Homo sapiens

63 known processes

MYD88

myeloid differentiation primary response gene (88)

(Aliases: MYD88D)

MYD88 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to bacterial lipoprotein GO:0071220 3 1.000
cellular response to triacyl bacterial lipopeptide GO:0071727 2 1.000
response to triacyl bacterial lipopeptide GO:0071725 2 1.000
positive regulation of toll like receptor signaling pathway GO:0034123 10 1.000
detection of bacterial lipoprotein GO:0042494 3 1.000
response to diacyl bacterial lipopeptide GO:0071724 2 1.000
detection of diacyl bacterial lipopeptide GO:0042496 2 1.000
interferon alpha biosynthetic process GO:0045349 4 1.000
cellular response to diacyl bacterial lipopeptide GO:0071726 2 1.000
response to bacterial lipopeptide GO:0070339 3 1.000
toll like receptor 2 signaling pathway GO:0034134 4 1.000
positive regulation of toll like receptor 4 signaling pathway GO:0034145 6 1.000
interleukin 6 production GO:0032635 37 1.000
Mouse
innate immune response activating signal transduction GO:0002758 48 1.000
Mouse
cellular response to bacterial lipopeptide GO:0071221 3 1.000
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 4 1.000
i kappab phosphorylation GO:0007252 7 1.000
response to bacterial lipoprotein GO:0032493 3 1.000
activation of innate immune response GO:0002218 55 1.000
Zebrafish Mouse
growth of symbiont in host GO:0044117 1 1.000
Mouse
detection of bacterial lipopeptide GO:0070340 3 1.000
positive regulation of toll like receptor 2 signaling pathway GO:0034137 2 1.000
regulation of i kappab kinase nf kappab signaling GO:0043122 162 1.000
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 1.000
Mouse
regulation of interferon alpha biosynthetic process GO:0045354 4 0.999
regulation of cytokine production GO:0001817 232 0.999
Mouse
pattern recognition receptor signaling pathway GO:0002221 48 0.999
Mouse
positive regulation of interferon beta biosynthetic process GO:0045359 4 0.999
innate immune response GO:0045087 178 0.999
Zebrafish Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.999
Mouse
positive regulation of interferon alpha biosynthetic process GO:0045356 4 0.999
response to biotic stimulus GO:0009607 276 0.999
Zebrafish Mouse Fly
regulation of defense response GO:0031347 154 0.999
Zebrafish Mouse Fly
regulation of tumor necrosis factor production GO:0032680 43 0.999
Mouse
positive regulation of innate immune response GO:0045089 79 0.998
Zebrafish Mouse
detection of triacyl bacterial lipopeptide GO:0042495 2 0.998
negative regulation of tumor necrosis factor production GO:0032720 20 0.998
regulation of chemokine production GO:0032642 31 0.997
Mouse
cytokine production GO:0001816 247 0.997
Mouse
immune effector process GO:0002252 159 0.997
Mouse Fly
regulation of interleukin 6 production GO:0032675 37 0.997
Mouse
response to peptidoglycan GO:0032494 3 0.997
Mouse
response to lipoteichoic acid GO:0070391 3 0.997
response to external biotic stimulus GO:0043207 261 0.997
Zebrafish Mouse Fly
immune response activating signal transduction GO:0002757 90 0.996
Mouse
response to cytokine GO:0034097 232 0.996
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.996
Mouse
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.996
regulation of interferon beta biosynthetic process GO:0045357 4 0.996
positive regulation of chemokine production GO:0032722 22 0.995
Mouse
response to other organism GO:0051707 261 0.995
Zebrafish Mouse Fly
regulation of toll like receptor 2 signaling pathway GO:0034135 2 0.995
positive regulation of interleukin 8 production GO:0032757 36 0.995
tumor necrosis factor production GO:0032640 43 0.995
Mouse
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.995
Mouse
activation of immune response GO:0002253 114 0.994
Zebrafish Mouse
defense response GO:0006952 315 0.993
Zebrafish Mouse Fly
defense response to virus GO:0051607 71 0.992
i kappab kinase nf kappab signaling GO:0007249 166 0.992
response to lipid GO:0033993 206 0.991
Mouse
detection of molecule of bacterial origin GO:0032490 10 0.991
toll like receptor signaling pathway GO:0002224 25 0.990
Mouse
regulation of growth of symbiont in host GO:0044126 1 0.990
Mouse
positive regulation of defense response GO:0031349 87 0.990
