The network for 'cellular response to chemical stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to chemical stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
FAR1 Far1p 0.992
STE11 Ste11p 0.975
KSP1 Ksp1p 0.948
FUS3 Fus3p 0.945
STE4 Ste4p 0.923
SWE1 Swe1p 0.888
STE2 Ste2p 0.843
AGA1 Aga1p 0.826
PPH21 Pph21p 0.822
STE5 Ste5p 0.795
HOG1 Hog1p 0.787
KSS1 Kss1p 0.780
FAR11 Far11p 0.724
SNF2 Snf2p 0.720
YAP1 Yap1p 0.686
STE7 Ste7p 0.669
SLT2 Slt2p 0.666
AGA2 Aga2p 0.663
RPN4 Rpn4p 0.655
HSP42 Hsp42p 0.631
UBP15 Ubp15p 0.629
UFD2 Ufd2p 0.621
SSE2 Sse2p 0.617
SSD1 Ssd1p 0.616
FUS1 Fus1p 0.610
HSP104 Hsp104p 0.604
STE50 Ste50p 0.557
STE18 Ste18p 0.549
CDC24 Cdc24p 0.544
HOF1 Hof1p 0.544
YPT1 Ypt1p 0.537
FIG2 Fig2p 0.532
MYO2 Myo2p 0.525
GFA1 Gfa1p 0.523
MSG5 Msg5p 0.516
PTC1 Ptc1p 0.512
CDC4 Cdc4p 0.505
FKH1 Fkh1p 0.505
BEM1 Bem1p 0.499
RTG3 Rtg3p 0.498
UGA1 Uga1p 0.487
CDC55 Cdc55p 0.486
SGT2 Sgt2p 0.478
CYC8 Cyc8p 0.478
ROM2 Rom2p 0.477
CHD1 Chd1p 0.474
GPR1 Gpr1p 0.473
ATG1 Atg1p 0.469
CLA4 Cla4p 0.459
MKS1 Mks1p 0.455
MKK2 Mkk2p 0.452
TRX2 Trx2p 0.452
ARO1 Aro1p 0.450
YAK1 Yak1p 0.450
HAP3 Hap3p 0.449
MSN2 Msn2p 0.446
MFA1 Mfa1p 0.437
TPK1 Tpk1p 0.435
NBP2 Nbp2p 0.433
HTA2 Hta2p 0.430
BMH1 Bmh1p 0.427
TOR1 Tor1p 0.427
OTU1 Otu1p 0.425
TSA2 Tsa2p 0.425
VAC7 Vac7p 0.425
RRI1 Rri1p 0.418
SNF6 Snf6p 0.410
GAL11 Gal11p 0.410
SIC1 Sic1p 0.402
GCD7 Gcd7p 0.399
SKP1 Skp1p 0.396
SIT4 Sit4p 0.395
GPA2 Gpa2p 0.389
ARP8 Arp8p 0.387
SCH9 Sch9p 0.383
GRX4 Grx4p 0.381
SST2 Sst2p 0.378
OYE2 Oye2p 0.375
DIA2 Dia2p 0.375
SHP1 Shp1p 0.369
AFT1 Aft1p 0.368
CLB2 Clb2p 0.367
PHO80 Pho80p 0.362
FIG4 Fig4p 0.362
YPK2 Ypk2p 0.361
SIR2 Sir2p 0.361
CLB3 Clb3p 0.360
AXL1 Axl1p 0.358
IRE1 Ire1p 0.357
MGA2 Mga2p 0.354
PMR1 Pmr1p 0.354
CKB1 Ckb1p 0.350
CDC48 Cdc48p 0.349
BCY1 Bcy1p 0.347
UBA1 Uba1p 0.347
UTP22 Utp22p 0.344
OM45 Om45p 0.343
GRE3 Gre3p 0.341
UBA4 Uba4p 0.334
DOT6 Dot6p 0.334
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
vab-3 Protein VAB-3 0.958
abu-11 Protein ABU-11 0.896
tag-320 Protein TAG-320 0.843
abu-15 Protein ABU-15 0.741
nhr-67 Protein NHR-67 0.704
par-5 Protein PAR-5 0.695
egl-44 Protein EGL-44 0.579
egl-18 Protein EGL-18 0.570
hsp-70 Protein HSP-70 0.558
pqn-54 Protein PQN-54 0.552
peb-1 Protein PEB-1 0.541
plc-1 Protein PLC-1 0.536
ifg-1 Protein IFG-1 0.536
abu-6 Protein ABU-6 0.530
hsp-16.41 Protein HSP-16.41 0.510
daf-11 Protein DAF-11 0.504
mat-3 Protein MAT-3 0.471
ZK686.3 Protein ZK686.3 0.439
F53F10.2 Protein F53F10.2 0.435
hsp-16.1 Protein HSP-16.1 0.422
ufd-2 Protein UFD-2 0.422
npl-4.2 Protein NPL-4.2 0.419
sup-17 Protein SUP-17 0.410
unc-52 Protein UNC-52 0.404
daf-1 Protein DAF-1 0.397
ace-3 Protein ACE-3 0.393
acs-4 Protein ACS-4 0.393
egg-6 Protein EGG-6 0.387
lmn-1 Protein LMN-1 0.379
unc-62 Protein UNC-62 0.376
F44E5.4 Protein F44E5.4 0.361
hsp-16.2 Protein HSP-16.2 0.358
daf-14 Protein DAF-14 0.353
unc-53 Protein UNC-53 0.331
ccch-1 Protein CCCH-1 0.328
pry-1 Protein PRY-1 0.318
akt-1 Protein AKT-1 0.302
egl-8 Protein EGL-8 0.302
amx-2 Protein AMX-2 0.296
H43E16.1 Protein H43E16.1 0.295
abu-1 Protein ABU-1 0.294
