IMP

Process View

Homo sapiens

20 genes annotated in human

regulation of cell substrate junction assembly

Any process that modulates the rate, frequency, or extent of cell-substrate junction assembly. Cell-substrate junction assembly is the aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cell substrate junction assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of cell substrate junction assembly" (in gray)

Name	Description	Probability	Func Analog Organism
S100A6	S100 calcium binding protein A6	0.963	Human
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.961	Human
PTK2	PTK2 protein tyrosine kinase 2	0.895
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.815
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.713	Human
ANGPT2	angiopoietin 2	0.672
S100B	S100 calcium binding protein B	0.658	Human
S100A1	S100 calcium binding protein A1	0.566	Human
SMAD2	SMAD family member 2	0.548
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.482	Human
NRP1	neuropilin 1	0.358
ANXA2	annexin A2	0.344
EGFR	epidermal growth factor receptor	0.326
VEGFA	vascular endothelial growth factor A	0.317
FKBP1A	FK506 binding protein 1A, 12kDa	0.316
NCK2	NCK adaptor protein 2	0.307
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.298	Human
ENG	endoglin	0.258
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.257
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.255
BCAR1	breast cancer anti-estrogen resistance 1	0.194
BMP2	bone morphogenetic protein 2	0.188
EPHA7	EPH receptor A7	0.185	Human
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.150
SMAD7	SMAD family member 7	0.148
S100A11	S100 calcium binding protein A11	0.139	Human
LIMS1	LIM and senescent cell antigen-like domains 1	0.138
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.131	Human
DPYSL4	dihydropyrimidinase-like 4	0.129
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.128
EPHA2	EPH receptor A2	0.128	Human
S100A4	S100 calcium binding protein A4	0.127	Human
ANGPT1	angiopoietin 1	0.100
RHOA	ras homolog gene family, member A	0.097
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	0.090
PDGFA	platelet-derived growth factor alpha polypeptide	0.086	Human
GRB7	growth factor receptor-bound protein 7	0.081
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.079
EFNA1	ephrin-A1	0.074	Human
PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	0.073
AREG	amphiregulin	0.065
FKBP4	FK506 binding protein 4, 59kDa	0.063
GDF5	growth differentiation factor 5	0.063
PDGFC	platelet derived growth factor C	0.061
FYN	FYN oncogene related to SRC, FGR, YES	0.056
PLCG1	phospholipase C, gamma 1	0.052
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.051
PHC2	polyhomeotic homolog 2 (Drosophila)	0.049
ATF7IP	activating transcription factor 7 interacting protein	0.046
KITLG	KIT ligand	0.045
AGER	advanced glycosylation end product-specific receptor	0.045
JAG1	jagged 1	0.044
CAPG	capping protein (actin filament), gelsolin-like	0.044
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.039
TGFB1	transforming growth factor, beta 1	0.038
PRKG1	protein kinase, cGMP-dependent, type I	0.036
TSC2	tuberous sclerosis 2	0.035
TGFB3	transforming growth factor, beta 3	0.035
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.032
PGF	placental growth factor	0.032	Human
HOXA1	homeobox A1	0.032
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.031
EFNA5	ephrin-A5	0.031
BMPR1A	bone morphogenetic protein receptor, type IA	0.030	Human
ZNF746	zinc finger protein 746	0.030
TRIP6	thyroid hormone receptor interactor 6	0.030
LPXN	leupaxin	0.029	Human
ACVR1	activin A receptor, type I	0.029	Human
GAB1	GRB2-associated binding protein 1	0.028
PVRL3	poliovirus receptor-related 3	0.028
PTPRB	protein tyrosine phosphatase, receptor type, B	0.027	Human
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.026
BMP4	bone morphogenetic protein 4	0.026
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.025	Rat
S100A2	S100 calcium binding protein A2	0.024	Human
ILK	integrin-linked kinase	0.023
CDH5	cadherin 5, type 2 (vascular endothelium)	0.023
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.022	Human
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.022
CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	0.021
FURIN	furin (paired basic amino acid cleaving enzyme)	0.020
LDLR	low density lipoprotein receptor	0.020
CTNND1	catenin (cadherin-associated protein), delta 1	0.020
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.020
CNKSR1	connector enhancer of kinase suppressor of Ras 1	0.020
S100A10	S100 calcium binding protein A10	0.020
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.020
CAV1	caveolin 1, caveolae protein, 22kDa	0.019
LGALS3	lectin, galactoside-binding, soluble, 3	0.019
CXXC5	CXXC finger protein 5	0.019
LAT	linker for activation of T cells	0.018
LIMK1	LIM domain kinase 1	0.018
EPHB3	EPH receptor B3	0.017	Human
GHR	growth hormone receptor	0.017
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.017
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.017
SORBS3	sorbin and SH3 domain containing 3	0.017
ZMYND11	zinc finger, MYND-type containing 11	0.016
EPHB2	EPH receptor B2	0.016	Human
FAF1	Fas (TNFRSF6) associated factor 1	0.016
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.015
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.015	Human
EPHA3	EPH receptor A3	0.015
LMO2	LIM domain only 2 (rhombotin-like 1)	0.015
S100P	S100 calcium binding protein P	0.014	Human
ITGA7	integrin, alpha 7	0.014
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.014
MRAS	muscle RAS oncogene homolog	0.014
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.014
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.014	Human
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.014
PLP2	proteolipid protein 2 (colonic epithelium-enriched)	0.013
RHOC	ras homolog gene family, member C	0.013
DIAPH1	diaphanous homolog 1 (Drosophila)	0.013
MAPK8	mitogen-activated protein kinase 8	0.013
BMP1	bone morphogenetic protein 1	0.013
GRB10	growth factor receptor-bound protein 10	0.013
FHL2	four and a half LIM domains 2	0.013
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.013
PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	0.013
TGFBR1	transforming growth factor, beta receptor 1	0.013	Human
PHF21A	PHD finger protein 21A	0.012
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.012
FXYD5	FXYD domain containing ion transport regulator 5	0.012
TSG101	tumor susceptibility gene 101	0.012
RHOG	ras homolog gene family, member G (rho G)	0.011	Human
ADRBK1	adrenergic, beta, receptor kinase 1	0.011
PAWR	PRKC, apoptosis, WT1, regulator	0.011
RHOU	ras homolog gene family, member U	0.011
ZNF426	zinc finger protein 426	0.011
MYH11	myosin, heavy chain 11, smooth muscle	0.011
AHNAK	AHNAK nucleoprotein	0.011
IGF2	insulin-like growth factor 2 (somatomedin A)	0.011
SKIL	SKI-like oncogene	0.011
ACVR1B	activin A receptor, type IB	0.011	Human
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.010