Zebrafish Mouse Fly
response to lipopolysaccharide GO:0032496 70 0.990
Mouse
cellular response to molecule of bacterial origin GO:0071219 62 0.986
Mouse
response to bacterium GO:0009617 144 0.985
Zebrafish Mouse Fly
positive regulation of cytokine production GO:0001819 167 0.984
Mouse
positive regulation of toll like receptor 3 signaling pathway GO:0034141 1 0.981
immune response GO:0006955 307 0.981
Zebrafish Mouse Fly
immune response regulating signaling pathway GO:0002764 97 0.979
Mouse
toll like receptor 4 signaling pathway GO:0034142 12 0.979
cellular response to oxygen containing compound GO:1901701 276 0.979
Mouse
response to molecule of bacterial origin GO:0002237 82 0.979
Zebrafish Mouse
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.977
Mouse
defense response to other organism GO:0098542 129 0.975
Mouse Fly
regulation of interferon beta production GO:0032648 22 0.975
cellular response to mechanical stimulus GO:0071260 39 0.971
type i interferon biosynthetic process GO:0045351 4 0.970
Mouse
chemokine production GO:0032602 32 0.970
Mouse
detection of lipopolysaccharide GO:0032497 3 0.968
regulation of interleukin 12 production GO:0032655 15 0.966
positive regulation of immune response GO:0050778 159 0.966
Zebrafish Mouse Fly
regulation of innate immune response GO:0045088 97 0.958
Zebrafish Mouse
defense response to bacterium GO:0042742 63 0.956
Mouse Fly
regulation of lipopolysaccharide mediated signaling pathway GO:0031664 13 0.956
positive regulation of interferon beta production GO:0032728 17 0.955
positive regulation of map kinase activity GO:0043406 80 0.952
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.951
Mouse
positive regulation of nf kappab import into nucleus GO:0042346 13 0.943
cytokine mediated signaling pathway GO:0019221 109 0.942
Rat
cellular response to biotic stimulus GO:0071216 71 0.939
Mouse
type i interferon production GO:0032606 27 0.936
Mouse
interspecies interaction between organisms GO:0044419 156 0.933
Mouse
positive regulation of tumor necrosis factor production GO:0032760 21 0.932
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.928
interleukin 12 production GO:0032615 15 0.926
modulation of growth of symbiont involved in interaction with host GO:0044144 2 0.925
Mouse
interleukin 8 production GO:0032637 51 0.914
response to nitrogen compound GO:1901698 184 0.914
Mouse
response to oxygen containing compound GO:1901700 369 0.913
Mouse
regulation of cytokine mediated signaling pathway GO:0001959 41 0.908
negative regulation of cholesterol transport GO:0032375 8 0.906
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.905
Mouse
intracellular protein transport GO:0006886 270 0.902
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.901
Mouse
activation of protein kinase activity GO:0032147 90 0.898
positive regulation of interleukin 8 biosynthetic process GO:0045416 8 0.897
cellular response to lipopolysaccharide GO:0071222 57 0.893
Mouse
regulation of mapk cascade GO:0043408 262 0.890
Mouse
regulation of multi organism process GO:0043900 157 0.886
Mouse Fly
regulation of immune effector process GO:0002697 91 0.885
Fly
regulation of transferase activity GO:0051338 355 0.884
regulation of protein targeting GO:1903533 91 0.879
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.879
regulation of jnk cascade GO:0046328 73 0.874
Mouse
apoptotic signaling pathway GO:0097190 268 0.870
positive regulation of jnk cascade GO:0046330 52 0.869
Mouse
positive regulation of immune system process GO:0002684 283 0.869
Zebrafish Mouse Fly
regulation of interferon alpha production GO:0032647 11 0.868
positive regulation of phosphorylation GO:0042327 394 0.867
Mouse
reactive nitrogen species metabolic process GO:2001057 3 0.865
cellular response to lipid GO:0071396 127 0.857
Mouse
negative regulation of protein modification process GO:0031400 200 0.851
positive regulation of interferon alpha production GO:0032727 11 0.850
detection of external biotic stimulus GO:0098581 19 0.849
negative regulation of interleukin 6 production GO:0032715 13 0.848
defense response to gram positive bacterium GO:0050830 29 0.840
Mouse Fly
regulation of toll like receptor signaling pathway GO:0034121 17 0.830
negative regulation of tumor necrosis factor superfamily cytokine production GO:1903556 20 0.808
regulation of type i interferon production GO:0032479 26 0.805
negative regulation of interleukin 17 production GO:0032700 5 0.802
cellular response to external stimulus GO:0071496 111 0.798
negative regulation of multi organism process GO:0043901 92 0.797
Mouse
regulation of macrophage cytokine production GO:0010935 4 0.787
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.778
Mouse
nucleocytoplasmic transport GO:0006913 176 0.776
regulation of interleukin 17 production GO:0032660 12 0.775
Mouse
positive regulation of programmed cell death GO:0043068 249 0.772
positive regulation of transferase activity GO:0051347 227 0.770
regulation of kinase activity GO:0043549 314 0.768
regulation of interleukin 8 production GO:0032677 49 0.752
interleukin 17 production GO:0032620 12 0.750
Mouse
regulation of intracellular transport GO:0032386 195 0.747
regulation of protein serine threonine kinase activity GO:0071900 179 0.741
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.739
Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.738
negative regulation of transport GO:0051051 176 0.736
positive regulation of type i interferon production GO:0032481 20 0.733
purine nucleotide biosynthetic process GO:0006164 84 0.730
nucleotide binding oligomerization domain containing signaling pathway GO:0070423 4 0.721
negative regulation of phosphorus metabolic process GO:0010563 267 0.708
negative regulation of cytokine production GO:0001818 82 0.705
regulation of cell activation GO:0050865 125 0.695
Mouse
protein autophosphorylation GO:0046777 123 0.693
positive regulation of cytokine biosynthetic process GO:0042108 25 0.692
Mouse
nuclear import GO:0051170 106 0.690
regulation of immune response GO:0050776 201 0.687
Zebrafish Mouse Fly
response to organonitrogen compound GO:0010243 156 0.681
Mouse
transcription factor import into nucleus GO:0042991 40 0.681
leukocyte proliferation GO:0070661 74 0.670
Mouse
protein catabolic process GO:0030163 325 0.669
positive regulation of protein import into nucleus GO:0042307 46 0.665
positive regulation of cell proliferation GO:0008284 301 0.652
Mouse Rat
regulation of cellular response to stress GO:0080135 244 0.648
Mouse
positive regulation of jun kinase activity GO:0043507 23 0.646
positive regulation of protein kinase activity GO:0045860 190 0.643
detection of chemical stimulus GO:0009593 55 0.629
stress activated mapk cascade GO:0051403 93 0.626
Mouse Rat
positive regulation of apoptotic process GO:0043065 246 0.612
signal transduction by phosphorylation GO:0023014 297 0.594
Mouse Rat
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.587
positive regulation of transcription factor import into nucleus GO:0042993 25 0.585
regulation of protein kinase activity GO:0045859 289 0.584
tissue homeostasis GO:0001894 63 0.571
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.565
negative regulation of phosphorylation GO:0042326 174 0.556
interferon beta production GO:0032608 23 0.553
regulation of stress activated mapk cascade GO:0032872 84 0.550
Mouse
cytoplasmic transport GO:0016482 379 0.549
protein targeting GO:0006605 187 0.548
negative regulation of catalytic activity GO:0043086 335 0.544
regulation of leukocyte activation GO:0002694 115 0.542
Mouse
regulation of protein localization GO:0032880 296 0.541
protein complex localization GO:0031503 31 0.536
lymphocyte activation GO:0046649 133 0.534
Mouse
nuclear transport GO:0051169 179 0.532
regulation of dna binding GO:0051101 37 0.532
positive regulation of response to external stimulus GO:0032103 88 0.523
Fly
regulation of transcription factor import into nucleus GO:0042990 39 0.522
stress activated protein kinase signaling cascade GO:0031098 94 0.521
Mouse Rat
amide transport GO:0042886 76 0.519
positive regulation of interleukin 1 production GO:0032732 14 0.509
regulation of response to cytokine stimulus GO:0060759 46 0.507
growth involved in symbiotic interaction GO:0044110 2 0.507
Mouse
negative regulation of protein metabolic process GO:0051248 391 0.506
positive regulation of interferon gamma production GO:0032729 26 0.497
positive regulation of interleukin 6 production GO:0032755 21 0.494
Mouse
