The network for 'regulation of transcription by chromatin organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of transcription by chromatin organization

Any cellular process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin that modulates the rate, frequency or extent of DNA-dependent transcription.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
HHT1 Hht1p 0.776
RTF1 Rtf1p 0.330
ITC1 Itc1p 0.256
SGF73 Sgf73p 0.184
SPT16 Spt16p 0.140
SAS4 Sas4p 0.125
MIG2 Mig2p 0.125
ISW1 Isw1p 0.107
TRA1 Tra1p 0.106
HHO1 Hho1p 0.102
ADA2 Ada2p 0.099
MIG1 Mig1p 0.094
NRG1 Nrg1p 0.093
DLS1 Dls1p 0.093
BDF1 Bdf1p 0.090
POB3 Pob3p 0.089
HOS4 Hos4p 0.087
LEO1 Leo1p 0.084
RCO1 Rco1p 0.078
HHT2 Hht2p 0.073
BDF2 Bdf2p 0.072
SPT6 Spt6p 0.072
SPT5 Spt5p 0.071
NUP170 Nup170p 0.069
CHD1 Chd1p 0.061
SWI1 Swi1p 0.060
YKR075C hypothetical protein 0.059
CKA1 Cka1p 0.058
SIN3 Sin3p 0.057
DPB2 Dpb2p 0.057
SAS5 Sas5p 0.055
YCL021W-A hypothetical protein 0.055
TAF12 Taf12p 0.053
VAC7 Vac7p 0.053
MIG3 Mig3p 0.052
HAL5 Hal5p 0.051
GAT2 Gat2p 0.051
CSR2 Csr2p 0.050
LYS5 Lys5p 0.050
YTA7 Yta7p 0.050
HHF2 Hhf2p 0.049
NTO1 Nto1p 0.046
SPT8 Spt8p 0.046
SET3 Set3p 0.046
HDA3 Hda3p 0.046
HTB2 Htb2p 0.044
NGG1 Ngg1p 0.043
SET2 Set2p 0.043
HAA1 Haa1p 0.040
CTR9 Ctr9p 0.040
MDN1 Mdn1p 0.039
YNG1 Yng1p 0.039
ROX1 Rox1p 0.038
OPI1 Opi1p 0.037
TIF4632 Tif4632p 0.037
MOT1 Mot1p 0.036
RIF1 Rif1p 0.035
SPT20 Spt20p 0.035
SNT1 Snt1p 0.035
HDA2 Hda2p 0.034
IOC4 Ioc4p 0.034
HST1 Hst1p 0.033
TMA22 Tma22p 0.033
SIW14 Siw14p 0.032
UBP14 Ubp14p 0.032
SIR2 Sir2p 0.032
HAL1 Hal1p 0.032
KIC1 Kic1p 0.032
HIR2 Hir2p 0.031
GIP2 Gip2p 0.031
BUD4 Bud4p 0.031
YKL187C hypothetical protein 0.031
MBR1 Mbr1p 0.031
HXT3 Hxt3p 0.030
CUP9 Cup9p 0.030
PSH1 Psh1p 0.030
HOS3 Hos3p 0.030
RSC30 Rsc30p 0.029
CPR1 Cpr1p 0.029
NUP157 Nup157p 0.029
KEM1 Kem1p 0.028
SWR1 Swr1p 0.028
ZEO1 Zeo1p 0.028
ARP4 Arp4p 0.027
SIR3 Sir3p 0.027
MLC1 Mlc1p 0.027
RLM1 Rlm1p 0.027
POG1 Pog1p 0.026
CYC8 Cyc8p 0.026
ATG29 Atg29p 0.026
RIM8 Rim8p 0.026
IRC23 Irc23p 0.026
YPL014W hypothetical protein 0.026
YIL151C hypothetical protein 0.025
GIS4 Gis4p 0.025
CKB1 Ckb1p 0.025
RAP1 Rap1p 0.025
EPL1 Epl1p 0.025
MMR1 Mmr1p 0.024
TAF6 Taf6p 0.024
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Jarid2 CG3654 gene product from transcript CG3654-RD 0.221
CTCF CG8591 gene product from transcript CG8591-RA 0.175
Su(var)2-10 Suppressor of variegation 2-10 0.120
Mcm2 Minichromosome maintenance 2 0.098
Su(var)2-HP2 CG12864 gene product from transcript CG12864-RB 0.094
Nup98 Nucleoporin 98 0.086
Su(var)3-3 Suppressor of variegation 3-3 0.080
MBD-like CG8208 gene product from transcript CG8208-RA 0.075
SuUR Suppressor of Under-Replication 0.071
Rpd3 CG7471 gene product from transcript CG7471-RA 0.064
pasha partner of drosha 0.055
pr-set7 CG3307 gene product from transcript CG3307-RC 0.049
Grip84 gamma-tubulin ring protein 84 0.043
Hel25E Helicase at 25E 0.040
Acf1 ATP-dependent chromatin assembly factor large subunit 0.040
BEAF-32 Boundary element-associated factor of 32kD 0.039
Dek CG5935 gene product from transcript CG5935-RA 0.036
hkl hook-like 0.036
Top2 Topoisomerase 2 0.034
E(var)3-9 Enhancer of variegation 3-9 0.034
Suv4-20 CG13363 gene product from transcript CG13363-RA 0.033
Su(var)205 Suppressor of variegation 205 0.033
otu ovarian tumor 0.032
Su(var)3-7 Suppressor of variegation 3-7 0.032
XNP CG4548 gene product from transcript CG4548-RA 0.032
Sir2 CG5216 gene product from transcript CG5216-RA 0.032
Mi-2 CG8103 gene product from transcript CG8103-RA 0.030
spn-E spindle E 0.028
plu plutonium 0.027
Fs(2)Ket Female sterile (2) Ketel 0.027
mael maelstrom 0.026
piwi CG6122 gene product from transcript CG6122-RA 0.026
fs(2)ltoPP43 female sterile (2) ltoPP43 0.026
SMC1 CG6057 gene product from transcript CG6057-RA 0.025
CG14438 CG14438 gene product from transcript CG14438-RA 0.025
png pan gu 0.023
stwl stonewall 0.023
PPP4R2r Protein phosphatase 4 regulatory subunit 2-related protein 0.021
chm chameau 0.021
His2Av Histone H2A variant 0.021
CG11137 CG11137 gene product from transcript CG11137-RA 0.020
asf1 anti-silencing factor 1 0.020
AGO2 Argonaute 2 0.019
mip120 Myb-interacting protein 120 0.019
Gef26 CG9491 gene product from transcript CG9491-RB 0.019
Cypl Cyclophilin-like 0.019
dup double parked 0.019
MEP-1 CG1244 gene product from transcript CG1244-RG 0.018
WRNexo WRN exonuclease 0.018
trr trithorax-related 0.017
BG4 CG12297 gene product from transcript CG12297-RA 0.017
msl-3 male-specific lethal 3 0.017
mus209 mutagen-sensitive 209 0.017
enc encore 0.017
icln CG4924 gene product from transcript CG4924-RA 0.016
CG31122 CG31122 gene product from transcript CG31122-RA 0.016
Gr28b Gustatory receptor 28b 0.016
HP4 Heterochromatin protein 4 0.016
crm cramped 0.016
ash1 absent, small, or homeotic discs 1 0.016
Nup160 Nucleoporin 160 0.015
Mekk1 CG7717 gene product from transcript CG7717-RB 0.015
jumu jumeau 0.015
SMC2 CG10212 gene product from transcript CG10212-RA 0.015
Snm1 CG10018 gene product from transcript CG10018-RA 0.015
pzg putzig 0.015
gkt glaikit 0.015
CG14183 CG14183 gene product from transcript CG14183-RA 0.015
CG7427 CG7427 gene product from transcript CG7427-RA 0.015
bgcn benign gonial cell neoplasm 0.014
Ulp1 CG12359 gene product from transcript CG12359-RA 0.014
CG7239 CG7239 gene product from transcript CG7239-RA 0.014
ird5 immune response deficient 5 0.014
CG3125 CG3125 gene product from transcript CG3125-RA 0.014
CG13022 CG13022 gene product from transcript CG13022-RB 0.014
PGRP-LC Peptidoglycan recognition protein LC 0.014
Df31 Decondensation factor 31 0.014
row relative of woc 0.014
RfC38 Replication factor C 38kD subunit 0.013
enok enoki mushroom 0.013
Nf-YB Nuclear factor Y-box B 0.013
E(z) Enhancer of zeste 0.013
Pgam5 Phosphoglycerate mutase 5 0.013
Grip163 CG5688 gene product from transcript CG5688-RA 0.013
mof males absent on the first 0.013
Map60 Microtubule-associated protein 60 0.013
rod rough deal 0.013
dhd deadhead 0.013
Kmn1 kinetochore Mis12-Ndc80 network component 1 0.013
ph-d polyhomeotic distal 0.013
CG5098 CG5098 gene product from transcript CG5098-RA 0.012
CG6752 CG6752 gene product from transcript CG6752-RA 0.012
CG7713 CG7713 gene product from transcript CG7713-RA 0.012
egg eggless 0.012
Hsp68 Heat shock protein 68 0.012
atms antimeros 0.012
CG2931 CG2931 gene product from transcript CG2931-RA 0.012
CG6418 CG6418 gene product from transcript CG6418-RB 0.012
pie pineapple eye 0.012
Sce Sex combs extra 0.012
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Homo sapiens
Name Description Probability Func Analog Organism
POLE2 polymerase (DNA directed), epsilon 2 (p59 subunit) 0.872
NBN nibrin 0.715
CREBBP CREB binding protein 0.597
CBX5 chromobox homolog 5 0.543
EP300 E1A binding protein p300 0.494
TRRAP transformation/transcription domain-associated protein 0.456
MCM7 minichromosome maintenance complex component 7 0.429
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.335
CDC73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.299
RB1 retinoblastoma 1 0.240
RAD50 RAD50 homolog (S. cerevisiae) 0.229
POLE3 polymerase (DNA directed), epsilon 3 (p17 subunit) 0.227
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.209
SSRP1 structure specific recognition protein 1 0.201
TGIF1 TGFB-induced factor homeobox 1 0.196
HIST1H3B histone cluster 1, H3b 0.168
LBR lamin B receptor 0.154
WRN Werner syndrome, RecQ helicase-like 0.135
ADNP activity-dependent neuroprotector homeobox 0.119
NRIP1 nuclear receptor interacting protein 1 0.103
NSL1 NSL1, MIND kinetochore complex component, homolog (S. cerevisiae) 0.102
RAD21 RAD21 homolog (S. pombe) 0.102
CBX1 chromobox homolog 1 0.101
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.099
ATXN7 ataxin 7 0.093
PRRC2C proline-rich coiled-coil 2C 0.085
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.084
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.083
MCM2 minichromosome maintenance complex component 2 0.081
CDK2 cyclin-dependent kinase 2 0.080
RANBP2 RAN binding protein 2 0.078
INCENP inner centromere protein antigens 135/155kDa 0.077
BCLAF1 BCL2-associated transcription factor 1 0.075
CREB1 cAMP responsive element binding protein 1 0.070
USP22 ubiquitin specific peptidase 22 0.068
CHRAC1 chromatin accessibility complex 1 0.067
SMC1A structural maintenance of chromosomes 1A 0.065
RBBP4 retinoblastoma binding protein 4 0.063
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.063
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.058
DHX9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 0.055
HIPK2 homeodomain interacting protein kinase 2 0.053
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.052
MCM3 minichromosome maintenance complex component 3 0.050
RBBP8 retinoblastoma binding protein 8 0.050
KAT2B K(lysine) acetyltransferase 2B 0.049
ORC6 origin recognition complex, subunit 6 0.048
PML promyelocytic leukemia 0.047
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 0.047
MBD1 methyl-CpG binding domain protein 1 0.047
DAXX death-domain associated protein 0.046
SUZ12 suppressor of zeste 12 homolog (Drosophila) 0.044
NCOA3 nuclear receptor coactivator 3 0.043
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.040
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.038
MCMBP minichromosome maintenance complex binding protein 0.038
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 0.037
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.035
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.033
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.033
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.032
APC adenomatous polyposis coli 0.032
MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.031
MDC1 mediator of DNA-damage checkpoint 1 0.031
EED embryonic ectoderm development 0.030
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 0.029
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.029
