Homo sapiens

65 known processes

PDK1

pyruvate dehydrogenase kinase, isozyme 1

PDK1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
phospholipid translocation GO:0045332 2 0.684
cellular amino acid metabolic process GO:0006520 116 0.479
lipid metabolic process GO:0006629 381 0.375
Human Mouse
post embryonic development GO:0009791 2 0.230
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.220
organic anion transport GO:0015711 103 0.220
cellular ketone metabolic process GO:0042180 80 0.215
Human Mouse
cellular amine metabolic process GO:0044106 41 0.202
regulation of cellular amine metabolic process GO:0033238 11 0.202
lipid translocation GO:0034204 2 0.201
regulation of cellular ketone metabolic process GO:0010565 50 0.201
Human Mouse
determination of adult lifespan GO:0008340 2 0.199
peptidyl serine phosphorylation GO:0018105 101 0.199
Human Rat
maintenance of location GO:0051235 112 0.185
anion transport GO:0006820 161 0.180
regulation of cellular component movement GO:0051270 334 0.178
positive regulation of cellular amine metabolic process GO:0033240 7 0.173
negative regulation of programmed cell death GO:0043069 321 0.170
Human
regulation of apoptotic signaling pathway GO:2001233 175 0.169
multicellular organismal aging GO:0010259 3 0.164
cation transport GO:0006812 331 0.163
organophosphate ester transport GO:0015748 32 0.159
monocarboxylic acid metabolic process GO:0032787 185 0.159
Human Mouse
regulation of cellular amino acid metabolic process GO:0006521 6 0.150
oxidation reduction process GO:0055114 396 0.150
negative regulation of apoptotic signaling pathway GO:2001234 97 0.138
regulation of ion transport GO:0043269 189 0.135
positive regulation of cellular catabolic process GO:0031331 284 0.126
positive regulation of cellular component organization GO:0051130 376 0.126
regulation of cell motility GO:2000145 299 0.125
histone serine phosphorylation GO:0035404 4 0.123
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.123
response to abiotic stimulus GO:0009628 336 0.122
regulation of protein localization GO:0032880 296 0.119
amine metabolic process GO:0009308 44 0.119
cellular response to external stimulus GO:0071496 111 0.116
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.116
replicative cell aging GO:0001302 3 0.115
regulation of growth GO:0040008 165 0.114
negative regulation of cell death GO:0060548 345 0.113
Human
regulation of cellular component biogenesis GO:0044087 281 0.109
positive regulation of transport GO:0051050 336 0.107
peptidyl serine modification GO:0018209 106 0.106
Human Rat
female gamete generation GO:0007292 2 0.105
muscle contraction GO:0006936 73 0.103
metal ion transport GO:0030001 272 0.103
regulation of lipid biosynthetic process GO:0046890 47 0.102
Human
lipid biosynthetic process GO:0008610 177 0.102
Human
chemical homeostasis GO:0048878 306 0.102
positive regulation of catabolic process GO:0009896 310 0.102
coenzyme metabolic process GO:0006732 65 0.102
Human Mouse
negative regulation of apoptotic process GO:0043066 316 0.102
Human
regulation of locomotion GO:0040012 329 0.101
regulation of cell migration GO:0030334 289 0.099
cellular lipid metabolic process GO:0044255 303 0.097
Human Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.096
response to oxidative stress GO:0006979 121 0.095
positive regulation of ion transport GO:0043270 87 0.091
chromatin modification GO:0016568 298 0.091
single organism carbohydrate metabolic process GO:0044723 193 0.086
regulation of anatomical structure size GO:0090066 101 0.086
cellular response to oxidative stress GO:0034599 85 0.084
striated muscle contraction GO:0006941 52 0.084
oogenesis GO:0048477 2 0.084
protein maturation GO:0051604 233 0.084
response to biotic stimulus GO:0009607 276 0.083
positive regulation of developmental process GO:0051094 314 0.080
transcription from rna polymerase iii promoter GO:0006383 19 0.079
growth GO:0040007 202 0.079
neuromuscular junction development GO:0007528 3 0.077
extrinsic apoptotic signaling pathway GO:0097191 119 0.077
apoptotic signaling pathway GO:0097190 268 0.077
regulation of cellular component size GO:0032535 82 0.075
memory GO:0007613 3 0.074
regulation of muscle system process GO:0090257 53 0.073
actin filament based process GO:0030029 224 0.072
peptidyl lysine modification GO:0018205 144 0.070
behavior GO:0007610 112 0.069
transmembrane transport GO:0055085 399 0.069
protein autophosphorylation GO:0046777 123 0.069
