IMP

Process View

Homo sapiens

24 genes annotated in human

viral entry into host cell

The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "viral entry into host cell"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "viral entry into host cell" (in gray)

Name	Description	Probability	Func Analog Organism
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.999
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.999
IFITM2	interferon induced transmembrane protein 2 (1-8D)	0.847
IFITM3	interferon induced transmembrane protein 3 (1-8U)	0.814
TRIM39	tripartite motif containing 39	0.695	Human
ENG	endoglin	0.584
FHL2	four and a half LIM domains 2	0.526
FN1	fibronectin 1	0.481
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.481
MED15	mediator complex subunit 15	0.462
TLN1	talin 1	0.341
AXL	AXL receptor tyrosine kinase	0.282
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.278
IFITM1	interferon induced transmembrane protein 1 (9-27)	0.266
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	0.241	Human
TRIM43	tripartite motif containing 43	0.237
PVRL4	poliovirus receptor-related 4	0.225
PXN	paxillin	0.202
PDIA3	protein disulfide isomerase family A, member 3	0.134
RNF5	ring finger protein 5	0.126
PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	0.114
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.097
TGFB1	transforming growth factor, beta 1	0.097
KDM6A	lysine (K)-specific demethylase 6A	0.092
PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	0.090
ZNRF1	zinc and ring finger 1	0.090
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.082
TRIM41	tripartite motif containing 41	0.071	Human
NAMPT	nicotinamide phosphoribosyltransferase	0.071
BST2	bone marrow stromal cell antigen 2	0.070
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.070
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.063
PVRL3	poliovirus receptor-related 3	0.062	Human
FLNA	filamin A, alpha	0.060
ITGB4	integrin, beta 4	0.060
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.059
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.058
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.057	Human
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.056
THBS1	thrombospondin 1	0.056
TRIM8	tripartite motif containing 8	0.054	Mouse
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.052
GCC1	GRIP and coiled-coil domain containing 1	0.052
MAGEA4	melanoma antigen family A, 4	0.049
IRF9	interferon regulatory factor 9	0.046
TRIM26	tripartite motif containing 26	0.043
RNF126	ring finger protein 126	0.042
EFCAB4B	EF-hand calcium binding domain 4B	0.041
XIAP	X-linked inhibitor of apoptosis	0.041
TIMP1	TIMP metallopeptidase inhibitor 1	0.033
ZNF473	zinc finger protein 473	0.029
IFI16	interferon, gamma-inducible protein 16	0.029
BTN3A2	butyrophilin, subfamily 3, member A2	0.028
CD63	CD63 molecule	0.028
FBF1	Fas (TNFRSF6) binding factor 1	0.028
PML	promyelocytic leukemia	0.026
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.026
PLSCR1	phospholipid scramblase 1	0.026
SP110	SP110 nuclear body protein	0.025
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.024
IFNA16	interferon, alpha 16	0.022	Human
TRIM21	tripartite motif containing 21	0.021	Human Mouse
RNF11	ring finger protein 11	0.021
DYDC1	DPY30 domain containing 1	0.021
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.020
RNF181	ring finger protein 181	0.020
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.020
TRIM17	tripartite motif containing 17	0.020	Human
TRIM52	tripartite motif containing 52	0.020
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.018
ABHD16A	abhydrolase domain containing 16A	0.018
CD9	CD9 molecule	0.018
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.018
FAS	Fas (TNF receptor superfamily, member 6)	0.017
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.017
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.016
TRIM32	tripartite motif containing 32	0.016
COL17A1	collagen, type XVII, alpha 1	0.016
VCAM1	vascular cell adhesion molecule 1	0.016
TSGA10	testis specific, 10	0.015
STX7	syntaxin 7	0.015
ADAM9	ADAM metallopeptidase domain 9	0.015
EPHA2	EPH receptor A2	0.014
TRIM35	tripartite motif containing 35	0.014
IFNA10	interferon, alpha 10	0.014	Human
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.014
TRIM25	tripartite motif containing 25	0.014
RNF10	ring finger protein 10	0.014
ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	0.014
HLA-E	major histocompatibility complex, class I, E	0.014
ITGB5	integrin, beta 5	0.013
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	0.013
C19orf66	chromosome 19 open reading frame 66	0.013
RNF31	ring finger protein 31	0.013
SHISA5	shisa homolog 5 (Xenopus laevis)	0.013
ZBTB8A	zinc finger and BTB domain containing 8A	0.013
MKRN3	makorin ring finger protein 3	0.013
SH3BGRL	SH3 domain binding glutamic acid-rich protein like	0.013
UBTD1	ubiquitin domain containing 1	0.012
TJP1	tight junction protein 1 (zona occludens 1)	0.012
TRIM5	tripartite motif containing 5	0.012
WFDC2	WAP four-disulfide core domain 2	0.012
RNF130	ring finger protein 130	0.011
CRP	C-reactive protein, pentraxin-related	0.011	Human
SP100	SP100 nuclear antigen	0.011
RNF32	ring finger protein 32	0.011
RNF185	ring finger protein 185	0.011
C4BPA	complement component 4 binding protein, alpha	0.011
TMPRSS4	transmembrane protease, serine 4	0.011	Human
ANXA1	annexin A1	0.011
MCOLN1	mucolipin 1	0.011
IFNA4	interferon, alpha 4	0.011
ITGB1BP1	integrin beta 1 binding protein 1	0.011
MEX3B	mex-3 homolog B (C. elegans)	0.011
ITGA7	integrin, alpha 7	0.011
RNF111	ring finger protein 111	0.011
MAGEA1	melanoma antigen family A, 1 (directs expression of antigen MZ2-E)	0.011
APCS	amyloid P component, serum	0.011
EIF1AY	eukaryotic translation initiation factor 1A, Y-linked	0.011
MID1	midline 1 (Opitz/BBB syndrome)	0.010	Human
LY6E	lymphocyte antigen 6 complex, locus E	0.010
TRIM6-TRIM34	TRIM6-TRIM34 readthrough	0.010
BFAR	bifunctional apoptosis regulator	0.010
STX4	syntaxin 4	0.010
MGRN1	mahogunin, ring finger 1	0.010
LAD1	ladinin 1	0.010