gdh-1 Protein GDH-1 0.285
spp-10 Protein SPP-10 0.277
atg-2 Protein ATG-2 0.274
abu-10 Protein ABU-10 0.274
cam-1 Protein CAM-1 0.271
daf-3 Protein DAF-3 0.266
unc-73 Protein UNC-73 0.266
tbb-2 Protein TBB-2 0.265
let-756 Protein LET-756 0.255
eat-6 Protein EAT-6 0.255
unc-104 Protein UNC-104 0.250
nucb-1 Protein NUCB-1 0.249
zyg-8 Protein ZYG-8 0.248
ptr-14 Protein PTR-14 0.242
tba-4 Protein TBA-4 0.242
CELE_F42F12.3 Protein F42F12.3 0.241
nra-4 Protein NRA-4 0.240
csn-5 Protein CSN-5 0.239
ptr-23 Protein PTR-23 0.238
ceh-20 Protein CEH-20 0.235
apc-2 Protein APC-2 0.230
pkc-3 Protein PKC-3 0.228
CELE_C01G6.5 Protein C01G6.5 0.228
abu-14 Protein ABU-14 0.224
lsy-22 Protein LSY-22 0.224
egal-1 Protein EGAL-1 0.222
ttx-1 Protein TTX-1 0.219
che-3 Protein CHE-3 0.219
hsp-3 Protein HSP-3 0.218
bar-1 Protein BAR-1 0.215
lys-1 Protein LYS-1 0.211
apr-1 Protein APR-1 0.210
ifb-1 Protein IFB-1 0.210
unc-86 Protein UNC-86 0.210
C05D10.4 Protein C05D10.4 0.209
hlh-2 Protein HLH-2 0.206
hsp-16.48 Protein HSP-16.48 0.205
imp-2 Protein IMP-2 0.201
W01A11.1 Protein W01A11.1 0.200
pkg-1 Protein PKG-1 0.200
cgh-1 Protein CGH-1 0.200
CELE_C12D8.1 Protein C12D8.1 0.199
tag-232 Protein TAG-232 0.198
sur-2 Protein SUR-2 0.197
ina-1 Protein INA-1 0.196
uig-1 Protein UIG-1 0.195
inx-19 Protein INX-19 0.194
vit-2 Protein VIT-2 0.194
zfp-1 Protein ZFP-1 0.194
cdf-1 Protein CDF-1 0.193
cts-1 Protein CTS-1 0.191
plc-3 Protein PLC-3 0.191
cul-2 Protein CUL-2 0.189
lec-10 Protein LEC-10 0.188
uggt-1 Protein UGGT-1 0.186
che-1 Protein CHE-1 0.186
trap-2 Protein TRAP-2 0.182
sax-3 Protein SAX-3 0.181
daf-7 Protein DAF-7 0.180
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Danio rerio
Name Description Probability Func Analog Organism
spry4 sprouty (Drosophila) homolog 4 0.982
tbx1 T-box 1 0.980
fgf3 fibroblast growth factor 3 0.961
shha sonic hedgehog a 0.947
fn1 fibronectin 1 0.844
ndr2 nodal-related 2 0.673
cmyb transcription factor cmyb 0.630
tp53 tumor protein p53 0.598
dusp6 dual specificity phosphatase 6 0.587
fabp11a fatty acid binding protein 11a 0.585
chd chordin 0.581
hspa5 heat shock protein 5 0.577
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.565
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.563
cdkn1c cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.535
igf1ra insulin-like growth factor 1a receptor 0.535
wnt11r wingless-type MMTV integration site family, member 11, related 0.522
sparc secreted acidic cysteine rich glycoprotein 0.520
etv5b ets variant 5b 0.518
cdh2 cadherin 2, neuronal 0.515
wnt8b wingless-type MMTV integration site family, member 8b 0.514
sox9a SRY-box containing gene 9a 0.512
cav1 caveolin 1 0.507
foxi1 forkhead box I1 0.501
nrp2b neuropilin 2b 0.492
cdh1 cadherin 1, epithelial 0.488
igf1 insulin-like growth factor 1 0.476
apoeb apolipoprotein Eb 0.463
cyp1a cytochrome P450, family 1, subfamily A 0.456
esr2a estrogen receptor 2a 0.453
wnt10a wingless-type MMTV integration site family, member 10a 0.451
fgf8a fibroblast growth factor 8 a 0.442
cyp26a1 cytochrome P450, subfamily XXVIA, polypeptide 1 0.439