regulation of system process GO:0044057 101 0.068
nucleotide biosynthetic process GO:0009165 109 0.065
positive regulation of organelle organization GO:0010638 195 0.065
negative regulation of cellular component organization GO:0051129 235 0.064
enzyme linked receptor protein signaling pathway GO:0007167 303 0.063
Human
muscle system process GO:0003012 81 0.063
membrane organization GO:0061024 292 0.063
internal peptidyl lysine acetylation GO:0018393 97 0.062
cation homeostasis GO:0055080 189 0.062
metal ion homeostasis GO:0055065 169 0.061
negative regulation of lipid metabolic process GO:0045833 38 0.061
positive regulation of programmed cell death GO:0043068 249 0.060
glycerolipid metabolic process GO:0046486 107 0.060
response to wounding GO:0009611 168 0.060
system process GO:0003008 349 0.060
chronological cell aging GO:0001300 2 0.059
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.058
negative regulation of hydrolase activity GO:0051346 182 0.058
membrane lipid metabolic process GO:0006643 53 0.058
ion homeostasis GO:0050801 230 0.058
negative regulation of catalytic activity GO:0043086 335 0.058
regulation of cell cycle GO:0051726 393 0.057
cellular component morphogenesis GO:0032989 314 0.057
negative regulation of cell proliferation GO:0008285 228 0.056
nucleotide catabolic process GO:0009166 408 0.056
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.056
divalent metal ion transport GO:0070838 152 0.054
response to organonitrogen compound GO:0010243 156 0.051
Human
histone modification GO:0016570 251 0.050
skeletal muscle tissue growth GO:0048630 2 0.050
regulation of ion homeostasis GO:2000021 73 0.050
regulation of transcription from rna polymerase iii promoter GO:0006359 13 0.050
cofactor metabolic process GO:0051186 87 0.050
Human Mouse
mitochondrion organization GO:0007005 156 0.049
glycerophospholipid metabolic process GO:0006650 84 0.049
response to nitrogen compound GO:1901698 184 0.049
Human
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.049
ribonucleotide catabolic process GO:0009261 405 0.049
intrinsic apoptotic signaling pathway GO:0097193 127 0.049
positive regulation of cell migration GO:0030335 172 0.049
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.049
negative regulation of cellular protein metabolic process GO:0032269 353 0.048
sequestering of calcium ion GO:0051208 17 0.048
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.048
positive regulation of growth GO:0045927 58 0.047
regulation of peptidase activity GO:0052547 180 0.047
regulation of secretion GO:0051046 194 0.047
lipid localization GO:0010876 106 0.047
purine ribonucleoside metabolic process GO:0046128 437 0.047
response to other organism GO:0051707 261 0.046
regulation of anatomical structure morphogenesis GO:0022603 286 0.046
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.046
ion transmembrane transport GO:0034220 338 0.046
protein processing GO:0016485 226 0.046
carbohydrate derivative biosynthetic process GO:1901137 207 0.046
regulation of endopeptidase activity GO:0052548 170 0.045
cation transmembrane transport GO:0098655 238 0.045
organophosphate catabolic process GO:0046434 430 0.045
single organism membrane organization GO:0044802 268 0.045
phospholipid transport GO:0015914 23 0.045
purine nucleoside triphosphate catabolic process GO:0009146 392 0.045
internal protein amino acid acetylation GO:0006475 101 0.045
cell morphogenesis GO:0000902 296 0.044
cellular ion homeostasis GO:0006873 168 0.044
neurological system process GO:0050877 163 0.044
positive regulation of apoptotic process GO:0043065 246 0.044
cellular response to hormone stimulus GO:0032870 125 0.044
Human
response to external biotic stimulus GO:0043207 261 0.044
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.044
regulation of proteolysis GO:0030162 293 0.043
negative regulation of lipid transport GO:0032369 18 0.043
lipid transport GO:0006869 90 0.043
vasculature development GO:0001944 181 0.041
sequestering of metal ion GO:0051238 24 0.041
nucleoside phosphate catabolic process GO:1901292 412 0.041
ribonucleoside triphosphate metabolic process GO:0009199 412 0.041
regulation of protein maturation GO:1903317 150 0.040
ribonucleoside triphosphate catabolic process GO:0009203 391 0.040
covalent chromatin modification GO:0016569 254 0.040
cellular response to dna damage stimulus GO:0006974 379 0.040
cardiovascular system development GO:0072358 262 0.040
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.040
positive regulation of protein phosphorylation GO:0001934 313 0.040
cellular modified amino acid metabolic process GO:0006575 64 0.040
purine ribonucleotide catabolic process GO:0009154 404 0.039
mitotic cell cycle process GO:1903047 286 0.039
regulation of membrane potential GO:0042391 95 0.039
chromatin organization GO:0006325 351 0.039
regulation of protein processing GO:0070613 150 0.039
regulation of purine nucleotide metabolic process GO:1900542 264 0.039
positive regulation of phosphorylation GO:0042327 394 0.038
negative regulation of protein maturation GO:1903318 142 0.038
cell aging GO:0007569 52 0.038
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.038
regulation of nucleotide metabolic process GO:0006140 269 0.038
somatic muscle development GO:0007525 1 0.037
cellular calcium ion homeostasis GO:0006874 117 0.037
actin cytoskeleton organization GO:0030036 207 0.037
anatomical structure formation involved in morphogenesis GO:0048646 284 0.037
positive regulation of cell death GO:0010942 263 0.037
positive regulation of cell cycle GO:0045787 140 0.037
regulation of cysteine type endopeptidase activity GO:2000116 127 0.036
cellular response to oxygen containing compound GO:1901701 276 0.036
Human
guanosine containing compound metabolic process GO:1901068 244 0.036
single organism cellular localization GO:1902580 332 0.036
response to nutrient levels GO:0031667 81 0.036
Human
regulation of homeostatic process GO:0032844 121 0.035
negative regulation of endopeptidase activity GO:0010951 84 0.035
response to hypoxia GO:0001666 96 0.035
regeneration GO:0031099 4 0.035
purine nucleoside triphosphate metabolic process GO:0009144 412 0.035
positive regulation of hormone biosynthetic process GO:0046886 4 0.035
purine nucleotide catabolic process GO:0006195 405 0.035
rho protein signal transduction GO:0007266 26 0.035
negative regulation of proteolysis GO:0045861 132 0.034
regulation of actin filament based process GO:0032970 141 0.034
circulatory system development GO:0072359 262 0.034
blood vessel development GO:0001568 172 0.034
response to cytokine GO:0034097 232 0.034
cell cycle phase transition GO:0044770 173 0.033
response to organic cyclic compound GO:0014070 204 0.033
positive regulation of cellular component movement GO:0051272 181 0.033
carbohydrate metabolic process GO:0005975 207 0.033
regulation of cellular response to stress GO:0080135 244 0.033
cellular chemical homeostasis GO:0055082 180 0.033
peptidyl lysine acetylation GO:0018394 101 0.033
positive regulation of transcription from rna polymerase iii promoter GO:0045945 10 0.033
membrane lipid biosynthetic process GO:0046467 27 0.032
response to lipid GO:0033993 206 0.032
Human
nucleoside catabolic process GO:0009164 408 0.032
phospholipid metabolic process GO:0006644 99 0.032
response to hormone GO:0009725 175 0.032
Human
protein acetylation GO:0006473 116 0.032
negative regulation of peptidase activity GO:0010466 91 0.032
positive regulation of locomotion GO:0040017 186 0.031
regulation of phospholipid transport GO:2001138 4 0.031
cytoplasmic transport GO:0016482 379 0.031
vesicle mediated transport GO:0016192 371 0.031
mitotic cell cycle GO:0000278 326 0.031
negative regulation of protein metabolic process GO:0051248 391 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.031
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 5 0.031
regulation of mitotic cell cycle GO:0007346 189 0.030
ribonucleoside catabolic process GO:0042454 406 0.030
negative regulation of phosphorus metabolic process GO:0010563 267 0.030
negative regulation of homeostatic process GO:0032845 59 0.030
positive regulation of cell proliferation GO:0008284 301 0.030
small molecule biosynthetic process GO:0044283 157 0.030
Human
purine containing compound catabolic process GO:0072523 411 0.030
response to extracellular stimulus GO:0009991 85 0.030
Human
regulation of response to external stimulus GO:0032101 222 0.029
epithelium migration GO:0090132 119 0.029
divalent inorganic cation transport GO:0072511 158 0.029
generation of precursor metabolites and energy GO:0006091 68 0.029
response to insulin GO:0032868 45 0.029
Human
response to oxygen containing compound GO:1901700 369 0.029
Human
response to oxygen levels GO:0070482 100 0.029
regulation of cell cycle process GO:0010564 266 0.029
positive regulation of mesonephros development GO:0061213 2 0.028
