The network for 'regulation of localization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of localization

Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
HSP82 Hsp82p 0.915
BMH2 Bmh2p 0.833
RVS167 Rvs167p 0.743
ROM2 Rom2p 0.738
DAM1 Dam1p 0.734
CLA4 Cla4p 0.687
SLT2 Slt2p 0.654
ASK1 Ask1p 0.578
MYO5 Myo5p 0.569
DIA2 Dia2p 0.560
SEC7 Sec7p 0.551
KAP123 Kap123p 0.547
VPS33 Vps33p 0.488
STE11 Ste11p 0.471
AKL1 Akl1p 0.467
MSG5 Msg5p 0.459
RPN4 Rpn4p 0.453
CDC14 Cdc14p 0.446
VPS27 Vps27p 0.440
PEP3 Pep3p 0.420
IKI3 Iki3p 0.406
DUO1 Duo1p 0.404
PBS2 Pbs2p 0.386
CDC28 Cdc28p 0.386
VPS1 Vps1p 0.372
YPK1 Ypk1p 0.372
RTS1 Rts1p 0.371
ROD1 Rod1p 0.366
APL2 Apl2p 0.358
VPS54 Vps54p 0.353
GLC7 Glc7p 0.343
DBF2 Dbf2p 0.322
SSK2 Ssk2p 0.320
INP52 Inp52p 0.318
YKT6 Ykt6p 0.307
VHS1 Vhs1p 0.303
MSN2 Msn2p 0.292
CMP2 Cmp2p 0.282
HOG1 Hog1p 0.272
PEP5 Pep5p 0.268
KXD1 Kxd1p 0.265
CBK1 Cbk1p 0.264
KDX1 Kdx1p 0.259
RIM21 Rim21p 0.246
SIC1 Sic1p 0.246
PSK1 Psk1p 0.246
DAD4 Dad4p 0.245
MOB1 Mob1p 0.240
ACC1 Acc1p 0.239
SPC34 Spc34p 0.234
VPS21 Vps21p 0.231
GRR1 Grr1p 0.229
BRO1 Bro1p 0.229
NPR1 Npr1p 0.223
LSM1 Lsm1p 0.219
APL3 Apl3p 0.217
STE4 Ste4p 0.215
UBP15 Ubp15p 0.208
VAC8 Vac8p 0.198
TAT1 Tat1p 0.194
GPR1 Gpr1p 0.194
YME1 Yme1p 0.188
FUS3 Fus3p 0.188
RLM1 Rlm1p 0.185
TOR1 Tor1p 0.178
AQY2 Aqy2p 0.175
MIG1 Mig1p 0.172
SRP54 Srp54p 0.172
SNC2 Snc2p 0.171
APS2 Aps2p 0.169
SPC19 Spc19p 0.168
MGA2 Mga2p 0.167
RTG3 Rtg3p 0.167
BLS1 Bls1p 0.165
VPS71 Vps71p 0.163
POG1 Pog1p 0.160
PHO85 Pho85p 0.159
ARC15 Arc15p 0.157
DAD1 Dad1p 0.156
CMD1 Cmd1p 0.152
TRA1 Tra1p 0.150
SNF7 Snf7p 0.150
EAF1 Eaf1p 0.149
ECM22 Ecm22p 0.147
BNI1 Bni1p 0.147
VAM7 Vam7p 0.144
MOB2 Mob2p 0.144
SIP2 Sip2p 0.142
RPA135 Rpa135p 0.142
PTK2 Ptk2p 0.140
SWI5 Swi5p 0.139
FAR11 Far11p 0.139
PRK1 Prk1p 0.137
YPT6 Ypt6p 0.136
GYL1 Gyl1p 0.135
VAB2 Vab2p 0.135
SEC4 Sec4p 0.134
YAK1 Yak1p 0.133
HUT1 Hut1p 0.131
RIM8 Rim8p 0.131
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
vab-3 Protein VAB-3 0.530
pkg-1 Protein PKG-1 0.479
mig-5 Protein MIG-5 0.474
unc-62 Protein UNC-62 0.451
unc-43 Protein UNC-43 0.439
plc-1 Protein PLC-1 0.418
egl-18 Protein EGL-18 0.413
inx-13 Protein INX-13 0.389
unc-9 Protein UNC-9 0.386
tag-232 Protein TAG-232 0.384
spc-1 Protein SPC-1 0.377
alx-1 Protein ALX-1 0.350
egl-44 Protein EGL-44 0.324
unc-40 Protein UNC-40 0.285
inx-15 Protein INX-15 0.285
hlh-2 Protein HLH-2 0.283
rig-6 Protein RIG-6 0.278
nlg-1 Protein NLG-1 0.275
vha-8 Protein VHA-8 0.272
hsr-9 Protein HSR-9 0.272
vav-1 Protein VAV-1 0.270
cam-1 Protein CAM-1 0.270
ttr-6 Protein TTR-6 0.268
egl-5 Protein EGL-5 0.268
imb-2 Protein IMB-2 0.259
ubxn-2 Protein UBXN-2 0.257
CELE_C18C4.5 Protein C18C4.5 0.253
lin-45 Protein LIN-45 0.249
akt-1 Protein AKT-1 0.246
unc-26 Protein UNC-26 0.242
rgs-2 Protein RGS-2 0.242
lat-1 Protein LAT-1 0.242
acs-4 Protein ACS-4 0.236
eat-6 Protein EAT-6 0.236
pxf-1 Protein PXF-1 0.231
egl-27 Protein EGL-27 0.230
C32D5.3 Protein C32D5.3 0.222
CELE_M117.1 Protein M117.1 0.220
npp-7 Protein NPP-7 0.220
egg-6 Protein EGG-6 0.219
unc-7 Protein UNC-7 0.218
mdt-1.2 Protein MDT-1.2 0.213
mex-3 Protein MEX-3 0.212
hlh-1 Protein HLH-1 0.203
bar-1 Protein BAR-1 0.198
CELE_C39E9.11 Protein C39E9.11 0.197
CELE_Y64G10A.6 Protein Y64G10A.6 0.197
unc-32 Protein UNC-32 0.191
unc-42 Protein UNC-42 0.191
sax-3 Protein SAX-3 0.191
ptr-14 Protein PTR-14 0.190
sma-6 Protein SMA-6 0.189
dpy-26 Protein DPY-26 0.189
pry-1 Protein PRY-1 0.184
efn-2 Protein EFN-2 0.183
ttr-2 Protein TTR-2 0.181
lst-1 Protein LST-1 0.181
aha-1 Protein AHA-1 0.179
egl-15 Protein EGL-15 0.176
mig-2 Protein MIG-2 0.176
pdfr-1 Protein PDFR-1 0.174
eor-1 Protein EOR-1 0.174
hum-5 Protein HUM-5 0.170
hmg-5 Protein HMG-5 0.170
daf-3 Protein DAF-3 0.169
syg-1 Protein SYG-1 0.169
rsbp-1 Protein RSBP-1 0.169
sams-3 Protein SAMS-3 0.165
T14G10.5 Protein T14G10.5 0.164
rab-5 Protein RAB-5 0.163
cmd-1 Protein CMD-1 0.163
wwp-1 Protein WWP-1 0.163
madf-5 Protein MADF-5 0.162
pak-1 Protein PAK-1 0.161
egl-13 Protein EGL-13 0.159
mek-2 Protein MEK-2 0.158
bag-1 Protein BAG-1 0.158
unc-38 Protein UNC-38 0.157
dgk-2 Protein DGK-2 0.157
lin-17 Protein LIN-17 0.157
CELE_T10C6.5 Protein T10C6.5 0.157
R10E12.2 Protein R10E12.2 0.157
mex-1 Protein MEX-1 0.154
tbc-9 Protein TBC-9 0.154
dyc-1 Protein DYC-1 0.154
pfn-2 Protein PFN-2 0.153
T26C12.1 Protein T26C12.1 0.153
dnj-5 Protein DNJ-5 0.153
zfp-1 Protein ZFP-1 0.153
unc-115 Protein UNC-115 0.151
nap-1 Protein NAP-1 0.151
dgk-4 Protein DGK-4 0.151
nab-1 Protein NAB-1 0.150
elt-6 Protein ELT-6 0.147
twk-18 Protein TWK-18 0.147
irx-1 Protein IRX-1 0.146
T05G5.1 Protein T05G5.1 0.145
ifg-1 Protein IFG-1 0.143
glo-4 Protein GLO-4 0.142
hsp-3 Protein HSP-3 0.142
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Danio rerio
Name Description Probability Func Analog Organism
shha sonic hedgehog a 0.954
cdh2 cadherin 2, neuronal 0.662
jag2 jagged 2 0.622
tal1 T-cell acute lymphocytic leukemia 1 0.537
ptch1 patched 1 0.536
ndr2 nodal-related 2 0.521
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.516
gata6 GATA-binding protein 6 0.504
bmp4 bone morphogenetic protein 4 0.495
sox9b SRY-box containing gene 9b 0.495
otx5 orthodenticle homolog 5 0.492
notch1a notch homolog 1a 0.492
podxl podocalyxin-like 0.466
fgf3 fibroblast growth factor 3 0.464
trim33 tripartite motif-containing 33 0.458
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.456
itgb1b integrin, beta 1b 0.436
slit3 slit (Drosophila) homolog 3 0.427
slc1a2b solute carrier family 1 (glial high affinity glutamate transporter), member 2b 0.417
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.400
nanos3 nanos homolog 3 0.394
fzd7a frizzled homolog 7a 0.390
plcg1 phospholipase C, gamma 1 0.371
gnrh3 gonadotropin-releasing hormone 3 0.369
wnt5b wingless-type MMTV integration site family, member 5b 0.369
valopa vertebrate ancient long opsin a 0.366
osr2 odd-skipped related 2 (Drosophila) 0.365
pvrl1b poliovirus receptor-related 1b 0.364
cxcr4b chemokine (C-X-C motif), receptor 4b 0.360
flh floating head 0.351
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.349
osr1 odd-skipped related 1 (Drosophila) 0.341
cdh5 cadherin 5 0.332
cldnb claudin b 0.331
esrra estrogen-related receptor alpha 0.328
wnt4a wingless-type MMTV integration site family, member 4a 0.316
sh3gl1b SH3-domain GRB2-like 1b 0.292
mmp14a matrix metalloproteinase 14a (membrane-inserted) 0.291
hpca hippocalcin 0.287
opn1sw2 opsin 1 (cone pigments), short-wave-sensitive 2 0.283
fabp2 fatty acid binding protein 2, intestinal 0.281
tll1 tolloid-like 1 0.280
cnn2 calponin 2 0.276
si:dkeyp-51c11.1 si:dkeyp-51c11.1 0.274
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.273
atp1a1a.4 ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide 0.273
lama2 laminin, alpha 2 0.271
sox32 SRY-box containing gene 32 0.267
notch1b notch homolog 1b 0.267
khdrbs1a KH domain containing, RNA binding, signal transduction associated 1a 0.263
ptpra protein tyrosine phosphatase, receptor type, A 0.261
dlb deltaB 0.259
rx3 retinal homeobox gene 3 0.254
hnf1ba HNF1 homeobox Ba 0.247
met met proto-oncogene (hepatocyte growth factor receptor) 0.246
kdrl kinase insert domain receptor like 0.245
gata5 GATA-binding protein 5 0.245
gata3 GATA-binding protein 3 0.238
slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.238
crabp2a cellular retinoic acid binding protein 2, a 0.236
esrrga estrogen-related receptor gamma a 0.230
bmp2a bone morphogenetic protein 2a 0.224
ins preproinsulin 0.223
jag1b jagged 1b 0.222
pdlim1 PDZ and LIM domain 1 (elfin) 0.221
foxh1 forkhead box H1 0.219
opn4l opsin 4, like 0.218
her1 hairy-related 1 0.217
ptgs2a prostaglandin-endoperoxide synthase 2a 0.216
tmem59l transmembrane protein 59-like and transmembrane protein 59-like 0.213
smad5 MAD homolog 5 (Drosophila) 0.213
cacnb4a calcium channel, voltage-dependent, beta 4a subunit 0.212
cmyb transcription factor cmyb 0.211
dazl daz-like gene 0.209
hcrt hypocretin (orexin) neuropeptide precursor 0.207
inha inhibin, alpha 0.204
xirp2a xin actin-binding repeat containing 2a 0.202
tbx1 T-box 1 0.202
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.199
adcyap1a adenylate cyclase activating polypeptide 1a 0.197
cdh1 cadherin 1, epithelial 0.196
sox4a SRY-box containing gene 4a 0.196
flncb filamin C, gamma b (actin binding protein 280) 0.195
gc3 guanylyl cyclase 3 0.195
mapk1 mitogen-activated protein kinase 1 0.192
mc4r melanocortin 4 receptor 0.192
cadm2a cell adhesion molecule 2a 0.191
rtn1a reticulon 1a 0.187
ncam1b neural cell adhesion molecule 1b 0.186
copg2 coatomer protein complex, subunit gamma 2 0.184
dla deltaA 0.180
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.179
gpr126 G protein-coupled receptor 126 0.179
hhip hedgehog interacting protein 0.178
pvrl1a poliovirus receptor-related 1a 0.177
fgf17 fibroblast growth factor 17 0.177
sim1a single-minded homolog 1a (Drosophila) 0.176
mapk12 mitogen-activated protein kinase 12 0.175
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.174
ryr2a ryanodine receptor 2a (cardiac) 0.174
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Rac1 CG2248 gene product from transcript CG2248-RA 0.986
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.982
Syx1A Syntaxin 1A 0.982
EcR Ecdysone receptor 0.969
Khc Kinesin heavy chain 0.968
cpb capping protein beta 0.942
sax saxophone 0.933
ovo CG6824 gene product from transcript CG6824-RE 0.931
Fmr1 CG6203 gene product from transcript CG6203-RC 0.926
fz2 frizzled 2 0.896
osk oskar 0.889
Fas2 Fasciclin 2 0.882
bsk basket 0.875
shot short stop 0.866
shi shibire 0.856
Smox Smad on X 0.854
CaMKII Calcium/calmodulin-dependent protein kinase II 0.853
mbc myoblast city 0.853
RhoGEF2 CG9635 gene product from transcript CG9635-RF 0.844
egh egghead 0.832
stai stathmin 0.831
Cdc42 CG12530 gene product from transcript CG12530-RA 0.829
puc puckered 0.828
Abl Abl tyrosine kinase 0.825
Lam Lamin 0.823
robo roundabout 0.813
dco discs overgrown 0.795
Rab5 Rab-protein 5 0.791
spas spastin 0.790
Pp1-87B Protein phosphatase 1 at 87B 0.785
milt milton 0.783
Sema-1a CG18405 gene product from transcript CG18405-RD 0.783
egl egalitarian 0.780
G-oalpha47A G protein oalpha 47A 0.779
ninaE neither inactivation nor afterpotential E 0.777
wls wntless 0.773
Akt1 CG4006 gene product from transcript CG4006-RA 0.772
GluRIIA Glutamate receptor IIA 0.772
Egfr Epidermal growth factor receptor 0.752
shn schnurri 0.735
aux auxillin 0.731
eff effete 0.721
SoxN SoxNeuro 0.720
gcm glial cells missing 0.698
fog folded gastrulation 0.693
Pak PAK-kinase 0.691
chb chromosome bows 0.690
Ca-P60A Calcium ATPase at 60A 0.678
pum pumilio 0.664
par-1 CG8201 gene product from transcript CG8201-RA 0.661
Tsc1 CG6147 gene product from transcript CG6147-RA 0.655
chic chickadee 0.654
Pka-C1 cAMP-dependent protein kinase 1 0.653
alpha-Adaptin CG4260 gene product from transcript CG4260-RA 0.652
Rab11 Rab-protein 11 0.639
Dscam Down syndrome cell adhesion molecule 0.637
Mad Mothers against dpp 0.635
CdsA CDP diglyceride synthetase 0.632
Gp150 CG5820 gene product from transcript CG5820-RA 0.630
Dad Daughters against dpp 0.630
cup CG11181 gene product from transcript CG11181-RB 0.617
ap apterous 0.612
Src42A Src oncogene at 42A 0.597
Alk CG8250 gene product from transcript CG8250-RA 0.595
Ptp69D Protein tyrosine phosphatase 69D 0.594
wg wingless 0.587
Tao-1 CG14217 gene product from transcript CG14217-RF 0.580
trbl tribbles 0.578
wit wishful thinking 0.576
per period 0.566
msps mini spindles 0.563
Pp2B-14D Protein phosphatase 2B at 14D 0.560
tum tumbleweed 0.555
14-3-3zeta CG17870 gene product from transcript CG17870-RB 0.553
trio CG18214 gene product from transcript CG18214-RA 0.549
hts hu li tai shao 0.548
InR Insulin-like receptor 0.546
dnc dunce 0.542
tkv thickveins 0.533
Jra Jun-related antigen 0.528
Gyc76C Guanylyl cyclase at 76C 0.526
hyd hyperplastic discs 0.523
rut rutabaga 0.522
kay kayak 0.516
pho pleiohomeotic 0.504
dos daughter of sevenless 0.500
Rab7 Rab-protein 7 0.497
pros prospero 0.496
unc-13 CG2999 gene product from transcript CG2999-RA 0.495
ago archipelago 0.495
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.489
me31B maternal expression at 31B 0.488
tutl turtle 0.487
drk downstream of receptor kinase 0.487
stck steamer duck 0.486
TSG101 tumor suppressor protein 101 0.486
endoA endophilin A 0.484
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.484
Nacalpha Nascent polypeptide associated complex protein alpha subunit 0.477
Mhc Myosin heavy chain 0.476
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism