The network for 'regulation of proteolysis involved in cellular protein catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of proteolysis involved in cellular protein catabolic process

Any process that modulates the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
CDC55 Cdc55p 0.902
CDC20 Cdc20p 0.693
CTF13 Ctf13p 0.593
PPH21 Pph21p 0.542
SLK19 Slk19p 0.462
RAD23 Rad23p 0.441
CDC26 Cdc26p 0.432
YBP2 Ybp2p 0.413
MAD2 Mad2p 0.406
CDC16 Cdc16p 0.403
BUB1 Bub1p 0.396
PPH22 Pph22p 0.390
CSE4 Cse4p 0.372
CBF1 Cbf1p 0.302
UBR1 Ubr1p 0.284
RPT6 Rpt6p 0.264
GIP2 Gip2p 0.263
BUB3 Bub3p 0.262
CDC23 Cdc23p 0.246
RPT2 Rpt2p 0.238
TIP41 Tip41p 0.209
PIG2 Pig2p 0.189
ECO1 Eco1p 0.177
CDC34 Cdc34p 0.165
HHF2 Hhf2p 0.151
YAP1 Yap1p 0.148
RTS1 Rts1p 0.134
ECM29 Ecm29p 0.130
PPZ1 Ppz1p 0.126
MND2 Mnd2p 0.124
RPT1 Rpt1p 0.120
MCM21 Mcm21p 0.113
RPN3 Rpn3p 0.110
VPS60 Vps60p 0.110
NBL1 Nbl1p 0.107
DOC1 Doc1p 0.107
BMH2 Bmh2p 0.106
VHS3 Vhs3p 0.106
GLC7 Glc7p 0.105
KIP1 Kip1p 0.105
RPN14 Rpn14p 0.101
HAL5 Hal5p 0.100
RPN10 Rpn10p 0.098
MAD1 Mad1p 0.095
KSP1 Ksp1p 0.095
RPT3 Rpt3p 0.094
MGA2 Mga2p 0.093
IML3 Iml3p 0.092
PDS1 Pds1p 0.091
HHO1 Hho1p 0.086
RPN7 Rpn7p 0.084
UBC13 Ubc13p 0.083
CDC27 Cdc27p 0.083
APC2 Apc2p 0.080
SKP1 Skp1p 0.078
MNN9 Mnn9p 0.078
APP1 App1p 0.077
RPT4 Rpt4p 0.074
PRE2 Pre2p 0.073
CDC4 Cdc4p 0.072
RPN9 Rpn9p 0.071
CHL4 Chl4p 0.069
PKC1 Pkc1p 0.069
EAF1 Eaf1p 0.068
MAD3 Mad3p 0.066
RPN2 Rpn2p 0.064
CTF3 Ctf3p 0.061
ASE1 Ase1p 0.061
SDS22 Sds22p 0.059
CDC28 Cdc28p 0.058
UBR2 Ubr2p 0.056
RHO1 Rho1p 0.055
PPQ1 Ppq1p 0.055
PTI1 Pti1p 0.054
RLM1 Rlm1p 0.054
GLN3 Gln3p 0.054
IRC15 Irc15p 0.053
SWM1 Swm1p 0.053
YAK1 Yak1p 0.053
YPI1 Ypi1p 0.052
PSP1 Psp1p 0.051
KIN3 Kin3p 0.050
SWC4 Swc4p 0.050
SLX8 Slx8p 0.050
MOB1 Mob1p 0.049
RPN1 Rpn1p 0.049
NSL1 Nsl1p 0.049
RAD61 Rad61p 0.049
TBS1 Tbs1p 0.046
RPN12 Rpn12p 0.046
NPL4 Npl4p 0.045
APC11 Apc11p 0.045
APC4 Apc4p 0.044
CDC31 Cdc31p 0.043
UFD2 Ufd2p 0.043
UFO1 Ufo1p 0.043
UBP6 Ubp6p 0.043
FPK1 Fpk1p 0.042
BCK2 Bck2p 0.042
RMD5 Rmd5p 0.042
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
imb-2 Protein IMB-2 0.186
ubq-1 Protein UBQ-1 0.065
rfc-2 Protein RFC-2 0.049
pup-2 Protein PUP-2 0.038
zyg-9 Protein ZYG-9 0.037
htz-1 Protein HTZ-1 0.037
rnr-1 Protein RNR-1 0.037
mex-5 Protein MEX-5 0.036
his-6 Protein HIS-6 0.033
hgrs-1 Protein HGRS-1 0.029
rpn-7 Protein RPN-7 0.028
stam-1 Protein STAM-1 0.027
cul-1 Protein CUL-1 0.026
rpn-6.1 Protein RPN-6.1 0.022
ima-3 Protein IMA-3 0.020
egl-18 Protein EGL-18 0.020
R11A8.7 Protein R11A8.7 0.019
spk-1 Protein SPK-1 0.018
rod-1 Protein ROD-1 0.017
pry-1 Protein PRY-1 0.016
W09D10.1 Protein W09D10.1 0.016
F18A1.8 Protein F18A1.8 0.016
hsp-1 Protein HSP-1 0.016
klp-16 Protein KLP-16 0.015
hcp-6 Protein HCP-6 0.015
his-45 Protein HIS-45 0.015
rad-26 Protein RAD-26 0.014
ect-2 Protein ECT-2 0.014
rpn-2 Protein RPN-2 0.014
air-2 Protein AIR-2 0.014
his-42 Protein HIS-42 0.013
K08E3.5 Protein K08E3.5 0.013
tiar-1 Protein TIAR-1 0.013
T08A11.2 Protein T08A11.2 0.013
let-502 Protein LET-502 0.012
mex-3 Protein MEX-3 0.012
T22F3.2 Protein T22F3.2 0.012
dsh-2 Protein DSH-2 0.011
ZK507.6 Protein ZK507.6 0.011
T22C1.1 Protein T22C1.1 0.011
atg-18 Protein ATG-18 0.011
cdk-9 Protein CDK-9 0.011
tba-2 Protein TBA-2 0.011
gyg-2 Protein GYG-2 0.010
cdc-48.2 Protein CDC-48.2 0.010
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
ccnb1 cyclin B1 0.584
cdc20 cell division cycle 20 homolog 0.396
kif23 kinesin family member 23 0.365
plk1 polo-like kinase 1 (Drosophila) 0.354
wnt4a wingless-type MMTV integration site family, member 4a 0.309
tacc3 transforming, acidic coiled-coil containing protein 3 0.236
cdt1 chromatin licensing and DNA replication factor 1 0.219