sphingolipid metabolic process GO:0006665 38 0.028
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 17 0.028
calcium ion homeostasis GO:0055074 122 0.028
negative regulation of protein processing GO:0010955 142 0.028
gtp metabolic process GO:0046039 239 0.028
cellular divalent inorganic cation homeostasis GO:0072503 128 0.028
cellular metal ion homeostasis GO:0006875 146 0.028
regulation of protein transport GO:0051223 213 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.027
Human
multi organism cellular process GO:0044764 156 0.027
positive regulation of cell size GO:0045793 3 0.027
small gtpase mediated signal transduction GO:0007264 78 0.027
regulation of nucleoside metabolic process GO:0009118 209 0.027
positive regulation of phospholipid transport GO:2001140 4 0.027
striated muscle adaptation GO:0014888 4 0.027
response to starvation GO:0042594 59 0.027
Human
pyruvate metabolic process GO:0006090 26 0.027
Human Mouse
regulation of anion transport GO:0044070 25 0.027
positive regulation of cellular component biogenesis GO:0044089 158 0.027
cell growth GO:0016049 160 0.027
cell activation GO:0001775 213 0.027
alpha amino acid metabolic process GO:1901605 72 0.026
regulation of response to osmotic stress GO:0047484 3 0.026
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.026
viral process GO:0016032 146 0.026
nucleocytoplasmic transport GO:0006913 176 0.026
cellular response to organonitrogen compound GO:0071417 124 0.026
Human
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.026
regulation of gtp catabolic process GO:0033124 180 0.026
regulation of establishment of protein localization GO:0070201 242 0.026
axon cargo transport GO:0008088 2 0.025
cellular response to nitrogen compound GO:1901699 144 0.025
Human
regulation of intracellular transport GO:0032386 195 0.025
secretion GO:0046903 254 0.025
cellular response to starvation GO:0009267 58 0.025
Human
protein localization to organelle GO:0033365 280 0.025
cellular homeostasis GO:0019725 196 0.025
negative regulation of ion transport GO:0043271 39 0.025
regulation of purine nucleotide catabolic process GO:0033121 205 0.025
regulation of cytokine production GO:0001817 232 0.025
cellular cation homeostasis GO:0030003 163 0.025
regulation of cell growth GO:0001558 135 0.025
fibroblast activation GO:0072537 3 0.024
actin mediated cell contraction GO:0070252 12 0.024
blood vessel morphogenesis GO:0048514 162 0.024
nucleoside phosphate biosynthetic process GO:1901293 109 0.024
regulation of glucose import GO:0046324 21 0.024
establishment of protein localization to organelle GO:0072594 172 0.024
regulation of chromatin modification GO:1903308 51 0.024
cellular response to abiotic stimulus GO:0071214 117 0.024
ras protein signal transduction GO:0007265 73 0.024
protein catabolic process GO:0030163 325 0.024
purine ribonucleoside catabolic process GO:0046130 398 0.024
response to decreased oxygen levels GO:0036293 96 0.024
nucleoside triphosphate catabolic process GO:0009143 394 0.024
regulation of angiogenesis GO:0045765 92 0.024
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.023
regulation of vasculature development GO:1901342 97 0.023
segmentation GO:0035282 4 0.023
histone acetylation GO:0016573 93 0.023
organic acid biosynthetic process GO:0016053 97 0.023
Human
regulation of cell activation GO:0050865 125 0.023
regulation of chromosome organization GO:0033044 103 0.023
response to virus GO:0009615 126 0.023
regulation of secretion by cell GO:1903530 177 0.023
regulation of muscle organ development GO:0048634 27 0.023
calcium ion transport GO:0006816 147 0.023
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.023
glycosyl compound catabolic process GO:1901658 413 0.023
angiogenesis GO:0001525 147 0.023
regulation of neural precursor cell proliferation GO:2000177 4 0.023
negative regulation of organelle organization GO:0010639 126 0.023
mitotic cell cycle phase transition GO:0044772 162 0.023
regulation of transmembrane transport GO:0034762 139 0.023
positive regulation of gtpase activity GO:0043547 166 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.022
cellular response to decreased oxygen levels GO:0036294 51 0.022
g protein coupled receptor signaling pathway GO:0007186 207 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
regulation of chromatin organization GO:1902275 56 0.022
regulation of muscle tissue development GO:1901861 26 0.022
regulation of wound healing GO:0061041 56 0.022
regulation of camp metabolic process GO:0030814 52 0.022
epithelium development GO:0060429 227 0.022
reactive oxygen species metabolic process GO:0072593 75 0.022
Human
response to steroid hormone GO:0048545 80 0.022
tissue regeneration GO:0042246 3 0.022
protein kinase b signaling GO:0043491 69 0.022
response to osmotic stress GO:0006970 17 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.021
cdc42 protein signal transduction GO:0032488 4 0.021
purine nucleoside catabolic process GO:0006152 398 0.021
response to peptide GO:1901652 65 0.021
Human
epidermis morphogenesis GO:0048730 3 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.021
hexose metabolic process GO:0019318 55 0.021
translation GO:0006412 132 0.021
biological adhesion GO:0022610 331 0.021
response to nutrient GO:0007584 20 0.021
negative regulation of cell cycle GO:0045786 193 0.021
developmental growth GO:0048589 48 0.021
response to electrical stimulus GO:0051602 1 0.021
positive regulation of mitotic cell cycle GO:0045931 60 0.021
ribonucleoside monophosphate metabolic process GO:0009161 187 0.021
cellular response to endogenous stimulus GO:0071495 336 0.021
Human
regulation of cytoplasmic transport GO:1903649 149 0.020
cellular macromolecule catabolic process GO:0044265 380 0.020
ribonucleotide biosynthetic process GO:0009260 81 0.020
circulatory system process GO:0003013 113 0.020
taxis GO:0042330 157 0.020
immune system development GO:0002520 195 0.020
regulation of autophagy GO:0010506 52 0.020
skeletal muscle contraction GO:0003009 16 0.020
cellular response to extracellular stimulus GO:0031668 72 0.020
Human
regulation of mesonephros development GO:0061217 3 0.020
innate immune response GO:0045087 178 0.020
dephosphorylation GO:0016311 209 0.020
nucleoside triphosphate metabolic process GO:0009141 422 0.020
glycoprotein metabolic process GO:0009100 110 0.020
histone h2a phosphorylation GO:1990164 3 0.020
locomotory behavior GO:0007626 1 0.020
regulation of actin cytoskeleton organization GO:0032956 116 0.020
regulation of dna templated transcription in response to stress GO:0043620 18 0.020
ameboidal type cell migration GO:0001667 135 0.020
regulation of lipid transport GO:0032368 44 0.020
cellular response to insulin stimulus GO:0032869 41 0.019
Human
regulation of protein complex assembly GO:0043254 147 0.019
regulation of nucleotide catabolic process GO:0030811 205 0.019
regulation of kinase activity GO:0043549 314 0.019
cardiac muscle contraction GO:0060048 34 0.019
vacuole organization GO:0007033 44 0.019
purine ribonucleotide biosynthetic process GO:0009152 79 0.019
camp metabolic process GO:0046058 61 0.019
musculoskeletal movement GO:0050881 17 0.019
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.019
hematopoietic stem cell differentiation GO:0060218 4 0.019
adult locomotory behavior GO:0008344 1 0.019
associative learning GO:0008306 1 0.019
positive regulation of protein kinase activity GO:0045860 190 0.019
positive regulation of cytoplasmic transport GO:1903651 82 0.019
response to bacterium GO:0009617 144 0.019
regulation of ion transmembrane transport GO:0034765 132 0.019
positive regulation of immune system process GO:0002684 283 0.019
organelle assembly GO:0070925 176 0.019
immune response GO:0006955 307 0.019
signal transduction in response to dna damage GO:0042770 57 0.019
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 2 0.019
atp metabolic process GO:0046034 176 0.019
mapk cascade GO:0000165 288 0.019
cell projection organization GO:0030030 252 0.019
aging GO:0007568 66 0.018
regulation of heart contraction GO:0008016 50 0.018
interspecies interaction between organisms GO:0044419 156 0.018
positive regulation of mapk cascade GO:0043410 190 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
defense response GO:0006952 315 0.018
epithelial cell migration GO:0010631 119 0.018
regulation of histone modification GO:0031056 47 0.018
regulation of endothelial cell differentiation GO:0045601 4 0.018
wound healing GO:0042060 115 0.018
nucleoside monophosphate metabolic process GO:0009123 191 0.018
cell type specific apoptotic process GO:0097285 125 0.018
coenzyme biosynthetic process GO:0009108 24 0.018
Human Mouse
histone h2a s1 phosphorylation GO:0043990 1 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
protein localization to membrane GO:0072657 160 0.018
myoblast fusion GO:0007520 1 0.018
