IMP

Process View

Homo sapiens

10 genes annotated in human

regulation of neutrophil chemotaxis

Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of neutrophil chemotaxis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of neutrophil chemotaxis" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	1.000	Human
CCL5	chemokine (C-C motif) ligand 5	0.990	Human
IL8	interleukin 8	0.983
CCL4	chemokine (C-C motif) ligand 4	0.969	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.862
CCR7	chemokine (C-C motif) receptor 7	0.820
CCL2	chemokine (C-C motif) ligand 2	0.819	Human
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.795
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.652
CCL19	chemokine (C-C motif) ligand 19	0.647
CCL8	chemokine (C-C motif) ligand 8	0.614	Human
IL1B	interleukin 1, beta	0.585	Rat
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.542
CCR4	chemokine (C-C motif) receptor 4	0.539	Human
IFNG	interferon, gamma	0.461
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.458	Human
PLEK	pleckstrin	0.445
CCL20	chemokine (C-C motif) ligand 20	0.430	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.396
IL6	interleukin 6 (interferon, beta 2)	0.386
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.383
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.358	Human
IL2RB	interleukin 2 receptor, beta	0.337
CXCL3	chemokine (C-X-C motif) ligand 3	0.321
CCR1	chemokine (C-C motif) receptor 1	0.305	Human
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.295
CCL7	chemokine (C-C motif) ligand 7	0.289	Human
CCL3	chemokine (C-C motif) ligand 3	0.285	Human
CCL22	chemokine (C-C motif) ligand 22	0.281	Human
CCL13	chemokine (C-C motif) ligand 13	0.274	Human
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.269
CXCL13	chemokine (C-X-C motif) ligand 13	0.266
CXCL10	chemokine (C-X-C motif) ligand 10	0.259
DPP4	dipeptidyl-peptidase 4	0.186
TNF	tumor necrosis factor	0.185
NCF2	neutrophil cytosolic factor 2	0.169
JAM2	junctional adhesion molecule 2	0.155	Human
PLAUR	plasminogen activator, urokinase receptor	0.145
TLR2	toll-like receptor 2	0.132
RGS1	regulator of G-protein signaling 1	0.129
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.125
ICAM1	intercellular adhesion molecule 1	0.103
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.099
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.095
IL2RG	interleukin 2 receptor, gamma	0.083
VCAM1	vascular cell adhesion molecule 1	0.082
IRF4	interferon regulatory factor 4	0.079
JAM3	junctional adhesion molecule 3	0.070
SELE	selectin E	0.067
IL7R	interleukin 7 receptor	0.064
SLAMF7	SLAM family member 7	0.062
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.062
IL10RA	interleukin 10 receptor, alpha	0.061
BCL2A1	BCL2-related protein A1	0.061
CXCL5	chemokine (C-X-C motif) ligand 5	0.058
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.057
VCAN	versican	0.057
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.057
CXCL11	chemokine (C-X-C motif) ligand 11	0.055
AQP9	aquaporin 9	0.051
MYD88	myeloid differentiation primary response gene (88)	0.050
PDZK1	PDZ domain containing 1	0.049
TLR4	toll-like receptor 4	0.048
SOCS3	suppressor of cytokine signaling 3	0.048
IRAK4	interleukin-1 receptor-associated kinase 4	0.044
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.043
CD93	CD93 molecule	0.043
CD40LG	CD40 ligand	0.042
CD83	CD83 molecule	0.039
TREM1	triggering receptor expressed on myeloid cells 1	0.039
CLEC7A	C-type lectin domain family 7, member A	0.038
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.038
IL1RN	interleukin 1 receptor antagonist	0.038
IL1R2	interleukin 1 receptor, type II	0.038
CD48	CD48 molecule	0.035
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.034
IL18RAP	interleukin 18 receptor accessory protein	0.033
GYPC	glycophorin C (Gerbich blood group)	0.032
CCR6	chemokine (C-C motif) receptor 6	0.031	Human
IL1R1	interleukin 1 receptor, type I	0.031
DPT	dermatopontin	0.030
CCL11	chemokine (C-C motif) ligand 11	0.030	Human
TGFB1	transforming growth factor, beta 1	0.029
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.028
CXCR5	chemokine (C-X-C motif) receptor 5	0.028	Human
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.028
SOD2	superoxide dismutase 2, mitochondrial	0.028
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.028
IDE	insulin-degrading enzyme	0.027
CD86	CD86 molecule	0.026
CXCR2	chemokine (C-X-C motif) receptor 2	0.025	Human Rat
CD163	CD163 molecule	0.024
CCR3	chemokine (C-C motif) receptor 3	0.024	Human
CXCR3	chemokine (C-X-C motif) receptor 3	0.024	Human
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.024
PLAU	plasminogen activator, urokinase	0.023
IL10	interleukin 10	0.020
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.020
FPR1	formyl peptide receptor 1	0.020
INHBA	inhibin, beta A	0.020
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.020
CH25H	cholesterol 25-hydroxylase	0.020
IL1A	interleukin 1, alpha	0.019
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.019
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.019
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.018
CCL21	chemokine (C-C motif) ligand 21	0.018
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.018
CYBB	cytochrome b-245, beta polypeptide	0.018
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.018
EBI3	Epstein-Barr virus induced 3	0.017
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.016
MNDA	myeloid cell nuclear differentiation antigen	0.016
CYTIP	cytohesin 1 interacting protein	0.016
IL21R	interleukin 21 receptor	0.016
IL4	interleukin 4	0.015
IL2RA	interleukin 2 receptor, alpha	0.015
SELP	selectin P (granule membrane protein 140kDa, antigen CD62)	0.015
ADAMDEC1	ADAM-like, decysin 1	0.015
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.015
DARC	Duffy blood group, chemokine receptor	0.014
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.014
C3AR1	complement component 3a receptor 1	0.014	Mouse
CLEC4E	C-type lectin domain family 4, member E	0.014
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.013
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.013
SLAMF8	SLAM family member 8	0.013
C5AR1	complement component 5a receptor 1	0.013	Mouse
CD80	CD80 molecule	0.012
GPR84	G protein-coupled receptor 84	0.012
GPR109B	G protein-coupled receptor 109B	0.012
CCRL2	chemokine (C-C motif) receptor-like 2	0.012	Human
CLEC5A	C-type lectin domain family 5, member A	0.012
CCR8	chemokine (C-C motif) receptor 8	0.012	Human
IRAK1	interleukin-1 receptor-associated kinase 1	0.011
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.011
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.011
CD6	CD6 molecule	0.011
SFRP4	secreted frizzled-related protein 4	0.010
CCR9	chemokine (C-C motif) receptor 9	0.010	Human
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.010
EDN1	endothelin 1	0.010	Rat