AR androgen receptor 0.028
NUP50 nucleoporin 50kDa 0.028
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.027
MCM4 minichromosome maintenance complex component 4 0.027
TADA2A transcriptional adaptor 2A 0.027
FOXO3 forkhead box O3 0.027
CDK6 cyclin-dependent kinase 6 0.027
HDAC1 histone deacetylase 1 0.026
NCOA1 nuclear receptor coactivator 1 0.026
ADNP2 ADNP homeobox 2 0.025
MORC3 MORC family CW-type zinc finger 3 0.025
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.025
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.025
RSF1 remodeling and spacing factor 1 0.025
MIS12 MIS12, MIND kinetochore complex component, homolog (S. pombe) 0.025
H2AFV H2A histone family, member V 0.025
POLE4 polymerase (DNA-directed), epsilon 4 (p12 subunit) 0.024
CHAF1B chromatin assembly factor 1, subunit B (p60) 0.024
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 0.024
TADA3 transcriptional adaptor 3 0.023
H3F3B H3 histone, family 3B (H3.3B) 0.023
CRY1 cryptochrome 1 (photolyase-like) 0.023
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.023
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.022
MSH6 mutS homolog 6 (E. coli) 0.022
POGZ pogo transposable element with ZNF domain 0.021
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.021
TOP1 topoisomerase (DNA) I 0.021
HMGXB4 HMG box domain containing 4 0.021
ZEB1 zinc finger E-box binding homeobox 1 0.020
NCOA6 nuclear receptor coactivator 6 0.020
ANKRD17 ankyrin repeat domain 17 0.020
H2AFX H2A histone family, member X 0.020
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Mus musculus
Name Description Probability Func Analog Organism
Smc1a structural maintenance of chromosomes 1A 0.984
Trim28 tripartite motif-containing 28 0.798
Mcm2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) 0.754
Kdm2b lysine (K)-specific demethylase 2B 0.694
Trim24 tripartite motif-containing 24 0.631
Srsf1 serine/arginine-rich splicing factor 1 0.566
Timeless timeless homolog (Drosophila) 0.552
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.383
Rnf2 ring finger protein 2 0.355
Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 0.297
Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) 0.289
Mcm7 minichromosome maintenance deficient 7 (S. cerevisiae) 0.283
Cdt1 chromatin licensing and DNA replication factor 1 0.253
Pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.235
Stag1 stromal antigen 1 0.232
Rcc2 regulator of chromosome condensation 2 0.218
Dnmt1 DNA methyltransferase (cytosine-5) 1 0.215
Lig1 ligase I, DNA, ATP-dependent 0.213
Smc3 structural maintenace of chromosomes 3 0.170
Casp8ap2 caspase 8 associated protein 2 0.152
Mcm6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) 0.150
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.134
Dkc1 dyskeratosis congenita 1, dyskerin homolog (human) 0.132
Cbx5 chromobox homolog 5 (Drosophila HP1a) 0.120
Baz1a bromodomain adjacent to zinc finger domain 1A 0.108
Mecp2 methyl CpG binding protein 2 0.092
Ep400 E1A binding protein p400 0.092
Pou5f1 POU domain, class 5, transcription factor 1 0.091
Rif1 Rap1 interacting factor 1 homolog (yeast) 0.091
Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.091
Thoc2 THO complex 2 0.090
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.087
Cbx1 chromobox homolog 1 (Drosophila HP1 beta) 0.087
Ctcf CCCTC-binding factor 0.086
Rnpc3 RNA-binding region (RNP1, RRM) containing 3 0.086
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.082
Wdr5 WD repeat domain 5 0.082
Atxn7 ataxin 7 0.078
Ddx10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 0.077
Baz1b bromodomain adjacent to zinc finger domain, 1B 0.076
E2f1 E2F transcription factor 1 0.075
Bcor BCL6 interacting corepressor 0.073
Msl2 male-specific lethal 2 homolog (Drosophila) 0.073
Pcm1 pericentriolar material 1 0.068
Pole polymerase (DNA directed), epsilon 0.063
Bclaf1 BCL2-associated transcription factor 1 0.062
Arid1b AT rich interactive domain 1B (SWI-like) 0.062
Hnrnpab heterogeneous nuclear ribonucleoprotein A/B 0.061
Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 0.060
Prim1 DNA primase, p49 subunit 0.059
Kdm1a lysine (K)-specific demethylase 1A 0.056
Rfc5 replication factor C (activator 1) 5 0.055
Sae1 SUMO1 activating enzyme subunit 1 0.054
Ppig peptidyl-prolyl isomerase G (cyclophilin G) 0.051
Ubap2 ubiquitin-associated protein 2 0.051
Epc2 enhancer of polycomb homolog 2 (Drosophila) 0.051
Trrap transformation/transcription domain-associated protein 0.050
Rsbn1 rosbin, round spermatid basic protein 1 0.050
Smc6 structural maintenance of chromosomes 6 0.050
Csrp2bp cysteine and glycine-rich protein 2 binding protein 0.047
Ythdc1 YTH domain containing 1 0.047
Rb1 retinoblastoma 1 0.045
Klhl24 kelch-like 24 (Drosophila) 0.045
Mael maelstrom homolog (Drosophila) 0.045
Cbx3 chromobox homolog 3 (Drosophila HP1 gamma) 0.045
Rrm1 ribonucleotide reductase M1 0.043
Cdca5 cell division cycle associated 5 0.043
Csnk2a1 casein kinase 2, alpha 1 polypeptide 0.042
Rbm26 RNA binding motif protein 26 0.042
Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 0.041
Nup153 nucleoporin 153 0.041
Chaf1a chromatin assembly factor 1, subunit A (p150) 0.040
Hmgb1 high mobility group box 1 0.040
Creb1 cAMP responsive element binding protein 1 0.040
Rad21 RAD21 homolog (S. pombe) 0.040
Usp7 ubiquitin specific peptidase 7 0.039
Hnrnpu heterogeneous nuclear ribonucleoprotein U 0.039
Rrm2 ribonucleotide reductase M2 0.039
Ddx46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.039
Hnrnpd heterogeneous nuclear ribonucleoprotein D 0.039
Nanog Nanog homeobox 0.038
Mga MAX gene associated 0.038
Hcfc1 host cell factor C1 0.038
Brca2 breast cancer 2 0.037
Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.036
Dmap1 DNA methyltransferase 1-associated protein 1 0.036
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.035
Mms22l MMS22-like, DNA repair protein 0.034
L3mbtl2 l(3)mbt-like 2 (Drosophila) 0.034
Anapc5 anaphase-promoting complex subunit 5 0.034
Sp1 trans-acting transcription factor 1 0.033
Max Max protein 0.033
Dhx15 DEAH (Asp-Glu-Ala-His) box polypeptide 15 0.033
Pparg peroxisome proliferator activated receptor gamma 0.032
Cdc6 cell division cycle 6 homolog (S. cerevisiae) 0.032
Bod1l biorientation of chromosomes in cell division 1-like 0.030
Ing3 inhibitor of growth family, member 3 0.029
Hells helicase, lymphoid specific 0.028
Cnot4 CCR4-NOT transcription complex, subunit 4 0.028
Cdc73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.028
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Rattus norvegicus
Name Description Probability Func Analog Organism