hspa4b heat shock protein 4b 0.213
smad5 MAD homolog 5 (Drosophila) 0.212
psmb5 proteasome (prosome, macropain) subunit, beta type, 5 0.207
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.203
zgc:152830 zgc:152830 0.195
csnk1g2a casein kinase 1, gamma 2a 0.189
cstf1 cleavage stimulation factor, 3' pre-RNA, subunit 1 0.189
ccnb2 cyclin B2 0.168
ing5b inhibitor of growth family, member 5b 0.166
si:ch211-69g19.2 si:ch211-69g19.2 0.157
aurkb aurora kinase B 0.155
csnk1db casein kinase 1, delta b 0.151
pbrm1l polybromo 1, like 0.147
baxa bcl2-associated X protein, a 0.146
usp4 ubiquitin specific protease 4 (proto-oncogene) 0.145
ccna2 cyclin A2 0.145
eif3s10 eukaryotic translation initiation factor 3, subunit 10 (theta) 0.142
gro2 groucho 2 0.137
rplp0 ribosomal protein, large, P0 0.136
tp53 tumor protein p53 0.131
bag6 BCL2-associated athanogene 6 0.130
foxd3 forkhead box D3 0.129
trim71 tripartite motif-containing 71 0.126
cand1 cullin-associated and neddylation-dissociated 1 0.123
tax1bp1b Tax1 (human T-cell leukemia virus type I) binding protein 1b 0.123
extl3 exostoses (multiple)-like 3 0.122
dusp1 dual specificity phosphatase 1 0.121
psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 0.119
psmd11b proteasome (prosome, macropain) 216S subunit, non-ATPase, 11b 0.118
srsf1a serine/arginine-rich splicing factor 1a 0.117
senp3a SUMO1/sentrin/SMT3 specific peptidase 3a 0.116
dvl2 dishevelled, dsh homolog 2 (Drosophila) 0.115
usp5 ubiquitin specific protease 5 0.108
rasl11b RAS-like, family 11, member B 0.107
btg2 B-cell translocation gene 2 0.107
zgc:56200 zgc:56200 0.106
polr2b polymerase (RNA) II (DNA directed) polypeptide B 0.105
zgc:55448 zgc:55448 0.104
ctsba cathepsin B, a 0.103
fgf3 fibroblast growth factor 3 0.103
gmnn geminin, DNA replication inhibitor 0.102
gins3 GINS complex subunit 3 0.099
sox32 SRY-box containing gene 32 0.099
ndc80 NDC80 homolog, kinetochore complex component (S. cerevisiae) 0.098
rpl4 ribosomal protein L4 0.098
ihha Indian hedgehog homolog a 0.096
hnrnpk heterogeneous nuclear ribonucleoprotein K 0.096
aurka aurora kinase A 0.094
supt5h suppressor of Ty 5 homolog (S. cerevisiae) 0.094
arid4a AT rich interactive domain 4A (RBP1-like) 0.092
ext2 exostoses (multiple) 2 0.091
birc5a baculoviral IAP repeat-containing 5a 0.090
sumo3a SMT3 suppressor of mif two 3 homolog 3a 0.089
hspa8 heat shock protein 8 0.088
eif5a eukaryotic translation initiation factor 5A 0.086
esco2 establishment of cohesion 1 homolog 2 0.084
kpna2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.080
gna13a guanine nucleotide binding protein (G protein), alpha 13a 0.080
LOC100536090 targeting protein for Xklp2-B-like 0.080
zgc:77262 zgc:77262 0.079
bactin2 bactin2 0.079
nrp1a neuropilin 1a 0.079
dcst1 DC-STAMP domain containing 1 0.077
zfand5b zinc finger, AN1-type domain 5b 0.074
cpsf3l cleavage and polyadenylation specific factor 3-like 0.074
prkrir protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 0.073
cdca8 cell division cycle associated 8 0.073
ck2b casein kinase 2 beta 0.072
ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.070
grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.069
ercc2 excision repair cross-complementing rodent repair deficiency, complementation group 2 0.069
nup88 nucleoporin 88 0.068
rtkn2 rhotekin 2 0.067
tpt1 tumor protein, translationally-controlled 1 0.067
ved ventrally expressed dharma/bozozok antagonist 0.067
suv39h1b suppressor of variegation 3-9 homolog 1b 0.067
zgc:55891 zgc:55891 0.066
orc1 origin recognition complex, subunit 1 0.066
med24 mediator complex subunit 24 0.066
nap1l1 nucleosome assembly protein 1, like 1 0.066
