IMP

Process View

Homo sapiens

4 genes annotated in human

regulation of interferon alpha biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-alpha.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of interferon alpha biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of interferon alpha biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	1.000
MYD88	myeloid differentiation primary response gene (88)	0.999
TICAM2	toll-like receptor adaptor molecule 2	0.769
TLR2	toll-like receptor 2	0.342
LY86	lymphocyte antigen 86	0.330
BTK	Bruton agammaglobulinemia tyrosine kinase	0.270
VNN2	vanin 2	0.208
CCR1	chemokine (C-C motif) receptor 1	0.180
FGL2	fibrinogen-like 2	0.168
RNASE6	ribonuclease, RNase A family, k6	0.146
TFEC	transcription factor EC	0.133
P2RY13	purinergic receptor P2Y, G-protein coupled, 13	0.129
IGSF6	immunoglobulin superfamily, member 6	0.114
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.109
CD86	CD86 molecule	0.106
TLR1	toll-like receptor 1	0.105	Human
IRAK2	interleukin-1 receptor-associated kinase 2	0.082
TLR4	toll-like receptor 4	0.074	Human
SYK	spleen tyrosine kinase	0.069
CD163	CD163 molecule	0.065
CYBB	cytochrome b-245, beta polypeptide	0.064
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.063
IRAK3	interleukin-1 receptor-associated kinase 3	0.060
EVI2B	ecotropic viral integration site 2B	0.056
TLR7	toll-like receptor 7	0.051
TLR6	toll-like receptor 6	0.051	Human
CLEC7A	C-type lectin domain family 7, member A	0.049
EVI2A	ecotropic viral integration site 2A	0.046
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.042
LRMP	lymphoid-restricted membrane protein	0.037
MARCH1	membrane-associated ring finger (C3HC4) 1	0.037
C3AR1	complement component 3a receptor 1	0.032
IRAK1	interleukin-1 receptor-associated kinase 1	0.031
MSR1	macrophage scavenger receptor 1	0.031
CCR2	chemokine (C-C motif) receptor 2	0.030
MS4A7	membrane-spanning 4-domains, subfamily A, member 7	0.028
SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7	0.028
CTSS	cathepsin S	0.026
SLFN12	schlafen family member 12	0.025
KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.023
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.023
GPR65	G protein-coupled receptor 65	0.022
IRF8	interferon regulatory factor 8	0.022
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.022
GPR18	G protein-coupled receptor 18	0.022
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.022
MNDA	myeloid cell nuclear differentiation antigen	0.020
PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.020
SELL	selectin L	0.019
DHRS9	dehydrogenase/reductase (SDR family) member 9	0.019
ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1	0.019
CD180	CD180 molecule	0.018	Human
BLNK	B-cell linker	0.018
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.017
NPL	N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)	0.017
PTAFR	platelet-activating factor receptor	0.017
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.015
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.015
IRAK4	interleukin-1 receptor-associated kinase 4	0.015
IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides	0.015
CYTIP	cytohesin 1 interacting protein	0.015
ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.015
CYSLTR1	cysteinyl leukotriene receptor 1	0.015
SASH3	SAM and SH3 domain containing 3	0.014
AIM2	absent in melanoma 2	0.014
MCTP1	multiple C2 domains, transmembrane 1	0.014
FPR3	formyl peptide receptor 3	0.014
C17orf60	chromosome 17 open reading frame 60	0.014
GPR34	G protein-coupled receptor 34	0.013
IFIH1	interferon induced with helicase C domain 1	0.013
MR1	major histocompatibility complex, class I-related	0.013
RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.013
TLR5	toll-like receptor 5	0.013	Human
C13orf18	chromosome 13 open reading frame 18	0.013
RGS18	regulator of G-protein signaling 18	0.012
STAP1	signal transducing adaptor family member 1	0.012
CYTH4	cytohesin 4	0.012
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.011
CLEC4A	C-type lectin domain family 4, member A	0.011
BST1	bone marrow stromal cell antigen 1	0.011
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.011
TLR8	toll-like receptor 8	0.011
APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.011
SAMD9L	sterile alpha motif domain containing 9-like	0.011
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.011
STAP2	signal transducing adaptor family member 2	0.010
IL1RAP	interleukin 1 receptor accessory protein	0.010
BIN2	bridging integrator 2	0.010
CD1C	CD1c molecule	0.010