cdh23 cadherin-like 23 0.432
gata4 GATA-binding protein 4 0.416
pax6a paired box gene 6a 0.415
gdf6a growth differentiation factor 6a 0.406
wt1a wilms tumor 1a 0.405
sox32 SRY-box containing gene 32 0.389
col5a1 procollagen, type V, alpha 1 0.388
ctgf connective tissue growth factor 0.386
wnt5b wingless-type MMTV integration site family, member 5b 0.385
sall1a sal-like 1a (Drosophila) 0.377
notch1a notch homolog 1a 0.373
snai1a snail homolog 1a (Drosophila) 0.368
boc brother of CDO 0.364
flh floating head 0.363
cxcr4b chemokine (C-X-C motif), receptor 4b 0.361
ptch1 patched 1 0.359
pomca proopiomelanocortin a 0.358
pdgfaa platelet-derived growth factor alpha a 0.354
bmp2a bone morphogenetic protein 2a 0.350
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.349
btg2 B-cell translocation gene 2 0.346
zic2a zic family member 2 (odd-paired homolog, Drosophila), a 0.343
tbx20 T-box 20 0.341
pitx3 paired-like homeodomain transcription factor 3 0.340
zgc:64051 zgc:64051 0.339
srf serum response factor 0.339
igf2b insulin-like growth factor 2b 0.337
rarab retinoic acid receptor, alpha b 0.336
oep one-eyed pinhead 0.324
dld deltaD 0.321
robo3 roundabout homolog 3 0.312
mef2ca myocyte enhancer factor 2ca 0.303
gli2a GLI-Kruppel family member GLI2a 0.300
bmp4 bone morphogenetic protein 4 0.298
sox9b SRY-box containing gene 9b 0.297
tuba1 tubulin, alpha 1 0.295
runx2a runt-related transcription factor 2a 0.294
fzd7b frizzled homolog 7b 0.293
nanos3 nanos homolog 3 0.292
tgfb1a transforming growth factor, beta 1a 0.289
fbn2b fibrillin 2b 0.288
sema3aa semaphorin 3aa 0.285
coro1a coronin, actin binding protein, 1A 0.284
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.283
tal1 T-cell acute lymphocytic leukemia 1 0.282
stat5.1 signal transducer and activator of transcription 5.1 0.280
vasa vasa homolog 0.279
nkx3.2 NK3 homeobox 2 0.278
fras1 Fraser syndrome 1 0.275
wnt2 wingless-type MMTV integration site family member 2 0.274
hcrt hypocretin (orexin) neuropeptide precursor 0.274
ptena phosphatase and tensin homolog A 0.272
nkx2.5 NK2 transcription factor related 5 0.271
gpia glucose phosphate isomerase a 0.268
plcg1 phospholipase C, gamma 1 0.268
pycard PYD and CARD domain containing 0.268
slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 0.266
chrna1 cholinergic receptor, nicotinic, alpha polypeptide 1 0.265
cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.265
bmp2b bone morphogenetic protein 2b 0.264
hdac4 histone deacetylase 4 0.261
cyp19a1a cytochrome P450, family 19, subfamily A, polypeptide 1a 0.260
mmp9 matrix metalloproteinase 9 0.260
neurod neurogenic differentiation 0.258
cyp3a65 cytochrome P450, family 3, subfamily A, polypeptide 65 0.258
il17rd interleukin 17 receptor D 0.257
dusp2 dual specificity phosphatase 2 0.256
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Drosophila melanogaster
Name Description Probability Func Analog Organism
EcR Ecdysone receptor 0.997
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.997
Egfr Epidermal growth factor receptor 0.984
bsk basket 0.973
shn schnurri 0.958