negative regulation of immune system process GO:0002683 136 0.494
protein import GO:0017038 130 0.491
positive regulation of protein phosphorylation GO:0001934 313 0.482
regulation of protein transport GO:0051223 213 0.479
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.473
protein localization to organelle GO:0033365 280 0.471
response to abiotic stimulus GO:0009628 336 0.470
leukocyte activation GO:0045321 164 0.469
Mouse
positive regulation of cytoplasmic transport GO:1903651 82 0.467
negative regulation of cellular component organization GO:0051129 235 0.462
cellular response to cytokine stimulus GO:0071345 181 0.455
Rat
type i interferon signaling pathway GO:0060337 11 0.455
protein oligomerization GO:0051259 173 0.451
leukocyte migration GO:0050900 107 0.443
lymphocyte mediated immunity GO:0002449 48 0.442
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.438
Mouse
regulation of cytoplasmic transport GO:1903649 149 0.431
regulation of protein catabolic process GO:0042176 155 0.424
mononuclear cell proliferation GO:0032943 71 0.422
Mouse
regulation of intracellular protein transport GO:0033157 123 0.422
negative regulation of cellular protein metabolic process GO:0032269 353 0.418
positive regulation of hemostasis GO:1900048 11 0.417
regulation of nucleocytoplasmic transport GO:0046822 98 0.413
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.413
response to oxidative stress GO:0006979 121 0.410
regulation of map kinase activity GO:0043405 108 0.402
cellular amino acid metabolic process GO:0006520 116 0.401
granulocyte migration GO:0097530 40 0.392
positive regulation of lymphocyte proliferation GO:0050671 46 0.387
Mouse
detection of biotic stimulus GO:0009595 21 0.386
positive regulation of cellular amine metabolic process GO:0033240 7 0.377
growth of symbiont involved in interaction with host GO:0044116 2 0.372
Mouse
positive regulation of nik nf kappab signaling GO:1901224 10 0.370
positive regulation of cytokine mediated signaling pathway GO:0001961 12 0.369
response to virus GO:0009615 126 0.368
Mouse
response to oxygen levels GO:0070482 100 0.358
negative regulation of transferase activity GO:0051348 124 0.356
jnk cascade GO:0007254 80 0.352
Mouse Rat
positive regulation of production of molecular mediator of immune response GO:0002702 11 0.347
Fly
nf kappab import into nucleus GO:0042348 22 0.347
cellular response to lipoteichoic acid GO:0071223 3 0.344
regulation of nf kappab import into nucleus GO:0042345 22 0.330
cellular ketone metabolic process GO:0042180 80 0.313
response to interleukin 1 GO:0070555 47 0.312
interleukin 6 biosynthetic process GO:0042226 5 0.309
nitrogen compound transport GO:0071705 191 0.305
negative regulation of intracellular signal transduction GO:1902532 183 0.304
cellular amine metabolic process GO:0044106 41 0.304
intracellular receptor signaling pathway GO:0030522 104 0.304
negative regulation of protein phosphorylation GO:0001933 140 0.301
cellular response to abiotic stimulus GO:0071214 117 0.296
negative regulation of catabolic process GO:0009895 104 0.296
regulation of viral process GO:0050792 103 0.296
negative regulation of interleukin 12 production GO:0032695 6 0.294
protein homooligomerization GO:0051260 100 0.291
positive regulation of stress activated mapk cascade GO:0032874 60 0.290
Mouse
regulation of cellular ketone metabolic process GO:0010565 50 0.289
regulation of protein localization to nucleus GO:1900180 85 0.288
regulation of establishment of protein localization GO:0070201 242 0.287
inflammatory response GO:0006954 79 0.282
Mouse
macrophage activation GO:0042116 12 0.282
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.281
nik nf kappab signaling GO:0038061 12 0.275
positive regulation of apoptotic signaling pathway GO:2001235 70 0.275
skeletal muscle contraction GO:0003009 16 0.275
positive regulation of interferon gamma biosynthetic process GO:0045078 7 0.270
regulation of mononuclear cell proliferation GO:0032944 65 0.269
Mouse
regulation of cytokine production involved in immune response GO:0002718 22 0.268
negative regulation of growth of symbiont involved in interaction with host GO:0044146 2 0.264
Mouse
negative regulation of production of molecular mediator of immune response GO:0002701 13 0.262
negative regulation of mapk cascade GO:0043409 56 0.261
positive regulation of mapk cascade GO:0043410 190 0.261
Mouse
cytokine biosynthetic process GO:0042089 37 0.260
Mouse
detection of other organism GO:0098543 13 0.260
response to fungus GO:0009620 4 0.259
Mouse Fly
positive regulation of cell death GO:0010942 263 0.258
regulation of response to biotic stimulus GO:0002831 55 0.257
Fly
negative regulation of growth GO:0045926 97 0.256
Mouse
mapk cascade GO:0000165 288 0.252
Mouse Rat
mhc class ii biosynthetic process GO:0045342 4 0.245
detection of stimulus GO:0051606 85 0.245
protein import into nucleus GO:0006606 104 0.242
organic hydroxy compound transport GO:0015850 63 0.241
regulation of cellular amino acid metabolic process GO:0006521 6 0.239
protein targeting to nucleus GO:0044744 104 0.238
cellular response to interleukin 1 GO:0071347 35 0.232
cytokine metabolic process GO:0042107 38 0.219
Mouse
regulation of protein import into nucleus GO:0042306 78 0.218
single organism cellular localization GO:1902580 332 0.214
negative regulation of protein catabolic process GO:0042177 59 0.213
response to activity GO:0014823 0 0.211
defense response to fungus GO:0050832 4 0.211
Fly
fatty acid metabolic process GO:0006631 115 0.209
positive regulation of intracellular transport GO:0032388 104 0.206
negative regulation of cholesterol efflux GO:0090370 2 0.205
regulation of locomotion GO:0040012 329 0.204
viral life cycle GO:0019058 132 0.203
nucleotide binding oligomerization domain containing 2 signaling pathway GO:0070431 4 0.203
amine metabolic process GO:0009308 44 0.201
regulation of apoptotic signaling pathway GO:2001233 175 0.201
regulation of response to external stimulus GO:0032101 222 0.198
Mouse Fly
peptide transport GO:0015833 74 0.192
regulation of nik nf kappab signaling GO:1901222 11 0.189
anatomical structure homeostasis GO:0060249 100 0.189
negative regulation of map kinase activity GO:0043407 27 0.189
lymphocyte proliferation GO:0046651 70 0.189
Mouse
myeloid leukocyte activation GO:0002274 34 0.185
positive regulation of interleukin 6 biosynthetic process GO:0045410 1 0.179
peripheral nervous system development GO:0007422 2 0.179
positive regulation of mononuclear cell proliferation GO:0032946 47 0.178
Mouse
3 utr mediated mrna stabilization GO:0070935 8 0.176
regulation of b cell activation GO:0050864 24 0.174
positive regulation of interleukin 12 production GO:0032735 8 0.173
negative regulation of protein complex disassembly GO:0043242 20 0.170
response to organic cyclic compound GO:0014070 204 0.168
negative regulation of viral process GO:0048525 66 0.167
regulation of peptide transport GO:0090087 62 0.165
cellular macromolecule catabolic process GO:0044265 380 0.165
interferon alpha production GO:0032607 11 0.162
positive regulation of b cell activation GO:0050871 17 0.157
multicellular organismal aging GO:0010259 3 0.156
viral process GO:0016032 146 0.154
neutrophil migration GO:1990266 25 0.154
rna stabilization GO:0043489 18 0.153
protein ubiquitination GO:0016567 314 0.150
regulation of cellular amine metabolic process GO:0033238 11 0.148
positive regulation of neutrophil migration GO:1902624 7 0.147
cell activation GO:0001775 213 0.146
Mouse
interferon gamma production GO:0032609 39 0.146
positive regulation of protein localization to nucleus GO:1900182 48 0.146
negative regulation of protein maturation GO:1903318 142 0.142
regulation of cell motility GO:2000145 299 0.139
regulation of jun kinase activity GO:0043506 27 0.137
regulation of cytokine biosynthetic process GO:0042035 35 0.136
Mouse
interleukin 1 mediated signaling pathway GO:0070498 12 0.136
positive regulation of cellular component movement GO:0051272 181 0.134
positive regulation of kinase activity GO:0033674 204 0.133
positive regulation of b cell proliferation GO:0030890 12 0.133
positive regulation of mhc class ii biosynthetic process GO:0045348 3 0.128
regulation of cell growth GO:0001558 135 0.125
response to retinoic acid GO:0032526 33 0.124
regulation of leukocyte proliferation GO:0070663 67 0.124
Mouse
regulation of inflammatory response GO:0050727 46 0.123
Mouse
single organism nuclear import GO:1902593 104 0.123