chemotaxis GO:0006935 157 0.018
regulation of gtpase activity GO:0043087 180 0.018
regulation of growth rate GO:0040009 1 0.018
rna processing GO:0006396 255 0.018
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.018
endocytosis GO:0006897 159 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
negative regulation of monocyte differentiation GO:0045656 3 0.018
purine nucleotide biosynthetic process GO:0006164 84 0.018
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.018
purine containing compound biosynthetic process GO:0072522 88 0.018
positive regulation of gtp catabolic process GO:0033126 166 0.017
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.017
regulation of cell adhesion GO:0030155 166 0.017
cellular protein catabolic process GO:0044257 261 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.017
cell matrix adhesion GO:0007160 85 0.017
cellular response to cytokine stimulus GO:0071345 181 0.017
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.017
tissue migration GO:0090130 119 0.017
cellular protein complex assembly GO:0043623 188 0.017
spinal cord development GO:0021510 4 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
muscle cell migration GO:0014812 19 0.017
carboxylic acid biosynthetic process GO:0046394 97 0.017
Human
nuclear transport GO:0051169 179 0.017
negative regulation of lipid biosynthetic process GO:0051055 22 0.017
divalent inorganic cation homeostasis GO:0072507 136 0.017
positive regulation of response to external stimulus GO:0032103 88 0.017
epithelial cell differentiation GO:0030855 141 0.017
leukocyte migration GO:0050900 107 0.017
dicarboxylic acid biosynthetic process GO:0043650 4 0.017
regulation of axon guidance GO:1902667 3 0.016
monosaccharide metabolic process GO:0005996 74 0.016
sulfur compound biosynthetic process GO:0044272 38 0.016
Human Mouse
secretion by cell GO:0032940 226 0.016
cellular response to peptide hormone stimulus GO:0071375 56 0.016
Human
regulation of transferase activity GO:0051338 355 0.016
reactive nitrogen species metabolic process GO:2001057 3 0.016
regulation of response to drug GO:2001023 3 0.016
regulation of ras gtpase activity GO:0032318 128 0.016
actin filament based movement GO:0030048 17 0.016
viral life cycle GO:0019058 132 0.016
intracellular protein transport GO:0006886 270 0.016
response to axon injury GO:0048678 1 0.016
neuron differentiation GO:0030182 138 0.016
generation of neurons GO:0048699 152 0.016
developmental programmed cell death GO:0010623 3 0.016
response to alcohol GO:0097305 64 0.016
signal transduction in absence of ligand GO:0038034 22 0.016
photoreceptor cell differentiation GO:0046530 2 0.016
cell morphogenesis involved in differentiation GO:0000904 144 0.016
urea metabolic process GO:0019627 3 0.016
vasodilation GO:0042311 4 0.016
positive regulation of transferase activity GO:0051347 227 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
regulation of histone acetylation GO:0035065 19 0.015
regulation of protein kinase activity GO:0045859 289 0.015
histone phosphorylation GO:0016572 16 0.015
peripheral nervous system development GO:0007422 2 0.015
hemopoiesis GO:0030097 180 0.015
mitochondrial membrane organization GO:0007006 40 0.015
positive regulation of neural precursor cell proliferation GO:2000179 2 0.015
salivary gland morphogenesis GO:0007435 4 0.015
purine nucleoside monophosphate catabolic process GO:0009128 158 0.015
carbohydrate transport GO:0008643 37 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
negative regulation of alpha beta t cell activation GO:0046636 3 0.015
patterning of blood vessels GO:0001569 2 0.015
regulation of sphingolipid biosynthetic process GO:0090153 2 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
organic hydroxy compound metabolic process GO:1901615 147 0.015
plasma membrane organization GO:0007009 115 0.015
regulation of neuroblast proliferation GO:1902692 3 0.015
response to nitric oxide GO:0071731 4 0.015
cell substrate adhesion GO:0031589 132 0.015
chemical homeostasis within a tissue GO:0048875 3 0.015
regulation of transmembrane transporter activity GO:0022898 74 0.015

PDK1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.032
disease of cellular proliferation DOID:14566 174 0.027
cancer DOID:162 167 0.027
organ system cancer DOID:0050686 164 0.027
immune system disease DOID:2914 155 0.020
inherited metabolic disorder DOID:655 242 0.020
acquired metabolic disease DOID:0060158 58 0.019