InR Insulin-like receptor 0.956
Ubqn Ubiquilin 0.954
Sir2 CG5216 gene product from transcript CG5216-RA 0.953
Atg1 Autophagy-specific gene 1 0.944
Stat92E Signal-transducer and activator of transcription protein at 92E 0.929
par-1 CG8201 gene product from transcript CG8201-RA 0.928
Mad Mothers against dpp 0.928
S6k RPS6-p70-protein kinase 0.926
hep hemipterous 0.859
dm diminutive 0.858
p53 CG33336 gene product from transcript CG33336-RB 0.852
put punt 0.843
drk downstream of receptor kinase 0.815
nej nejire 0.782
ago archipelago 0.745
htl heartless 0.730
woc without children 0.728
phl pole hole 0.711
tkv thickveins 0.710
csw corkscrew 0.703
Tl Toll 0.692
Lis-1 Lissencephaly-1 0.691
Rel Relish 0.689
fl(2)d female lethal d 0.682
dally division abnormally delayed 0.682
foxo forkhead box, sub-group O 0.675
rictor rapamycin-insensitive companion of Tor 0.674
fkh fork head 0.653
Pten CG5671 gene product from transcript CG5671-RB 0.646
Nrg Neuroglian 0.631
Kr-h1 Kruppel homolog 1 0.630
LanA Laminin A 0.616
Ras85D Ras oncogene at 85D 0.612
NFAT NFAT homolog 0.611
Smox Smad on X 0.610
Akt1 CG4006 gene product from transcript CG4006-RA 0.608
pnt pointed 0.601
argos CG4531 gene product from transcript CG4531-RA 0.590
Fmr1 CG6203 gene product from transcript CG6203-RC 0.581
Sfmbt Scm-related gene containing four mbt domains 0.578
p38b CG7393 gene product from transcript CG7393-RA 0.573
Rab7 Rab-protein 7 0.572
Med Medea 0.558
Pvr PDGF- and VEGF-receptor related 0.555
N Notch 0.553
btz barentsz 0.552
hipk homeodomain interacting protein kinase 0.541
eve even skipped 0.539
klu klumpfuss 0.534
mbc myoblast city 0.531
scny scrawny 0.524
chico CG5686 gene product from transcript CG5686-RB 0.523
ap apterous 0.507
Moe Moesin 0.504
Cdc42 CG12530 gene product from transcript CG12530-RA 0.498
Src42A Src oncogene at 42A 0.498
cbt cabut 0.487
fru fruitless 0.471
krz kurtz 0.471
emc extra macrochaetae 0.465
hth homothorax 0.462
Rac1 CG2248 gene product from transcript CG2248-RA 0.459
pan pangolin 0.458
Stam Signal transducing adaptor molecule 0.450
rpr reaper 0.427
stmA stambha A 0.417
ttv tout-velu 0.416
wts warts 0.414
G-oalpha47A G protein oalpha 47A 0.411
sax saxophone 0.406
Rho1 CG8416 gene product from transcript CG8416-RB 0.406
shi shibire 0.400
eya eyes absent 0.395
ci cubitus interruptus 0.394
jeb jelly belly 0.389
Mpk2 CG5475 gene product from transcript CG5475-RB 0.382
shg shotgun 0.377
CycA Cyclin A 0.376
Tbh Tyramine beta hydroxylase 0.375
gcl germ cell-less 0.373
skpA CG16983 gene product from transcript CG16983-RD 0.370
dbr debra 0.363
gig gigas 0.361
retn retained 0.359
slmb supernumerary limbs 0.359
Mhc Myosin heavy chain 0.358
Pez CG9493 gene product from transcript CG9493-RA 0.358
TBPH CG10327 gene product from transcript CG10327-RC 0.355
Pink1 PTEN-induced putative kinase 1 0.353
path pathetic 0.352
Acsl Acyl-CoA synthetase long-chain 0.349
CG2924 CG2924 gene product from transcript CG2924-RA 0.346
CG42630 CG42630 gene product from transcript CG42630-RA 0.342
dlp dally-like 0.330
CycG Cyclin G 0.319
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism