Homo sapiens

267 known processes

ENG

endoglin

(Aliases: FLJ41744,END,CD105,ORW,ORW1,HHT1)

ENG biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of odontogenesis GO:0042482 3 1.000
positive regulation of cardioblast differentiation GO:0051891 2 1.000
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 22 1.000
negative regulation of trophoblast cell migration GO:1901164 3 1.000
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.999
positive regulation of hair follicle maturation GO:0048818 2 0.998
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.998
endocardial cushion development GO:0003197 3 0.996
Mouse
cell matrix adhesion involved in ameboidal cell migration GO:0003366 2 0.996
negative regulation of epithelial cell migration GO:0010633 38 0.996
negative regulation of low density lipoprotein particle receptor biosynthetic process GO:0045715 3 0.995
atrial septum primum morphogenesis GO:0003289 1 0.994
regulation of odontogenesis GO:0042481 4 0.994
negative regulation of macrophage cytokine production GO:0010936 3 0.989
cell matrix adhesion GO:0007160 85 0.989
positive regulation of fibroblast migration GO:0010763 3 0.988
angiogenesis GO:0001525 147 0.988
Mouse
sensory perception of smell GO:0007608 2 0.987
positive regulation of cellular amine metabolic process GO:0033240 7 0.986
regulation of lipoprotein metabolic process GO:0050746 7 0.986
negative regulation of chondrocyte proliferation GO:1902731 1 0.983
response to transforming growth factor beta GO:0071559 94 0.979
blood vessel endothelial cell migration GO:0043534 42 0.979
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.978
regulation of locomotion GO:0040012 329 0.977
vasculature development GO:0001944 181 0.975
kidney development GO:0001822 53 0.974
negative regulation of cell motility GO:2000146 104 0.973
regulation of smad protein import into nucleus GO:0060390 10 0.971
regulation of cellular amine metabolic process GO:0033238 11 0.970
regulation of cell migration GO:0030334 289 0.969
cardiac muscle cell fate commitment GO:0060923 4 0.964
blood vessel development GO:0001568 172 0.963
negative regulation of chorionic trophoblast cell proliferation GO:1901383 2 0.963
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 2 0.962
atrial septum morphogenesis GO:0060413 5 0.961
ectoderm development GO:0007398 3 0.960
positive regulation of phagocytosis engulfment GO:0060100 1 0.960
epithelium migration GO:0090132 119 0.956
glial cell migration GO:0008347 4 0.954
lens development in camera type eye GO:0002088 2 0.948
positive regulation of trophoblast cell migration GO:1901165 2 0.948
chondrocyte development GO:0002063 1 0.946
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.943
regulation of epithelial cell migration GO:0010632 93 0.942
positive regulation of protein kinase activity GO:0045860 190 0.942
fibroblast migration GO:0010761 7 0.940
regulation of mesonephros development GO:0061217 3 0.938
regulation of catagen GO:0051794 3 0.937
mapk cascade GO:0000165 288 0.933
regulation of cellular response to growth factor stimulus GO:0090287 76 0.931
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.926
salivary gland morphogenesis GO:0007435 4 0.925
biological adhesion GO:0022610 331 0.925
positive regulation of isotype switching to iga isotypes GO:0048298 2 0.924
cellular amine metabolic process GO:0044106 41 0.923
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.923
circulatory system development GO:0072359 262 0.922
urogenital system development GO:0001655 65 0.920
ameboidal type cell migration GO:0001667 135 0.915
tissue migration GO:0090130 119 0.915
positive regulation of cell motility GO:2000147 177 0.913
anatomical structure formation involved in morphogenesis GO:0048646 284 0.910
Mouse
blood vessel morphogenesis GO:0048514 162 0.906
cardiac epithelial to mesenchymal transition GO:0060317 3 0.906
Human
endothelial cell migration GO:0043542 86 0.906
positive regulation of endothelial cell migration GO:0010595 39 0.905
cardiovascular system development GO:0072358 262 0.904
negative regulation of cell proliferation GO:0008285 228 0.903
regulation of cell motility GO:2000145 299 0.903
positive regulation of mapk cascade GO:0043410 190 0.902
negative regulation of alkaline phosphatase activity GO:0010693 2 0.898
single organismal cell cell adhesion GO:0016337 148 0.893
positive regulation of biomineral tissue development GO:0070169 20 0.892
movement in host environment GO:0052126 25 0.889
cellular ketone metabolic process GO:0042180 80 0.888
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.887
positive regulation of mesonephros development GO:0061213 2 0.885
positive regulation of developmental process GO:0051094 314 0.882
Mouse
regulation of cellular amino acid metabolic process GO:0006521 6 0.880
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.880
mitral valve morphogenesis GO:0003183 2 0.879
entry into host GO:0044409 25 0.878
positive regulation of cell differentiation GO:0045597 211 0.878
endoderm development GO:0007492 33 0.875
positive regulation of cell proliferation GO:0008284 301 0.874
regulation of determination of dorsal identity GO:2000015 2 0.872
circulatory system process GO:0003013 113 0.871
cell migration involved in sprouting angiogenesis GO:0002042 19 0.865
endocardial cushion cell differentiation GO:0061443 1 0.861
viral process GO:0016032 146 0.859
patterning of blood vessels GO:0001569 2 0.859
Mouse
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.855
renal system development GO:0072001 63 0.851
entry into other organism involved in symbiotic interaction GO:0051828 25 0.850
amine metabolic process GO:0009308 44 0.849
positive regulation of locomotion GO:0040017 186 0.849
peptidyl tyrosine phosphorylation GO:0018108 170 0.844
segmentation GO:0035282 4 0.838
sprouting angiogenesis GO:0002040 29 0.838
mitral valve development GO:0003174 3 0.837
cellular extravasation GO:0045123 21 0.835
lens morphogenesis in camera type eye GO:0002089 2 0.835
regulation of chemotaxis GO:0050920 74 0.833
cell adhesion GO:0007155 325 0.832
nephron development GO:0072006 30 0.825
odontogenesis GO:0042476 25 0.820
interaction with host GO:0051701 42 0.820
regulation of vasculature development GO:1901342 97 0.819
Mouse
positive regulation of bone mineralization GO:0030501 19 0.817
positive regulation of phosphorylation GO:0042327 394 0.815
regulation of cellular ketone metabolic process GO:0010565 50 0.815
regulation of bone mineralization GO:0030500 29 0.813
angiogenesis involved in wound healing GO:0060055 4 0.813
regulation of biomineral tissue development GO:0070167 31 0.810
regulation of cell adhesion GO:0030155 166 0.806
regulation of entry of bacterium into host cell GO:2000535 2 0.804
cell junction organization GO:0034330 79 0.799
secretion GO:0046903 254 0.797
regulation of blood pressure GO:0008217 30 0.796
cellular amino acid metabolic process GO:0006520 116 0.793
regulation of pathway restricted smad protein phosphorylation GO:0060393 34 0.790
negative regulation of calcium ion transport into cytosol GO:0010523 3 0.787
regulation of fibroblast migration GO:0010762 7 0.784
epithelial cell migration GO:0010631 119 0.784
cell junction assembly GO:0034329 67 0.782
mesenchymal cell development GO:0014031 50 0.781
Human
positive regulation of epithelial cell migration GO:0010634 55 0.778
response to growth factor GO:0070848 205 0.777
receptor metabolic process GO:0043112 81 0.774
morphogenesis of a branching structure GO:0001763 21 0.771
Mouse
digestive system development GO:0055123 75 0.770
negative regulation of locomotion GO:0040013 118 0.763
positive regulation of chemotaxis GO:0050921 57 0.758
negative regulation of endothelial cell migration GO:0010596 29 0.757
foam cell differentiation GO:0090077 15 0.756
multi organism cellular process GO:0044764 156 0.752
response to prostaglandin e GO:0034695 6 0.752
Human
negative regulation of cell substrate adhesion GO:0010812 24 0.749
positive regulation of cell migration GO:0030335 172 0.748
sensory perception of chemical stimulus GO:0007606 38 0.745
transmembrane transport GO:0055085 399 0.742
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.739
regulation of multicellular organismal metabolic process GO:0044246 17 0.739
embryonic morphogenesis GO:0048598 85 0.737
Mouse
single organism cell adhesion GO:0098602 179 0.733
cardiac atrium morphogenesis GO:0003209 7 0.731
leukocyte migration GO:0050900 107 0.721
cellular response to growth factor stimulus GO:0071363 197 0.719
chorionic trophoblast cell proliferation GO:0097360 2 0.718
wound healing GO:0042060 115 0.717
negative regulation of blood pressure GO:0045776 3 0.709
regulation of blood vessel endothelial cell migration GO:0043535 30 0.708
regulation of chorionic trophoblast cell proliferation GO:1901382 2 0.703
peptidyl threonine modification GO:0018210 45 0.703
cell chemotaxis GO:0060326 112 0.701
peptidyl serine phosphorylation GO:0018105 101 0.701
endocardial cell fate commitment GO:0060957 1 0.699
positive regulation of map kinase activity GO:0043406 80 0.698
positive regulation of protein phosphorylation GO:0001934 313 0.697
response to hypoxia GO:0001666 96 0.695
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.692
negative regulation of skeletal muscle tissue development GO:0048642 2 0.689
regulation of lung blood pressure GO:0014916 1 0.684
interspecies interaction between organisms GO:0044419 156 0.682
response to wounding GO:0009611 168 0.682
negative regulation of multicellular organismal process GO:0051241 317 0.681
positive regulation of cell adhesion GO:0045785 84 0.678
negative regulation of blood vessel endothelial cell migration GO:0043537 16 0.677
chondrocyte differentiation GO:0002062 17 0.672
purine ribonucleotide biosynthetic process GO:0009152 79 0.672
response to lipid GO:0033993 206 0.665
Human
cellular response to glucocorticoid stimulus GO:0071385 4 0.664
positive regulation of cellular component organization GO:0051130 376 0.662
regulation of hair follicle maturation GO:0048819 3 0.661
regulation of protein localization GO:0032880 296 0.661
cell substrate adherens junction assembly GO:0007045 30 0.660
epithelial cell differentiation GO:0030855 141 0.657
negative regulation of cell adhesion GO:0007162 64 0.653
multicellular organismal macromolecule metabolic process GO:0044259 29 0.650
metal ion transport GO:0030001 272 0.648
cardiac muscle tissue development GO:0048738 39 0.644
morphogenesis of an epithelial sheet GO:0002011 12 0.644
regulation of cellular component movement GO:0051270 334 0.643
memory GO:0007613 3 0.639
extrinsic apoptotic signaling pathway GO:0097191 119 0.637
response to fatty acid GO:0070542 13 0.637
Human
osteoblast differentiation GO:0001649 92 0.635
adherens junction assembly GO:0034333 34 0.633
regulation of cell matrix adhesion GO:0001952 42 0.631
regulation of cardioblast differentiation GO:0051890 4 0.630
negative regulation of apoptotic signaling pathway GO:2001234 97 0.627
negative regulation of cell differentiation GO:0045596 171 0.627
divalent metal ion transport GO:0070838 152 0.619
negative regulation of cell migration GO:0030336 102 0.617
septum primum development GO:0003284 1 0.616
organ morphogenesis GO:0009887 147 0.613
Human Mouse
regulation of anatomical structure morphogenesis GO:0022603 286 0.606
Mouse
endothelial cell fate commitment GO:0060839 3 0.605
regulation of systemic arterial blood pressure GO:0003073 19 0.605
catagen GO:0042637 3 0.596
chondrocyte proliferation GO:0035988 4 0.594
cell substrate adhesion GO:0031589 132 0.592
biomineral tissue development GO:0031214 39 0.592
dephosphorylation GO:0016311 209 0.590
negative regulation of apoptotic process GO:0043066 316 0.588
negative regulation of lipid transport GO:0032369 18 0.586
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.585
viral entry into host cell GO:0046718 24 0.584
positive regulation of cellular component movement GO:0051272 181 0.582
regulation of focal adhesion assembly GO:0051893 20 0.581
apoptotic signaling pathway GO:0097190 268 0.576
positive regulation of hydrolase activity GO:0051345 331 0.574
cation transport GO:0006812 331 0.573
cardiocyte differentiation GO:0035051 23 0.568
positive regulation of apoptotic process GO:0043065 246 0.566
regulation of binding GO:0051098 111 0.564
enzyme linked receptor protein signaling pathway GO:0007167 303 0.564
ossification GO:0001503 121 0.564
determination of dorsal identity GO:0048263 4 0.563
positive regulation of angiogenesis GO:0045766 51 0.559
Mouse
cellular component morphogenesis GO:0032989 314 0.558
Human
taxis GO:0042330 157 0.555
formation of primary germ layer GO:0001704 42 0.554
endocardial cushion cell fate commitment GO:0061445 1 0.550
regulation of cellular component biogenesis GO:0044087 281 0.549
cell activation GO:0001775 213 0.549
response to vitamin d GO:0033280 10 0.548
response to cholesterol GO:0070723 11 0.547
interleukin 17 production GO:0032620 12 0.547
cardiac atrium development GO:0003230 10 0.539
immune response GO:0006955 307 0.538
Human
epiboly GO:0090504 9 0.534
calcium ion transport GO:0006816 147 0.534
peptidyl threonine phosphorylation GO:0018107 41 0.532
macrophage cytokine production GO:0010934 4 0.531
positive regulation of protein kinase b signaling GO:0051897 42 0.530
epiboly involved in wound healing GO:0090505 8 0.527
positive regulation of behavior GO:0048520 60 0.526
response to oxygen levels GO:0070482 100 0.524
negative regulation of phagocytosis GO:0050765 4 0.524
regulation of osteoblast differentiation GO:0045667 38 0.523
wound healing spreading of epidermal cells GO:0035313 6 0.521
renal tubule development GO:0061326 19 0.521
adrenal gland development GO:0030325 7 0.518
bone mineralization GO:0030282 34 0.517
vesicle mediated transport GO:0016192 371 0.516
muscle cell proliferation GO:0033002 35 0.514
cell adhesion mediated by integrin GO:0033627 27 0.513
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.511
regulation of establishment of protein localization GO:0070201 242 0.510
digestive tract development GO:0048565 75 0.509
regulation of interleukin 17 production GO:0032660 12 0.509
movement in environment of other organism involved in symbiotic interaction GO:0052192 25 0.505
chemotaxis GO:0006935 157 0.504
transforming growth factor beta production GO:0071604 14 0.503
regulation of bmp signaling pathway GO:0030510 27 0.501
negative regulation of cell death GO:0060548 345 0.499
regulation of ossification GO:0030278 58 0.497
regulation of cell cell adhesion GO:0022407 57 0.494
muscle organ development GO:0007517 56 0.492
regulation of endothelial cell migration GO:0010594 67 0.492
positive regulation of hair follicle development GO:0051798 3 0.492
activation of mapk activity GO:0000187 45 0.490
regulation of apoptotic signaling pathway GO:2001233 175 0.484
peptidyl tyrosine modification GO:0018212 170 0.482
plasma membrane organization GO:0007009 115 0.479
embryonic viscerocranium morphogenesis GO:0048703 1 0.474
neurological system process GO:0050877 163 0.474
single organism cellular localization GO:1902580 332 0.472
protein kinase b signaling GO:0043491 69 0.470
negative regulation of entry of bacterium into host cell GO:2000536 1 0.469
cellular response to endogenous stimulus GO:0071495 336 0.467
endothelial cell proliferation GO:0001935 65 0.466
cartilage development involved in endochondral bone morphogenesis GO:0060351 2 0.462
reactive oxygen species metabolic process GO:0072593 75 0.462
positive regulation of axon extension GO:0045773 4 0.459
focal adhesion assembly GO:0048041 30 0.457
atrioventricular valve morphogenesis GO:0003181 2 0.456
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.456
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.451
eye development GO:0001654 42 0.450
digestive tract morphogenesis GO:0048546 56 0.449
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 4 0.442
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.441
adherens junction organization GO:0034332 36 0.440
positive regulation of programmed cell death GO:0043068 249 0.439
regulation of cell substrate adhesion GO:0010810 68 0.437
regulation of protein binding GO:0043393 66 0.434
regulation of wnt signaling pathway GO:0030111 123 0.433
regulation of kinase activity GO:0043549 314 0.431
positive regulation of catagen GO:0051795 2 0.431
negative regulation of programmed cell death GO:0043069 321 0.429
skeletal system development GO:0001501 79 0.428
neuroblast proliferation GO:0007405 4 0.428
cellular response to oxygen containing compound GO:1901701 276 0.425
response to carbohydrate GO:0009743 21 0.424
activation of protein kinase activity GO:0032147 90 0.424
response to drug GO:0042493 81 0.424
atrioventricular valve development GO:0003171 3 0.423
connective tissue development GO:0061448 39 0.422
response to other organism GO:0051707 261 0.422
actin filament based process GO:0030029 224 0.421
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.417
defense response to fungus GO:0050832 4 0.415
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.415
viral life cycle GO:0019058 132 0.414
mesenchymal cell differentiation GO:0048762 52 0.412
Human
gastrulation GO:0007369 51 0.404
regulation of phagocytosis engulfment GO:0060099 2 0.404
negative regulation of release of sequestered calcium ion into cytosol GO:0051280 1 0.403
positive regulation of phosphoprotein phosphatase activity GO:0032516 9 0.403
skin development GO:0043588 76 0.403
multicellular organismal signaling GO:0035637 34 0.401
purine nucleoside triphosphate metabolic process GO:0009144 412 0.400
regulation of transferase activity GO:0051338 355 0.400
appendage development GO:0048736 23 0.398
negative regulation of cell junction assembly GO:1901889 5 0.394
endocardial cell differentiation GO:0060956 2 0.393
hematopoietic or lymphoid organ development GO:0048534 186 0.391
negative regulation of muscle organ development GO:0048635 12 0.389
positive regulation of epithelial cell proliferation GO:0050679 65 0.388
renal system process GO:0003014 25 0.386
regulation of peptidase activity GO:0052547 180 0.385
regulation of epithelial cell proliferation GO:0050678 113 0.383
cellular response to lipopolysaccharide GO:0071222 57 0.382
positive regulation of transport GO:0051050 336 0.382
cell substrate junction assembly GO:0007044 35 0.382
cell morphogenesis GO:0000902 296 0.381
Human
regulation of actin cytoskeleton organization GO:0032956 116 0.379
system process GO:0003008 349 0.378
regulation of secretion by cell GO:1903530 177 0.376
myeloid leukocyte activation GO:0002274 34 0.373
peptidyl serine modification GO:0018209 106 0.371
craniofacial suture morphogenesis GO:0097094 3 0.370
regulation of cell adhesion mediated by integrin GO:0033628 22 0.368
actin cytoskeleton organization GO:0030036 207 0.368
tube morphogenesis GO:0035239 95 0.366
Mouse
positive regulation of cell death GO:0010942 263 0.365
cation transmembrane transport GO:0098655 238 0.361
leukocyte activation involved in immune response GO:0002366 30 0.361
respiratory system development GO:0060541 22 0.360
myeloid dendritic cell activation GO:0001773 4 0.358
positive regulation of b cell mediated immunity GO:0002714 4 0.357
endodermal cell differentiation GO:0035987 31 0.357
ribonucleotide biosynthetic process GO:0009260 81 0.356
inorganic cation transmembrane transport GO:0098662 194 0.353
regulation of cell differentiation GO:0045595 393 0.350
epithelial cell fate commitment GO:0072148 3 0.350
somitogenesis GO:0001756 2 0.349
divalent inorganic cation transport GO:0072511 158 0.348
endochondral bone morphogenesis GO:0060350 3 0.346
cell development GO:0048468 328 0.343
determination of dorsal ventral asymmetry GO:0048262 4 0.343
response to sterol GO:0036314 14 0.340
response to biotic stimulus GO:0009607 276 0.340
regulation of actin filament based process GO:0032970 141 0.338
lipoprotein metabolic process GO:0042157 42 0.337
regulation of striated muscle tissue development GO:0016202 26 0.336
negative regulation of striated muscle tissue development GO:0045843 11 0.335
response to glucose GO:0009749 19 0.334
morphogenesis of an epithelium GO:0002009 60 0.334
Mouse
cell activation involved in immune response GO:0002263 30 0.332
cell growth GO:0016049 160 0.331
embryonic heart tube morphogenesis GO:0003143 8 0.330
Mouse
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 8 0.329
regulation of cytoskeleton organization GO:0051493 177 0.329
lung development GO:0030324 20 0.326
positive regulation of smooth muscle cell differentiation GO:0051152 1 0.326
response to abiotic stimulus GO:0009628 336 0.325
regulation of myoblast differentiation GO:0045661 12 0.324
regulation of response to wounding GO:1903034 101 0.323
regulation of collagen metabolic process GO:0010712 15 0.323
positive regulation of immune system process GO:0002684 283 0.323
epithelium development GO:0060429 227 0.320
response to estrogen GO:0043627 47 0.320
maintenance of protein location GO:0045185 57 0.318
regulation of multi organism process GO:0043900 157 0.317
positive regulation of cytoplasmic transport GO:1903651 82 0.316
response to activity GO:0014823 0 0.315
wound healing spreading of cells GO:0044319 8 0.314
regulation of macrophage derived foam cell differentiation GO:0010743 14 0.313
signal transduction by phosphorylation GO:0023014 297 0.312
collagen activated signaling pathway GO:0038065 4 0.312
response to extracellular stimulus GO:0009991 85 0.312
positive regulation of kinase activity GO:0033674 204 0.311
negative regulation of binding GO:0051100 57 0.311
protein deacylation GO:0035601 39 0.307
chemical homeostasis GO:0048878 306 0.304
cell morphogenesis involved in differentiation GO:0000904 144 0.301
Human
cell cell junction organization GO:0045216 69 0.299
purine ribonucleoside metabolic process GO:0046128 437 0.298
branch elongation of an epithelium GO:0060602 3 0.297
muscle cell fate commitment GO:0042693 4 0.296
negative regulation of hyaluronan biosynthetic process GO:1900126 3 0.296
heterotypic cell cell adhesion GO:0034113 28 0.291
immune effector process GO:0002252 159 0.289
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.289
vascular wound healing GO:0061042 4 0.289
activin receptor signaling pathway GO:0032924 24 0.287
receptor biosynthetic process GO:0032800 18 0.285
negative regulation of protein metabolic process GO:0051248 391 0.285
regulation of keratinocyte migration GO:0051547 4 0.284
regulation of vesicle mediated transport GO:0060627 130 0.283
tissue morphogenesis GO:0048729 96 0.283
Mouse
secretion by cell GO:0032940 226 0.283
negative regulation of developmental process GO:0051093 247 0.282
regulation of intracellular transport GO:0032386 195 0.280
regulation of endocytosis GO:0030100 72 0.280
response to hexose GO:0009746 20 0.279
cellular response to dexamethasone stimulus GO:0071549 1 0.278
gland development GO:0048732 48 0.277
kidney epithelium development GO:0072073 25 0.277
regulation of phosphatase activity GO:0010921 81 0.276
positive regulation of peptidase activity GO:0010952 88 0.275
epithelial cell development GO:0002064 34 0.268
positive regulation of endothelial cell proliferation GO:0001938 37 0.268
response to decreased oxygen levels GO:0036293 96 0.266
pathway restricted smad protein phosphorylation GO:0060389 38 0.264
receptor catabolic process GO:0032801 11 0.262
negative regulation of muscle tissue development GO:1901862 11 0.261
response to hormone GO:0009725 175 0.261
Human
negative regulation of protein binding GO:0032091 35 0.259
entry into host cell GO:0030260 25 0.259
regulation of cell substrate junction assembly GO:0090109 20 0.258
regulation of feeding behavior GO:0060259 3 0.258
regulation of behavior GO:0050795 82 0.258
limb development GO:0060173 23 0.258
regeneration GO:0031099 4 0.257
response to cytokine GO:0034097 232 0.254
regulation of mapk cascade GO:0043408 262 0.254
growth GO:0040007 202 0.253
epithelial cell proliferation GO:0050673 128 0.253
mitotic cell cycle phase transition GO:0044772 162 0.252
positive regulation of integrin biosynthetic process GO:0045726 3 0.249
determination of adult lifespan GO:0008340 2 0.249
tube development GO:0035295 125 0.249
Mouse
positive regulation of keratinocyte migration GO:0051549 4 0.248
positive regulation of cell adhesion mediated by integrin GO:0033630 9 0.247
somite development GO:0061053 7 0.246
innate immune response GO:0045087 178 0.242
lens fiber cell differentiation GO:0070306 2 0.242
defense response GO:0006952 315 0.240
regulation of angiogenesis GO:0045765 92 0.239
Mouse
gland morphogenesis GO:0022612 8 0.239
regulation of neuroblast proliferation GO:1902692 3 0.237
cell cycle phase transition GO:0044770 173 0.235
protein catabolic process GO:0030163 325 0.235
calcium independent cell matrix adhesion GO:0007161 1 0.234
cellular response to organic cyclic compound GO:0071407 127 0.232
smad protein import into nucleus GO:0007184 13 0.230
common partner smad protein phosphorylation GO:0007182 3 0.230
nucleoside phosphate biosynthetic process GO:1901293 109 0.229
defense response to other organism GO:0098542 129 0.228
mesonephric tubule morphogenesis GO:0072171 10 0.228
nucleotide biosynthetic process GO:0009165 109 0.228
leukocyte activation GO:0045321 164 0.227
cardiac muscle cell proliferation GO:0060038 6 0.226
respiratory tube development GO:0030323 20 0.226
regulation of protein localization to plasma membrane GO:1903076 40 0.225
heart morphogenesis GO:0003007 48 0.224
Human Mouse
embryonic cranial skeleton morphogenesis GO:0048701 6 0.224
glycosaminoglycan catabolic process GO:0006027 8 0.224
positive regulation of response to wounding GO:1903036 28 0.223
neuronal action potential GO:0019228 9 0.222
response to nutrient GO:0007584 20 0.222
response to external biotic stimulus GO:0043207 261 0.222
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.219
negative regulation of multi organism process GO:0043901 92 0.218
purine nucleotide biosynthetic process GO:0006164 84 0.217
lipid localization GO:0010876 106 0.217
sodium ion transport GO:0006814 61 0.217
post embryonic development GO:0009791 2 0.216
branching morphogenesis of an epithelial tube GO:0048754 19 0.215
Mouse
positive regulation of stress activated mapk cascade GO:0032874 60 0.213
cell cycle checkpoint GO:0000075 117 0.213
macromolecule deacylation GO:0098732 41 0.211
regulation of endothelial cell differentiation GO:0045601 4 0.210
cellular response to molecule of bacterial origin GO:0071219 62 0.209
myeloid leukocyte cytokine production GO:0061082 5 0.209
cellular response to alcohol GO:0097306 29 0.209
regulation of collagen catabolic process GO:0010710 3 0.209
regulation of protein kinase b signaling GO:0051896 61 0.208
tissue remodeling GO:0048771 16 0.208
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.207
ribonucleoside triphosphate metabolic process GO:0009199 412 0.206
bmp signaling pathway GO:0030509 49 0.204
positive regulation of cellular component biogenesis GO:0044089 158 0.204
response to molecule of bacterial origin GO:0002237 82 0.204
cyclic nucleotide metabolic process GO:0009187 82 0.201

ENG disease predictions

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 88 0.382
musculoskeletal system disease DOID:17 223 0.382
connective tissue disease DOID:65 109 0.382
bone remodeling disease DOID:0080005 26 0.249