clptm1 cleft lip and palate associated transmembrane protein 1 0.066
psmd6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.066
si:ch211-244o22.2 si:ch211-244o22.2 0.065
smo smoothened homolog (Drosophila) 0.065
dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.065
ypel3 yippee-like 3 0.064
zgc:111944 zgc:111944 0.062
papolg poly(A) polymerase gamma 0.061
psmd4b proteasome (prosome, macropain) 26S subunit, non-ATPase, 4b 0.061
pif1 PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) 0.061
mapk3 mitogen-activated protein kinase 3 0.060
ncapd2 non-SMC condensin I complex, subunit D2 0.060
aldoaa aldolase a, fructose-bisphosphate, a 0.059
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Ras85D Ras oncogene at 85D 0.702
smo smoothened 0.694
tefu telomere fusion 0.602
CycB Cyclin B 0.509
brm brahma 0.451
Egfr Epidermal growth factor receptor 0.428
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.366
thr three rows 0.337
CycA Cyclin A 0.285
Iswi Imitation SWI 0.237
ncd non-claret disjunctional 0.207
sqh spaghetti squash 0.202
hpo hippo 0.200
nej nejire 0.192
Rpt1 CG1341 gene product from transcript CG1341-RA 0.178
dup double parked 0.175
CG30382 CG30382 gene product from transcript CG30382-RB 0.175
gwl greatwall 0.165
Rpt3 CG16916 gene product from transcript CG16916-RA 0.156
Doa Darkener of apricot 0.156
lgs legless 0.148
CG13349 CG13349 gene product from transcript CG13349-RA 0.144
UbcD2 Ubiquitin conjugating enzyme 2 0.143
Su(H) Suppressor of Hairless 0.141
CG11347 CG11347 gene product from transcript CG11347-RE 0.137
cav caravaggio 0.130
Pros45 CG1489 gene product from transcript CG1489-RA 0.130
Pros25 Proteasome 25kD subunit 0.128
Akt1 CG4006 gene product from transcript CG4006-RA 0.125
Su(var)205 Suppressor of variegation 205 0.121
CSN3 COP9 complex homolog subunit 3 0.119
Mcm10 Sensitized chromosome inheritance modifier 19 0.111
CG12321 CG12321 gene product from transcript CG12321-RA 0.111
cdc16 CG6759 gene product from transcript CG6759-RA 0.103
jub Ajuba LIM protein 0.099
ci cubitus interruptus 0.098
krz kurtz 0.097
Rpn9 CG10230 gene product from transcript CG10230-RB 0.096
Hsc70-4 Heat shock protein cognate 4 0.096
Pp1-87B Protein phosphatase 1 at 87B 0.092
Cul-5 Cullin-5 0.092
Pros35 Proteasome 35kD subunit 0.089
endos endosulfine 0.086
Rpn11 CG18174 gene product from transcript CG18174-RA 0.086
Rpn6 Proteasome p44.5 subunit 0.084
cdc2 CG5363 gene product from transcript CG5363-RA 0.082
N Notch 0.082
Top1 Topoisomerase 1 0.080
shg shotgun 0.078
Sep2 Septin-2 0.077
Cul-3 Cullin-3 0.076
Bap55 Brahma associated protein 55kD 0.071
Shc SHC-adaptor protein 0.071
Tbp-1 Tat-binding protein-1 0.071
SF2 CG6987 gene product from transcript CG6987-RA 0.070
p53 CG33336 gene product from transcript CG33336-RB 0.065
CG9986 CG9986 gene product from transcript CG9986-RA 0.065
drk downstream of receptor kinase 0.065
bel belle 0.064
loqs loquacious 0.064
Cap-G CG34438 gene product from transcript CG34438-RF 0.064
Mov34 CG3416 gene product from transcript CG3416-RA 0.063
arm armadillo 0.062
polo CG12306 gene product from transcript CG12306-RA 0.061
Rpt4 CG3455 gene product from transcript CG3455-RA 0.059
CSN5 COP9 complex homolog subunit 5 0.058
Rpn1 CG7762 gene product from transcript CG7762-RA 0.058
E(z) Enhancer of zeste 0.056
smt3 CG4494 gene product from transcript CG4494-RA 0.055
Krn Keren 0.055
Pros26.4 Proteasome 26S subunit subunit 4 ATPase 0.055
dap dacapo 0.054
mts microtubule star 0.053
Act5C Actin 5C 0.053
chb chromosome bows 0.051
Cortactin CG3637 gene product from transcript CG3637-RA 0.050
RYBP Ring and YY1 Binding Protein 0.050
brat brain tumor 0.050
slmb supernumerary limbs 0.050
betaTub60D beta-Tubulin at 60D 0.049
edl ETS-domain lacking 0.049
bun bunched 0.049
Pros28.1 Proteasome 28kD subunit 1 0.049
spas spastin 0.048
Miro Mitochondrial Rho 0.047
Cenp-C CG31258 gene product from transcript CG31258-RA 0.047
wls wntless 0.046
p47 CG11139 gene product from transcript CG11139-RA 0.045
sds22 CG5851 gene product from transcript CG5851-RA 0.045
Psf2 CG18013 gene product from transcript CG18013-RA 0.045
Psn Presenilin 0.045
CG4266 CG4266 gene product from transcript CG4266-RA 0.044
Art1 Arginine methyltransferase 1 0.044
Uev1A CG10640 gene product from transcript CG10640-RA 0.044
CG6961 CG6961 gene product from transcript CG6961-RA 0.044
nbs CG6754 gene product from transcript CG6754-RC 0.044
gbb glass bottom boat 0.043
bam bag of marbles 0.043
Hrb27C Heterogeneous nuclear ribonucleoprotein at 27C 0.043
tsr twinstar 0.043
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
UBC ubiquitin C 1.000
TP53 tumor protein p53 0.999
CDC20 cell division cycle 20 homolog (S. cerevisiae) 0.998
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.994
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.990
ANAPC7 anaphase promoting complex subunit 7 0.989
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 0.986
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 0.985
RNF11 ring finger protein 11 0.982
RB1 retinoblastoma 1 0.979
GSK3B glycogen synthase kinase 3 beta 0.979
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.970
BUB1B budding uninhibited by benzimidazoles 1 homolog beta (yeast) 0.968
CSNK1E casein kinase 1, epsilon 0.966
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.964
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 0.961
SMAD3 SMAD family member 3 0.957
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.956
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.952
SMAD2 SMAD family member 2 0.950
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 0.941
SMAD1 SMAD family member 1 0.933
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 0.927
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.922
SMAD5 SMAD family member 5 0.902
SMAD4 SMAD family member 4 0.900
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.889
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 0.876
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.875
UBE2D2 ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) 0.875
BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) 0.867
UBQLN1 ubiquilin 1 0.847
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.843
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.828
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.808
AXIN1 axin 1 0.802
PML promyelocytic leukemia 0.801
DAXX death-domain associated protein 0.748
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.746
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.740
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.705
TBP TATA box binding protein 0.694
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.688
UBE2D3 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) 0.685
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.681
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.672
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.669
ANAPC11 anaphase promoting complex subunit 11 0.665
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.660
SOCS1 suppressor of cytokine signaling 1 0.657
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 0.650
CDK2 cyclin-dependent kinase 2 0.625
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 0.605
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 0.588
ANAPC4 anaphase promoting complex subunit 4 0.586
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.570
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.564
RAD23B RAD23 homolog B (S. cerevisiae) 0.563
PIAS4 protein inhibitor of activated STAT, 4 0.560
PLK1 polo-like kinase 1 0.560
PTK2 PTK2 protein tyrosine kinase 2 0.537
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.531
OTUB1 OTU domain, ubiquitin aldehyde binding 1 0.527
CCNB1 cyclin B1 0.515
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.515
HDAC1 histone deacetylase 1 0.515
XIAP X-linked inhibitor of apoptosis 0.514
RAD23A RAD23 homolog A (S. cerevisiae) 0.512
CCND1 cyclin D1 0.512
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.499
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.499
TADA3 transcriptional adaptor 3 0.464
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.463
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.455
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 0.449
DVL1 dishevelled, dsh homolog 1 (Drosophila) 0.446
CCNA2 cyclin A2 0.443
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.443
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) 0.408
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 0.405
BRAF v-raf murine sarcoma viral oncogene homolog B1 0.398
SIAH1 seven in absentia homolog 1 (Drosophila) 0.395
DVL2 dishevelled, dsh homolog 2 (Drosophila) 0.394
ADRM1 adhesion regulating molecule 1 0.393
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.386
CDC23 cell division cycle 23 homolog (S. cerevisiae) 0.380
BTRC beta-transducin repeat containing 0.380
UBE2D1 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) 0.366
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.360
BCL2L1 BCL2-like 1 0.358
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.350
RBL1 retinoblastoma-like 1 (p107) 0.350
POMP proteasome maturation protein 0.338
ARIH2 ariadne homolog 2 (Drosophila) 0.320
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.312
ZNF263 zinc finger protein 263 0.305
GFI1B growth factor independent 1B transcription repressor 0.303
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.302
UBE2N ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) 0.302
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.301
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Ctnnb1 catenin (cadherin associated protein), beta 1 1.000
Trp53 transformation related protein 53 0.998
Gsk3b glycogen synthase kinase 3 beta 0.984
Pten phosphatase and tensin homolog 0.967
Per2 period homolog 2 (Drosophila) 0.935
Axin1 axin 1 0.920
Per1 period homolog 1 (Drosophila) 0.856
Mdm2 transformed mouse 3T3 cell double minute 2 0.829
Ncoa3 nuclear receptor coactivator 3 0.764
Apc adenomatosis polyposis coli 0.741
Psen1 presenilin 1 0.727
Lrp6 low density lipoprotein receptor-related protein 6 0.630
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.608
Ccnf cyclin F 0.485
Psmb7 proteasome (prosome, macropain) subunit, beta type 7 0.469
Dctn1 dynactin 1 0.446
Ccnb1 cyclin B1 0.406
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.395
Hif1a hypoxia inducible factor 1, alpha subunit 0.378
Sap18 Sin3-associated polypeptide 18 0.345
Grb2 growth factor receptor bound protein 2 0.331
Cry2 cryptochrome 2 (photolyase-like) 0.326
Gclm glutamate-cysteine ligase, modifier subunit 0.319
Ube2n ubiquitin-conjugating enzyme E2N 0.317
Pcna proliferating cell nuclear antigen 0.315
Clock circadian locomotor output cycles kaput 0.311
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.303
Psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.297
Atf4 activating transcription factor 4 0.295
Mdm4 transformed mouse 3T3 cell double minute 4 0.291
Notch2 Notch gene homolog 2 (Drosophila) 0.287
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.281
Taf9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor 0.274
Brca1 breast cancer 1 0.272
Prkce protein kinase C, epsilon 0.271
Grb10 growth factor receptor bound protein 10 0.271
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.269
Pax8 paired box gene 8 0.268
Tceb1 transcription elongation factor B (SIII), polypeptide 1 0.255
Smad7 MAD homolog 7 (Drosophila) 0.252
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.248
Aamp angio-associated migratory protein 0.244
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.233
Hprt hypoxanthine guanine phosphoribosyl transferase 0.232
Vdac3 voltage-dependent anion channel 3 0.230
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.229
Cdk1 cyclin-dependent kinase 1 0.227
Mlf2 myeloid leukemia factor 2 0.223
Bcl2 B-cell leukemia/lymphoma 2 0.222
Fgfr1 fibroblast growth factor receptor 1 0.220
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.217
Cops2 COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana) 0.208
Htt huntingtin 0.205
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.203
Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 0.200
Vhl von Hippel-Lindau tumor suppressor 0.200
Foxm1 forkhead box M1 0.196
Cdk2 cyclin-dependent kinase 2 0.192
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.191
Ccna2 cyclin A2 0.190
App amyloid beta (A4) precursor protein 0.182
Akt1 thymoma viral proto-oncogene 1 0.177
Smurf2 SMAD specific E3 ubiquitin protein ligase 2 0.172
Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform 0.171
Sufu suppressor of fused homolog (Drosophila) 0.169
Tomm70a translocase of outer mitochondrial membrane 70 homolog A (yeast) 0.169
T brachyury 0.169
Rnf19a ring finger protein 19A 0.168
Cyld cylindromatosis (turban tumor syndrome) 0.166
Glrx3 glutaredoxin 3 0.160
Usp15 ubiquitin specific peptidase 15 0.160
Ptov1 prostate tumor over expressed gene 1 0.159
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.155
Vps72 vacuolar protein sorting 72 (yeast) 0.151
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.151
Setdb1 SET domain, bifurcated 1 0.147
Ccnb2 cyclin B2 0.147
Ncstn nicastrin 0.145
Rnf111 ring finger 111 0.142
Anapc2 anaphase promoting complex subunit 2 0.142
Ppp1ca protein phosphatase 1, catalytic subunit, alpha isoform 0.141
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.141
Ubxn1 UBX domain protein 1 0.140
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.139
Rnf11 ring finger protein 11 0.139
Ooep oocyte expressed protein homolog (dog) 0.137
Kiss1 KiSS-1 metastasis-suppressor 0.136
Vangl2 vang-like 2 (van gogh, Drosophila) 0.135
Ran RAN, member RAS oncogene family 0.135
Smad2 MAD homolog 2 (Drosophila) 0.135
Csnk1g2 casein kinase 1, gamma 2 0.131
Ilk integrin linked kinase 0.131
Sgol2 shugoshin-like 2 (S. pombe) 0.127
Wnt3a wingless-related MMTV integration site 3A 0.125
Ptch1 patched homolog 1 0.124
Cops6 COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana) 0.123
Lef1 lymphoid enhancer binding factor 1 0.121
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.121
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.120
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.120
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Rattus norvegicus
Name Description Probability Func Analog Organism
Eef2 eukaryotic translation elongation factor 2 0.039
Cops7a COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) 0.020
Use1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 0.012
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform 0.012
Syngr2 synaptogyrin 2 0.011
Ppm1a protein phosphatase 1A, magnesium dependent, alpha isoform 0.010