase 0.149
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.131
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.131
LOC494499 LOC494499 protein 0.114
Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5 0.110
Ugt2b36 UDP glucuronosyltransferase 2 family, polypeptide B36 0.092
RGD1309414 similar to KIAA0913 protein 0.087
Nat2 N-acetyltransferase 2 0.077
Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C 0.077
Akr1c14 aldo-keto reductase family 1, member C14 0.074
Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 0.068
Sult2a2 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2 0.060
Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 0.058
Por P450 (cytochrome) oxidoreductase 0.056
Ltbr lymphotoxin beta receptor (TNFR superfamily, member 3) 0.051
Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 0.047
RGD1305347 similar to RIKEN cDNA 2610528J11 0.044
Olr1530 olfactory receptor 1530 0.043
RGD1559532 RGD1559532 0.039
Snrk SNF related kinase 0.037
Phex phosphate regulating endopeptidase homolog, X-linked 0.036
Fcgrt Fc fragment of IgG, receptor, transporter, alpha 0.036
Otc ornithine carbamoyltransferase 0.035
Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 0.035
Nmu neuromedin U 0.034
Ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 0.034
Idh1 isocitrate dehydrogenase 1 (NADP+), soluble 0.034
Apob apolipoprotein B 0.033
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.032
Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 0.029
Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.028
Olr1366 olfactory receptor 1366 0.027
Rag1 recombination activating gene 1 0.026
Olr1191 olfactory receptor 1191 0.026
Met met proto-oncogene 0.026
Ddc dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.023
Irf2 interferon regulatory factor 2 0.021
Chp calcium binding protein p22 0.021
Gns glucosamine (N-acetyl)-6-sulfatase 0.021
Akr1d1 aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) 0.020
Haao 3-hydroxyanthranilate 3,4-dioxygenase 0.020
Fabp2 fatty acid binding protein 2, intestinal 0.020
Ephx1 epoxide hydrolase 1, microsomal 0.020
Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.019
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.019
Slco1a1 solute carrier organic anion transporter family, member 1a1 0.019
Flt1 FMS-related tyrosine kinase 1 0.019
Keg1 kidney expressed gene 1 0.019
Vcsa2 variable coding sequence A2 0.018
Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 0.017
Pctp phosphatidylcholine transfer protein 0.017
Ddx4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 0.017
Clca4 chloride channel accessory 4 0.016
LOC690507 similar to Vomeromodulin 0.016
Ces1e carboxylesterase 1E 0.016
Slc22a18 solute carrier family 22, member 18 0.016
Pigr polymeric immunoglobulin receptor 0.016
LOC100365195 rCG64293-like 0.016
Olr1082 olfactory receptor 1082 0.016
Olr1347 olfactory receptor 1347 0.016
Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 0.015
Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 0.015
Ugt1a8 UDP glycosyltransferase 1 family, polypeptide A8 0.015
Col4a3 collagen, type IV, alpha 3 0.015
Olr1280 olfactory receptor 1280 0.014
Cps1 carbamoyl-phosphate synthetase 1 0.014
Fgf1 fibroblast growth factor 1 0.014
Olr1226 olfactory receptor 1226 0.014
LOC100365112 carboxylesterase-like 0.013
Tbl1xr1 transducin (beta)-like 1 X-linked receptor 1 0.013
LOC293989 cytochrome P450-like 0.013
Egfr epidermal growth factor receptor 0.013
Fn1 fibronectin 1 0.013
Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 0.013
L3mbtl3 l(3)mbt-like 3 (Drosophila) 0.013
Crygf crystallin, gamma F 0.013
Acsm2 acyl-CoA synthetase medium-chain family member 2 0.012
Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 0.012
Sult1c2 sulfotransferase family, cytosolic, 1C, member 2 0.012
Tns1 tensin 1 0.012
Olr1697 olfactory receptor 1697 0.012
Vom2r50 vomeronasal 2 receptor, 50 0.012
Pttg1ip pituitary tumor-transforming 1 interacting protein 0.012
Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.012
Plxnb2 plexin B2 0.012
Adss adenylosuccinate synthase 0.012
Il4ra interleukin 4 receptor, alpha 0.011
Nqo1 NAD(P)H dehydrogenase, quinone 1 0.011
Galnt1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) 0.011
Il2ra interleukin 2 receptor, alpha 0.011
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
CG13310 CG13310 gene product from transcript CG13310-RA 0.876
Ugt35a UDP-glycosyltransferase 35a 0.424
proPO-A1 prophenol oxidase A1 0.298
CG9360 CG9360 gene product from transcript CG9360-RA 0.238
CG2736 CG2736 gene product from transcript CG2736-RA 0.215
Acph-1 Acid phosphatase 1 0.208
NtR CG6698 gene product from transcript CG6698-RA 0.204
Cyp6a21 CG10247 gene product from transcript CG10247-RA 0.202
Cyp4ac1 CG14032 gene product from transcript CG14032-RA 0.166
CG11149 CG11149 gene product from transcript CG11149-RD 0.166
Jheh3 Juvenile hormone epoxide hydrolase 3 0.162
CG33307 CG33307 gene product from transcript CG33307-RA 0.161
CG11147 CG11147 gene product from transcript CG11147-RA 0.157
Men Malic enzyme 0.155
Sr-CI Scavenger receptor class C, type I 0.154
CG3967 CG3967 gene product from transcript CG3967-RC 0.153
CG5973 CG5973 gene product from transcript CG5973-RA 0.150
glob1 globin 1 0.150
CG6426 CG6426 gene product from transcript CG6426-RA 0.143
CG1124 CG1124 gene product from transcript CG1124-RA 0.142
CG15096 CG15096 gene product from transcript CG15096-RA 0.139
CG7272 CG7272 gene product from transcript CG7272-RA 0.137
CG3702 CG3702 gene product from transcript CG3702-RA 0.136
CG8773 CG8773 gene product from transcript CG8773-RB 0.127
Est-6 Esterase 6 0.126
Tg Transglutaminase 0.124
Cyp4d21 CG6730 gene product from transcript CG6730-RA 0.121
Syx4 Syntaxin 4 0.112
Aldh-III Aldehyde dehydrogenase type III 0.109
CG42807 CG42807 gene product from transcript CG42807-RA 0.108
CG13631 CG13631 gene product from transcript CG13631-RA 0.101
CG13360 CG13360 gene product from transcript CG13360-RA 0.100
CG17928 CG17928 gene product from transcript CG17928-RA 0.099
Ugt86Dc CG4739 gene product from transcript CG4739-RA 0.098
CG12746 CG12746 gene product from transcript CG12746-RD 0.096
CG14457 CG14457 gene product from transcript CG14457-RA 0.095
Ugt86Dh CG4772 gene product from transcript CG4772-RA 0.091
CG8193 CG8193 gene product from transcript CG8193-RA 0.090
Myo61F Myosin 61F 0.090
CG6834 CG6834 gene product from transcript CG6834-RA 0.088
CG4721 CG4721 gene product from transcript CG4721-RA 0.088
Hexo2 Hexosaminidase 2 0.087
CG4950 CG4950 gene product from transcript CG4950-RB 0.085
Cyp12e1 CG14680 gene product from transcript CG14680-RC 0.085
Cyp4e2 Cytochrome P450-4e2 0.085
Fkbp13 CG9847 gene product from transcript CG9847-RC 0.084
vir-1 virus-induced RNA 1 0.084
CG10562 CG10562 gene product from transcript CG10562-RA 0.082
Or22a Odorant receptor 22a 0.081
sxe2 sex-specific enzyme 2 0.081
Est-P Esterase P 0.080
CG14856 CG14856 gene product from transcript CG14856-RA 0.080
Cyp6d4 CG12800 gene product from transcript CG12800-RA 0.079
CG10433 CG10433 gene product from transcript CG10433-RA 0.077
CG5361 CG5361 gene product from transcript CG5361-RA 0.077
CG15828 CG15828 gene product from transcript CG15828-RC 0.075
Ugt36Ba CG13270 gene product from transcript CG13270-RA 0.074
CG13284 CG13284 gene product from transcript CG13284-RA 0.073
CG3376 CG3376 gene product from transcript CG3376-RB 0.071
Trf4-1 CG11265 gene product from transcript CG11265-RE 0.069
CG5390 CG5390 gene product from transcript CG5390-RA 0.069
Cyp4e1 Cytochrome P450-4e1 0.068
CG1092 CG1092 gene product from transcript CG1092-RA 0.067
CG6126 CG6126 gene product from transcript CG6126-RA 0.067
CG13875 CG13875 gene product from transcript CG13875-RA 0.067
CG9512 CG9512 gene product from transcript CG9512-RA 0.067
CG3246 CG3246 gene product from transcript CG3246-RA 0.066
CG10184 CG10184 gene product from transcript CG10184-RA 0.066
Ugt86Dj CG15902 gene product from transcript CG15902-RA 0.066
CG4239 CG4239 gene product from transcript CG4239-RA 0.066
homer CG11324 gene product from transcript CG11324-RC 0.063
CG1941 CG1941 gene product from transcript CG1941-RA 0.063
Cyp4d14 CG3540 gene product from transcript CG3540-RA 0.062
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.062
CG9497 CG9497 gene product from transcript CG9497-RA 0.060
CG18507 CG18507 gene product from transcript CG18507-RB 0.060
MP1 Melanization Protease 1 0.060
CG16732 CG16732 gene product from transcript CG16732-RB 0.059
CG4822 CG4822 gene product from transcript CG4822-RB 0.059
CG6910 CG6910 gene product from transcript CG6910-RB 0.058
CG10553 CG10553 gene product from transcript CG10553-RA 0.058
CG18327 CG18327 gene product from transcript CG18327-RA 0.057
CG13002 CG13002 gene product from transcript CG13002-RA 0.057
CG17026 CG17026 gene product from transcript CG17026-RA 0.057
CG13658 CG13658 gene product from transcript CG13658-RB 0.057
CG18249 CG18249 gene product from transcript CG18249-RB 0.057
to takeout 0.055
arg arginase 0.055
CG10051 CG10051 gene product from transcript CG10051-RA 0.053
Rh50 CG7499 gene product from transcript CG7499-RA 0.053
PH4alphaEFB prolyl-4-hydroxylase-alpha EFB 0.052
alpha-Est1 alpha-Esterase-1 0.052
CG33012 CG33012 gene product from transcript CG33012-RA 0.052