regulation of interleukin 1 production GO:0032652 21 0.123
negative regulation of macrophage cytokine production GO:0010936 3 0.122
regulation of cellular component movement GO:0051270 334 0.122
regulation of leukocyte chemotaxis GO:0002688 46 0.121
positive regulation of dna binding GO:0043388 17 0.120
regulation of erk1 and erk2 cascade GO:0070372 99 0.120
negative regulation of protein kinase activity GO:0006469 98 0.120
macromolecule glycosylation GO:0043413 63 0.119
cellular protein catabolic process GO:0044257 261 0.119
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.115
positive regulation of cellular catabolic process GO:0031331 284 0.115
regulation of interleukin 6 biosynthetic process GO:0045408 5 0.115
protein localization to nucleus GO:0034504 136 0.111
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.110
positive regulation of blood coagulation GO:0030194 11 0.109
regulation of cell cycle GO:0051726 393 0.108
b cell activation GO:0042113 33 0.108
macrophage cytokine production GO:0010934 4 0.108
establishment of protein localization to organelle GO:0072594 172 0.106
positive regulation of protein binding GO:0032092 24 0.106
reactive oxygen species biosynthetic process GO:1903409 4 0.105
positive regulation of leukocyte proliferation GO:0070665 48 0.105
Mouse
positive regulation of developmental process GO:0051094 314 0.105
adaptive immune response GO:0002250 49 0.104
Mouse
leukotriene metabolic process GO:0006691 10 0.104
positive regulation of leukocyte activation GO:0002696 80 0.101
Mouse
lipid localization GO:0010876 106 0.101
digestive system process GO:0022600 17 0.098
regulation of growth GO:0040008 165 0.096
Mouse
organophosphate biosynthetic process GO:0090407 163 0.096
regulation of chemokine c x c motif ligand 2 production GO:2000341 2 0.095
regulation of sensory perception GO:0051931 3 0.094
organic hydroxy compound metabolic process GO:1901615 147 0.093
protein complex disassembly GO:0043241 52 0.093
growth GO:0040007 202 0.091
Mouse
regulation of blood coagulation GO:0030193 42 0.091
regulation of b cell proliferation GO:0030888 18 0.090
nucleoside phosphate biosynthetic process GO:1901293 109 0.090
glycoprotein metabolic process GO:0009100 110 0.089
chemical homeostasis GO:0048878 306 0.087
lipid transport GO:0006869 90 0.086
protein glycosylation GO:0006486 62 0.085
purine nucleotide catabolic process GO:0006195 405 0.083
positive regulation of multi organism process GO:0043902 56 0.081
Fly
myd88 independent toll like receptor signaling pathway GO:0002756 2 0.080
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.080
b cell proliferation GO:0042100 22 0.080
regulation of proteolysis GO:0030162 293 0.079
positive regulation of intracellular protein transport GO:0090316 76 0.079
regulation of lipid transport GO:0032368 44 0.079
regulation of interleukin 12 biosynthetic process GO:0045075 1 0.079
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.078
modification dependent macromolecule catabolic process GO:0043632 212 0.077
toll like receptor 3 signaling pathway GO:0034138 4 0.074
negative regulation of growth of symbiont in host GO:0044130 1 0.074
Mouse
protein modification by small protein conjugation GO:0032446 342 0.074
regulation of binding GO:0051098 111 0.073
erk1 and erk2 cascade GO:0070371 104 0.073
positive regulation of binding GO:0051099 45 0.073
nucleoside triphosphate catabolic process GO:0009143 394 0.073
nucleoside triphosphate metabolic process GO:0009141 422 0.072
positive regulation of cell differentiation GO:0045597 211 0.072
regulation of toll like receptor 3 signaling pathway GO:0034139 2 0.072
cellular response to dna damage stimulus GO:0006974 379 0.071
positive regulation of immune effector process GO:0002699 40 0.070
Fly
regulation of cell migration GO:0030334 289 0.069
nucleotide biosynthetic process GO:0009165 109 0.069
muscle cell proliferation GO:0033002 35 0.069
Rat
hematopoietic or lymphoid organ development GO:0048534 186 0.069
positive regulation of smooth muscle cell proliferation GO:0048661 14 0.068
Rat
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.068
positive regulation of interleukin 4 biosynthetic process GO:0045404 1 0.066
regulation of interferon gamma production GO:0032649 36 0.065
response to peptide GO:1901652 65 0.065
antifungal humoral response GO:0019732 2 0.065
Fly
cell growth GO:0016049 160 0.064
protein maturation GO:0051604 233 0.064
primary neural tube formation GO:0014020 3 0.064
ribonucleoside catabolic process GO:0042454 406 0.064
cellular lipid metabolic process GO:0044255 303 0.063
regulation of type i interferon mediated signaling pathway GO:0060338 9 0.062
autophagy GO:0006914 88 0.062
response to corticosteroid GO:0031960 15 0.062
response to toxic substance GO:0009636 37 0.062
positive regulation of lymphocyte activation GO:0051251 73 0.061
Mouse
multi organism metabolic process GO:0044033 41 0.060
fatty acid derivative metabolic process GO:1901568 35 0.059
interleukin 12 biosynthetic process GO:0042090 1 0.059
b cell mediated immunity GO:0019724 10 0.058
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 391 0.056
macromolecular complex disassembly GO:0032984 60 0.056
neurological system process GO:0050877 163 0.056
interferon beta biosynthetic process GO:0045350 4 0.056
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.055
response to hypoxia GO:0001666 96 0.055
carbohydrate homeostasis GO:0033500 31 0.054
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.054
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 12 0.054
negative regulation of cell death GO:0060548 345 0.052
regulation of sensory perception of pain GO:0051930 3 0.052
modification dependent protein catabolic process GO:0019941 209 0.052
myeloid cell differentiation GO:0030099 117 0.051
nucleotide catabolic process GO:0009166 408 0.051
humoral immune response GO:0006959 49 0.051
Fly
cell cycle g1 s phase transition GO:0044843 80 0.051
ubiquitin dependent protein catabolic process GO:0006511 206 0.050
regulation of neutrophil chemotaxis GO:0090022 10 0.050
positive regulation of myeloid leukocyte cytokine production involved in immune response GO:0061081 1 0.050
regulation of nucleotide metabolic process GO:0006140 269 0.050
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.050
positive regulation of cell motility GO:2000147 177 0.049
response to acid chemical GO:0001101 66 0.048
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.048
microglial cell activation GO:0001774 2 0.048
regulation of reactive oxygen species metabolic process GO:2000377 41 0.048
reactive oxygen species metabolic process GO:0072593 75 0.047
system process GO:0003008 349 0.047
regulation of interleukin 2 production GO:0032663 19 0.047
circadian behavior GO:0048512 2 0.047
mrna stabilization GO:0048255 18 0.046
icosanoid metabolic process GO:0006690 35 0.046
positive regulation of chemotaxis GO:0050921 57 0.044
multicellular organismal movement GO:0050879 17 0.043
positive regulation of coagulation GO:0050820 11 0.042
protein acylation GO:0043543 138 0.041
purine containing compound biosynthetic process GO:0072522 88 0.041
extrinsic apoptotic signaling pathway GO:0097191 119 0.040
negative regulation of proteolysis GO:0045861 132 0.040
purine containing compound catabolic process GO:0072523 411 0.040
interaction with host GO:0051701 42 0.040
organophosphate catabolic process GO:0046434 430 0.039
granulocyte chemotaxis GO:0071621 37 0.039
wnt signaling pathway GO:0016055 156 0.039
embryo development GO:0009790 123 0.039

MYD88 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.854
disease of cellular proliferation DOID:14566 174 0.854
parasitic infectious disease DOID:1398 16 0.846
malaria DOID:12365 16 0.846
disease by infectious agent DOID:0050117 34 0.846
parasitic protozoa infectious disease DOID:2789 16 0.846
organ system cancer DOID:0050686 164 0.737
retinal disease DOID:5679 118 0.721
retinal degeneration DOID:8466 89 0.721
sensory system disease DOID:0050155 203 0.721
eye and adnexa disease DOID:1492 150 0.721
nervous system disease DOID:863 431 0.721
eye disease DOID:5614 149 0.721
degeneration of macula and posterior pole DOID:2007 17 0.223
macular degeneration DOID:4448 20 0.223
age related macular degeneration DOID:10871 17 0.223
large intestine cancer DOID:5672 29 0.084
colon cancer DOID:219 25 0.084
gastrointestinal system cancer DOID:3119 52 0.084
intestinal cancer DOID:10155 29 0.084
colorectal cancer DOID:9256 29 0.084