CG18324 CG18324 gene product from transcript CG18324-RB 0.052
CG9642 CG9642 gene product from transcript CG9642-RA 0.051
CG9743 CG9743 gene product from transcript CG9743-RA 0.051
CG31103 CG31103 gene product from transcript CG31103-RB 0.051
Pbprp3 Pheromone-binding protein-related protein 3 0.051
CG33120 CG33120 gene product from transcript CG33120-RA 0.051
CG12703 CG12703 gene product from transcript CG12703-RA 0.051
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Homo sapiens
Name Description Probability Func Analog Organism
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.999
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.998
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) 0.986
CCL3 chemokine (C-C motif) ligand 3 0.806
TUBB8 tubulin, beta 8 0.314
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.219
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 0.095
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 0.081
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.075
SEC23IP SEC23 interacting protein 0.035
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.030
LARP4 La ribonucleoprotein domain family, member 4 0.029
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.025
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 0.023
SH3BGRL SH3 domain binding glutamic acid-rich protein like 0.021
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.020
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.018
MTFR1 mitochondrial fission regulator 1 0.018
CCDC6 coiled-coil domain containing 6 0.018
MRVI1 murine retrovirus integration site 1 homolog 0.018
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 0.017
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.017
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 0.017
ZW10 ZW10, kinetochore associated, homolog (Drosophila) 0.016
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.016
GUF1 GUF1 GTPase homolog (S. cerevisiae) 0.015
CD302 CD302 molecule 0.015
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.015
AKR1C4 aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4) 0.015
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.015
BDKRB2 bradykinin receptor B2 0.015
RNASE4 ribonuclease, RNase A family, 4 0.014
UTRN utrophin 0.014
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.014
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 0.014
MAN1A1 mannosidase, alpha, class 1A, member 1 0.013
NQO1 NAD(P)H dehydrogenase, quinone 1 0.013
AADAC arylacetamide deacetylase (esterase) 0.013
MAPK14 mitogen-activated protein kinase 14 0.012
HRG histidine-rich glycoprotein 0.012
FAM83F family with sequence similarity 83, member F 0.012
PIR pirin (iron-binding nuclear protein) 0.012
RAD50 RAD50 homolog (S. cerevisiae) 0.012
PRLR prolactin receptor 0.012
LXN latexin 0.012
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.012
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.011
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa 0.011
LRRC31 leucine rich repeat containing 31 0.011
RAP2B RAP2B, member of RAS oncogene family 0.011
ECD ecdysoneless homolog (Drosophila) 0.011
SI sucrase-isomaltase (alpha-glucosidase) 0.011
SLC26A3 solute carrier family 26, member 3 0.011
CES1 carboxylesterase 1 0.011
LOC729020 rcRPE 0.011
F13B coagulation factor XIII, B polypeptide 0.011
NFRKB nuclear factor related to kappaB binding protein 0.011
MBTPS2 membrane-bound transcription factor peptidase, site 2 0.011
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.011
TM4SF4 transmembrane 4 L six family member 4 0.011
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.010
TFF3 trefoil factor 3 (intestinal) 0.010
FRK fyn-related kinase 0.010
KBTBD3 kelch repeat and BTB (POZ) domain containing 3 0.010
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.010
BCMO1 beta-carotene 15,15'-monooxygenase 1 0.010
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 0.010
TSPAN8 tetraspanin 8 0.010
HNF4G hepatocyte nuclear factor 4, gamma 0.010
METTL7A methyltransferase like 7A 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Ren1 renin 1 structural 0.234
Lepr leptin receptor 0.076
Agtr1a angiotensin II receptor, type 1a 0.050
Glis2 GLIS family zinc finger 2 0.036
Thra thyroid hormone receptor alpha 0.030
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.028
Slc12a1 solute carrier family 12, member 1 0.018
Aqp2 aquaporin 2 0.017
Vav3 vav 3 oncogene 0.015
Umod uromodulin 0.012
Vav2 vav 2 oncogene 0.011
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.011
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism